Stuart Turvey, MBBS, DPhil, FRCPC is a Professor of Pediatrics at the University of British Columbia where he holds the Aubrey J. Tingle Professorship in Pediatric Immunology. He is a Pediatric Immunologist based at BC Children’s Hospital, and Director of Clinical Research at the Child & Family Research Institute. Prior to coming to Vancouver, Dr Turvey completed both his Pediatric Residency and Allergy/Immunology Fellowship at Children’s Hospital, Harvard Medical School, Boston. He holds a medical degree (MB BS) from the University of Sydney, Australia and a doctorate (DPhil) in Immunology from Oxford University where he was a Rhodes Scholar. Dr Turvey is a Fellow of the Royal College of Physicians and Surgeons of Canada and a Diplomate of the American Board of Pediatrics.
Dr Turvey provides clinical care in the specialties of Clinical Immunology and Rheumatology, while his research program focuses on pediatric infectious and inflammatory diseases. Specifically, Dr Turvey is interested in the role of innate immunity in protecting infants and young children from infectious agents, and how abnormalities of the innate immune system contribute to inflammatory diseases of childhood.
• Innate immunity
• Host defense
• Primary immunodeficiency diseases (PIDs)
• Role of Toll-like receptors in human disease
• Airway inflammation in cystic fibrosis
• Asthma and allergic disease
Despite much effort, we know little about how the healthy child is protected from infectious disease, and even less about why some children develop inflammatory disorders. Why do some healthy children succumb to overwhelming bacterial infection, while others either survive infection or do not become infected at all? Why do some children suffer crippling juvenile arthritis or life-threatening asthma?
My research program is translational, interdisciplinary and unique in its focus on understanding the role of innate immunity in infectious and inflammatory diseases of childhood. Starting with a population of children with a defined infectious or inflammatory disease phenotype (e.g., undue susceptibility to infection, juvenile idiopathic arthritis, asthma), I aim to determine the underlying cellular, molecular and genetic abnormalities responsible for the disease through detailed immunological, genomic and proteomic analysis. The new knowledge generated by this approach will aid diagnosis, elucidate mechanisms of disease pathogenesis and, ultimately, identify novel targets for anti-inflammatory and anti-infectious therapeutic agents.