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Works (17)

Synaptic gene expression changes in frontotemporal dementia due to the <i>MAPT</i> 10 + 16 mutation

Neuropathology and Applied Neurobiology
2024-08 | Journal article
DOI: 10.1111/nan.13006
Part of ISSN: 0305-1846
Part of ISSN: 1365-2990
Contributors: Owen Dando; Robert McGeachan; Jamie McQueen; Paul Baxter; Nathan Rockley; Hannah McAlister; Adharsh Prasad; Xin He; Declan King; Jamie Rose et al.
Source: Self-asserted source
Robert McGeachan

p-tau Ser356 is associated with Alzheimer’s disease pathology and is lowered in brain slice cultures using the NUAK inhibitor WZ4003

Acta Neuropathologica
2024-06 | Journal article
DOI: 10.1007/s00401-023-02667-w
Contributors: Lewis W. Taylor; Elizabeth M. Simzer; Claire Pimblett; Oscar T. T. Lacey-Solymar; Robert I. McGeachan; Soraya Meftah; Jamie L. Rose; Maxwell P. Spires-Jones; Kristján Holt; James H. Catterson et al.
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Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer’s disease

Acta Neuropathologica
2024-06 | Journal article
DOI: 10.1007/s00401-023-02679-6
Part of ISSN: 0001-6322
Part of ISSN: 1432-0533
Contributors: Martí Colom-Cadena; Jamie Toombs; Elizabeth Simzer; Kristjan Holt; Robert McGeachan; Jane Tulloch; Rosemary J. Jackson; James H. Catterson; Maxwell P. Spires-Jones; Jamie Rose et al.
Source: Self-asserted source
Robert McGeachan

Phylogenetic divergence of GABABreceptor signalling in neocortical networks over adult life

2024-06-05 | Preprint
DOI: 10.1101/2024.06.04.597285
Contributors: Max A. Wilson; Lewis W. Taylor; Soraya Meftah; Robert I. McGeachan; Tamara Modebadze; B. Ashan P. Jayasekera; Christopher J. A. Cowie; Fiona E. N. LeBeau; Imran Liaquat; Claire S. Durrant et al.
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Opposing roles of physiological and pathological amyloid-β on synapses in live human brain slice cultures

2024-02-21 | Preprint
DOI: 10.1101/2024.02.16.580676
Contributors: Robert I. McGeachan; Soraya Meftah; Lewis W. Taylor; James H. Catterson; Danilo Negro; Jane Tulloch; Jamie L. Rose; Francesco Gobbo; Imran Liaquat; Tara L. Spires-Jones et al.
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Clinical course in corticobasal syndrome and corticobasal degeneration: implications for diagnosis and management

Brain Communications
2023-11-01 | Journal article
DOI: 10.1093/braincomms/fcad321
Contributors: Robert I McGeachan; Declan King
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Tau phosphorylated at serine 356 is associated with Alzheimer’s disease pathology and can be lowered in mouse and human brain tissue using the NUAK inhibitor WZ4003

2023-08-29 | Preprint
DOI: 10.1101/2023.08.28.553851
Contributors: Lewis W. Taylor; Elizabeth M. Simzer; Claire Pimblett; Oscar T.T. Lacey-Solymar; Robert I. McGeachan; Soraya Meftah; Jamie L. Rose; Maxwell P. Spires-Jones; James H. Catterson; Henner Koch et al.
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Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain

Neuron
2023-05-15 | Journal article
DOI: 10.1016/j.neuron.2023.04.020
Part of ISSN: 0896-6273
Contributors: Martí Colom-Cadena; Caitlin Davies; Sònia Sirisi; Ji-Eun Lee; Elizabeth M. Simzer; Makis Tzioras; Marta Querol-Vilaseca; Érika Sánchez-Aced; Ya Yin Chang; Kristjan Holt et al.
Source: Self-asserted source
Robert McGeachan

Predictive blood biomarkers and brain changes associated with age-related cognitive decline

Brain Communications
2023-05-02 | Journal article
DOI: 10.1093/braincomms/fcad113
Contributors: Tyler S Saunders; Francesca E Pozzolo; Amanda Heslegrave; Declan King; Robert I McGeachan; Maxwell P Spires-Jones; Sarah E Harris; Craig Ritchie; Graciela Muniz-Terrera; Ian J Deary et al.
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Synaptic degeneration in Alzheimer disease

Nature Reviews Neurology
2023-01 | Journal article
DOI: 10.1038/s41582-022-00749-z
Contributors: Makis Tzioras; Robert I. McGeachan; Claire S. Durrant; Tara L. Spires-Jones
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Evidence for trans-synaptic propagation of oligomeric tau in Progressive Supranuclear Palsy

2022-09-20 | Preprint
DOI: 10.1101/2022.09.20.22280086
Contributors: Robert I McGeachan; Lois Keavey; Jamie L Rose; Elizabeth M Simzer; Ya Yin Chang; Maxwell P Spires-Jones; Mollie Gilmore; Natalia Ravingerova; Cristina Scutariu; Lewis Taylor et al.
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Integrated methylome and phenome study of the circulating proteome reveals markers pertinent to brain health

Nature Communications
2022-08-09 | Journal article
DOI: 10.1038/s41467-022-32319-8
Contributors: Danni A. Gadd; Robert F. Hillary; Daniel L. McCartney; Liu Shi; Aleks Stolicyn; Neil A. Robertson; Rosie M. Walker; Robert I. McGeachan; Archie Campbell; Shen Xueyi et al.
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Characterizing the molecular and immune landscape of canine bladder cancer

Veterinary and Comparative Oncology
2022-03 | Journal article
DOI: 10.1111/vco.12740
Contributors: Kathryn E. Cronise; Sunetra Das; Belen G. Hernandez; Daniel P. Regan; Deanna D. Dailey; Robert I. McGeachan; Susan E. Lana; Rodney L. Page; Daniel L. Gustafson; Dawn L. Duval
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The genetic and epigenetic profile of serum S100β in the Lothian Birth Cohort 1936 and its relationship to Alzheimer’s disease

Wellcome Open Research
2022-01-27 | Journal article
DOI: 10.12688/wellcomeopenres.17322.2
Contributors: Danni A Gadd; Robert I McGeachan; Robert F Hillary; Daniel L McCartney; Sarah E Harris; Roy A Sherwood; N Joan Abbott; Simon R Cox; Riccardo E Marioni
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The genetic and epigenetic profile of serum S100β in the Lothian Birth Cohort 1936 and its relationship to Alzheimer’s disease [version 1; peer review: 2 approved]

2021-11-10 | Journal article
DOI: 10.12688/wellcomeopenres.17322.1
Part of ISSN: 2398-502X
Funded by GRANT_NUMBER:

(Pilot Fund award)

Funded by GRANT_NUMBER:

108890/Z/15/Z

Funded by GRANT_NUMBER:

221890/Z/20/Z

Funded by GRANT_NUMBER:

ARUK-PG2017B−10

Funded by GRANT_NUMBER:

AS-PG-19b-010

Funded by GRANT_NUMBER:

BB/F019394/1

Funded by GRANT_NUMBER:

G0701120, G1001245, MR/M013111/1, MR/R024065/1

Funded by GRANT_NUMBER:

MR/K026992/1

Funded by GRANT_NUMBER:

R01AG054628 and R01AG05462802S1

Funded by GRANT_NUMBER:

[Grant code unknown]
Contributors: Danni A Gadd; Robert I McGeachan; Robert F Hillary; Daniel L McCartney; Sarah E Harris; Roy A Sherwood; N Joan Abbott; Simon R Cox; Riccardo E Marioni; A Gadd Danni et al.
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Wellcome Open Research
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Preferred source (of 2)‎

Integrated methylome and phenome study of the circulating proteome reveals markers pertinent to brain health

2021-09-06 | Preprint
DOI: 10.1101/2021.09.03.21263066
Contributors: Danni A Gadd; Robert F Hillary; Daniel L McCartney; Liu Shi; Aleks Stolicyn; Neil Robertson; Rosie M Walker; Robert I McGeachan; Archie Campbell; Shen Xueyi et al.
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Crossref

Botulinum toxin type A for the treatment of muscle contractures secondary to acute spinal cord injury in a young cat

Journal of Feline Medicine and Surgery Open Reports
2020-01 | Journal article
DOI: 10.1177/2055116920922648
Contributors: Robert I McGeachan; Tobias Schwarz; Danièlle A Gunn-Moore; Katia Marioni-Henry
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