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Employment (2)

PUCV: Valparaíso, CL

2022-08-01 to 2024-07-31 | Profesor asociado: Investigación y Docencia (Escuela de Tecnología Médica, Facultad de ciencias.)
Employment
Source: Self-asserted source
Cristian Cortez

Universidad Mayor: Santiago, CL

2016-01-11 to 2022-07-31 | Investigador y docente (Centro de Genómica y Bioinformática)
Employment
Source: Self-asserted source
Cristian Cortez

Education and qualifications (3)

Universidade Federal de Sao Paulo Escola Paulista de Medicina: Sao Paulo, SP, BR

2013-03-01 to 2015-12-31 | Ph.D. and Postdoctoral fellow (Microbiología, inmunología y parasitología)
Education
Source: Self-asserted source
Cristian Cortez

Universidade Federal de Sao Paulo Escola Paulista de Medicina: Sao Paulo, SP, BR

2008-03-01 to 2013-02-20 | Ph.D en Ciencias, mención microbiología e inmunología (Microbiología, inmunología y parasitología)
Education
Source: Self-asserted source
Cristian Cortez

Universidad de Antofagasta: Antofagasta, Segunda Región, CL

1995-03-01 to 2000-01-22 | Licenciado en Tecnología Médica (Tecnología Médica)
Education
Source: Self-asserted source
Cristian Cortez

Professional activities (5)

International Association for Dental Research: Santiago, IADR, División Chile, CL

2018-08-18 | Profesor tutor de tesis, autor corresponsal. Primer lugar presentación de poster en la categoría alumnos de pregrado (Premio Curaprox, 2018)
Distinction
Source: Self-asserted source
Cristian Cortez

Federación Latinoamericana de Parasitología: U. de Chile - Santiago, CL

2017-12 | Investigador senior: Premio primer lugar trabajos libres. XXIV Congreso latinoamericano de parasitologia (FLAP2017).
Distinction
Source: Self-asserted source
Cristian Cortez

Brazilian Society of Protozoology: Caxambu, BR

2015-11 | Investigador postdoctoral: Premio Zigman Brener. Mejor poster en Biología Celular, presentado durante XXXI Annual Meeting of the Brazilian Society of Protozoology / XLII Annual Meeting on Basic Rasearch.
Distinction
Source: Self-asserted source
Cristian Cortez

University of Brasilia: Brasilia, BR

2014-05 | Investigador postdoctoral: Premio Wladimir Lobato Paraense, mejor trabajo y presentación de poster en el 1st Host – Pathogen Interactions Meeting
Distinction
Source: Self-asserted source
Cristian Cortez

Brazilian Society of Protozoology: Foz de Iguacu, BR

2011-09 | Estudiante de doctorado: Premio Zigman Brener. Mejor poster en Biología Celular, presentado durante XXVII Annual Meeting of the Brazilian Society of Protozoology / XXXVIII Annual Meeting on Basic Rasearch in Chagas´ Disease
Distinction
Source: Self-asserted source
Cristian Cortez

Funding (4)

The therapeutic effects of RA-induced Treg-derived extracellular vesicles in periodontitis: Inhibition of alveolar bone resorption and promotion of its formation through the modulation of the periodontal immune response

2022-08 to 2026-08 | Grant
ANID (Santiago, CL)
GRANT_NUMBER:

Fondecyt regular 1220999 Co-investigador
Source: Self-asserted source
Cristian Cortez

Addressing the role of autophagy in the periodontitis pathogenesis

2019-11 to 2022-11 | Grant
CONICYT (Santiago, CL)
GRANT_NUMBER:

11190073
Source: Self-asserted source
Cristian Cortez

Fatores envolvidos na migração pela mucina gástrica e na invasão celular de formas metacíclicas do Trypanosoma cruzi

2013 to 2016 | Grant
Fundação de Amparo à Pesquisa do Estado de São Paulo (Sao Paulo, BR)
GRANT_NUMBER: 12/51420-7
Source: Self-asserted source
Cristian Cortez

Estrutura e função da principal molécula de superfície de formas metacíclicas de Trypanosoma cruzi com propriedade adesiva e sinalizadora envolvida na invasão celular e infecção oral

2008 to 2013 | Grant
Conselho Nacional de Desenvolvimento Científico e Tecnológico (Sao Paulo, BR)
Source: Self-asserted source
Cristian Cortez

Works (32)

Correction: Vicencio et al. Transcriptional Signatures and Network-Based Approaches Identified Master Regulators Transcription Factors Involved in Experimental Periodontitis Pathogenesis. <i>Int. J. Mol. Sci.</i> 2023, <i>24</i>, 14835

International Journal of Molecular Sciences
2024-01 | Journal article | Author
DOI: 10.3390/ijms25031671
Contributors: Emiliano Vicencio; Josefa Nuñez-Belmar; Juan P. Cardenas; Bastian I. Cortés; Alberto J.M. Martin; Vinicius Maracaja-Coutinho; Adolfo Rojas-Hidalgo; Emilio A. Cafferata; Luis Gustavo Gonzalez Osuna ; Rolando Vernal et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

Influence of Topography and Composition of Commercial Titanium Dental Implants on Cell Adhesion of Human Gingiva-Derived Mesenchymal Stem Cells: An In Vitro Study

International Journal of Molecular Sciences
2023-11-24 | Journal article
DOI: 10.3390/ijms242316686
Contributors: Vanessa Campos-Bijit; Nicolás Cohn Inostroza; Rocío Orellana; Alejandro Rivera; Alfredo Von Marttens; Cristian Cortez; Cristian Covarrubias
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Crossref
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Transcriptional Signatures and Network-Based Approaches Identified Master Regulators Transcription Factors Involved in Experimental Periodontitis Pathogenesis

International Journal of Molecular Sciences
2023-10 | Journal article | Author
DOI: 10.3390/ijms241914835
Contributors: Emiliano Vicencio; Josefa Nuñez-Belmar; Juan P. Cardenas; Bastian I. Cortés; Alberto J.M. Martin; Vinicius Maracaja-Coutinho; Adolfo Rojas-Hidalgo; Emilio A. Cafferata; Luis Gustavo Gonzalez Osuna ; Rolando Vernal et al.
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Multidisciplinary Digital Publishing Institute
grade
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Phylogenomic analysis of the <i>Porphyromonas gingivalis - Porphyromonas gulae</i> duo: approaches to the origin of periodontitis.

Frontiers in microbiology
2023-07-19 | Journal article
DOI: 10.3389/fmicb.2023.1226166
PMID: 37538845
PMC: PMC10394638
Contributors: Morales-Olavarría M; Josefa Nuñez-Belmar; González D; Vicencio E; Rivas-Pardo JA; Cortez C; Cárdenas JP
Source: Self-asserted source
Cristian Cortez

Contribution of −Omics Technologies in the Study of Porphyromonas gingivalis during Periodontitis Pathogenesis: A Minireview

International Journal of Molecular Sciences
2022-12-30 | Journal article
DOI: 10.3390/ijms24010620
Contributors: Josefa Nuñez-Belmar; Mauricio Morales-Olavarria; Emiliano Vicencio; Rolando Vernal; Juan P. Cárdenas; Cristian Cortez
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Crossref
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Senescent CD4+CD28− T Lymphocytes as a Potential Driver of Th17/Treg Imbalance and Alveolar Bone Resorption during Periodontitis

International Journal of Molecular Sciences
2022-02-25 | Journal article
DOI: 10.3390/ijms23052543
Contributors: Luis González-Osuna; Alfredo Sierra-Cristancho; Emilio A. Cafferata; Samanta Melgar-Rodríguez; Carolina Rojas; Paola Carvajal; Cristian Cortez; Rolando Vernal
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Crossref
grade
Preferred source (of 2)‎

Levels of low-molecular-weight hyaluronan in periodontitis-treated patients and its immunostimulatory effects on CD4+ T lymphocytes

Clinical Oral Investigations
2021-08-05 | Journal article
DOI: 10.1007/s00784-021-03808-9
Contributors: Francisca Castillo; Gustavo Monasterio; Juan Pablo Ibarra; José Guevara; Emilio A. Cafferata; Emiliano Vicencio; Cristian Cortez; Paola Carvajal; Rolando Vernal
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Crossref

Boldine inhibits the alveolar bone resorption during ligature‐induced periodontitis by modulating the Th17/Treg imbalance

Journal of Periodontology
2021-01 | Journal article
DOI: 10.1002/JPER.20-0055
Contributors: Emilio A. Cafferata; Sebastián Castro‐Saavedra; Gonzalo Fuentes‐Barros; Samanta Melgar‐Rodríguez; Felipe Rivera; Paola Carvajal; Marcela Hernández; Bastián I. Cortés; Cristian Cortez; Bruce K. Cassels et al.
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Crossref

Interleukin‐35 inhibits alveolar bone resorption by modulating the Th17/Treg imbalance during periodontitis

Journal of Clinical Periodontology
2020-06 | Journal article
DOI: 10.1111/jcpe.13282
Contributors: Emilio A. Cafferata; Claudia Terraza‐Aguirre; Romina Barrera; Nicolás Faúndez; Nicolás González; Carolina Rojas; Samanta Melgar‐Rodríguez; Marcela Hernández; Paola Carvajal; Cristian Cortez et al.
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Crossref

Aggregatibacter Actinomycetemcomitans Induces Autophagy in Human Junctional Epithelium Keratinocytes

Cells
2020-05-14 | Journal article
DOI: 10.3390/cells9051221
Part of ISSN: 2073-4409
Source: Self-asserted source
Cristian Cortez

Boldine inhibits the alveolar bone resorption during ligature-induced periodontitis by modulating the Th17/Treg imbalance

journal Periodontology
2020-04 | Journal article
Source: Self-asserted source
Cristian Cortez

Interleukin-35 inhibits alveolar bone resorption by modulating the Th17/Treg imbalance during periodontitis.

Journal Clinical Periodontololy
2020-03-11 | Journal article
Source: Self-asserted source
Cristian Cortez

Inhibitory effect of serotype a of A. actinomycetemcomitans on the increased destructive potential of serotype b

Oral Diseases
2019-11-18 | Journal article
Source: Self-asserted source
Cristian Cortez

Engineering a single-chain antibody against Trypanosoma cruzi metacyclic trypomastigotes to block cell invasion

Plos One
2019-10-16 | Journal article
Source: Self-asserted source
Cristian Cortez

ATP6V0d2 controls Leishmania parasitophorous vacuole biogenesis via cholesterol homeostasis

PLOS Pathogens
2019-06-14 | Journal article
DOI: 10.1371/journal.ppat.1007834
Part of ISSN: 1553-7374
Source: Self-asserted source
Cristian Cortez
grade
Preferred source (of 2)‎

Signal peptide recognition in Trypanosoma cruzi GP82 adhesin relies on its localization at protein N-terminus

Scientific Reports
2019-05-13 | Journal article
DOI: 10.1038/s41598-019-43743-0
Part of ISSN: 2045-2322
Source: Self-asserted source
Cristian Cortez

IL ‐22–expressing CD 4 + AhR + T lymphocytes are associated with RANKL ‐mediated alveolar bone resorption during experimental periodontitis

Journal of Periodontal Research
2019-04-29 | Journal article
DOI: 10.1111/jre.12654
Part of ISSN: 0022-3484
Part of ISSN: 1600-0765
Source: Self-asserted source
Cristian Cortez
grade
Preferred source (of 2)‎

Network approach identifies Pacer as an autophagy protein involved in ALS pathogenesis

Molecular Neurodegeneration
2019-03-27 | Journal article
DOI: 10.1186/s13024-019-0313-9
Part of ISSN: 1750-1326
Source: Self-asserted source
Cristian Cortez

Gadolinium Chloride Rescues Niemann–Pick Type C Liver Damage

International Journal of Molecular Sciences
2018-11 | Journal article | Author
DOI: 10.3390/ijms19113599
Contributors: ANDRES KLEIN; Juan Esteban Oyarzún; Cristian Cortez; Silvana Zanlungo
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Multidisciplinary Digital Publishing Institute

Surface Molecules Released by Trypanosoma cruzi Metacyclic Forms Downregulate Host Cell Invasion.

PLoS Neglected Tropical Diseases. 2016 Aug 2;10(8):e0004883.
2016-07-02 | Journal article
Source: Self-asserted source
Cristian Cortez

Lysosome biogenesis/scattering increases host cell susceptibility to invasion by Trypanosoma cruzi metacyclic forms and resistance to tissue culture trypomastigotes.

Cellular Microbiology. 2016 May;18(5):748-60. doi: 10.1111/cmi.12548.
2016-05-18 | Journal article
Source: Self-asserted source
Cristian Cortez

Unique behavior of Trypanosoma cruzi mevalonate kinase: A conserved glycosomal enzyme involved in host cell invasion and signaling.

Scientific Reports. 2016 Apr 26;6:24610. doi: 10.1038/srep24610.
2016-04-26 | Journal article
Source: Self-asserted source
Cristian Cortez

Host cell invasion and oral infection by Trypanosoma cruzi strains of genetic groups TcI and TcIV from chagasic patients.

Parasites and Vectors. 2016 Apr 1;9:189. doi: 10.1186/s13071-016-1455-z.
2016-04-01 | Journal article
Source: Self-asserted source
Cristian Cortez

Molecular Characterization of a Novel Family of Trypanosoma cruzi Surface Membrane Proteins (TcSMP) Involved in Mammalian Host Cell Invasion.

PLoS Neglected Tropical Diseases. 2015 Nov 13;9(11):e0004216. doi: 10.1371/journal.pntd.0004216.
2015-11-13 | Journal article
Source: Self-asserted source
Cristian Cortez

Fibronectin-degrading activity of Trypanosoma cruzi cysteine proteinase plays a role in host cell invasion.

Infection and Immunity. 2014 Dec;82(12):5166-74. doi: 10.1128/IAI.02022-14.
2014-12-01 | Journal article
Source: Self-asserted source
Cristian Cortez

The gp82 surface molecule of Trypanosoma cruzi metacyclic forms.

Proteins and Proteomics of Leishmania and Trypanosoma
2014-10-01 | Book chapter
Source: Self-asserted source
Cristian Cortez

Molecular characterization of Trypanosoma cruzi SAP proteins with host-cell lysosome exocytosis-inducing activity required for parasite invasion.

PLoS One. 2013 Dec 31;8(12):e83864. doi: 10.1371/journal.pone.0083864.
2013-12-31 | Journal article
Source: Self-asserted source
Cristian Cortez

Cell signaling during Trypanosoma cruzi invasion.

Frontiers Immunology. 2012 Nov 28;3:361. doi: 10.3389/fimmu.2012.00361
2012-11-01 | Journal article
Source: Self-asserted source
Cristian Cortez

Structural basis of the interaction of a Trypanosoma cruzi surface molecule implicated in oral infection with host cells and gastric mucin.

PLoS One. 2012;7(7):e42153. doi: 10.1371/journal.pone.0042153.
2012-07-01 | Journal article
Source: Self-asserted source
Cristian Cortez

Differential infectivity by the oral route of Trypanosoma cruzi lineages derived from Y strain.

PLoS Neglected Tropical Diseases. 2012;6(10):e1804. doi: 10.1371/journal.pntd.0001804.
2012-06-01 | Journal article
Source: Self-asserted source
Cristian Cortez

Mammalian cell invasion by closely related Trypanosoma species T. dionisii and T. cruzi.

Acta Tropical. 2012 Feb;121(2):141-7. doi: 10.1016/j.actatropica.2011.10.017.
2012-02-01 | Journal article
Source: Self-asserted source
Cristian Cortez

Characterization of the infective properties of a new genetic group of Trypanosoma cruzi associated with bats.

Acta Tropical. 2011 Dec;120(3):231-7. doi: 10.1016/j.actatropica.2011.09.001.
2011-12-01 | Journal article
Source: Self-asserted source
Cristian Cortez
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