Personal information

Activities

Employment (2)

Icahn School of Medicine at Mount Sinai: New York, NY, US

2018-07-01 to present | Assistant Professor (Genetics and Genomic Sciences)
Employment
Source: Self-asserted source
Aleksandra Wroblewska

Icahn School of Medicine at Mount Sinai: New York, NY, US

2013-10-14 to 2018-06-30 | Postdoctoral Fellow (Genetics and Genomic Sciences)
Employment
Source: Self-asserted source
Aleksandra Wroblewska

Education and qualifications (1)

University of Amsterdam: Amsterdam, Noord-Holland, NL

2009-02-01 to 2013-05-25 | PhD student
Qualification
Source: Self-asserted source
Aleksandra Wroblewska

Works (12)

SIRT6 haploinsufficiency induces BRAF<sup>V600E</sup>melanoma cell resistance to MAPK inhibitors via IGF signalling

Nature Communications
2018 | Journal article
EID:

2-s2.0-85052220499

Contributors: Strub, T.; Ghiraldini, F.G.; Carcamo, S.; Li, M.; Wroblewska, A.; Singh, R.; Goldberg, M.S.; Hasson, D.; Wang, Z.; Gallagher, S.J. et al.
Source: Self-asserted source
Aleksandra Wroblewska via Scopus - Elsevier

Protein Barcodes Enable High-Dimensional Single-Cell CRISPR Screens

Cell
2018-11 | Journal article
Part of ISSN: 0092-8674
Source: Self-asserted source
Aleksandra Wroblewska

Enhanced uptake of blood coagulation factor VIII containing immune complexes by antigen presenting cells

Journal of Thrombosis and Haemostasis
2017 | Journal article
EID:

2-s2.0-85012235850

Contributors: Hartholt, R.B.; Wroblewska, A.; Herczenik, E.; Peyron, I.; ten Brinke, A.; Rispens, T.; Nolte, M.A.; Slot, E.; Claassens, J.W.; Nimmerjahn, F. et al.
Source: Self-asserted source
Aleksandra Wroblewska via Scopus - Elsevier

Mapping the effects of drugs on the immune system

Nature Biotechnology
2016 | Journal article
EID:

2-s2.0-84953775211

Contributors: Kidd, B.A.; Wroblewska, A.; Boland, M.R.; Agudo, J.; Merad, M.; Tatonetti, N.P.; Brown, B.D.; Dudley, J.T.
Source: Self-asserted source
Aleksandra Wroblewska via Scopus - Elsevier

Rational design of small molecules targeting the C2 domain of coagulation factor VIII

Blood
2014 | Journal article
EID:

2-s2.0-84894447457

Contributors: Nicolaes, G.A.F.; Kulharia, M.; Voorberg, J.; Kaijen, P.H.; Wroblewska, A.; Wielders, S.; Schrijver, R.; Sperandio, O.; Villoutreix, B.O.
Source: Self-asserted source
Aleksandra Wroblewska via Scopus - Elsevier

Dangerous liaisons: How the immune system deals with factor VIII

Journal of Thrombosis and Haemostasis
2013 | Journal article
EID:

2-s2.0-84873025423

Contributors: Wroblewska, A.; Reipert, B.M.; Pratt, K.P.; Voorberg, J.
Source: Self-asserted source
Aleksandra Wroblewska via Scopus - Elsevier

Factor VIII C1 domain spikes 2092-2093 and 2158-2159 comprise regions that modulate cofactor function and cellular uptake

Journal of Biological Chemistry
2013 | Journal article
EID:

2-s2.0-84885630201

Contributors: Bloem, E.; Van Den Biggelaar, M.; Wroblewska, A.; Voorberg, J.; Faber, J.H.; Kjalke, M.; Stennicke, H.R.; Mertens, K.; Meijer, A.B.
Source: Self-asserted source
Aleksandra Wroblewska via Scopus - Elsevier

Limited promiscuity of HLA-DRB1 presented peptides derived of blood coagulation factor VIII

PLoS ONE
2013 | Journal article
EID:

2-s2.0-84893526037

Contributors: Van Haren, S.D.; Wroblewska, A.; Herczenik, E.; Kaijen, P.H.; Ruminska, A.; Ten Brinke, A.; Meijer, A.B.; Voorberg, J.
Source: Self-asserted source
Aleksandra Wroblewska via Scopus - Elsevier

Modification of an exposed loop in the C1 domain reduces immune responses to factor VIII in hemophilia A mice

Blood
2012 | Journal article
EID:

2-s2.0-84861896973

Contributors: Wroblewska, A.; Van Haren, S.D.; Herczenik, E.; Kaijen, P.; Ruminska, A.; Jin, S.-Y.; Zheng, X.L.; Van Den Biggelaar, M.; Ten Brinke, A.; Meijer, A.B. et al.
Source: Self-asserted source
Aleksandra Wroblewska via Scopus - Elsevier

Reply

Journal of Allergy and Clinical Immunology
2012 | Journal article
EID:

2-s2.0-84859158261

Contributors: Herczenik, E.; Van Haren, S.D.; Wroblewska, A.; Kaijen, P.; Van Den Biggelaar, M.; Meijer, A.B.; Ten Brinke, A.; Voorberg, J.
Source: Self-asserted source
Aleksandra Wroblewska via Scopus - Elsevier

Requirements for immune recognition and processing of factor VIII by antigen-presenting cells

Blood Reviews
2012 | Journal article
EID:

2-s2.0-83355173939

Contributors: Van Haren, S.D.; Wroblewska, A.; Fischer, K.; Voorberg, J.; Herczenik, E.
Source: Self-asserted source
Aleksandra Wroblewska via Scopus - Elsevier

Uptake of blood coagulation factor VIII by dendritic cells is mediated via its C1 domain

Journal of Allergy and Clinical Immunology
2012 | Journal article
EID:

2-s2.0-84856486915

Contributors: Herczenik, E.; Van Haren, S.D.; Wroblewska, A.; Kaijen, P.; Van Den Biggelaar, M.; Meijer, A.B.; Martinez-Pomares, L.; Ten Brinke, A.; Voorberg, J.
Source: Self-asserted source
Aleksandra Wroblewska via Scopus - Elsevier

Peer review (1 review for 1 publication/grant)

Review activity for STAR protocols. (1)