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Scopus Author ID: 57077971100
SciProfiles: 2412576

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Brazil

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Employment (2)

Universidade Estadual de Campinas (UNICAMP): Campinas, BR

2023-10-01 to present | Post-Doctoral Researcher (Instituto de Química)
Employment
Source: Self-asserted source
Marina Themoteo Varela

Universidade Federal de São Paulo: Diadema, BR

2022-11-01 to 2023-09-30 | Post-Doctoral Researcher (Pharmaceutical Sciences)
Employment
Source: Self-asserted source
Marina Themoteo Varela

Education and qualifications (4)

Universidade Federal de São Paulo: São Paulo, BR

2018-06-01 to 2022-09-30 | PhD (Medicine)
Education
Source: Self-asserted source
Marina Themoteo Varela

University of Dundee School of Life Sciences: Dundee, Dundee, GB

2020-03-01 to 2021-02-28 | PhD Student (Biological Chemistry and Drug Discovery)
Qualification
Source: Self-asserted source
Marina Themoteo Varela

Universidade Federal de São Paulo: Diadema, BR

2016-04-01 to 2018-03-28 | Master Degree (Pharmaceutical Sciences)
Education
Source: Self-asserted source
Marina Themoteo Varela

Universidade Federal de São Paulo: Diadema, BR

2011-03-28 to 2016-03-10 | Bachelor (Pharmaceutical Sciences)
Education
Source: Self-asserted source
Marina Themoteo Varela

Professional activities (1)

Universidade Federal de São Paulo: Diadema, São Paulo, BR

2018-12-12 | Menção Honrosa - Jovem Pesquisador
Distinction
Source: Self-asserted source
Marina Themoteo Varela

Works (19)

Investigation of Structure–Activity Relationships for Benzoyl and Cinnamoyl Piperazine/Piperidine Amides as Tyrosinase Inhibitors

ACS Omega
2023-11-21 | Journal article
DOI: 10.1021/acsomega.3c06977
Part of ISSN: 2470-1343
Part of ISSN: 2470-1343
Contributors: Marina T. Varela; Erica V. de Castro Levatti; Tempone AG; João Paulo dos Santos Fernandes
Source: Self-asserted source
Marina Themoteo Varela

Piperazine amides with desirable solubility, physicochemical and drug-like properties: Synthesis and evaluation of the anti-Trypanosoma cruzi activity

Saudi Pharmaceutical Journal
2023-07 | Journal article
DOI: 10.1016/j.jsps.2023.05.014
Contributors: Marina T. Varela; Maiara Romanelli; Maiara Amaral; Andre G. Tempone; João Paulo S. Fernandes
Source: check_circle
Crossref

Synthetic Analogues of Gibbilimbol B Induce Bioenergetic Damage and Calcium Imbalance in Trypanosoma cruzi

Life
2023-02-28 | Journal article
DOI: 10.3390/life13030663
Contributors: Maiara Amaral; Marina T. Varela; Ravi Kant; Myron Christodoulides; João Paulo S. Fernandes; Andre G. Tempone
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Esterification of p-Coumaric Acid Improves the Control over Melanoma Cell Growth

Biomedicines
2023-01-12 | Journal article
DOI: 10.3390/biomedicines11010196
Contributors: Marina Themoteo Varela
Source: Self-asserted source
Marina Themoteo Varela
grade
Preferred source (of 3)‎

Optimization of physicochemical properties is a strategy to improve drug-likeness associated with activity: Novel active and selective compounds against Trypanosoma cruzi

European Journal of Pharmaceutical Sciences
2022-04 | Journal article
DOI: 10.1016/j.ejps.2021.106114
Part of ISSN: 0928-0987
Source: Self-asserted source
Marina Themoteo Varela

Bioisosteric modification on benzylidene‐carbonyl compounds improved the drug‐likeness and maintained the antifungal activity against Sporothrix brasiliensis

Chemical Biology & Drug Design
2022-03 | Journal article
DOI: 10.1111/cbdd.13994
Part of ISSN: 1747-0277
Part of ISSN: 1747-0285
Source: Self-asserted source
Marina Themoteo Varela

Novel potent (dihydro)benzofuranyl piperazines as human histamine receptor ligands – Functional characterization and modeling studies on H<inf>3</inf> and H<inf>4</inf> receptors

Bioorganic and Medicinal Chemistry
2021 | Journal article
DOI: 10.1016/j.bmc.2020.115924
EID:

2-s2.0-85097780585

Part of ISSN: 14643391 09680896
Contributors: Corrêa, M.F.; Balico-Silva, A.L.; Kiss, D.J.; Fernandes, G.A.B.; Maraschin, J.C.; Parreiras-e-Silva, L.T.; Varela, M.T.; Simões, S.C.; Bouvier, M.; Keserű, G.M. et al.
Source: Self-asserted source
Marina Themoteo Varela via Scopus - Elsevier

Benzylidene-carbonyl compounds are active against itraconazole-susceptible and itraconazole-resistant Sporothrix brasiliensis

Folia Microbiologica
2020 | Journal article
DOI: 10.1007/s12223-020-00814-4
EID:

2-s2.0-85089731569

Part of ISSN: 18749356 00155632
Contributors: Waller, S.B.; Cleff, M.B.; Ripoll, M.K.; Meireles, M.C.A.; Varela, M.T.; Fernandes, J.P.S.
Source: Self-asserted source
Marina Themoteo Varela via Scopus - Elsevier

Coumaric acid derivatives as tyrosinase inhibitors: Efficacy studies through in silico, in vitro and ex vivo approaches

Bioorganic Chemistry
2020 | Journal article
DOI: 10.1016/j.bioorg.2020.104108
EID:

2-s2.0-85088954941

Part of ISSN: 10902120 00452068
Contributors: Varela, M.T.; Ferrarini, M.; Mercaldi, V.G.; Sufi, B.D.S.; Padovani, G.; Nazato, L.I.S.; Fernandes, J.P.S.
Source: Self-asserted source
Marina Themoteo Varela via Scopus - Elsevier

Improving the drug-likeness of inspiring natural products - evaluation of the antiparasitic activity against Trypanosoma cruzi through semi-synthetic and simplified analogues of licarin A

Scientific Reports
2020 | Journal article
DOI: 10.1038/s41598-020-62352-w
EID:

2-s2.0-85082589194

Part of ISSN: 20452322
Contributors: Morais, T.R.; Conserva, G.A.A.; Varela, M.T.; Costa-Silva, T.A.; Thevenard, F.; Ponci, V.; Fortuna, A.; Falcão, A.C.; Tempone, A.G.; Fernandes, J.P.S. et al.
Source: Self-asserted source
Marina Themoteo Varela via Scopus - Elsevier

Profiling of LINS01 compounds at human dopamine D<inf>2</inf> and D<inf>3</inf> receptors

Journal of Chemical Sciences
2020 | Journal article
DOI: 10.1007/s12039-019-1694-6
EID:

2-s2.0-85076786444

Part of ISSN: 09737103 09743626
Contributors: Corrêa, M.F.; Reiner, D.; Fernandes, G.A.B.; Varela, M.T.; Aranha, C.M.S.Q.; Stark, H.; Fernandes, J.P.S.
Source: Self-asserted source
Marina Themoteo Varela via Scopus - Elsevier

Coumaric acid analogues inhibit growth and melanin biosynthesis in Cryptococcus neoformans and potentialize amphotericin B antifungal activity

European Journal of Pharmaceutical Sciences
2020-10 | Journal article
DOI: 10.1016/j.ejps.2020.105473
Part of ISSN: 0928-0987
Source: Self-asserted source
Marina Themoteo Varela
grade
Preferred source (of 4)‎

Evaluation of the antitrypanosoma activity and SAR study of novel LINS03 derivatives

Bioorganic Chemistry
2019-08 | Journal article
DOI: 10.1016/j.bioorg.2019.102996
Part of ISSN: 0045-2068
Source: Self-asserted source
Marina Themoteo Varela
grade
Preferred source (of 2)‎

Pyrazinoates as antiparasitic agents against Trypanosoma cruzi

Archiv der Pharmazie
2018-11 | Journal article
DOI: 10.1002/ardp.201800190
Part of ISSN: 0365-6233
Source: Self-asserted source
Marina Themoteo Varela
grade
Preferred source (of 2)‎

Antiparasitic activity of new gibbilimbol analogues and SAR analysis through efficiency and statistical methods

European Journal of Pharmaceutical Sciences
2018-09 | Journal article
DOI: 10.1016/j.ejps.2018.06.023
Part of ISSN: 0928-0987
Source: Self-asserted source
Marina Themoteo Varela
grade
Preferred source (of 2)‎

Natural Products: Key Prototypes to Drug Discovery Against Neglected Diseases Caused by Trypanosomatids

Current Medicinal Chemistry
2018-05-01 | Journal article
DOI: 10.2174/0929867325666180501102450
Part of ISSN: 0929-8673
Source: Self-asserted source
Marina Themoteo Varela
grade
Preferred source (of 2)‎

New alkenyl derivative from Piper malacophyllum and analogues: Antiparasitic activity against Trypanosoma cruzi and Leishmania infantum

Chemical Biology & Drug Design
2017-11 | Journal article
DOI: 10.1111/cbdd.12986
Part of ISSN: 1747-0277
Source: Self-asserted source
Marina Themoteo Varela
grade
Preferred source (of 2)‎

1-[(2,3-Dihydro-1-benzofuran-2-yl) methyl]piperazines as novel anti-inflammatory compounds: Synthesis and evaluation on H3R/H4R

Chemical Biology & Drug Design
2017-08 | Journal article
DOI: 10.1111/cbdd.12947
Part of ISSN: 1747-0277
Source: Self-asserted source
Marina Themoteo Varela
grade
Preferred source (of 2)‎

Gibbilimbol analogues as antiparasitic agents—Synthesis and biological activity against Trypanosoma cruzi and Leishmania (L.) infantum

Bioorganic & Medicinal Chemistry Letters
2016-02 | Journal article
DOI: 10.1016/j.bmcl.2016.01.040
Part of ISSN: 0960-894X
Source: Self-asserted source
Marina Themoteo Varela
grade
Preferred source (of 2)‎
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