Gary Sharples

ORCID iD
orcid.org/0000-0003-2495-0062
  • Country
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United Kingdom

Sources:
Gary Sharples (2016-02-04)

  • Keywords
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genetic recombination,

Sources:
Gary Sharples (2016-02-04)

DNA repair,

Sources:
Gary Sharples (2016-02-04)

bacterial and bacteriophage evolution,

Sources:
Gary Sharples (2016-02-04)

DNA-protein interactions,

Sources:
Gary Sharples (2016-02-04)

antibacterial agents

Sources:
Gary Sharples (2016-02-04)

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  • Other IDs
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ResearcherID: B-8638-2016

Sources:
Clarivate Analytics (2016-02-04)

Biography

My research focusses on the molecular mechanisms of bacterial and bacteriophage genome rearrangements and their impact on the evolution of microbial pathogens. I have particular interest in Holliday junction processing systems including, RuvABC, RecG, RusA, Rap and other phage-encoded DNA binding proteins. I also have wide-ranging interests at the chemistry-biology interface, particularly in the development of novel antimicrobials to combat drug resistance. These include investigating the antibacterial properties and mode of action of nanoparticles, metal oxides and other modified surfaces, metal chelating agents, peptides, peptoids and other small molecules.
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