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Scopus Author ID: 57189263705

Countries

Brazil

Biography

Postdoctoral fellow at the Organic Micromolecules Mass Spectrometry Center (CEMMO) of the Faculty of Pharmaceutical Sciences of Ribeirão Preto (FCFRP-USP). PhD in Science (in the Toxicology Program - FCFRP-USP/2016), with experience in the development and validation of analytical methods using HPLC and in Mass Spectrometry for analysis of impurities in pharmaceutical products and for chemical, toxicological and biokinetic evaluations of natural and synthetic products in drug development. He was professor of Quality Control of Pharmaceutical Products and Cosmetics at FCFRP-USP (2020-2022) and professor of Biological Quality Control and Toxicology at the School of Pharmacy of the Federal University of Ouro Preto (UFOP) (2010-2012). Master's degree in Pharmaceutical Sciences (UFOP/ 2011) with experience in HPLC, pharmacokinetics and experimental chemotherapy in Chagas Disease. Industrial Pharmacist (UFOP/2007), with MBA in Pharmaceutical Industrial Management (2010), he has worked as a process validation supervisor and as a researcher in the development, validation and application of analytical methods indicative of stability for forced degradation studies for pharmaceutical industries (2016, 2017, 2021).

Activities

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Employment (5)

Universidade de São Paulo Faculdade de Ciências Farmacêuticas de Ribeirão Preto: Ribeirao Preto, SP, BR

2017-03-01 to present | Posdoctoral research (Department of Biomolecular Sciences)
Employment
Source: Self-asserted source
Rodrigo Moreira da Silva

Universidade de São Paulo Faculdade de Ciências Farmacêuticas de Ribeirão Preto: Ribeirao Preto, SP, BR

2020-03-04 to 2022-03-03 | Collaborating professor (Department of Pharmaceutical Sciences)
Employment
Source: Self-asserted source
Rodrigo Moreira da Silva

Lychnoflora (Brazil): Ribeirão Preto, BR

2016-06-01 to 2017-02-28 | Research scientist
Employment
Source: Self-asserted source
Rodrigo Moreira da Silva

Universidade Federal de Ouro Preto Escola de Farmácia: Ouro Preto, Minas Gerais, BR

2010-03-01 to 2012-02-28 | Lecturer for Toxicology, Biological Quality Control and Epidemiology (Pharmacy)
Employment
Source: Self-asserted source
Rodrigo Moreira da Silva

Bioclin: Belo Horizonte, Minas Gerais, BR

2008-01-02 to 2009-02-28 | Supervisor for validation (Quality)
Employment
Source: Self-asserted source
Rodrigo Moreira da Silva

Education and qualifications (4)

Universidade de São Paulo Faculdade de Ciências Farmacêuticas de Ribeirão Preto: Ribeirao Preto, SP, BR

2012 to 2016 | PhD (analytical toxicology)
Education
Source: Self-asserted source
Rodrigo Moreira da Silva

Universidade Federal de Ouro Preto Escola de Farmácia: Ouro Preto, Minas Gerais, BR

2009 to 2011 | Master's degree (Pharmaceutical Sciences - analytical methods, pharmacokinetics, neglected diseases)
Qualification
Source: Self-asserted source
Rodrigo Moreira da Silva

Faculdades Oswaldo Cruz: Sao Paulo, São Paulo, BR

2008 to 2009 | MBA (Pharmaceutical Industry Management)
Qualification
Source: Self-asserted source
Rodrigo Moreira da Silva

Universidade Federal de Ouro Preto Escola de Farmácia: Ouro Preto, Minas Gerais, BR

2002 to 2007 | Bachelor's degree, Pharmacy (Industry)
Qualification
Source: Self-asserted source
Rodrigo Moreira da Silva

Professional activities (2)

Universidade Estadual Paulista Julio de Mesquita Filho Instituto de Química: Araraquara, São Paulo, BR

2018-11 to 2018-12 | Visiting Professor (Pharmaceutical Sciences Post Graduation Program)
Invited position
Source: Self-asserted source
Rodrigo Moreira da Silva

Universitätsklinikum Münster: Munster, Nordrhein-Westfalen, DE

2018-07 to 2018-08 | Visiting Researcher (Institut für Anorganische und Analytische Chemie)
Invited position
Source: Self-asserted source
Rodrigo Moreira da Silva

Funding (1)

IN VITRO BIODISTRIBUTION OF COLLAGEN PEPTIDES IN SKIN MODELS: FROM ABSORPTION UNDERSTANDING TO TISSUE IMAGES GENERATION BY MASS SPECTROMETRY

2021-12 to 2025-01 | Contract
JBS (São Paulo, São Paulo, BR)
Source: Self-asserted source
Rodrigo Moreira da Silva

Works (29)

Characterization of the fragmentation mechanisms in electrospray ionization tandem mass spectrometry of chloroquinoline derivatives with larvicidal activity against Aedes aegypti

Rapid Communications in Mass Spectrometry
2024-06-30 | Journal article
DOI: 10.1002/rcm.9739
Contributors: Rodrigo Moreira da Silva; Jéssica Guastalli Barbieri; Valter Eduardo Murie; Maíra Rosato Silveira Silvério; Rafael Augusto Soldi; Lorena Carneiro Albernaz; Laila Salmen Espindola; Paulo Cézar Vieira; Giuliano Cesar Clososki; Ricardo Vessecchi et al.
Source: check_circle
Crossref

Lychnophora ericoides Mart. (Brazilian arnica) ethanol extract accelerates the skin wound healing process: Evidence for its mechanism of action

Phytomedicine
2023-10 | Journal article
DOI: 10.1016/j.phymed.2023.155000
Contributors: Barbhara Mota Marinho; Victor Hugo Dantas Guimarães; Daniel Silva Moraes; Guilherme Henrique Mendes Ribeiro; Rodrigo Moreira da Silva; Norberto Peporine Lopes; André Luiz Sena Guimarães; Alfredo Maurício Batista de Paula; Sérgio Henrique Sousa Santos
Source: check_circle
Crossref

Effect of Roux‐En‐Y Gastric Bypass in the Pharmacokinetics of (<i>R</i>)‐Carvedilol and (<i>S</i>)‐Carvedilol

The Journal of Clinical Pharmacology
2023-07 | Journal article
DOI: 10.1002/jcph.2221
Part of ISSN: 0091-2700
Part of ISSN: 1552-4604
Contributors: Priscila Akemi Yamamoto; Rodrigo Cristofoletti; Valvanera Vozmediano; Cristiane Masetto de Gaitani; Rodrigo Moreira da Silva; Rafael Kemp; Ajith Kumar Sankarankutty; Wilson Salgado Junior; Jose Sebastião dos Santos; Natalia Valadares de Moraes
Source: Self-asserted source
Rodrigo Moreira da Silva

Sex‐ and age‐specific respiratory alterations induced by prenatal exposure to the cannabinoid receptor agonist WIN 55,212‐2 in rats

British Journal of Pharmacology
2023-07 | Journal article
DOI: 10.1111/bph.16044
Part of ISSN: 0007-1188
Part of ISSN: 1476-5381
Contributors: Luis Gustavo A. Patrone; Gustavo D. Ferrari; Rodrigo Moreira da Silva; Luciane C. Alberici; Norberto Peporine Lopes; Angelita M. Stabile; Wilfried Klein; Kênia C. Bícego; Luciane H. Gargaglioni
Source: Self-asserted source
Rodrigo Moreira da Silva

Oxidation Products from the Neolignan Licarin A by Biomimetic Reactions and Assessment of in vivo Acute Toxicity

Planta Medica
2023-03-08 | Journal article
DOI: 10.1055/a-2009-0732
Part of ISSN: 0032-0943
Part of ISSN: 1439-0221
Contributors: Juliana Neves de Paula e Souza; Rodrigo Moreira da Silva; Simone Silveira Fortes; Anderson Rodrigo Moraes de Oliveira; Leandro De Santis Ferreira; Ricardo Vessecchi; Norberto Peporine Lopes; Silva, DB
Source: Self-asserted source
Rodrigo Moreira da Silva

Chemometric optimization of salting-out assisted liquid–liquid extraction (SALLE) combined with LC-MS/MS for the analysis of carvedilol enantiomers in human plasma: Application to clinical pharmacokinetics

Journal of Chromatography B
2022-08 | Journal article
DOI: 10.1016/j.jchromb.2022.123338
Part of ISSN: 1570-0232
Contributors: Rodrigo Moreira da Silva; Marcella Pavan; Priscila Yamamoto; Rodrigo Moreira da Silva; Wilson Salgado Junior; José dos Santos; Rafael Kemp; Ajith Sankarankutty; Natália de Moraes; Cristiane de Gaitani
Source: Self-asserted source
Rodrigo Moreira da Silva

Enhancing untargeted metabolomics using metadata-based source annotation

Nature Biotechnology
2022-07-07 | Journal article | Author
DOI: 10.1038/s41587-022-01368-1
Part of ISSN: 1087-0156
Part of ISSN: 1546-1696
Contributors: Julia M. Gauglitz; Kiana A. West; Wout Bittremieux; Candace L. Williams; Kelly C Weldon; Morgan Panitchpakdi; Francesca Di Ottavio; Christine M. Aceves; Elizabeth Brown; Nicole C. Sikora et al.
Source: Self-asserted source
Rodrigo Moreira da Silva

In vitro-in vivo correlation of the chiral pesticide prothioconazole after interaction with human CYP450 enzymes

Food and Chemical Toxicology
2022-05 | Journal article
DOI: 10.1016/j.fct.2022.112947
Part of ISSN: 0278-6915
Source: Self-asserted source
Rodrigo Moreira da Silva

Topical gel containing phenolic-rich extract from Ipomoea pes-capre leaf (Convolvulaceae) has anti-inflammatory, wound healing, and antiophidic properties

Biomedicine &amp; Pharmacotherapy
2022-05 | Journal article
DOI: 10.1016/j.biopha.2022.112921
Part of ISSN: 0753-3322
Source: Self-asserted source
Rodrigo Moreira da Silva

Sphingolipids signature in plasma and tissue as diagnostic and prognostic tools in oral squamous cell carcinoma

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
2022-01 | Journal article
DOI: 10.1016/j.bbalip.2021.159057
Part of ISSN: 1388-1981
Source: Self-asserted source
Rodrigo Moreira da Silva

IN VITRO METABOLISM OF COPALIC AND KAURENOIC ACIDS IN RAT AND HUMAN LIVER MICROSOMES

Química Nova
2021 | Journal article
DOI: 10.21577/0100-4042.20170724
Part of ISSN: 0100-4042
Part of ISSN: 1678-7064
Source: Self-asserted source
Rodrigo Moreira da Silva

In vitro enantioselective inhibition of the main human CYP450 enzymes involved in drug metabolism by the chiral pesticide tebuconazole

Toxicology Letters
2021-10 | Journal article
DOI: 10.1016/j.toxlet.2021.08.006
Contributors: Maísa Daniela Habenschus; Daniel Blascke Carrão; Nayara Cristina Perez de Albuquerque; Icaro Salgado Perovani; Rodrigo Moreira da Silva; Viviani Nardini; Norberto Peporine Lopes; Luís Gustavo Dias; Anderson Rodrigo Moraes de Oliveira
Source: check_circle
Crossref

Enantioselective inhibition of human CYP2C19 by the chiral pesticide ethofumesate: Prediction of pesticide-drug interactions in humans

Chemico-Biological Interactions
2021-08 | Journal article
DOI: 10.1016/j.cbi.2021.109552
Part of ISSN: 0009-2797
Contributors: Rodrigo Moreira da Silva; Icaro Salgado Perovani; Jade Lorena Mariano Bucci; Daniel Blascke Carrão; Maike Felipe Santos Barbetta; Rodrigo Moreira da Silva; Norberto Peporine Lopes; Anderson Rodrigo Moraes de Oliveira
Source: Self-asserted source
Rodrigo Moreira da Silva

Tenofovir Disoproxil Fumarate: New Chemical Developments and Encouraging in vitro Biological Results for SARS-CoV-2

Journal of the Brazilian Chemical Society
2020 | Journal article
DOI: 10.21577/0103-5053.20200106
Part of ISSN: 0103-5053
Source: Self-asserted source
Rodrigo Moreira da Silva

Risk assessment of the chiral pesticide fenamiphos in a human model: Cytochrome P450 phenotyping and inhibition studies

Food and Chemical Toxicology
2020-12 | Journal article
DOI: 10.1016/j.fct.2020.111826
Part of ISSN: 0278-6915
Contributors: Rodrigo Moreira da Silva; Nayara Cristina Perez de Albuquerque; Daniel Blascke Carrão; Maísa Daniela Habenschus; Franciele Saraiva Fonseca; Rodrigo Moreira da Silva; Norberto Peporine Lopes; Bruno Alves Rocha; Fernando Barbosa Júnior; Anderson Rodrigo Moraes de Oliveira
Source: Self-asserted source
Rodrigo Moreira da Silva

Prediction of seriniquinone-drug interactions by in vitro inhibition of human cytochrome P450 enzymes

Toxicology in Vitro
2020-06 | Journal article
DOI: 10.1016/j.tiv.2020.104820
Part of ISSN: 0887-2333
Source: Self-asserted source
Rodrigo Moreira da Silva

In Vivo Antidepressant Effect of Passiflora edulis f. flavicarpa into Cationic Nanoparticles: Improving Bioactivity and Safety

Pharmaceutics
2020-04-21 | Journal article
DOI: 10.3390/pharmaceutics12040383
Part of ISSN: 1999-4923
Source: Self-asserted source
Rodrigo Moreira da Silva

A possible solution to model nonlinearity in elimination and distributional clearances with α<inf>2</inf>-adrenergic receptor agonists: Example of the intravenous detomidine and methadone combination in sedated horses

Journal of Veterinary Pharmacology and Therapeutics
2019 | Journal article
DOI: 10.1111/jvp.12815
EID:

2-s2.0-85073922598
Contributors: Gozalo-Marcilla, M.; Moreira da Silva, R.; Pacca Loureiro Luna, S.; Rodrigues de Oliveira, A.; Werneck Fonseca, M.; Peporine Lopes, N.; Taylor, P.M.; Pelligand, L.
Source: Self-asserted source
Rodrigo Moreira da Silva via Scopus - Elsevier

An eco-friendly sample preparation procedure base on low-density solvent-based air-assisted liquid-liquid microextraction for the simultaneous determination of 21 potential endocrine disruptors in urine samples by liquid chromatography-tandem mass spectrometry

Microchemical Journal
2019 | Journal article
DOI: 10.1016/j.microc.2019.03.019
EID:

2-s2.0-85062817807
Contributors: Rocha, B.A.; de Oliveira, S.R.; da Silva, R.M.; Barcelos, G.R.M.; de Oliveira, A.R.M.; Barbosa, F.
Source: Self-asserted source
Rodrigo Moreira da Silva via Scopus - Elsevier

Characterisation of the in vivo interactions between detomidine and methadone in horses: Pharmacokinetic and pharmacodynamic modelling

Equine Veterinary Journal
2019 | Journal article
DOI: 10.1111/evj.13031
EID:

2-s2.0-85056613498
Contributors: Gozalo-Marcilla, M.; Luna, S.P.L.; Moreira da Silva, R.; Crosignani, N.; Lopes, N.P.; Taylor, P.M.; Pelligand, L.
Source: Self-asserted source
Rodrigo Moreira da Silva via Scopus - Elsevier

Characterization of Casearin X Metabolism by Rat and Human Liver Microsomes

Planta Medica
2019 | Journal article
DOI: 10.1055/a-0765-9523
EID:

2-s2.0-85062279304
Contributors: Moreira Da Silva, R.; De Gaitani, C.M.; Marques, L.M.M.; Fraige Baraco, K.; Cavalheiro, A.J.; De Moraes, L.A.B.; Lopes, N.P.; De Oliveira, A.R.M.
Source: Self-asserted source
Rodrigo Moreira da Silva via Scopus - Elsevier

In vitro inhibition of human CYP2D6 by the chiral pesticide fipronil and its metabolite fipronil sulfone: Prediction of pesticide-drug interactions

Toxicology Letters
2019 | Journal article
DOI: 10.1016/j.toxlet.2019.07.005
EID:

2-s2.0-85068783768
Contributors: Carrão, D.B.; Habenchus, M.D.; de Albuquerque, N.C.P.; da Silva, R.M.; Lopes, N.P.; de Oliveira, A.R.M.
Source: Self-asserted source
Rodrigo Moreira da Silva via Scopus - Elsevier

Myclobutanil enantioselective risk assessment in humans through in vitro CYP450 reactions: Metabolism and inhibition studies

Food and Chemical Toxicology
2019 | Journal article
DOI: 10.1016/j.fct.2019.04.009
EID:

2-s2.0-85064260021
Contributors: Fonseca, F.S.; Carrão, D.B.; de Albuquerque, N.C.P.; Nardini, V.; Dias, L.G.; da Silva, R.M.; Lopes, N.P.; de Oliveira, A.R.M.
Source: Self-asserted source
Rodrigo Moreira da Silva via Scopus - Elsevier

Determination of topiramate by capillary electrophoresis with capacitively-coupled contactless conductivity detection: A powerful tool for therapeutic monitoring in epileptic patients

Electrophoresis
2018 | Journal article
DOI: 10.1002/elps.201800046
EID:

2-s2.0-85046340770
Contributors: Ishikawa, A.A.; da Silva, R.M.; Santos, M.S.F.; da Costa, E.T.; Sakamoto, A.C.; Carrilho, E.; de Gaitani, C.M.; Garcia, C.D.
Source: Self-asserted source
Rodrigo Moreira da Silva via Scopus - Elsevier

Mass spectrometry analysis of protonated marine natural product seriniquinone

Journal of the Brazilian Chemical Society
2018 | Journal article
DOI: 10.21577/0103-5053.20180037
EID:

2-s2.0-85044455408
Contributors: Da Silva, R.M.; Guaratini, T.; Jimenez, P.C.; Fenical, W.; Costa-Lotufo, L.V.; Vessecchi, R.; Lopes, N.P.
Source: Self-asserted source
Rodrigo Moreira da Silva via Scopus - Elsevier

Pharmacokinetics and Tissue Distribution of Benznidazole after Oral Administration in Mice

Antimicrobial Agents and Chemotherapy
2017 | Journal article
DOI: 10.1128/AAC.02410-16
WOSUID: WOS:000397598800056
Contributors: Perin, Luisa; da Silva, Rodrigo Moreira; Fonseca, Katia da Silva; de Oliveira Cardoso, Jamille Mirelle; Siqueira Mathias, Fernando Augusto; Soares Reis, Levi Eduardo; Molina, Israel; Correa-Oliveira, Rodrigo; de Abreu Vieira, Paula Melo; Carneiro, Claudia Martins
Source: check_circle
Web of Science Researcher Profile Sync

Evaluation of the Intestinal Absorption Mechanism of Casearin X in Caco-2 Cells with Modified Carboxylesterase Activity

Journal of Natural Products
2016 | Journal article
DOI: 10.1021/acs.jnatprod.5b01139
EID:

2-s2.0-84967154094
Contributors: Moreira Da Silva, R.; Verjee, S.; De Gaitani, C.M.; Moraes De Oliveira, A.R.; Pires Bueno, P.C.; Cavalheiro, A.J.; Peporine Lopes, N.; Butterweck, V.
Source: Self-asserted source
Rodrigo Moreira da Silva via Scopus - Elsevier

Preclinical monitoring of drug association in experimental chemotherapy of Chagas' disease by a new HPLC-UV method

Antimicrobial Agents and Chemotherapy
2012 | Journal article
DOI: 10.1128/AAC.05785-11
EID:

2-s2.0-84861116188
Contributors: Da Silva, R.M.; Oliveira, L.T.; Barcellos, N.M.S.; De Souza, J.; De Lana, M.
Source: Self-asserted source
Rodrigo Moreira da Silva via Scopus - Elsevier

Impact of dual infections on chemotherapeutic efficacy in BALB/c mice infected with major genotypes of Trypanosoma cruzi

Antimicrobial Agents and Chemotherapy
2007 | Journal article
DOI: 10.1128/AAC.01590-06
EID:

2-s2.0-35948973496
Contributors: Martins, H.R.; Moreira Silva, R.; Valadares, H.M.S.; Toledo, M.J.O.; Veloso, V.M.; Vitelli-Avelar, D.M.; Carneiro, C.M.; Machado-Coelho, G.L.L.; Bahia, M.T.; Martins-Filho, O.A. et al.
Source: Self-asserted source
Rodrigo Moreira da Silva via Scopus - Elsevier

Peer review (3 reviews for 2 publications/grants)

Review activity for BMC cancer (1)
Review activity for Revista Brasileira de Farmacognosia. (2)
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