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Scopus Author ID: 7003368908

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Università degli Studi di Trieste: Trieste, Friuli-Venezia Giulia, IT

1971-11-01 to 1976-11-01 | Laurea in Chemistry (Chemistry)
Education
Source: Self-asserted source
Luigi XODO

Works (50 of 123)

Items per page:
Page 1 of 3

Suppression of the KRAS-NRF2 axis shifts arginine into the phosphocreatine energy system in pancreatic cancer cells

iScience
2023-12 | Journal article
DOI: 10.1016/j.isci.2023.108566
Contributors: Eros Di Giorgio; Himanshi Choudhary; Annalisa Ferino; Ylenia Cortolezzis; Emiliano Dalla; Francesca D’Este; Marina Comelli; Valentina Rapozzi; Luigi E. Xodo
Source: check_circle
Crossref

Targeted Cancer Therapy: KRAS-Specific Treatments for Pancreatic Cancer

Handbook of Chemical Biology of Nucleic Acids
2022 | Book chapter
DOI: 10.1007/978-981-16-1313-5_69-1
Part of ISBN: 9789811613135
Part of ISBN: 9789811613135
Contributors: Himanshi Choudhary; Luigi E. Xodo
Source: Self-asserted source
Luigi XODO

Bystander effect in photosensitized prostate cancer cells with a different grade of malignancy: The role of nitric oxide.

Nitric oxide : biology and chemistry
2022-08-12 | Journal article
DOI: 10.1016/j.niox.2022.08.002
PMID: 35970264
Contributors: Gani M; Xodo LE; Rapozzi V
Source: Self-asserted source
Luigi XODO

Endogenous Retroviruses (ERVs): Does RLR (RIG-I-Like Receptors)-MAVS Pathway Directly Control Senescence and Aging as a Consequence of ERV De-Repression?

Frontiers in immunology
2022-06-09 | Journal article
DOI: 10.3389/fimmu.2022.917998
PMID: 35757716
PMC: PMC9218063
Contributors: Di Giorgio E; Xodo LE
Source: Self-asserted source
Luigi XODO

Photosensitization of pancreatic cancer cells by cationic alkyl-porphyrins in free form or engrafted into POPC liposomes: The relationship between delivery mode and mechanism of cell death.

Journal of photochemistry and photobiology. B, Biology
2022-04-25 | Journal article
DOI: 10.1016/j.jphotobiol.2022.112449
PMID: 35504235
Contributors: Di Giorgio E; Ferino A; Choudhary H; Löffler PMG; Francesca D'Este; Rapozzi V; Tikhomirov A; Shchekotikhin A; Stefan Vogel; Xodo LE
Source: Self-asserted source
Luigi XODO

hnRNPA1/UP1 Unfolds KRAS G-Quadruplexes and Feeds a Regulatory Axis Controlling Gene Expression

ACS Omega
2021-12-14 | Journal article
DOI: 10.1021/acsomega.1c05538
Contributors: Annalisa Ferino; Julien Marquevielle; Himanshi Choudhary; Giorgio Cinque; Coralie Robert; Anne Bourdoncle; Raffaella Picco; Jean-Louis Mergny; Gilmar F. Salgado; Luigi E. Xodo
Source: check_circle
Crossref

Does Delayed Cord Clamping Improve Long-Term (≥4 Months) Neurodevelopment in Term Babies? A Systematic Review and a Meta-Analysis of Randomized Clinical Trials.

Frontiers in pediatrics
2021-04-12 | Journal article
DOI: 10.3389/fped.2021.651410
PMID: 33912524
PMC: PMC8071880
Contributors: Xodo S; Xodo L; Baccarini G; Lorenza DRIUL; Londero AP
Source: Self-asserted source
Luigi XODO

Antiviral Activity of the G-Quadruplex Ligand TMPyP4 against Herpes Simplex Virus-1

Viruses
2021-01 | Journal article | Author
DOI: 10.3390/v13020196
Contributors: Sara Artusi; Emanuela Ruggiero; MATTEO NADAI; Beatrice Tosoni; Rosalba Perrone; Annalisa Ferino; Irene Zanin; Luigi XODO; Louis Flamand; Sara Richter
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Effect of DNA Glycosylases OGG1 and Neil1 on Oxidized G-Rich Motif in the KRAS Promoter

International Journal of Molecular Sciences
2021-01-24 | Journal article
DOI: 10.3390/ijms22031137
Contributors: Annalisa Ferino; Luigi E. Xodo
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Quadruplex nucleic acids in KRAS targeted-cancer therapy

2020 | Book chapter
DOI: 10.1016/bs.armc.2020.04.004
Contributors: Luigi E. Xodo
Source: check_circle
Crossref

Structure of two G-quadruplexes in equilibrium in the KRAS promoter

Nucleic Acids Research
2020-09-18 | Journal article
DOI: 10.1093/nar/gkaa387
Contributors: Julien Marquevielle; Coralie Robert; Olivier Lagrabette; Mona Wahid; Anne Bourdoncle; Luigi E Xodo; Jean-Louis Mergny; Gilmar F Salgado
Source: check_circle
Crossref

Role of Poly [ADP-ribose] Polymerase 1 in Activating the Kirsten ras (KRAS) Gene in Response to Oxidative Stress

International Journal of Molecular Sciences
2020-08-28 | Journal article
DOI: 10.3390/ijms21176237
Contributors: Giorgio Cinque; Annalisa Ferino; Erik B. Pedersen; Luigi E. Xodo
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Photodynamic Therapy for ras-Driven Cancers: Targeting G-Quadruplex RNA Structures with Bifunctional Alkyl-Modified Porphyrins

Journal of Medicinal Chemistry
2020-02-13 | Journal article
DOI: 10.1021/acs.jmedchem.9b01577
Contributors: Annalisa Ferino; Giulia Nicoletto; Francesca D’Este; Sonia Zorzet; Sara Lago; Sara N. Richter; Alexander Tikhomirov; Andrey Shchekotikhin; Luigi E. Xodo
Source: check_circle
Crossref

Folate-Decorated Amphiphilic Cyclodextrins as Cell-Targeted Nanophototherapeutics

Biomacromolecules
2019-07-08 | Journal article
DOI: 10.1021/acs.biomac.9b00306
Contributors: Roberto Zagami; Valentina Rapozzi; Anna Piperno; Angela Scala; Claudia Triolo; Mariachiara Trapani; Luigi E. Xodo; Luigi Monsù Scolaro; Antonino Mazzaglia
Source: check_circle
Crossref

MicroRNA therapeutics: design of single-stranded miR-216b mimics to target KRAS in pancreatic cancer cells

RNA Biology
2018-10-03 | Journal article
DOI: 10.1080/15476286.2018.1526536
Contributors: Annalisa Ferino; Giulia Miglietta; Raffaella Picco; Stefan Vogel; Jesper Wengel; Luigi E. Xodo
Source: check_circle
Crossref

The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription

Nucleic Acids Research
2018-01-25 | Journal article
DOI: 10.1093/nar/gkx1142
Contributors: Susanna Cogoi; Annalisa Ferino; Giulia Miglietta; Erik B Pedersen; Luigi E Xodo
Source: check_circle
Crossref

A photodynamic bifunctional conjugate for prostate cancer: an in vitro mechanistic study

Investigational New Drugs
2017 | Journal article
DOI: 10.1007/s10637-016-0396-x
EID:

2-s2.0-84990946728
Contributors: Rapozzi, V.; Varchi, G.; Della Pietra, E.; Ferroni, C.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

Nanocrystalline cellulose-fullerene: Novel conjugates

Carbohydrate Polymers
2017 | Journal article
DOI: 10.1016/j.carbpol.2017.01.068
EID:

2-s2.0-85011260313
Contributors: Herreros-López, A.; Carini, M.; Da Ros, T.; Carofiglio, T.; Marega, C.; La Parola, V.; Rapozzi, V.; Xodo, L.E.; Alshatwi, A.A.; Hadad, C. et al.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

RNA G-Quadruplexes in Kirsten Ras (KRAS) Oncogene as Targets for Small Molecules Inhibiting Translation

Journal of Medicinal Chemistry
2017-12-14 | Journal article
DOI: 10.1021/acs.jmedchem.7b00622
Contributors: Giulia Miglietta; Susanna Cogoi; Jessica Marinello; Giovanni Capranico; Alexander S. Tikhomirov; Andrey Shchekotikhin; Luigi E. Xodo
Source: check_circle
Crossref

Delayed cord clamping and cord gas analysis at birth.

Acta obstetricia et gynecologica Scandinavica
2017-09 | Journal article
DOI: 10.1111/aogs.13233
PMID: 28921502
Source: Self-asserted source
Luigi XODO via Europe PubMed Central
grade
Preferred source (of 2)‎

Critical role of hnRNP A1 in activating KRAS transcription in pancreatic cancer cells: A molecular mechanism involving G4 DNA

Biochimica et Biophysica Acta - General Subjects
2016 | Journal article
DOI: 10.1016/j.bbagen.2016.11.031
EID:

2-s2.0-85007417771
Contributors: Cogoi, S.; Rapozzi, V.; Cauci, S.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

G4 DNA in ras genes and its potential in cancer therapy

Biochimica et Biophysica Acta - Gene Regulatory Mechanisms
2016 | Journal article
DOI: 10.1016/j.bbagrm.2016.02.002
EID:

2-s2.0-84960361942
Contributors: Cogoi, S.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

Lipid-modified G4-decoy oligonucleotide anchored to nanoparticles: Delivery and bioactivity in pancreatic cancer cells

Scientific Reports
2016 | Journal article
DOI: 10.1038/srep38468
EID:

2-s2.0-85002924015
Contributors: Cogoi, S.; Jakobsen, U.; Pedersen, E.B.; Vogel, S.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

Photosensitizers binDing to nucleic acids as anticancer agents

Future Medicinal Chemistry
2016 | Journal article
DOI: 10.4155/fmc.15.180
EID:

2-s2.0-84958056600
Contributors: Xodo, L.E.; Cogoi, S.; Rapozzi, V.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

GC-elements controlling HRAS transcription form i-motif structures unfolded by heterogeneous ribonucleoprotein particle A1

Scientific Reports
2015 | Journal article
DOI: 10.1038/srep18097
EID:

2-s2.0-84950256344
Contributors: Miglietta, G.; Cogoi, S.; Pedersen, E.B.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

Nucleic Acid Targeted Therapy: G4 Oligonucleotides Downregulate HRAS in Bladder Cancer Cells through a Decoy Mechanism

ACS Medicinal Chemistry Letters
2015 | Journal article
DOI: 10.1021/acsmedchemlett.5b00315
EID:

2-s2.0-84949809222
Contributors: Miglietta, G.; Gouda, A.S.; Cogoi, S.; Pedersen, E.B.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

Potent Apoptotic Response Induced by Chloroacetamidine Anthrathiophenediones in Bladder Cancer Cells

Journal of Medicinal Chemistry
2015 | Journal article
DOI: 10.1021/acs.jmedchem.5b00409
EID:

2-s2.0-84937680751
Contributors: Cogoi, S.; Zorzet, S.; Shchekotikhin, A.E.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

Repeated sub-optimal photodynamic treatments with pheophorbide a induce an epithelial mesenchymal transition in prostate cancer cells via nitric oxide

Nitric Oxide - Biology and Chemistry
2015 | Journal article
DOI: 10.1016/j.niox.2015.02.005
EID:

2-s2.0-84923875765
Contributors: Della Pietra, E.; Simonella, F.; Bonavida, B.; Xodo, L.E.; Rapozzi, V.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

Anticancer activity of cationic porphyrins in melanoma tumour-bearing mice and mechanistic in vitro studies

Molecular Cancer
2014 | Journal article
DOI: 10.1186/1476-4598-13-75
EID:

2-s2.0-84897567871
Contributors: Rapozzi, V.; Zorzet, S.; Zacchigna, M.; Della Pietra, E.; Cogoi, S.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

Clicking porphyrins to magnetic nanoparticles for photodynamic therapy

ChemPlusChem
2014 | Journal article
DOI: 10.1002/cplu.201300276
EID:

2-s2.0-84893297618
Contributors: Thandu, M.; Rapozzi, V.; Xodo, L.; Albericio, F.; Comuzzi, C.; Cavalli, S.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

HRAS is silenced by two neighboring G-quadruplexes and activated by MAZ, a zinc-finger transcription factor with DNA unfolding property

Nucleic Acids Research
2014 | Journal article
DOI: 10.1093/nar/gku574
EID:

2-s2.0-84905565068
Contributors: Cogoi, S.; Shchekotikhin, A.E.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

Guanidino anthrathiophenediones as G-quadruplex binders: Uptake, intracellular localization, and anti-Harvey-ras gene activity in bladder cancer cells

Journal of Medicinal Chemistry
2013 | Journal article
DOI: 10.1021/jm3019063
EID:

2-s2.0-84876239403
Contributors: Cogoi, S.; Shchekotikhin, A.E.; Membrino, A.; Sinkevich, Y.B.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice

Nucleic Acids Research
2013 | Journal article
DOI: 10.1093/nar/gkt127
EID:

2-s2.0-84876246842
Contributors: Cogoi, S.; Zorzet, S.; Rapozzi, V.; Géci, I.; Pedersen, E.B.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

Nitric oxide-mediated activity in anti-cancer photodynamic therapy

Nitric Oxide - Biology and Chemistry
2013 | Journal article
DOI: 10.1016/j.niox.2013.01.002
EID:

2-s2.0-84873728416
Contributors: Rapozzi, V.; Della Pietra, E.; Zorzet, S.; Zacchigna, M.; Bonavida, B.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

The PDT activity of free and pegylated pheophorbide a against an amelanotic melanoma transplanted in C57/BL6 mice

Investigational New Drugs
2013 | Journal article
DOI: 10.1007/s10637-012-9844-4
EID:

2-s2.0-84873080333
Contributors: Rapozzi, V.; Zorzet, S.; Zacchigna, M.; Drioli, S.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

Editorial: Applications of the photodynamic therapy to cancer, water- and vector-borne diseases

Current Medicinal Chemistry
2012 | Journal article
DOI: 10.2174/092986712799034932
EID:

2-s2.0-84857540267
Contributors: Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

Photoactivated cationic alkyl-substituted porphyrin binding to g4-RNA in the 5′-UTR of KRAS oncogene represses translation

Chemical Communications
2012 | Journal article
DOI: 10.1039/c1cc15850c
EID:

2-s2.0-84055188686
Contributors: Faudale, M.; Cogoi, S.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

The chlorophyll catabolite pheophorbide a as a photosensitizer for the photodynamic therapy

Current Medicinal Chemistry
2012 | Journal article
DOI: 10.2174/092986712799034879
EID:

2-s2.0-84857620182
Contributors: Xodo, L.E.; Rapozzi, V.; Zacchigna, M.; Drioli, S.; Zorzet, S.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

G4-DNA formation in the HRAS promoter and rational design of decoy oligonucleotides for cancer therapy

PLoS ONE
2011 | Journal article
DOI: 10.1371/journal.pone.0024421
EID:

2-s2.0-80052532707
Contributors: Membrino, A.; Cogoi, S.; Pedersen, E.B.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

Metallation of pentaphyrin with Lu(III) dramatically increases reactive-oxygen species production and cell phototoxicity

European Journal of Medicinal Chemistry
2011 | Journal article
DOI: 10.1016/j.ejmech.2010.12.007
EID:

2-s2.0-79151485517
Contributors: Ballico, M.; Rapozzi, V.; Xodo, L.E.; Comuzzi, C.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

Pivotal role of nitric oxide (NO) induction by photodynamic therapy in tumor cells: Modification of the NF-κB/Snail/RKIP survival/anti-apoptotic loop

Forum on Immunopathological Diseases and Therapeutics
2011 | Journal article
DOI: 10.1615/ForumImmunDisTher.2011004418
EID:

2-s2.0-84857091126
Contributors: Rapozzi, V.; Bonavida, B.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

Primer extension reactions as a tool to uncover folding motifs within complex G-rich sequences: Analysis of the human KRAS NHE

Chemical Communications
2011 | Journal article
DOI: 10.1039/c1cc10269a
EID:

2-s2.0-79954427785
Contributors: Paramasivam, M.; Cogoi, S.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

Role of NF-κB/Snail/RKIP loop in the response of tumor cells to photodynamic therapy

Lasers in Surgery and Medicine
2011 | Journal article
DOI: 10.1002/lsm.21095
EID:

2-s2.0-80052066352
Contributors: Rapozzi, V.; Umezawa, K.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

Role of RKIP in sensitizing tumor cells to photodynamic therapy

Forum on Immunopathological Diseases and Therapeutics
2011 | Journal article
DOI: 10.1615/ForumImmunDisTher.v2.i2.50
EID:

2-s2.0-79958282644
Contributors: Rapozzi, V.; Umezawa, K.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

Cellular uptake and binding of guanidine-modified phthalocyanines to KRAS/HRAS G-quadruplexes

Chemical Communications
2010 | Journal article
DOI: 10.1039/b918964e
EID:

2-s2.0-75149116665
Contributors: Membrino, A.; Paramasivam, M.; Cogoi, S.; Alzeer, J.; Luedtke, N.W.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

Conjugated PDT drug: Photosensitizing activity and tissue distribution of PEGylated pheophorbide a

Cancer Biology and Therapy
2010 | Journal article
DOI: 10.4161/cbt.10.5.12536
EID:

2-s2.0-77957109697
Contributors: Rapozzi, V.; Zacchigna, M.; Biffi, S.; Garrovo, C.; Cateni, F.; Stebel, M.; Zorzet, S.; Bonora, G.M.; Drioli, S.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

Enhanced G4-DNA binding of 5,10,15,20 (N-propyl-4-pyridyl) porphyrin (TPrPyP4): A comparative study with TMPyP4

Chemical Communications
2010 | Journal article
DOI: 10.1039/c0cc01912g
EID:

2-s2.0-77957672862
Contributors: Cogoi, S.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

Photooxidation and phototoxicity of π-extended squaraines

Journal of Medicinal Chemistry
2010 | Journal article
DOI: 10.1021/jm901727j
EID:

2-s2.0-77949379072
Contributors: Rapozzi, V.; Beverina, L.; Salice, P.; Pagani, G.A.; Camerin, M.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

The KRAS promoter responds to Myc-associated zinc finger and poly(ADP-ribose) polymerase 1 proteins, which recognize a critical quadruplex-forming GA-element

Journal of Biological Chemistry
2010 | Journal article
DOI: 10.1074/jbc.M110.101923
EID:

2-s2.0-77954615589
Contributors: Cogoi, S.; Paramasivam, M.; Membrino, A.; Yokoyama, K.K.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier

Evidence that photoactivated pheophorbide a causes in human cancer cells a photodynamic effect involving lipid peroxidation

Cancer Biology and Therapy
2009 | Journal article
EID:

2-s2.0-68149149783
Contributors: Rapozzi, V.; Miculan, M.; Xodo, L.E.
Source: Self-asserted source
Luigi XODO via Scopus - Elsevier
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Peer review (46 reviews for 16 publications/grants)

Review activity for ACS applied materials & interfaces. (2)
Review activity for ACS medicinal chemistry letters. (1)
Review activity for ACS omega. (1)
Review activity for Advanced functional materials. (1)
Review activity for Advanced materials. (1)
Review activity for Biochemical and biophysical research communications. (2)
Review activity for Biochemical pharmacology. (2)
Review activity for Biochemistry. (2)
Review activity for Biochimica et biophysica acta. Molecular cell research (1)
Review activity for Biomedicine & pharmacotherapy. (4)
Review activity for Bioorganic chemistry. (1)
Review activity for Epigenomes. (1)
Review activity for International journal of molecular sciences. (1)
Review activity for iScience. (2)
Review activity for Journal of medicinal chemistry. (22)
Review activity for Journal of the American Chemical Society. (2)
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