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Japan

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Works (50 of 52)

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Page 1 of 2

Conditioned medium from stem cells derived from human exfoliated deciduous teeth ameliorates NASH via the Gut-Liver axis

Scientific reports
2021 | Journal article
Part of ISSN: 2045-2322
Source: Self-asserted source
Taichi Ohshiro

Monapinone Coupling Enzyme Produces Non-Natural Heterodimers

Catalysts
2021 | Journal article
Part of ISSN: 2073-4344
Source: Self-asserted source
Taichi Ohshiro

Inhibition of cholesteryl ester synthesis by polyacetylenes from Atractylodes rhizome

Bioorganic & medicinal chemistry letters
2020 | Journal article
Part of ISSN: 0960-894X
Source: Self-asserted source
Taichi Ohshiro

New Terpendole Congeners, Inhibitors of Sterol <i>O</i>-Acyltransferase, Produced by <i>Volutella citrinella</i> BF-0440

Molecules (Basel, Switzerland)
2020 | Journal article
Part of ISSN: 1420-3049
Source: Self-asserted source
Taichi Ohshiro

The Anti-atherogenic Activity of Beauveriolide Derivative BVD327, a Sterol O-Acyltransferase 2-Selective Inhibitor, in Apolipoprotein E Knockout Mice

Biological and pharmaceutical bulletin
2020 | Journal article
Part of ISSN: 0918-6158
Source: Self-asserted source
Taichi Ohshiro

Voluhemins, new inhibitors of sterol O-acyltransferase, produced by Volutella citrinella BF-0440

The Journal of antibiotics
2020 | Journal article
Part of ISSN: 0021-8820
Source: Self-asserted source
Taichi Ohshiro

Inhibition of neutral lipid synthesis by avarols from a marine sponge

Bioorganic & medicinal chemistry letters
2019 | Journal article
Part of ISSN: 0960-894X
Source: Self-asserted source
Taichi Ohshiro

A Mixture of Atropisomers Enhances Neutral Lipid Degradation in Mammalian Cells with Autophagy Induction

Scientific reports
2018 | Journal article
Part of ISSN: 2045-2322
Source: Self-asserted source
Taichi Ohshiro

Callyspongiamides A and B, sterol O-acyltransferase inhibitors, from the Indonesian marine sponge Callyspongia sp

Bioorganic & medicinal chemistry letters
2018 | Journal article
Part of ISSN: 0960-894X
Source: Self-asserted source
Taichi Ohshiro

Celludinones, new inhibitors of sterol O-acyltransferase, produced by Talaromyces cellulolyticus BF-0307

The Journal of antibiotics
2018 | Journal article
Part of ISSN: 0021-8820
Source: Self-asserted source
Taichi Ohshiro

Design and Synthesis of A-Ring Simplified Pyripyropene A Analogues as Potent and Selective Synthetic SOAT2 Inhibitors

ChemMedChem
2018 | Journal article
Part of ISSN: 1860-7179
Source: Self-asserted source
Taichi Ohshiro

Discovery of a Fungal Multicopper Oxidase That Catalyzes the Regioselective Coupling of a Tricyclic Naphthopyranone To Produce Atropisomers

Angewandte Chemie (International ed. in English)
2018 | Journal article
Part of ISSN: 1433-7851
Source: Self-asserted source
Taichi Ohshiro

Biseokeaniamides A, B, and C, Sterol O-Acyltransferase Inhibitors from an Okeania sp. Marine Cyanobacterium

Journal of natural products
2017 | Journal article
Part of ISSN: 0163-3864
Source: Self-asserted source
Taichi Ohshiro

Pseudopyronine B, an inhibitor of sterol O-acyltransferase, produced by Pseudomonas sp. BYK11209

The Journal of antibiotics
2017 | Journal article
Part of ISSN: 0021-8820
Source: Self-asserted source
Taichi Ohshiro

Selective inhibition of sterolO-acyltransferase 1 isozyme by beauveriolide III in intact cells

Scientific reports
2017 | Journal article
Part of ISSN: 2045-2322
Source: Self-asserted source
Taichi Ohshiro

7-Chlorofolipastatin, an inhibitor of sterol O-acyltransferase, produced by marine-derived Aspergillus ungui NKH-007

The Journal of antibiotics
2016 | Journal article
Part of ISSN: 0021-8820
Source: Self-asserted source
Taichi Ohshiro

Design, Synthesis, and Biological Evaluation of Beauveriolide Analogues Bearing Photoreactive Amino Acids

Bioorganic & medicinal chemistry letters
2016 | Journal article
Part of ISSN: 0009-2363
Source: Self-asserted source
Taichi Ohshiro

Discovery of SOAT2 inhibitors from synthetic small molecules

Bioorganic & medicinal chemistry letters
2016 | Journal article
Part of ISSN: 0960-894X
Source: Self-asserted source
Taichi Ohshiro

Acyltransferase inhibitors: a patent review (2010-present)

Expert opinion on therapeutic patents
2015 | Journal article
Part of ISSN: 1354-3776
Source: Self-asserted source
Taichi Ohshiro

In vitro metabolism of pyripyropene A and ACAT inhibitory activity of its metabolites

The Journal of antibiotics
2015 | Journal article
Part of ISSN: 0021-8820
Source: Self-asserted source
Taichi Ohshiro

New pyripyropene A derivatives, highly SOAT2-selective inhibitors, improve hypercholesterolemia and atherosclerosis in atherogenic mouse models

The Journal of pharmacology and experimental therapeutics
2015 | Journal article
Part of ISSN: 0022-3565
Source: Self-asserted source
Taichi Ohshiro

PRD125, a potent and selective inhibitor of sterol O-acyltransferase 2 markedly reduces hepatic cholesteryl ester accumulation and improves liver function in lysosomal acid lipase-deficient mice

The Journal of pharmacology and experimental therapeutics
2015 | Journal article
Part of ISSN: 0022-3565
Source: Self-asserted source
Taichi Ohshiro

Absence of Nceh1 augments 25-hydroxycholesterol-induced ER stress and apoptosis in macrophages

Journal of lipid research
2014 | Journal article
Part of ISSN: 0022-2275
Source: Self-asserted source
Taichi Ohshiro

Critical role of neutral cholesteryl ester hydrolase 1 in cholesteryl ester hydrolysis in murine macrophages

Journal of lipid research
2014 | Journal article
Part of ISSN: 0022-2275
Source: Self-asserted source
Taichi Ohshiro

Macrophage lipoprotein lipase modulates the development of atherosclerosis but not adiposity

Journal of lipid research
2013 | Journal article
Part of ISSN: 0022-2275
Source: Self-asserted source
Taichi Ohshiro

Synthesis and structure-activity relationship of pyripyropene A derivatives as potent and selective acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitors: part 1

Bioorganic & medicinal chemistry letters
2013 | Journal article
Part of ISSN: 0960-894X
Source: Self-asserted source
Taichi Ohshiro

Synthesis and structure-activity relationship of pyripyropene A derivatives as potent and selective acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitors: part 2

Bioorganic & medicinal chemistry letters
2013 | Journal article
Part of ISSN: 0960-894X
Source: Self-asserted source
Taichi Ohshiro

Synthesis and structure-activity relationship of pyripyropene A derivatives as potent and selective acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitors: part 3

Bioorganic & medicinal chemistry letters
2013 | Journal article
Part of ISSN: 0960-894X
Source: Self-asserted source
Taichi Ohshiro

The mechanism of action of bufalin in inhibition of lipid droplet accumulation in mouse macrophages

Biological and pharmaceutical bulletin
2013 | Journal article
Part of ISSN: 0918-6158
Source: Self-asserted source
Taichi Ohshiro

Conformationally restricted analog and biotin-labeled probe based on beauveriolide III

Bioorganic & medicinal chemistry letters
2012 | Journal article
Part of ISSN: 0960-894X
Source: Self-asserted source
Taichi Ohshiro

Interleukin-17 deficiency reduced vascular inflammation and development of atherosclerosis in Western diet-induced apoE-deficient mice

Biochemical and biophysical research communications
2012 | Journal article
Part of ISSN: 0006-291X
Source: Self-asserted source
Taichi Ohshiro

Liver-specific deletion of 3-hydroxy-3-methylglutaryl coenzyme A reductase causes hepatic steatosis and death

Arteriosclerosis, thrombosis, and vascular biology
2012 | Journal article
Part of ISSN: 1079-5642
Source: Self-asserted source
Taichi Ohshiro

New verticilides, inhibitors of acyl-CoA:cholesterol acyltransferase, produced by Verticillium sp. FKI-2679

The Journal of antibiotics
2012 | Journal article
Part of ISSN: 0021-8820
Source: Self-asserted source
Taichi Ohshiro

Isoform-specific inhibitors of ACATs: recent advances and promising developments

Future medicinal chemistry
2011 | Journal article
Part of ISSN: 1756-8919
Source: Self-asserted source
Taichi Ohshiro

Molecular analysis of a novel LCAT mutation (Gly179 → Arg) found in a patient with complete LCAT deficiency

Journal of atherosclerosis and thrombosis
2011 | Journal article
Part of ISSN: 1340-3478
Source: Self-asserted source
Taichi Ohshiro

Pyripyropene A, an acyl-coenzyme A:cholesterol acyltransferase 2-selective inhibitor, attenuates hypercholesterolemia and atherosclerosis in murine models of hyperlipidemia

Arteriosclerosis, thrombosis, and vascular biology
2011 | Journal article
Part of ISSN: 1079-5642
Source: Self-asserted source
Taichi Ohshiro

Ablation of neutral cholesterol ester hydrolase 1 accelerates atherosclerosis

Cell metabolism
2009 | Journal article
Part of ISSN: 1550-4131
Source: Self-asserted source
Taichi Ohshiro

The molecular target of rubimaillin in the inhibition of lipid droplet accumulation in macrophages

Biological and pharmaceutical bulletin
2009 | Journal article
Part of ISSN: 0918-6158
Source: Self-asserted source
Taichi Ohshiro

The selectivity of beauveriolide derivatives in inhibition toward the two isozymes of acyl-CoA: cholesterol acyltransferase

Chemical and pharmaceutical bulletin
2009 | Journal article
Part of ISSN: 0009-2363
Source: Self-asserted source
Taichi Ohshiro

Total synthesis of amidepsine B and revision of its absolute configuration

The Journal of antibiotics
2009 | Journal article
Part of ISSN: 0021-8820
Source: Self-asserted source
Taichi Ohshiro

Anti-atherosclerotic activity of triacsin C, an acyl-CoA synthetase inhibitor

The Journal of antibiotics
2008 | Journal article
Part of ISSN: 0021-8820
Source: Self-asserted source
Taichi Ohshiro

Molecular target of piperine in the inhibition of lipid droplet accumulation in macrophages

Biological and pharmaceutical bulletin
2008 | Journal article
Part of ISSN: 0918-6158
Source: Self-asserted source
Taichi Ohshiro

Selective inhibition of acyl-CoA:cholesterol acyltransferase 2 isozyme by flavasperone and sterigmatocystin from Aspergillus species

The Journal of antibiotics
2008 | Journal article
Part of ISSN: 0021-8820
Source: Self-asserted source
Taichi Ohshiro

Selectivity of pyripyropene derivatives in inhibition toward acyl-CoA:cholesterol acyltransferase 2 isozyme

The Journal of antibiotics
2008 | Journal article
Part of ISSN: 0021-8820
Source: Self-asserted source
Taichi Ohshiro

Synthesis and biological evaluation of a focused library of beauveriolides

Bioorganic medicinal chemistry letters
2008 | Journal article
Part of ISSN: 0960-894X
Source: Self-asserted source
Taichi Ohshiro

Fungal isobisvertinol, a new inhibitor of lipid droplet accumulation in mouse macrophages

Organic letters
2007 | Journal article
Part of ISSN: 1523-7060
Source: Self-asserted source
Taichi Ohshiro

Selectivity of microbial acyl-CoA: cholesterol acyltransferase inhibitors toward isozymes

The Journal of antibiotics
2007 | Journal article
Part of ISSN: 0021-8820
Source: Self-asserted source
Taichi Ohshiro

Absolute stereochemistry of fungal beauveriolide III and ACAT inhibitory activity of four stereoisomers

The Journal of organic chemistry
2006 | Journal article
Part of ISSN: 0022-3263
Source: Self-asserted source
Taichi Ohshiro

Molecular target of decursins in the inhibition of lipid droplet accumulation in macrophages

Biological and pharmaceutical bulletin
2006 | Journal article
Part of ISSN: 0918-6158
Source: Self-asserted source
Taichi Ohshiro

Discovery of halogenated eurypamide B analogues as inhibitors of lipid droplet accumulation in macrophages

Bioorganic & medicinal chemistry letters
2005 | Journal article
Part of ISSN: 0960-894X
Source: Self-asserted source
Taichi Ohshiro
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