Personal information

Lipids, Cardiovascular diseases, NAFLD, liver diseases, metabolism, endothelium
United Kingdom

Activities

Employment (4)

University of Leeds: Leeds, GB

2024-04-01 to present | Lecturer of Nutrient and Metabolism (Faculty of Environment, School of Food Science and Nutrition)
Employment
Source: Self-asserted source
Laeticia Lichtenstein

University of Leeds: Leeds, West Yorkshire, GB

2017-12-01 to 2024-03-31 | Post Doctoral Research Assistant (School of Medicine, LICAMM)
Employment
Source: Self-asserted source
Laeticia Lichtenstein

University of Leeds: Leeds, West Yorkshire, GB

2017-05-01 to 2017-11-30 | Visiting scientist (School of Medicine, LICAMM)
Employment
Source: Self-asserted source
Laeticia Lichtenstein

INSERM Délégation régionale Midi-Pyrenees Limousin: Toulouse, Midi-Pyrénées, FR

2010-01-01 to 2016-11-30 | Post Doctorant (I2MC)
Employment
Source: Self-asserted source
Laeticia Lichtenstein

Education and qualifications (1)

Wageningen University & Research: Wageningen, NL

2005-11-01 to 2009-10-31 | Post graduates studying for PhD (Nutrition , Metabolism and Genomics)
Qualification
Source: Self-asserted source
Laeticia Lichtenstein

Professional activities (1)

European Association for the Study of the Liver: Geneve, GE, CH

2018-01-01 to present
Membership
Source: Self-asserted source
Laeticia Lichtenstein

Works (33)

Endothelial force sensing signals to parenchymal cells to regulate bile and plasma lipids

Science Advances
2024-09-27 | Journal article
Contributors: Laeticia Lichtenstein; Chew W. Cheng; Muath Bajarwan; Elizabeth L. Evans; Hannah J. Gaunt; Fiona Bartoli; Eulashini Chuntharpursat-Bon; Shaili Patel; Charalampos Konstantinou; T. Simon Futers et al.
Source: check_circle
Crossref

Lipid regulatory effects of endothelial force sensing

EAS 2024
2024-08 | Conference abstract | Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Visualization, Writing - original draft, Writing - review & editing, Validation
Contributors: Laeticia Lichtenstein; Chew W Cheng; Elizabeth L Evans; Hannah J Gaunt; Fiona Bartoli; Eulashini Chuntharpursat-Bon; Shaili Patel; Charalampos Konstantinou; T. Simon Futers; Melanie Reay et al.
Source: Self-asserted source
Laeticia Lichtenstein

PIEZO1 force sensing controls global lipid homeostasis

2023-07-25 | Preprint
Contributors: Laeticia Lichtenstein; Chew W Cheng; Elizabeth L Evans; Hannah J Gaunt; Fiona Bartoli; Eulashini Chuntharpursat-Bon; Shaili Patel; Charalampos Konstantinou; T Simon Futers; Melanie Reay et al.
Source: check_circle
Crossref

Independent endothelial functions of PIEZO1 and TRPV4 in hepatic portal vein and predominance of PIEZO1 in mechanical and osmotic stress.

Liver international : official journal of the International Association for the Study of the Liver
2023-06 | Journal article
Contributors: Endesh N; Chuntharpursat-Bon E; Revill C; Yuldasheva NY; Futers TS; Parsonage G; Humphreys N; Adamson A; Morley LC; Cubbon RM et al.
Source: Self-asserted source
Laeticia Lichtenstein via Europe PubMed Central

PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing.

Communications biology
2023-04 | Journal article
Contributors: Chuntharpursat-Bon E; Povstyan OV; Ludlow MJ; Carrier DJ; Debant M; Shi J; Gaunt HJ; Bauer CC; Curd A; Simon Futers T et al.
Source: Self-asserted source
Laeticia Lichtenstein via Europe PubMed Central

Improved PIEZO1 agonism through 4-benzoic acid modification of Yoda1.

British journal of pharmacology
2023-01 | Journal article
Contributors: Parsonage G; Cuthbertson K; Endesh N; Murciano N; Hyman AJ; Revill CH; Povstyan OV; Chuntharpursat-Bon E; Debant M; Ludlow MJ et al.
Source: Self-asserted source
Laeticia Lichtenstein via Europe PubMed Central

Cixutumumab reveals a critical role for IGF-1 in adipose and hepatic tissue remodelling during the development of diet-induced obesity.

Adipocyte
2022-12 | Journal article
Contributors: Imrie H; Viswambharan H; Haywood NJ; Bridge KI; Yuldasheva NY; Galloway S; Simmons KJ; Cubbon RM; Sukumar P; Watt NT et al.
Source: Self-asserted source
Laeticia Lichtenstein via Europe PubMed Central

Global PIEZO1 Gain-of-Function Mutation Causes Cardiac Hypertrophy and Fibrosis in Mice

Cells
2022-04 | Journal article | Author
Contributors: Fiona Bartoli; Elizabeth L. Evans; Nicola M. Blythe; Leander Stewart; Eulashini Chuntharpursat-Bon; Marjolaine Debant; Katie E. Musialowski; Laeticia Lichtenstein; Gregory Parsonage; T. Simon Futers et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Endothelial Piezo1 sustains muscle capillary density and contributes to physical activity.

The Journal of clinical investigation
2022-03 | Journal article
Contributors: Bartoli F; Debant M; Chuntharpursat-Bon E; Evans EL; Musialowski KE; Parsonage G; Morley LC; Futers TS; Sukumar P; Bowen TS et al.
Source: Self-asserted source
Laeticia Lichtenstein via Europe PubMed Central

Sphingomyelinase Disables Inactivation in Endogenous PIEZO1 Channels.

Cell reports
2020-10 | Journal article
Contributors: Shi J; Hyman AJ; De Vecchis D; Chong J; Lichtenstein L; Futers TS; Rouahi M; Salvayre AN; Auge N; Kalli AC et al.
Source: Self-asserted source
Laeticia Lichtenstein via Europe PubMed Central

RNA and the PIEZO force sensor

Cell Research
2020-10-03 | Journal article
Contributors: David J. Beech; Laeticia Lichtenstein
Source: check_circle
Crossref

RBCs prevent rapid PIEZO1 inactivation and expose slow deactivation as a mechanism of dehydrated hereditary stomatocytosis

Blood
2020-07-02 | Journal article
Contributors: Elizabeth L. Evans; Oleksandr V. Povstyan; Dario De Vecchis; Fraser Macrae; Laeticia Lichtenstein; T. Simon Futers; Gregory Parsonage; Neil E. Humphreys; Antony Adamson; Antreas C. Kalli et al.
Source: check_circle
Crossref

Shear stress activates ADAM10 sheddase to regulate Notch1 via the Piezo1 force sensor in endothelial cells

eLife
2020-06-02 | Journal article
Contributors: Vincenza Caolo; Marjolaine Debant; Naima Endesh; T Simon Futers; Laeticia Lichtenstein; Fiona Bartoli; Gregory Parsonage; Elizabeth AV Jones; David J Beech
Source: check_circle
Crossref

Sphingomyelinase disables Piezo1 channel inactivation to enable sustained response to mechanical force

2019-10-04 | Other
Contributors: Jian Shi; Adam J Hyman; Dario De Vecchis; Jiehan Chong; Laeticia Lichtenstein; T. Simon Futers; Myriam Rouahi; Anne Negre Salvayre; Nathalie Auge; Antreas C Kalli et al.
Source: check_circle
Crossref

Piezo1 channel activates ADAM10 sheddase to regulate Notch1 and gene expression

2019-08-12 | Other
Contributors: Vincenza Caolo; Marjolaine Debant; Naima Endesh; T Simon Futers; Laeticia Lichtenstein; Gregory Parsonage; Elizabeth AV Jones; David J Beech
Source: check_circle
Crossref

Short-term cooling increases serum triglycerides and small high-density lipoprotein levels in humans

Journal of Clinical Lipidology
2017-07 | Journal article
Part of ISSN: 1933-2874
Source: Self-asserted source
Laeticia Lichtenstein

A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice

Nature Medicine
2017-01 | Journal article
Part of ISSN: 1078-8956
Part of ISSN: 1546-170X
Source: Self-asserted source
Laeticia Lichtenstein

Serum levels of mitochondrial inhibitory factor 1 are independently associated with long-term prognosis in coronary artery disease: the GENES Study

BMC Medicine
2016-12 | Journal article
Part of ISSN: 1741-7015
Source: Self-asserted source
Laeticia Lichtenstein

RNY-derived small RNAs as a signature of coronary artery disease

BMC Medicine
2015-12 | Journal article
Part of ISSN: 1741-7015
Source: Self-asserted source
Laeticia Lichtenstein

Increased atherosclerosis in P2Y13/apolipoprotein E double-knockout mice: contribution of P2Y13 to reverse cholesterol transport

Cardiovascular Research
2015-05-01 | Journal article
Part of ISSN: 1755-3245
Part of ISSN: 0008-6363
Source: Self-asserted source
Laeticia Lichtenstein

Ecto-F1-ATPase/P2Y pathways in metabolic and vascular functions of high density lipoproteins

Atherosclerosis
2015-01 | Journal article
Part of ISSN: 0021-9150
Source: Self-asserted source
Laeticia Lichtenstein

ANGPTL4 is produced by entero-endocrine cells in the human intestinal tract

Histochemistry and Cell Biology
2014-04 | Journal article
Part of ISSN: 0948-6143
Part of ISSN: 1432-119X
Source: Self-asserted source
Laeticia Lichtenstein

Lack of P2Y13 in mice fed a high cholesterol diet results in decreased hepatic cholesterol content, biliary lipid secretion and reverse cholesterol transport

Nutrition & Metabolism
2013 | Journal article
Part of ISSN: 1743-7075
Source: Self-asserted source
Laeticia Lichtenstein

Serum IF1 concentration is independently associated to HDL levels and to coronary heart disease: the GENES study

Journal of Lipid Research
2013-09 | Journal article
Part of ISSN: 0022-2275
Part of ISSN: 1539-7262
Source: Self-asserted source
Laeticia Lichtenstein

Chronic pharmacological activation of P2Y13 receptor in mice decreases HDL-cholesterol level by increasing hepatic HDL uptake and bile acid secretion

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
2013-04 | Journal article
Part of ISSN: 1388-1981
Source: Self-asserted source
Laeticia Lichtenstein

Angptl4 Protects against Severe Proinflammatory Effects of Saturated Fat by Inhibiting Fatty Acid Uptake into Mesenteric Lymph Node Macrophages

Cell Metabolism
2010-12 | Journal article
Part of ISSN: 1550-4131
Source: Self-asserted source
Laeticia Lichtenstein

Ecto-F₁-ATPase: a moonlighting protein complex and an unexpected apoA-I receptor.

World journal of gastroenterology
2010-12-01 | Journal article
Source: Self-asserted source
Laeticia Lichtenstein

P2Y13 receptor is critical for reverse cholesterol transport

Hepatology
2010-09-09 | Journal article
Part of ISSN: 0270-9139
Source: Self-asserted source
Laeticia Lichtenstein

Induction of Cardiac Angptl4 by Dietary Fatty Acids Is Mediated by Peroxisome Proliferator-Activated Receptor β/δ and Protects Against Fatty Acid–Induced Oxidative Stress

Circulation Research
2010-06-11 | Journal article
Part of ISSN: 0009-7330
Part of ISSN: 1524-4571
Source: Self-asserted source
Laeticia Lichtenstein

Modulation of plasma TG lipolysis by Angiopoietin-like proteins and GPIHBP1

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
2010-04 | Journal article
Part of ISSN: 1388-1981
Source: Self-asserted source
Laeticia Lichtenstein

Transcription of the human uncoupling protein 3 gene is governed by a complex interplay between the promoter and intronic sequences

Diabetologia
2009-08 | Journal article
Part of ISSN: 0012-186X
Part of ISSN: 1432-0428
Source: Self-asserted source
Laeticia Lichtenstein

Caloric Restriction and Exercise Increase Plasma ANGPTL4 Levels in Humans via Elevated Free Fatty Acids

Arteriosclerosis, Thrombosis, and Vascular Biology
2009-06 | Journal article
Part of ISSN: 1079-5642
Part of ISSN: 1524-4636
Source: Self-asserted source
Laeticia Lichtenstein

Angptl4 upregulates cholesterol synthesis in liver via inhibition of LPL- and HL-dependent hepatic cholesterol uptake.

Arteriosclerosis, thrombosis, and vascular biology
2007-08-30 | Journal article
Source: Self-asserted source
Laeticia Lichtenstein

Peer review (1 review for 1 publication/grant)

Review activity for European journal of nutrition. (1)