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Works (6)

Optimization of base editors for the functional correction of SMN2 as a treatment for spinal muscular atrophy

Nature Biomedical Engineering
2023-12-06 | Journal article
DOI: 10.1038/s41551-023-01132-z
Contributors: Christiano R. R. Alves; Leillani L. Ha; Rebecca Yaworski; Emma R. Sutton; Cicera R. Lazzarotto; Kathleen A. Christie; Aoife Reilly; Ariane Beauvais; Roman M. Doll; Demitri de la Cruz et al.
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A temperature-tolerant CRISPR base editor mediates highly efficient and precise gene editing in Drosophila

Science Advances
2023-09 | Journal article
DOI: 10.1126/sciadv.adj1568
Contributors: Roman M. Doll; Michael Boutros; Fillip Port
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Precise DNA cleavage using CRISPR-SpRYgests

Nature Biotechnology
2023-03 | Journal article
DOI: 10.1038/s41587-022-01492-y
Contributors: Kathleen A. Christie; Jimmy A. Guo; Rachel A. Silverstein; Roman M. Doll; Megumu Mabuchi; Hannah E. Stutzman; Jiecong Lin; Linyuan Ma; Russell T. Walton; Luca Pinello et al.
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Base editing as a genetic treatment for spinal muscular atrophy

2023-01-21 | Preprint
DOI: 10.1101/2023.01.20.524978
Contributors: Christiano R. R. Alves; Leillani L. Ha; Rebecca Yaworski; Cicera R. Lazzarotto; Kathleen A. Christie; Aoife Reilly; Ariane Beauvais; Roman M. Doll; Demitri de la Cruz; Casey A. Maguire et al.
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A temperature-tolerant CRISPR base editor mediates highly efficient and precise gene inactivationin vivo

2022-12-13 | Preprint
DOI: 10.1101/2022.12.13.520203
Contributors: Roman M. Doll; Michael Boutros; Fillip Port
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Precise DNA Cloning via PAMless CRISPR-SpRYgests

2022-01-12 | Preprint
DOI: 10.1101/2022.01.11.474553
Contributors: Kathleen A. Christie; Jimmy A. Guo; Rachel A. Silverstein; Roman M. Doll; Megumu Mabuchi; Hannah E. Stutzman; Linyuan Ma; G. Brett Robb; Benjamin P. Kleinstiver
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