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Cellular Immunity Garvan - J. Sprent

Keywords

Transplantation tolerance, Tregs, Mixed chimerism

Countries

Austria

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Employment (2)

Medical University of Vienna: Vienna, AT

2022-08-01 to present | Associate Professor (Department of Cardiac Surgery)
Employment
Source: Self-asserted source
Nina Pilat

Garvan Institute of Medical Research: Darlinghurst, NSW, AU

2015-06-15 to 2016-08-31 | Visiting Scientist/Postdoc (Immunology)
Employment
Source: Self-asserted source
Nina Pilat

Works (50 of 54)

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The potential for Treg-enhancing therapies in transplantation

Clinical and Experimental Immunology
2023-03-16 | Journal article
DOI: 10.1093/cei/uxac118
Contributors: Romy Steiner; Nina Pilat
Source: check_circle
Crossref

Inadvertent stem cell transfer demonstrating a way for tolerance induction

Kidney International
2023-01 | Journal article
DOI: 10.1016/j.kint.2022.11.007
Part of ISSN: 0085-2538
Contributors: Nina Pilat
Source: Self-asserted source
Nina Pilat

Treg Therapy for the Induction of Immune Tolerance in Transplantation—Not Lost in Translation?

International Journal of Molecular Sciences
2023-01-16 | Journal article
DOI: 10.3390/ijms24021752
Contributors: Nina Pilat; Romy Steiner; Jonathan Sprent
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Joining Forces in Basic Science: ITS Meeting 2.0

Transplant International
2022-09-26 | Journal article
DOI: 10.3389/ti.2022.10843
Part of ISSN: 1432-2277
Contributors: Nina Pilat; Fadi Issa; Xunrong Luo; Anita Chong; Jonathan Bromberg; Katja Kotsch
Source: Self-asserted source
Nina Pilat

Treg Therapies Revisited: Tolerance Beyond Deletion

Frontiers in Immunology
2021 | Journal article
DOI: 10.3389/fimmu.2020.622810
EID:

2-s2.0-85101040376

Part of ISSN: 16643224
Contributors: Pilat, N.; Sprent, J.
Source: Self-asserted source
Nina Pilat via Scopus - Elsevier

Impact of Graft-Resident Leucocytes on Treg Mediated Skin Graft Survival

Frontiers in Immunology
2021-11-29 | Journal article
DOI: 10.3389/fimmu.2021.801595
Part of ISSN: 1664-3224
Contributors: Romy Steiner; Anna M. Weijler; Thomas Wekerle; Jonathan Sprent; Nina Pilat
Source: Self-asserted source
Nina Pilat

T‐ and B‐cell therapy in solid organ transplantation: current evidence and future expectations

Transplant International
2021-09 | Journal article
DOI: 10.1111/tri.13972
Contributors: Nina Pilat; Katia Lefsihane; Sophie Brouard; Katja Kotsch; Christine Falk; Romy Steiner; Olivier Thaunat; Floriane Fusil; Nuria Montserrat; Cristiano Amarelli et al.
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In vivo Treg expansion under costimulation blockade targets early rejection and improves long-term outcome.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
2021-06 | Journal article
DOI: 10.1111/ajt.16724
PMID: 34152692
Contributors: Schwarz C; Mahr B; Muckenhuber M; Marianne Weijler A; Unger LW; Pilat N; Latus M; Regele H; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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Distinct roles for major and minor antigen barriers in chimerism-based tolerance under irradiation-free conditions

American Journal of Transplantation
2021-03 | Journal article
DOI: 10.1111/ajt.16177
Contributors: Benedikt Mahr; Nina Pilat; Nicolas Granofszky; Moritz Muckenhuber; Lukas W. Unger; Anna M. Weijler; Mario Wiletel; Romy Steiner; Lisa Dorner; Heinz Regele et al.
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Methods to Detect MHC-Specific IgE in Mice and Men

Frontiers in Immunology
2020 | Journal article
DOI: 10.3389/fimmu.2020.586856
EID:

2-s2.0-85098077625

Part of ISSN: 16643224
Contributors: Weijler, A.M.; Mucha, J.; Farkas, A.M.; Baranyi, U.; Pilat, N.; Cho, A.; Muckenhuber, M.; Hopf, S.; Wahrmann, M.; Linhart, B. et al.
Source: Self-asserted source
Nina Pilat via Scopus - Elsevier

Allograft rejection is associated with development of functional IgE specific for donor MHC antigens

Journal of Allergy and Clinical Immunology
2019 | Journal article
DOI: 10.1016/j.jaci.2018.06.034
EID:

2-s2.0-85051067243

Part of ISSN: 10976825 00916749
Contributors: Farkas, A.M.; Baranyi, U.; Böhmig, G.A.; Unger, L.; Hopf, S.; Wahrmann, M.; Regele, H.; Mahr, B.; Schwarz, C.; Hock, K. et al.
Source: Self-asserted source
Nina Pilat via Scopus - Elsevier

Treg-mediated prolonged survival of skin allografts without immunosuppression

Proceedings of the National Academy of Sciences
2019-07-02 | Journal article
DOI: 10.1073/pnas.1903165116
Contributors: Nina Pilat; Mario Wiletel; Anna M. Weijler; Romy Steiner; Benedikt Mahr; Joanna Warren; Theresa M. Corpuz; Thomas Wekerle; Kylie E. Webster; Jonathan Sprent
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Hybrid resistance to parental bone marrow grafts in nonlethally irradiated mice

American Journal of Transplantation
2019-02 | Journal article
DOI: 10.1111/ajt.15146
Contributors: Benedikt Mahr; Nina Pilat; Nicolas Granofszky; Mario Wiletel; Moritz Muckenhuber; Svenja Maschke; Karin Hock; Thomas Wekerle
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Blockade of adhesion molecule lymphocyte function–associated antigen-1 improves long-term heart allograft survival in mixed chimeras

The Journal of Heart and Lung Transplantation
2018-09 | Journal article
DOI: 10.1016/j.healun.2018.03.016
Contributors: Nina Pilat; Philipp Sabler; Christoph Klaus; Benedikt Mahr; Lukas Unger; Karin Hock; Mario Wiletel; Christoph Schwarz; Ivan Kristo; Heinz Regele et al.
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CTLA4Ig Improves Murine iTreg Induction via TGFβ and Suppressor Function In Vitro

Journal of Immunology Research
2018-07-02 | Journal article
DOI: 10.1155/2018/2484825
Contributors: Nina Pilat; Benedikt Mahr; Martina Gattringer; Ulrike Baranyi; Thomas Wekerle
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Anti-Interleukin-6 Promotes Allogeneic Bone Marrow Engraftment and Prolonged Graft Survival in an Irradiation-Free Murine Transplant Model.

Frontiers in immunology
2017 | Journal article
DOI: 10.3389/fimmu.2017.00821
PMID: 28769930
PMC: PMC5515831
Contributors: Granofszky N; Farkas AM; Muckenhuber M; Mahr B; Unger L; Maschke S; Pilat N; Holly R; Wiletel M; Regele H et al.
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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Combining Adoptive Treg Transfer with Bone Marrow Transplantation for Transplantation Tolerance.

Current transplantation reports
2017 | Journal article
DOI: 10.1007/s40472-017-0164-7
PMID: 29201599
PMC: PMC5691126
Contributors: Pilat N; Granofszky N; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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Regulatory T Cells Promote Natural Killer Cell Education in Mixed Chimeras

American Journal of Transplantation
2017-12 | Journal article
DOI: 10.1111/ajt.14342
Contributors: B. Mahr; N. Pilat; S. Maschke; N. Granofszky; C. Schwarz; L. Unger; K. Hock; A.M. Farkas; C. Klaus; H. Regele et al.
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IL-2 / α-IL-2 Complex Treatment Cannot Be Substituted for the Adoptive Transfer of Regulatory T cells to Promote Bone Marrow Engraftment.

2016 | Journal article
DOI: 10.1371/journal.pone.0146245
PMID: 26731275
PMC: PMC4701413
Contributors: Mahr B; Unger L; Hock K; Pilat N; Baranyi U; Schwarz C; Maschke S; Farkas AM; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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Minor Antigen Disparities Impede Induction of Long Lasting Chimerism and Tolerance through Bone Marrow Transplantation with Costimulation Blockade

Journal of Immunology Research
2016 | Journal article
DOI: 10.1155/2016/8635721
Contributors: Sinda Bigenzahn; Ines Pree; Christoph Klaus; Nina Pilat; Benedikt Mahr; Elisabeth Schwaiger; Patrick Nierlich; Friedrich Wrba; Thomas Wekerle
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Minor Antigen Disparities Impede Induction of Long Lasting Chimerism and Tolerance through Bone Marrow Transplantation with Costimulation Blockade.

2016 | Journal article
PMID: 27872868
Contributors: Bigenzahn S; Pree I; Klaus C; Pilat N; Mahr B; Schwaiger E; Nierlich P; Wrba F; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central

The Immunosuppressive Effect of CTLA4 Immunoglobulin Is Dependent on Regulatory T Cells at Low But Not High Doses

American Journal of Transplantation
2016-12 | Journal article
DOI: 10.1111/ajt.13872
Contributors: C. Schwarz; L. Unger; B. Mahr; K. Aumayr; H. Regele; A. M. Farkas; K. Hock; N. Pilat; T. Wekerle
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Incomplete clonal deletion as prerequisite for tissue-specific minor antigen tolerization.

2016-05 | Journal article
PMID: 27699263
PMC: PMC5033814
Contributors: Pilat N; Mahr B; Unger L; Hock K; Schwarz C; Farkas AM; Baranyi U; Wrba F; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central

Anti-OX40L alone or in combination with anti-CD40L and CTLA4Ig does not inhibit the humoral and cellular response to a major grass pollen allergen.

2016-02 | Journal article
DOI: 10.1111/cea.12661
PMID: 26464312
Contributors: Gattringer M; Baranyi U; Pilat N; Hock K; Klaus C; Ramsey HE; Wrba F; Valenta R; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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Polyclonal Recipient nTregs Are Superior to Donor or Third-Party Tregs in the Induction of Transplantation Tolerance.

2015 | Journal article
DOI: 10.1155/2015/562935
PMID: 26273682
PMC: PMC4530277
Contributors: Pilat N; Klaus C; Hock K; Baranyi U; Unger L; Mahr B; Farkas AM; Wrba F; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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Rapamycin and CTLA4Ig synergize to induce stable mixed chimerism without the need for CD40 blockade.

2015-06 | Journal article
DOI: 10.1111/ajt.13154
PMID: 25783859
Contributors: Pilat N; Klaus C; Schwarz C; Hock K; Oberhuber R; Schwaiger E; Gattringer M; Ramsey H; Baranyi U; Zelger B et al.
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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Assessing the TP53 marker type in patients treated with or without neoadjuvant chemotherapy for resectable colorectal liver metastases: a p53 Research Group study.

2015-05 | Journal article
DOI: 10.1016/j.ejso.2015.02.003
PMID: 25773284
Contributors: Pilat N; Grünberger T; Längle F; Mittlböck M; Perisanidis B; Kappel S; Wolf B; Starlinger P; Kührer I; Mühlbacher F et al.
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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Donor CD4 T cells trigger costimulation blockade-resistant donor bone marrow rejection through bystander activation requiring IL-6.

2014-09 | Journal article
DOI: 10.1111/ajt.12823
PMID: 25100658
Contributors: Hock K; Pilat N; Baranyi U; Mahr B; Gattringer M; Klaus C; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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T-regulatory cell treatment prevents chronic rejection of heart allografts in a murine mixed chimerism model.

2014-04 | Journal article
DOI: 10.1016/j.healun.2013.11.004
PMID: 24468120
PMC: PMC3991417
Contributors: Pilat N; Farkas AM; Mahr B; Schwarz C; Unger L; Hock K; Oberhuber R; Aumayr K; Wrba F; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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Implication for bone marrow derived stem cells in hepatocyte regeneration after orthotopic liver transplantation.

2013 | Journal article
DOI: 10.1155/2013/310612
PMID: 24109514
PMC: PMC3784276
Contributors: Pilat N; Unger L; Berlakovich GA
Source: Self-asserted source
Nina Pilat via Europe PubMed Central

Engraftment of retrovirally transduced Bet v 1-GFP expressing bone marrow cells leads to allergen-specific tolerance.

2013-09 | Journal article
DOI: 10.1016/j.imbio.2013.03.007
PMID: 23623394
Contributors: Gattringer M; Baranyi U; Pilat N; Hock K; Klaus C; Buchberger E; Ramsey H; Iacomini J; Valenta R; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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The site of allergen expression in hematopoietic cells determines the degree and quality of tolerance induced through molecular chimerism.

2013-09 | Journal article
DOI: 10.1002/eji.201243277
PMID: 23765421
PMC: PMC3816328
Contributors: Baranyi U; Gattringer M; Farkas AM; Hock K; Pilat N; Iacomini J; Valenta R; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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CTLA4-Ig immunosuppressive activity at the level of dendritic cell/T cell crosstalk.

2013-03 | Journal article
DOI: 10.1016/j.intimp.2013.02.007
PMID: 23434857
PMC: PMC3629566
Contributors: Mayer E; Hölzl M; Ahmadi S; Dillinger B; Pilat N; Fuchs D; Wekerle T; Heitger A
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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Anti-LFA-1 or rapamycin overcome costimulation blockade-resistant rejection in sensitized bone marrow recipients.

2013-02 | Journal article
DOI: 10.1111/tri.12021
PMID: 23240587
Contributors: Ramsey H; Pilat N; Hock K; Klaus C; Unger L; Schwarz C; Baranyi U; Gattringer M; Schwaiger E; Wrba F et al.
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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No evidence for recipient-derived hepatocytes in serial biopsies of sex-mismatched liver transplants.

2012-11 | Journal article
DOI: 10.1097/TP.0b013e318269e68d
PMID: 23034562
Contributors: Pilat N; Schoppmann S; Stift J; Mazal P; Wekerle T; Berlakovich GA
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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Modulating T-cell costimulation as new immunosuppressive concept in organ transplantation.

2012-08 | Journal article
DOI: 10.1097/MOT.0b013e328355fc94
PMID: 22790071
Contributors: Pilat N; Schwarz C; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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Persistent molecular microchimerism induces long-term tolerance towards a clinically relevant respiratory allergen.

2012-08 | Journal article
DOI: 10.1111/j.1365-2222.2012.04049.x
PMID: 22805476
PMC: PMC3586683
Contributors: Baranyi U; Pilat N; Gattringer M; Linhart B; Klaus C; Schwaiger E; Iacomini J; Valenta R; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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Belatacept and Tregs: friends or foes?

2012-04 | Journal article
DOI: 10.2217/imt.12.13
PMID: 22512625
Contributors: Pilat N; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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Dipeptidyl peptidase IV (DPPIV/CD26) inhibition does not improve engraftment of unfractionated syngeneic or allogeneic bone marrow after nonmyeloablative conditioning.

2012-02 | Journal article
DOI: 10.1016/j.exphem.2011.10.010
PMID: 22085453
PMC: PMC3265670
Contributors: Schwaiger E; Klaus C; Matheeussen V; Baranyi U; Pilat N; Ramsey H; Korom S; De Meester I; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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Mixed chimerism through donor bone marrow transplantation: a tolerogenic cell therapy for application in organ transplantation.

2012-02 | Journal article
DOI: 10.1097/MOT.0b013e32834ee68b
PMID: 22186093
Contributors: Pilat N; Hock K; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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IDO and regulatory T cell support are critical for cytotoxic T lymphocyte-associated Ag-4 Ig-mediated long-term solid organ allograft survival.

2012-01 | Journal article
DOI: 10.4049/jimmunol.1002777
PMID: 22131334
PMC: PMC3249458
Contributors: Sucher R; Fischler K; Oberhuber R; Kronberger I; Margreiter C; Ollinger R; Schneeberger S; Fuchs D; Werner ER; Watschinger K et al.
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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Costimulatory pathways in transplantation.

2011-08 | Journal article
DOI: 10.1016/j.smim.2011.04.002
PMID: 21616680
PMC: PMC3203219
Contributors: Pilat N; Sayegh MH; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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Therapeutic efficacy of polyclonal tregs does not require rapamycin in a low-dose irradiation bone marrow transplantation model.

2011-08 | Journal article
DOI: 10.1097/TP.0b013e3182241133
PMID: 21697774
Contributors: Pilat N; Klaus C; Gattringer M; Jaeckel E; Wrba F; Golshayan D; Baranyi U; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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Mechanistic and therapeutic role of regulatory T cells in tolerance through mixed chimerism.

2010-12 | Journal article
DOI: 10.1097/MOT.0b013e3283401755
PMID: 20881493
Contributors: Pilat N; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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The role of natural killer T cells in costimulation blockade-based mixed chimerism.

2010-11 | Journal article
DOI: 10.1111/j.1432-2277.2010.01120.x
PMID: 20536788
PMC: PMC2992941
Contributors: Nierlich PN; Klaus C; Bigenzahn S; Pilat N; Koporc Z; Pree I; Baranyi U; Taniguchi M; Muehlbacher F; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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Transplantation tolerance through mixed chimerism.

2010-10 | Journal article
DOI: 10.1038/nrneph.2010.110
PMID: 20808286
Contributors: Pilat N; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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Combining Treg therapy with mixed chimerism: Getting the best of both worlds.

2010-07 | Journal article
DOI: 10.4161/chim.1.1.12964
PMID: 21327149
PMC: PMC3035111
Contributors: Pilat N; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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Treg-therapy allows mixed chimerism and transplantation tolerance without cytoreductive conditioning.

2010-04 | Journal article
DOI: 10.1111/j.1600-6143.2010.03018.x
PMID: 20148810
PMC: PMC2856406
Contributors: Pilat N; Baranyi U; Klaus C; Jaeckel E; Mpofu N; Wrba F; Golshayan D; Muehlbacher F; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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A chimerism-based approach to induce tolerance in IgE-mediated allergy.

2009 | Journal article
DOI: 10.1615/CritRevImmunol.v29.i5.20
PMID: 20001887
Contributors: Baranyi U; Pilat N; Gattringer M; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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Bone marrow transplantation as a strategy for tolerance induction in the clinic.

2009 | Journal article
DOI: 10.2741/3267
PMID: 19273089
Contributors: Pree I; Pilat N; Wekerle T
Source: Self-asserted source
Nina Pilat via Europe PubMed Central
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