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Employment (4)

École Polytechnique Fédérale de Lausanne: Lausanne, VD, CH

2012-04-01 to present | Postdoctoral Research Associate (SV)
Employment
Source: Self-asserted source
Georgios Hatzopoulos

EPFL - École Polytechnique Fédérale de Lausanne: Lausanne, CH

2015 to 2025
Employment
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ORCID Integration at EPFL

EPFL - École Polytechnique Fédérale de Lausanne: Lausanne, CH

2015 to 2025 (School of Life Sciences, Swiss Institute for Experimental Cancer Research, Prof. Gönczy Group)
Employment
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ORCID Integration at EPFL

University of Oxford: Oxford, Oxfordshire, GB

2012-04-01 to 2015-03-31 | Postdoctoral Research Associate (Biochemistry Department)
Employment
Source: Self-asserted source
Georgios Hatzopoulos

Education and qualifications (2)

European Molecular Biology Laboratory: Hamburg, HH, DE

2005-04-01 to 2010-09-01 | PhD
Education
Source: Self-asserted source
Georgios Hatzopoulos

Democritus University of Thrace Department of Molecular Biology and Genetics: Alexandroupoli, GR

2000-10-01 to 2004-09-30 (Department of Molecular Biology and Genetics)
Education
Source: Self-asserted source
Georgios Hatzopoulos

Works (23)

Tubulin engineering by semi-synthesis reveals that polyglutamylation directs detyrosination

Nature Chemistry
2023-08 | Journal article
DOI: 10.1038/s41557-023-01228-8
Contributors: Eduard Ebberink; Simon Fernandes; Georgios Hatzopoulos; Ninad Agashe; Po-Han Chang; Nora Guidotti; Timothy M. Reichart; Luc Reymond; Marie-Claire Velluz; Fabian Schneider et al.
Source: check_circle
Crossref

CenFind: a deep-learning pipeline for efficient centriole detection in microscopy datasets.

BMC bioinformatics
2023-03 | Journal article
DOI: 10.1186/s12859-023-05214-2
PMID: 36977999
Contributors: Bürgy L; Weigert M; Hatzopoulos G; Minder M; Journé A; Rahi SJ; Gönczy P
Source: Self-asserted source
Georgios Hatzopoulos via Europe PubMed Central

The human cognition-enhancing CORD7 mutation increases active zone number and synaptic release

Brain
2022-11-21 | Journal article
DOI: 10.1093/brain/awac011
Contributors: Mila M Paul; Sven Dannhäuser; Lydia Morris; Achmed Mrestani; Martha Hübsch; Jennifer Gehring; Georgios N Hatzopoulos; Martin Pauli; Genevieve M Auger; Grit Bornschein et al.
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Crossref

Tubulin engineering by semisynthesis reveals that polyglutamylation directs detyrosination

2022-09 | Preprint
DOI: 10.1101/2022.09.20.508649
PPR: PPR547670
Contributors: Ebberink E; Fernandes S; Hatzopoulos G; Agashe N; Guidotti N; Reichart TM; Reymond L; Velluz M; Schneider F; Pourroy C et al.
Source: Self-asserted source
Georgios Hatzopoulos via Europe PubMed Central

Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel

Structure
2022-05 | Journal article
DOI: 10.1016/j.str.2022.02.005
Contributors: Anastassia L. Kantsadi; Georgios N. Hatzopoulos; Pierre Gönczy; Ioannis Vakonakis
Source: check_circle
Crossref

Kinetic and structural roles for the surface in guiding SAS-6 self-assembly to direct centriole architecture

Nature Communications
2021-10-26 | Journal article
DOI: 10.1038/s41467-021-26329-1
Contributors: Niccolò Banterle; Adrian P. Nievergelt; Svenja de Buhr; Georgios N. Hatzopoulos; Charlène Brillard; Santiago Andany; Tania Hübscher; Frieda A. Sorgenfrei; Ulrich S. Schwarz; Frauke Gräter et al.
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Crossref

Pulchelloid A, a sesquiterpene lactone from the Canadian prairie plant Gaillardia aristata inhibits mitosis in human cells.

Molecular biology reports
2021-07 | Journal article
DOI: 10.1007/s11033-021-06554-z
PMID: 34304367
Contributors: Bosco A; Molina L; Kernéis SM; Hatzopoulos G; Favez T; Gönczy P; Tantapakul C; Maneerat W; Yeremy B; Williams DE et al.
Source: Self-asserted source
Georgios Hatzopoulos via Europe PubMed Central

Tuning SAS-6 architecture with monobodies impairs distinct steps of centriole assembly

Nature Communications
2021-06-21 | Journal article
DOI: 10.1038/s41467-021-23897-0
Contributors: Georgios N. Hatzopoulos; Tim Kükenshöner; Niccolò Banterle; Tatiana Favez; Isabelle Flückiger; Virginie Hamel; Santiago Andany; Georg E. Fantner; Oliver Hantschel; Pierre Gönczy
Source: check_circle
Crossref

Novel features of centriole polarity and cartwheel stacking revealed by cryo‐tomography

The EMBO Journal
2020-11-16 | Journal article
DOI: 10.15252/embj.2020106249
Contributors: Sergey Nazarov; Alexandra Bezler; Georgios N Hatzopoulos; Veronika Nemčíková Villímová; Davide Demurtas; Maeva Le Guennec; Paul Guichard; Pierre Gönczy
Source: check_circle
Crossref

Surface-catalyzed SAS-6 self-assembly directs centriole formation through kinetic and structural mechanisms

2020-09-04 | Preprint
DOI: 10.1101/2020.09.04.283184
Contributors: Niccolò Banterle; Adrian P. Nievergelt; Svenja de Buhr; Georgios N. Hatzopoulos; Charlène Brillard; Santiago Andany; Tania Hübscher; Frieda Sorgenfrei; Ulrich S. Schwarz; Frauke Gräter et al.
Source: check_circle
Crossref

Novel features of centriole polarity and cartwheel stacking revealed by cryo-tomography

2020-07-18 | Preprint
DOI: 10.1101/2020.07.17.208082
Contributors: Sergey Nazarov; Alexandra Bezler; Georgios N Hatzopoulos; Veronika Nemčíková Villímová; Davide Demurtas; Maeva Le Guennec; Paul Guichard; Pierre Gönczy
Source: check_circle
Crossref

Centriole assembly at a glance

Journal of Cell Science
2019-02-15 | Journal article
DOI: 10.1242/jcs.228833
Part of ISSN: 1477-9137
Part of ISSN: 0021-9533
Contributors: Pierre Gonczy; Georgios N. Hatzopoulos
Source: Self-asserted source
Georgios Hatzopoulos

The Human Centriolar Protein CEP135 Contains a Two-Stranded Coiled-Coil Domain Critical for Microtubule Binding

Structure
2016-08 | Journal article
DOI: 10.1016/j.str.2016.06.011
Part of ISSN: 0969-2126
Contributors: Sebastian Kraatz; Paul Guichard; Jagan M. Obbineni; Natacha Olieric; Georgios N. Hatzopoulos; Manuel Hilbert; Indrani Sen; John Missimer; Pierre Gönczy; Michel O. Steinmetz
Source: Self-asserted source
Georgios Hatzopoulos

The centriolar protein CPAP G-box: an amyloid fibril in a single domain.

Biochemical Society transactions
2015-10 | Journal article
DOI: 10.1042/bst20150082
PMID: 26517891
PMC: PMC4613516
Contributors: Cutts EE; Inglis A; Stansfeld PJ; Vakonakis I; Hatzopoulos GN
Source: Self-asserted source
Georgios Hatzopoulos via Europe PubMed Central

The Caenorhabditis elegans protein SAS-5 forms large oligomeric assemblies critical for centriole formation

eLife
2015-05-29 | Journal article
DOI: 10.7554/elife.07410
Part of ISSN: 2050-084X
Contributors: Kacper B Rogala; Nicola J Dynes; Georgios N Hatzopoulos; Jun Yan; Sheng Kai Pong; Carol V Robinson; Charlotte M Deane; Pierre Gönczy; Ioannis Vakonakis
Source: Self-asserted source
Georgios Hatzopoulos

Structural Analysis of the G-Box Domain of the Microcephaly Protein CPAP Suggests a Role in Centriole Architecture

Structure
2013-11 | Journal article
DOI: 10.1016/j.str.2013.08.019
Part of ISSN: 0969-2126
Contributors: Georgios N. Hatzopoulos; Michèle C. Erat; Erin Cutts; Kacper B. Rogala; Leanne M. Slater; Philip J. Stansfeld; Ioannis Vakonakis
Source: Self-asserted source
Georgios Hatzopoulos

Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry

Proceedings of the National Academy of Sciences
2013-07-09 | Journal article
DOI: 10.1073/pnas.1302721110
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Contributors: Manuel Hilbert; Michèle C. Erat; Virginie Hachet; Paul Guichard; Iris D. Blank; Isabelle Flückiger; Leanne Slater; Edward D. Lowe; Georgios N. Hatzopoulos; Michel O. Steinmetz et al.
Source: Self-asserted source
Georgios Hatzopoulos

Structure of translation initiation factor 1 from Mycobacterium tuberculosis and inferred binding to the 30S ribosomal subunit.

FEBS letters
2010-02 | Journal article
DOI: 10.1016/j.febslet.2010.01.051
PMID: 20132820
Contributors: Hatzopoulos GN; Mueller-Dieckmann J
Source: Self-asserted source
Georgios Hatzopoulos via Europe PubMed Central

Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of interleukin-4-inducing principle from Schistosoma mansoni eggs (IPSE/alpha-1).

Acta crystallographica. Section F, Structural biology and crystallization communications
2009-05 | Journal article
DOI: 10.1107/s1744309109015899
PMID: 19478439
PMC: PMC2688418
Contributors: Mayerhofer H; Schramm G; Hatzopoulos GN; Mueller-Dieckmann C; Haas H; Mueller-Dieckmann J
Source: Self-asserted source
Georgios Hatzopoulos via Europe PubMed Central

Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of isocitrate dehydrogenase 2 (Rv0066c) from Mycobacterium tuberculosis.

Acta crystallographica. Section F, Structural biology and crystallization communications
2008-11 | Journal article
DOI: 10.1107/s1744309108035343
PMID: 19052369
PMC: PMC2593698
Contributors: Hatzopoulos GN; Kefala G; Mueller-Dieckmann J
Source: Self-asserted source
Georgios Hatzopoulos via Europe PubMed Central

Structural Basis for the Carbohydrate Recognition of the Sclerotium rolfsii Lectin

Journal of Molecular Biology
2007-05 | Journal article
DOI: 10.1016/j.jmb.2007.02.092
Part of ISSN: 0022-2836
Contributors: Demetres D. Leonidas; Bale M. Swamy; George N. Hatzopoulos; Sathisha J. Gonchigar; Vishwanath B. Chachadi; Shashikala R. Inamdar; Spyros E. Zographos; Nikos G. Oikonomakos
Source: Self-asserted source
Georgios Hatzopoulos

Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of initiation factor 1 from Mycobacterium tuberculosis.

Acta crystallographica. Section F, Structural biology and crystallization communications
2007-02 | Journal article
DOI: 10.1107/s174430910700437x
PMID: 17329809
PMC: PMC2330178
Contributors: Hatzopoulos GN; Mueller-Dieckmann J
Source: Self-asserted source
Georgios Hatzopoulos via Europe PubMed Central

The binding of IMP to ribonuclease A.

The FEBS journal
2005-08 | Journal article
DOI: 10.1111/j.1742-4658.2005.04822.x
PMID: 16045769
Contributors: Hatzopoulos GN; Leonidas DD; Kardakaris R; Kobe J; Oikonomakos NG
Source: Self-asserted source
Georgios Hatzopoulos via Europe PubMed Central

Peer review (2 reviews for 2 publications/grants)

Review activity for EMBO journal. (1)
Review activity for Review Commons (1)
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