Personal information

Activities

Employment (4)

Washington University in St. Louis: St Louis, US

2024-04-01 to present | Staff Scientist (Internal medicine)
Employment
Source: Self-asserted source
Astha Joshi

Washington University in St Louis School of Medicine: Saint Louis, MO, US

2019-04-15 to 2024-03-31 | Post Doc (Infectious Disease)
Employment
Source: Self-asserted source
Astha Joshi

International Institute of Molecular and Cell Biology in Warsaw: Warszawa, PL

2012-11-23 to 2018-09 | Ph.D. student (laboratory of Bioinformatics and Protein Engineering)
Employment
Source: Self-asserted source
Astha Joshi

Stanford University: Stanford, CA, US

2018-01-11 to 2018-06-30 | Visiting research scholar (Department of Biochemistry)
Employment
Source: Self-asserted source
Astha Joshi

Education and qualifications (3)

International Institute of Molecular and Cell Biology in Warsaw: Warszawa, PL

2012-11-23 to 2018-09 | Ph.D. (Laboratory of Bioinformatics and Protein Engineering)
Education
Source: Self-asserted source
Astha Joshi

Indian Institute of Technology Roorkee: Roorkee, Uttar Pradesh, IN

2010-08 to 2012-07 | M.Sc. Biotechnology (Department of Biotechnology)
Education
Source: Self-asserted source
Astha Joshi

Banaras Hindu University Faculty of Science: Varanasi, Uttar Pradesh, IN

2007-07 to 2010-05 | B.Sc. Chemistry(Hons.) (Faculty of Science)
Education
Source: Self-asserted source
Astha Joshi

Funding (1)

Structural RNomics

Grant
Narodowe Centrum Nauki (Krakow, PL)
Part of GRANT_NUMBER:

2012/04/A/NZ2/00455

GRANT_NUMBER:

2017/24/T/NZ1/00360

Source: Self-asserted source
Astha Joshi

Works (23)

Defining a highly conserved B cell epitope in the receptor binding motif of SARS-CoV-2 spike glycoprotein

2024-12-09 | Preprint
Contributors: Sameer Kumar Malladi; Deepika Jaiswal; Baoling Ying; Wafaa B. Alsoussi; Tamarand L. Darling; Bernadeta Dadonaite; Alesandro Civljak; Stephen C. Horvath; Julian Q. Zhou; Wooseob Kim et al.
Source: check_circle
Crossref

Mucosal immunization with ChAd-SARS-CoV-2-S prevents sequential transmission of SARS-CoV-2 to unvaccinated hamsters

Science Advances
2024-08-02 | Journal article
Contributors: Tamarand L. Darling; Houda H. Harastani; Astha Joshi; Traci L. Bricker; Nadia Soudani; Kuljeet Seehra; Ahmed O. Hassan; Michael S. Diamond; Adrianus C. M. Boon
Source: check_circle
Crossref

Vaccination reduces central nervous system IL-1β and memory deficits after COVID-19 in mice

Nature Immunology
2024-07 | Journal article
Part of ISSN: 1529-2908
Part of ISSN: 1529-2916
Contributors: Abigail Vanderheiden; Jeremy D. Hill; Xiaoping Jiang; Ben Deppen; Gayan Bamunuarachchi; Nadia Soudani; Astha Joshi; Matthew D. Cain; Adrianus Boon; Robyn S Klein
Source: Self-asserted source
Astha Joshi

Prototype and BA.5 protein nanoparticle vaccines protect against Omicron BA.5 variant in Syrian hamsters

Journal of Virology
2024-03-19 | Journal article
Part of ISSN: 0022-538X
Part of ISSN: 1098-5514
Contributors: Traci L. Bricker; Astha Joshi; Nadia Soudani; Suzanne M. Scheaffer; Nita Patel; Mimi Guebre-Xabier; Gale Smith; Michael S. Diamond; Adrianus Boon
Source: Self-asserted source
Astha Joshi

The Highly Conserved Stem-Loop II Motif Is Dispensable for SARS-CoV-2

Journal of Virology
2023-06-29 | Journal article
Part of ISSN: 0022-538X
Part of ISSN: 1098-5514
Contributors: Hongbing Jiang; Astha Joshi; Tianyu Gan; Andrew B Janowski; Chika Fujii; Traci L. Bricker; Tamarand L. Darling; Houda H. Harastani; Kuljeet Seehra; Hongwei Chen et al.
Source: Self-asserted source
Astha Joshi

Prevalence of Bourbon and Heartland viruses in field collected ticks at an environmental field station in St. Louis County, Missouri, USA

Ticks and Tick-borne Diseases
2023-01 | Journal article
Contributors: Ishmael D. Aziati; Derek McFarland Jnr; Avan Antia; Astha Joshi; Anahi Aviles-Gamboa; Preston Lee; Houda Harastani; David Wang; Solny A. Adalsteinsson; Adrianus C.M. Boon
Source: check_circle
Crossref

mRNA-1273 and Ad26.COV2.S Vaccines Protect Against the B.1.621 Variant of SARS-CoV-2

SSRN Electronic Journal
2022 | Journal article
Part of ISSN: 1556-5068
Source: Self-asserted source
Astha Joshi

Defining the risk of SARS-CoV-2 variants on immune protection

Nature
2022-03-31 | Journal article
Part of ISSN: 0028-0836
Part of ISSN: 1476-4687
Source: Self-asserted source
Astha Joshi

Prevalence of Bourbon and Heartland viruses in field collected ticks at an environmental field station in St. Louis County, Missouri, USA

2022-03-24 | Preprint
Contributors: Ishmael D Aziati; Derek McFarland; Avan Antia; Astha Joshi; Anahi Aviles-Gamboa; Preston Lee; Houda Harastani; David Wang; Solny A. Adalsteinsson; Adrianus C. M. Boon
Source: check_circle
Crossref

SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters

Nature
2022-03-24 | Journal article
Contributors: Peter J. Halfmann; Shun Iida; Kiyoko Iwatsuki-Horimoto; Tadashi Maemura; Maki Kiso; Suzanne M. Scheaffer; Tamarand L. Darling; Astha Joshi; Samantha Loeber; Gagandeep Singh et al.
Source: check_circle
Crossref

Egg-derived anti-SARS-CoV-2 immunoglobulin Y (IgY) with broad variant activity as intranasal prophylaxis against COVID-19

[]
2022-01-10 | Preprint
Source: Self-asserted source
Astha Joshi

The SARS-CoV-2 B.1.1.529 Omicron virus causes attenuated infection and disease in mice and hamsters

2021-12-29 | Preprint
Contributors: Michael Diamond; Peter Halfmann; Tadashi Maemura; Kiyoko Iwatsuki-Horimoto; Shun Iida; Maki Kiso; Suzanne Scheaffer; Tamarand Darling; Astha Joshi; Samantha Loeber et al.
Source: check_circle
Crossref

Computational Modeling Methods for 3D Structure Prediction of Ribozymes

Ribozymes
2021-09-14 | Book chapter
Part of ISBN: 9783527344543
Part of ISBN: 9783527814527
Source: Self-asserted source
Astha Joshi

Neutralizing Monoclonal Antibodies That Target the Spike Receptor Binding Domain Confer Fc Receptor-Independent Protection against SARS-CoV-2 Infection in Syrian Hamsters

mBio
2021-09-14 | Journal article
Part of ISSN: 2150-7511
Source: Self-asserted source
Astha Joshi

A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope

Immunity
2021-08 | Journal article
Part of ISSN: 1074-7613
Source: Self-asserted source
Astha Joshi

A vaccine-induced public antibody protects against SARS-CoV-2 and emerging variants

Immunity
2021-08-17 | Journal article
Part of ISSN: 1074-7613
Source: Self-asserted source
Astha Joshi
grade
Preferred source (of 2)‎

In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains

Nature
2021-08-05 | Journal article
Contributors: Rita E. Chen; Emma S. Winkler; James Brett Case; Ishmael D. Aziati; Traci L. Bricker; Astha Joshi; Tamarand L. Darling; Baoling Ying; John M. Errico; Swathi Shrihari et al.
Source: check_circle
Crossref

RNA-Puzzles Round IV: 3D structure predictions of four ribozymes and two aptamers

RNA
2020-08 | Journal article
Part of ISSN: 1355-8382
Part of ISSN: 1469-9001
Source: Self-asserted source
Astha Joshi

Computational modeling of RNA 3D structure based on experimental data

Bioscience Reports
2019-02-28 | Journal article
Contributors: Almudena Ponce-Salvatierra; Astha; Katarzyna Merdas; Chandran Nithin; Pritha Ghosh; Sunandan Mukherjee; Janusz M. Bujnicki
Source: check_circle
Crossref

RNArchitecture: A database and a classification system of RNA families, with a focus on structural information

Nucleic Acids Research
2018 | Journal article
EID:

2-s2.0-85040948693

Contributors: Boccaletto, P.; Magnus, M.; Almeida, C.; Żyła, A.; Astha, A.; Pluta, R.; Bagiński, B.; Jankowska, E.; Dunin-Horkawicz, S.; Wirecki, T.K. et al.
Source: Self-asserted source
Astha Joshi via Scopus - Elsevier

Human RNA cap1 methyltransferase CMTr1 cooperates with RNA helicase DHX15 to modify RNAs with highly structured 5′ termini

Philosophical Transactions of the Royal Society B: Biological Sciences
2018-12-19 | Journal article
Contributors: Diana Toczydlowska-Socha; Magdalena M. Zielinska; Malgorzata Kurkowska; Astha; Catarina F. Almeida; Filip Stefaniak; Elzbieta Purta; Janusz M. Bujnicki
Source: check_circle
Crossref

Impact of the structural integrity of the three-way junction of adenovirus VA<inf>I</inf>RNA on PKR inhibition

PLoS ONE
2017 | Journal article
EID:

2-s2.0-85031823599

Contributors: Dzananovic, E.; Astha; Chojnowski, G.; Deo, S.; Booy, E.P.; Padilla-Meier, P.; McEleney, K.; Bujnicki, J.M.; Patel, T.R.; McKenna, S.A.
Source: Self-asserted source
Astha Joshi via Scopus - Elsevier

Structural studies of RNA-protein complexes: A hybrid approach involving hydrodynamics, scattering, and computational methods

Methods
2017 | Journal article
EID:

2-s2.0-85008173938

Contributors: Patel, T.R.; Chojnowski, G.; Astha; Koul, A.; McKenna, S.A.; Bujnicki, J.M.
Source: Self-asserted source
Astha Joshi via Scopus - Elsevier

Peer review (2 reviews for 1 publication/grant)

Review activity for BMC research notes (2)