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Employment (1)

Washington University in St Louis: St Louis, MO, US

2021-02-01 to present | Postdoctoral Research Associate (Anesthesiology)
Employment
Source: Self-asserted source
John Smith Del Rosario

Education and qualifications (3)

Rutgers New Jersey Medical School: Newark, NJ, US

2014-08 to 2021-01 | Ph.D. in Biomedical Science (Pharmacology, Physiology and Neuroscience)
Education
Source: Self-asserted source
John Smith Del Rosario

City College of New York: New York, NY, US

2011-08 to 2014-06 | Master of Science (Biology)
Education
Source: Self-asserted source
John Smith Del Rosario

City College of New York: New York, NY, US

2007-08 to 2011-06 | Bachelor of Science (Biology )
Education
Source: Self-asserted source
John Smith Del Rosario

Funding (3)

Regulation of Piezo2 Channels by G-protein Coupled Receptors and Endocytosis

2019-09-01 to 2020-08-31 | Grant
National Institute of Neurological Disorders and Stroke (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.8633601
GRANT_NUMBER: F99NS113422
Source: Self-asserted source
John Smith Del Rosario via DimensionsWizard

Homeostatic Regulatory Mechanisms in Nociceptors

2019-08-01 to 2025-07-31 | Grant
National Institute of Neurological Disorders and Stroke (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.9843887
GRANT_NUMBER: K00NS113422
Source: Self-asserted source
John Smith Del Rosario via DimensionsWizard

Regulation of Piezo2 Channels by Ca2+ Sensitive Signaling Pathways and G-protein Coupled Receptors

2017-08-01 to 2020-01-31 | Grant
National Institute of Neurological Disorders and Stroke (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.7073124
GRANT_NUMBER: F31NS100484
Source: Self-asserted source
John Smith Del Rosario via DimensionsWizard

Works (16)

Intrinsic adaptive plasticity in mouse and human sensory neurons

Journal of General Physiology
2025-01-06 | Journal article
DOI: 10.1085/jgp.202313488
Contributors: Lisa A. McIlvried; John Smith Del Rosario; Melanie Y. Pullen; Andi Wangzhou; Tayler D. Sheahan; Andrew J. Shepherd; Richard A. Slivicki; John A. Lemen; Theodore J. Price; Bryan A. Copits et al.
Source: check_circle
Crossref

Bradykinin receptor expression and bradykinin-mediated sensitization of human sensory neurons

Pain
2023-09-13 | Journal article
DOI: 10.1097/j.pain.0000000000003013
Contributors: Jiwon Yi; Zachariah Bertels; John Smith Del Rosario; Allie J. Widman; Richard A. Slivicki; Maria Payne; Henry M. Susser; Bryan A. Copits; Robert W. Gereau
Source: check_circle
Crossref

Intrinsic Homeostatic Plasticity in Mouse and Human Sensory Neurons

2023-06-14 | Preprint
DOI: 10.1101/2023.06.13.544829
Contributors: Lisa A. McIlvried; John Smith Del Rosario; Melanie Y. Pullen; Andi Wangzhou; Tayler D. Sheahan; Andrew J. Shepherd; Richard A. Slivicki; John A. Lemen; Theodore J. Price; Bryan A. Copits et al.
Source: check_circle
Crossref

Bradykinin receptor expression and bradykinin-mediated sensitization of human sensory neurons

2023-04-01 | Preprint
DOI: 10.1101/2023.03.31.534820
Contributors: Jiwon Yi; Zachariah Bertels; John Smith Del Rosario; Allie J. Widman; Richard A. Slivicki; Maria Payne; Henry M. Susser; Bryan A. Copits; Robert W. Gereau, IV
Source: check_circle
Crossref

TMEM120A/TACAN inhibits mechanically activated PIEZO2 channels

Journal of General Physiology
2022-08-01 | Journal article
DOI: 10.1085/jgp.202213164
Contributors: John Smith Del Rosario; Matthew Gabrielle; Yevgen Yudin; Tibor Rohacs
Source: check_circle
Crossref

TMEM120A/TACAN inhibits mechanically activated Piezo2 channels

2021-06-30 | Other
DOI: 10.1101/2021.06.30.450616
Contributors: John Smith Del Rosario; Matthew Gabrielle; Yevgen Yudin; Tibor Rohacs
Source: check_circle
Crossref

Crowding-induced opening of the mechanosensitive Piezo1 channel in silico

Communications Biology
2021-01-19 | Journal article
DOI: 10.1038/s42003-020-01600-1
Contributors: Wenjuan Jiang; John Smith Del Rosario; Wesley Botello-Smith; Siyuan Zhao; Yi-chun Lin; Han Zhang; Jérôme Lacroix; Tibor Rohacs; Yun Lyna Luo
Source: check_circle
Crossref

Gi-coupled receptor activation potentiates Piezo2 currents via Gβγ.

EMBO reports
2020-03-29 | Journal article
DOI: 10.15252/embr.201949124
PMID: 32227462
Source: Self-asserted source
John Smith Del Rosario

A Piezo1 Open State Reveals a Multi-fenestrated Ion Permeation Pathway

2020-03-12 | Other
DOI: 10.1101/2020.03.12.988378
Contributors: Wenjuan Jiang; John Smith Del Rosario; Wesley Botello-Smith; Siyuan Zhao; Yi-chun Lin; Han Zhang; Jérôme Lacroix; Tibor Rohacs; Yun Lyna Luo
Source: check_circle
Crossref

Structure-based characterization of novel TRPV5 inhibitors

eLife
2019-10-25 | Journal article
DOI: 10.7554/eLife.49572
Contributors: Taylor ET Hughes; John Smith Del Rosario; Abhijeet Kapoor; Aysenur Torun Yazici; Yevgen Yudin; Edwin C Fluck, III; Marta Filizola; Tibor Rohacs; Vera Y Moiseenkova-Bell
Source: check_circle
Crossref

Gi-Coupled Receptor Activation Potentiates Piezo2 Currents via Gβγ

2019-08-02 | Other
DOI: 10.1101/722637
Source: Self-asserted source
John Smith Del Rosario
grade
Preferred source (of 2)‎

Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM.

Nature structural & molecular biology
2018-01-01 | Journal article
DOI: 10.1038/s41594-017-0009-1
PMID: 29323279
PMC: PMC5951624
Source: Self-asserted source
John Smith Del Rosario

Death Associated Protein Kinase (DAPK) -mediated neurodegenerative mechanisms in nematode excitotoxicity.

BMC neuroscience
2015-04-23 | Journal article
DOI: 10.1186/s12868-015-0158-2
PMID: 25899010
PMC: PMC4414438
Source: Self-asserted source
John Smith Del Rosario

The insulin/IGF signaling regulators cytohesin/GRP-1 and PIP5K/PPK-1 modulate susceptibility to excitotoxicity in C. elegans.

PloS one
2014-11-25 | Journal article
DOI: 10.1371/journal.pone.0113060
PMID: 25422944
PMC: PMC4244091
Source: Self-asserted source
John Smith Del Rosario

Tumor necrosis factor-α inhibitors alleviation of experimentally induced neuropathic pain is associated with modulation of TNF receptor expression.

Journal of neuroscience research
2014-06-25 | Journal article
DOI: 10.1002/jnr.23432
PMID: 24964368
Source: Self-asserted source
John Smith Del Rosario

The thalidomide analgesic effect is associated with differential TNF-α receptor expression in the dorsal horn of the spinal cord as studied in a rat model of neuropathic pain.

Brain research
2012-02-22 | Journal article
DOI: 10.1016/j.brainres.2012.02.033
PMID: 22425187
Source: Self-asserted source
John Smith Del Rosario
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