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Employment (2)

Hebrew University Faculty of Medicine: Jerusalem, Jerusalem, IL

2009-03-01 to present | Associate professor (Biochemistry and Molecular Biology)
Employment
Source: Self-asserted source
Ehud Cohen

The Hebrew University of Jerusalem: Jerusalem, IL

2009-01-01 to present (Faculty of Medicine)
Employment
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The Hebrew University of Jerusalem

Education and qualifications (2)

Salk Institute for Biological Studies: La Jolla, CA, US

2004-03-01 to 2009 | Post-doctoral fellow (Molecular Cell Biology)
Education
Source: Self-asserted source
Ehud Cohen

Hebrew University of Jerusalem Faculty of Medicine: Jerusalem, Jerusalem, IL

1998-04-02 to 2004-03-20 | PhD (Cell Biology)
Education
Source: Self-asserted source
Ehud Cohen

Funding (1)

Dissecting the roles of caveolae as a regulator aging and proteotoxicity

2016-10 to 2019-09 | Grant
Israel Science Foundation (Jerusalem, IL)
GRANT_NUMBER:

981/16
Source: Self-asserted source
Ehud Cohen

Works (35)

Gene expression modulation by the linker of nucleoskeleton and cytoskeleton complex contributes to proteostasis

Aging Cell
2019-12 | Journal article
DOI: 10.1111/acel.13047
Part of ISSN: 1474-9718
Part of ISSN: 1474-9726
Source: Self-asserted source
Ehud Cohen

Lipid Assemblies at the Crossroads of Aging, Proteostasis, and Neurodegeneration

Trends in Cell Biology
2019-12 | Journal article
DOI: 10.1016/j.tcb.2019.09.003
Part of ISSN: 0962-8924
Source: Self-asserted source
Ehud Cohen

The insulin/IGF signaling cascade modulates SUMOylation to regulate aging and proteostasis in Caenorhabditis elegans

eLife
2018-11-07 | Journal article
DOI: 10.7554/elife.38635
Part of ISSN: 2050-084X
Source: Self-asserted source
Ehud Cohen

Modulation of caveolae by insulin/ IGF ‐1 signaling regulates aging of Caenorhabditis elegans

EMBO reports
2018-08 | Journal article
DOI: 10.15252/embr.201745673
Part of ISSN: 1469-221X
Part of ISSN: 1469-3178
Source: Self-asserted source
Ehud Cohen

Vesicle-mediated secretion of misfolded prion protein molecules from cyclosporin A-treated cells.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
2018-03 | Journal article
DOI: 10.1096/fj.201700598rrr
PMID: 29127190
Contributors: Pan I; Roitenberg N; Cohen E
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

The Emerging Roles of Early Protein Folding Events in the Secretory Pathway in the Development of Neurodegenerative Maladies.

Frontiers in neuroscience
2017 | Journal article
DOI: 10.3389/fnins.2017.00048
PMID: 28223916
PMC: PMC5293786
Contributors: Dubnikov T; Cohen E
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

A multi-animal tracker for studying complex behaviors.

BMC biology
2017-04 | Journal article
DOI: 10.1186/s12915-017-0363-9
PMID: 28385158
PMC: PMC5383998
Contributors: Itskovits E; Levine A; Cohen E; Zaslaver A
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

Protein Quality Control in Health and Disease.

2016-11 | Journal article
DOI: 10.1101/cshperspect.a023523
PMID: 27864315
Contributors: Dubnikov T; Ben-Gedalya T; Cohen E
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

PrP-containing aggresomes are cytosolic components of an ER quality control mechanism.

2016-10 | Journal article
DOI: 10.1242/jcs.186981
PMID: 27550517
Contributors: Dubnikov T; Ben-Gedalya T; Reiner R; Hoepfner D; Cabral WA; Marini JC; Cohen E
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

The inhibition of IGF-1 signaling promotes proteostasis by enhancing protein aggregation and deposition.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
2016-04 | Journal article
DOI: 10.1096/fj.15-281675
PMID: 26722006
Contributors: Moll L; Ben-Gedalya T; Reuveni H; Cohen E
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

From mutated genes to familial Alzheimer's disease

Cell Cycle
2016-03-03 | Journal article
DOI: 10.1080/15384101.2016.1151727
Contributors: Tziona Ben-Gedalya; Ehud Cohen
Source: Self-asserted source
Ehud Cohen via Crossref Metadata Search

The roles of cellular and organismal aging in the development of late-onset maladies.

2015 | Journal article
DOI: 10.1146/annurev-pathol-012414-040508
PMID: 25340639
Contributors: Carvalhal Marques F; Volovik Y; Cohen E
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

The inhibition of IGF-1 signaling promotes proteostasis by enhancing protein aggregation and deposition.

The FASEB journal
2015-12-31 | Journal article
Source: Self-asserted source
Ehud Cohen

Alzheimer's disease-causing proline substitutions lead to presenilin 1 aggregation and malfunction.

2015-11 | Journal article
DOI: 10.15252/embj.201592042
PMID: 26438723
PMC: PMC4682640
Contributors: Ben-Gedalya T; Moll L; Bejerano-Sagie M; Frere S; Cabral WA; Friedmann-Morvinski D; Slutsky I; Burstyn-Cohen T; Marini JC; Cohen E
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

Proteostasis collapse, inter-tissue communication, and the regulation of aging at the organismal level

Frontiers in Genetics
2015-03-05 | Journal article
DOI: 10.3389/fgene.2015.00080
Contributors: Tatyana Dubnikov; Ehud Cohen
Source: Self-asserted source
Ehud Cohen via Crossref Metadata Search

Selective manipulation of aging: a novel strategy for the treatment of neurodegenerative disorders.

2014 | Journal article
DOI: 10.4414/smw.2014.13917
PMID: 24526357
Contributors: Moll L; El-Ami T; Cohen E
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

Differential regulation of the heat shock factor 1 and DAF-16 by neuronal nhl-1 in the nematode C. elegans.

2014-12 | Journal article
DOI: 10.1016/j.celrep.2014.11.028
PMID: 25497098
Contributors: Volovik Y; Moll L; Marques FC; Maman M; Bejerano-Sagie M; Cohen E
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

The nematode Caenorhabditis elegans: a versatile model for the study of proteotoxicity and aging.

2014-08 | Journal article
DOI: 10.1016/j.ymeth.2014.04.014
PMID: 24794346
Contributors: Volovik Y; Marques FC; Cohen E
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

A novel inhibitor of the insulin/IGF signaling pathway protects from age-onset, neurodegeneration-linked proteotoxicity.

2014-02 | Journal article
DOI: 10.1111/acel.12171
PMID: 24261972
PMC: PMC4326862
Contributors: El-Ami T; Moll L; Carvalhal Marques F; Volovik Y; Reuveni H; Cohen E
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

A neuronal GPCR is critical for the induction of the heat shock response in the nematode C. elegans.

2013-04 | Journal article
DOI: 10.1523/jneurosci.4023-12.2013
PMID: 23554491
Contributors: Maman M; Carvalhal Marques F; Volovik Y; Dubnikov T; Bejerano-Sagie M; Cohen E
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

Aging, Protein Aggregation, Chaperones and Neurodegenerative Disorders: Mechanisms of Coupling and Therapeutic Opportunities

Rambam Maimonides Medical Journal
2012-10 | Journal article
DOI: 10.5041/rmmj.10088
Contributors: Ehud Cohen
Source: Self-asserted source
Ehud Cohen via Crossref Metadata Search

Temporal requirements of heat shock factor-1 for longevity assurance.

2012-06 | Journal article
DOI: 10.1111/j.1474-9726.2012.00811.x
PMID: 22360389
PMC: PMC4349560
Contributors: Volovik Y; Maman M; Dubnikov T; Bejerano-Sagie M; Joyce D; Kapernick EA; Cohen E; Dillin A
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

Quality Control Compartments Coming of Age

Traffic
2012-02 | Journal article
DOI: 10.1111/j.1600-0854.2012.01330.x
Contributors: Tziona Ben-Gedalya; Ehud Cohen
Source: Self-asserted source
Ehud Cohen via Crossref Metadata Search

Countering neurodegeneration by reducing the activity of the insulin/IGF signaling pathway: current knowledge and future prospects.

2011 | Journal article
DOI: 10.1016/j.exger.2010.08.032
PMID: 20849948
Contributors: Cohen E
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

Cyclosporin-A-induced prion protein aggresomes are dynamic quality-control cellular compartments.

2011-06 | Journal article
DOI: 10.1242/jcs.077693
PMID: 21558416
Contributors: Ben-Gedalya T; Lyakhovetsky R; Yedidia Y; Bejerano-Sagie M; Kogan NM; Karpuj MV; Kaganovich D; Cohen E
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

A kinetic aggregation assay allowing selective and sensitive amyloid-β quantification in cells and tissues.

2011-03 | Journal article
DOI: 10.1021/bi1013744
PMID: 21268584
PMC: PMC3051019
Contributors: Du D; Murray AN; Cohen E; Kim HE; Simkovsky R; Dillin A; Kelly JW
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

Ageing and protein aggregation-mediated disorders: from invertebrates to mammals.

2011-01 | Journal article
DOI: 10.1098/rstb.2010.0271
PMID: 21115535
PMC: PMC3001306
Contributors: Dillin A; Cohen E
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

Temporal requirements of insulin/IGF-1 signaling for proteotoxicity protection.

2010-04 | Journal article
DOI: 10.1111/j.1474-9726.2009.00541.x
PMID: 20003171
PMC: PMC3026833
Contributors: Cohen E; Du D; Joyce D; Kapernick EA; Volovik Y; Kelly JW; Dillin A
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

Reduced IGF-1 signaling delays age-associated proteotoxicity in mice.

2009-12 | Journal article
DOI: 10.1016/j.cell.2009.11.014
PMID: 20005808
PMC: PMC3017511
Contributors: Cohen E; Paulsson JF; Blinder P; Burstyn-Cohen T; Du D; Estepa G; Adame A; Pham HM; Holzenberger M; Kelly JW et al.
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

A kinetic assessment of the C. elegans amyloid disaggregation activity enables uncoupling of disassembly and proteolysis.

2009-11 | Journal article
DOI: 10.1002/pro.234
PMID: 19701939
PMC: PMC2788278
Contributors: Bieschke J; Cohen E; Murray A; Dillin A; Kelly JW
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

The insulin paradox: aging, proteotoxicity and neurodegeneration.

2008-10 | Journal article
DOI: 10.1038/nrn2474
PMID: 18769445
PMC: PMC2692886
Contributors: Cohen E; Dillin A
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

Opposing activities protect against age-onset proteotoxicity.

Science (New York, N.Y.)
2006-09 | Journal article
DOI: 10.1126/science.1124646
PMID: 16902091
Contributors: Cohen E; Bieschke J; Perciavalle RM; Kelly JW; Dillin A
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

Scrapie-like prion protein accumulates in aggresomes of cyclosporin A-treated cells.

2003-02 | Journal article
DOI: 10.1093/emboj/cdg045
PMID: 12554642
PMC: PMC140730
Contributors: Cohen E; Taraboulos A
Source: Self-asserted source
Ehud Cohen via Europe PubMed Central

Modulation of caveolae by insulin/IGF-1 signaling regulates aging of Caenorhabditis elegans.

Journal article
PMID: 29945933
Source: Self-asserted source
Ehud Cohen

The Insulin/IGF signaling cascade modulates SUMOylation to regulate aging and proteostasis in C. elegans

Journal article
PMID: 30403374
Source: Self-asserted source
Ehud Cohen
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