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Employment (1)

Research Center for Molecular Medicine of the Austrian Academy of Sciences: Vienna, Wien, AT

2016-06-27 to present
Employment
Source: Self-asserted source
Georg Winter

Education and qualifications (2)

Dana Farber Cancer Institute: Boston, MA, US

2013-06-01 to 2016-06-07
Education
Source: Self-asserted source
Georg Winter

Research Center for Molecular Medicine of the Austrian Academy of Sciences: Vienna, Wien, AT

2008-09-27 to 2013-05-20
Education
Source: Self-asserted source
Georg Winter

Funding (1)

Chaser

2013 to 2015 | Salary award
European Molecular Biology Organization (Heidelberg, DE)
Source: Self-asserted source
Georg Winter

Works (22)

Leveraging Dual-Ligase Recruitment to Enhance Protein Degradation via a Heterotrivalent Proteolysis Targeting Chimera

Journal of the American Chemical Society
2024-12-11 | Journal article
DOI: 10.1021/jacs.4c11556
Contributors: Adam G. Bond; Miquel Muñoz i Ordoño; Celia M. Bisbach; Conner Craigon; Nikolai Makukhin; Elizabeth A. Caine; Manjula Nagala; Marjeta Urh; Georg E. Winter; Kristin M. Riching et al.
Source: check_circle
Crossref

Extrapolating Lessons from Targeted Protein Degradation to Other Proximity-Inducing Drugs

ACS Chemical Biology
2024-10-18 | Journal article
DOI: 10.1021/acschembio.4c00191
Contributors: Georg E. Winter
Source: check_circle
Crossref

Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype

Nature Communications
2023-11-30 | Journal article
DOI: 10.1038/s41467-023-43657-6
Contributors: Gang Xue; Jianing Xie; Matthias Hinterndorfer; Marko Cigler; Lara Dötsch; Hana Imrichova; Philipp Lampe; Xiufen Cheng; Soheila Rezaei Adariani; Georg E. Winter et al.
Source: check_circle
Crossref

Advancing Targeted Protein Degradation via Multiomics Profiling and Artificial Intelligence

Journal of the American Chemical Society
2023-02-08 | Journal article
DOI: 10.1021/jacs.2c11098
Contributors: Miquel Duran-Frigola; Marko Cigler; Georg E. Winter
Source: check_circle
Crossref

CIDE-stepping E3s

Nature Chemical Biology
2023-01 | Journal article
DOI: 10.1038/s41589-022-01217-x
Contributors: Gary Tin; Georg E. Winter
Source: check_circle
Crossref

The 2nd Alpine Winter Conference on Medicinal and Synthetic Chemistry

ChemMedChem
2021-08-05 | Journal article
DOI: 10.1002/cmdc.202100372
Contributors: Alessio Ciulli; Lawrence Hamann; Wolfgang Jahnke; Amit S. Kalgutkar; Thomas Magauer; Tobias Ritter; Vicky Steadman; Scott D. Williams; Georg Winter; Klemens Hoegenauer et al.
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Crossref

Identification and characterization of cancer vulnerabilities via targeted protein degradation

Drug Discovery Today: Technologies
2019-04 | Journal article
DOI: 10.1016/j.ddtec.2018.12.003
Contributors: Cristina Mayor-Ruiz; Georg E. Winter
Source: check_circle
Crossref

Target interaction profiling of midostaurin and its metabolites in neoplastic mast cells predicts distinct effects on activation and growth

Leukemia
2016 | Journal article
Source: Self-asserted source
Georg Winter

Human haploid cell genetics reveals roles for lipid metabolism genes in nonapoptotic cell death

ACS chemical biology
2015 | Journal article
Source: Self-asserted source
Georg Winter

Phthalimide conjugation as a strategy for in vivo target protein degradation

Science
2015 | Journal article
Source: Self-asserted source
Georg Winter

The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation

Journal of cellular physiology
2015 | Journal article
Source: Self-asserted source
Georg Winter

A chemical biology approach identifies AMPK as a modulator of melanoma oncogene MITF

Oncogene
2014 | Journal article
Source: Self-asserted source
Georg Winter

Suv39h-dependent H3K9me3 marks intact retrotransposons and silences LINE elements in mouse embryonic stem cells

Molecular cell
2014 | Journal article
Source: Self-asserted source
Georg Winter

The solute carrier SLC35F2 enables YM155-mediated DNA damage toxicity

Nature chemical biology
2014 | Journal article
Source: Self-asserted source
Georg Winter

Elucidating the molecular mechanism of action of cancer drugs in the second decade of the new millennium

Experimental Hematology
2013 | Journal article
Source: Self-asserted source
Georg Winter

Evaluation of the effects of the PKC412-metabolites CGP52421 and CGP62221 on proliferation and viability of neoplastic mast cells and IgE dependent secretion of histamine

ONKOLOGIE
2013 | Conference paper
Source: Self-asserted source
Georg Winter

Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms

Molecular systems biology
2013 | Journal article
Source: Self-asserted source
Georg Winter

P051 Mapping the TNF-induced necroptosis pathway by experimental test-tube genetics in human haploid cells

Cytokine
2012 | Journal article
Source: Self-asserted source
Georg Winter

Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML

Nature chemical biology
2012 | Journal article
Source: Self-asserted source
Georg Winter

Target/s Identification Approaches--Experimental Biological Approaches

Designing Multi-Target Drugs
2012 | Journal article
Source: Self-asserted source
Georg Winter

An integrated chemical biology approach identifies specific vulnerability of Ewing's sarcoma to combined inhibition of Aurora kinases A and B

Molecular cancer therapeutics
2011 | Journal article
Source: Self-asserted source
Georg Winter

MASPECTRAS 2: An integration and analysis platform for proteomic data

Proteomics
2010 | Journal article
Source: Self-asserted source
Georg Winter

Peer review (16 reviews for 9 publications/grants)

Review activity for ACS central science. (1)
Review activity for ACS chemical biology. (2)
Review activity for Cell chemical biology. (2)
Review activity for Journal of medicinal chemistry. (3)
Review activity for Journal of the American Chemical Society. (3)
Review activity for Nature (1)
Review activity for Nature chemical biology. (1)
Review activity for Nature communications (2)
Review activity for Nature structural & molecular biology. (1)
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