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Works (15)

DESIGN, CHEMICAL SYNTHESIS, AND IN VITRO  EVALUATION OF NOVEL UNCHARGED CHOLINESTERASE REACTIVATOR

Military Medical Science Letters
2024-09-18 | Journal article
DOI: 10.31482/mmsl.2024.015
Contributors: Vendula Hepnarova; Martina Hrabinova; Jakub Opravil; Mojmir Vanek; Eva Mezeiova; Lukas Gorecki; Tomas Kucera; Daniel Jun; Ondrej Soukup; Lubica Muckova et al.
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IN SILICO LIBRARY SCREENING TO FIND NOVEL ANTICANCER AGENT WITH CHEMOSENSITIZING PROPERTIES: FOCUS ON TARGETING ATAXIA TELANGIECTASIA AND Rad3 RELATED KINASE

Military Medical Science Letters
2024-03-01 | Journal article
DOI: 10.31482/mmsl.2023.009
Contributors: Darina Muthna; Tomas Kucera; Zbynek Vecera; Lukas Gorecki; Martin Andrs; Martina Rezacova; Jan Korabecny
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Amaryllidaceae Alkaloids of Norbelladine-Type as Inspiration for Development of Highly Selective Butyrylcholinesterase Inhibitors: Synthesis, Biological Activity Evaluation, and Docking Studies

International Journal of Molecular Sciences
2021-08-02 | Journal article
DOI: 10.3390/ijms22158308
Contributors: Abdullah Al Mamun; Filip Pidaný; Daniela Hulcová; Jana Maříková; Tomáš Kučera; Monika Schmidt; Maria Carmen Catapano; Martina Hrabinová; Daniel Jun; Lubica Múčková et al.
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IMPLEMENTATION OF DISTANCE LEARNING INTO EDUCATION OF THE DEPARTMENT OF MILITARY MEDICAL SERVICE ORGANIZATION AND MANAGEMENT OF THE UNIVERSITY OF DEFENCE UNDER THE COVID-19 PANDEMIC CONDITIONS

Military Medical Science Letters
2021-06-04 | Journal article
DOI: 10.31482/mmsl.2021.009
Contributors: Milan Růžička; Pavel Blažek; Jaroslav Žďára; Tomáš Kučera; Vojtěch Humlíček; Hynek Schvach; Zbyněk Suchánek; Petr Smola; Dana Knajflová
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Synthesis of New Biscoumarin Derivatives, In Vitro Cholinesterase Inhibition, Molecular Modelling and Antiproliferative Effect in A549 Human Lung Carcinoma Cells

International Journal of Molecular Sciences
2021-04 | Journal article | Author
DOI: 10.3390/ijms22083830
Contributors: Monika Hudáčová; Slavka Hamulakova; Eva Žilecká; Rastislav Jendželovský; Jana Vargova; Juraj Ševc; Peter Fedorocko; Ondrej Soukup; Jana Janočková; Veronika Ihnatova et al.
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Multidisciplinary Digital Publishing Institute

Structure–Activity Relationship Study of Dexrazoxane Analogues Reveals ICRF-193 as the Most Potent Bisdioxopiperazine against Anthracycline Toxicity to Cardiomyocytes Due to Its Strong Topoisomerase IIβ Interactions

Journal of Medicinal Chemistry
2021-04-08 | Journal article
DOI: 10.1021/acs.jmedchem.0c02157
Contributors: Anna Jirkovská; Galina Karabanovich; Jan Kubeš; Veronika Skalická; Iuliia Melnikova; Jan Korábečný; Tomáš Kučera; Eduard Jirkovský; Lucie Nováková; Hana Bavlovič Piskáčková et al.
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Structure Elucidation and Cholinesterase Inhibition Activity of Two New Minor Amaryllidaceae Alkaloids

Molecules
2021-02-26 | Journal article
DOI: 10.3390/molecules26051279
Contributors: Jana Maříková; Abdullah Al Mamun; Latifah Al Shammari; Jan Korábečný; Tomáš Kučera; Daniela Hulcová; Jiří Kuneš; Milan Malaník; Michaela Vašková; Eliška Kohelová et al.
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Pursuing the Complexity of Alzheimer’s Disease: Discovery of Fluoren-9-Amines as Selective Butyrylcholinesterase Inhibitors and N-Methyl-d-Aspartate Receptor Antagonists

Biomolecules
2020-12-22 | Journal article
DOI: 10.3390/biom11010003
Contributors: Jan Konecny; Anna Misiachna; Martina Hrabinova; Lenka Pulkrabkova; Marketa Benkova; Lukas Prchal; Tomas Kucera; Tereza Kobrlova; Vladimir Finger; Marharyta Kolcheva et al.
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Enzymatic Degradation of Organophosphorus Pesticides and Nerve Agents by EC: 3.1.8.2

Catalysts
2020-11-24 | Journal article
DOI: 10.3390/catal10121365
Contributors: Marek Matula; Tomas Kucera; Ondrej Soukup; Jaroslav Pejchal
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Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile

European Journal of Medicinal Chemistry
2020-10 | Journal article
DOI: 10.1016/j.ejmech.2020.112593
Contributors: Katerina Sobolova; Martina Hrabinova; Vendula Hepnarova; Tomas Kucera; Tereza Kobrlova; Marketa Benkova; Jana Janockova; Rafael Dolezal; Lukas Prchal; Ondrej Benek et al.
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Interaction of Cucurbit[7]uril with Oxime K027, Atropine, and Paraoxon: Risky or Advantageous Delivery System?

International Journal of Molecular Sciences
2020-10-23 | Journal article
DOI: 10.3390/ijms21217883
Contributors: Jana Zdarova Karasova; Martin Mzik; Tomas Kucera; Zbynek Vecera; Jiri Kassa; Vit Sestak
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SEARCHING FOR NEW ANTIMICROBIAL AGENTS BY TARGETING BACTERIAL NAD METABOLISM: EVALUATION OF FRENTIZOLE DERIVATIVES SELECTED BY MOLECULAR DOCKING

Military Medical Science Letters
2020-06-05 | Journal article
DOI: 10.31482/mmsl.2020.005
Contributors: Michaela Hympanova; Tomas Kucera; Ondrej Benek; Jan Korabecny; Jan Marek
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Derivatives of the β-Crinane Amaryllidaceae Alkaloid Haemanthamine as Multi-Target Directed Ligands for Alzheimer’s Disease

Molecules
2019-04 | Journal article | Author
DOI: 10.3390/molecules24071307
Contributors: Eliška Kohelová; Rozálie Peřinová; Negar Maafi; Jan Korabecny; Daniela Hulcová; Jana Maříková; Tomas Kucera; Loreto Martínez González; Martina Hrabinova; Katarina Svrckova et al.
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Multidisciplinary Digital Publishing Institute
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In Vitro and In Silico Acetylcholinesterase Inhibitory Activity of Thalictricavine and Canadine and Their Predicted Penetration across the Blood-Brain Barrier

Molecules
2019-04 | Journal article | Author
DOI: 10.3390/molecules24071340
Contributors: Jakub Chlebek; Jan Korabecny; Rafael Doležal; Šárka Štěpánková; Daniel I. Pérez; Anna Hostalkova; Lubomír Opletal; Lucie Cahlíková; Kateřina Macáková; Tomas Kucera et al.
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Multidisciplinary Digital Publishing Institute
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VIRTUAL SCREENING IN DRUG DESIGN - OVERVIEW OF MOST FREQUENT TECHNIQUES

Military Medical Science Letters
2016-06-14 | Journal article
DOI: 10.31482/mmsl.2016.014
Contributors: Tomáš Kučera
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Peer review (2 reviews for 1 publication/grant)

Review activity for Molecules. (2)
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