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Other IDs

Scopus Author ID: 57200298230

Keywords

Cell Biology, Neuroscience, Alzheimer's disease, Neuroinflammation, Tau pathology

Countries

Spain

Biography

Ph.D. in Cell and Molecular Biology, Bachelor's degree in Biology and Master's degree in Cell and Molecular Biology by the University of Malaga. Since 2012 working in Alzheimer's disease and other brain-related disorders at the University of Malaga (Spain) in a laboratory of recognized prestige in Neuroscience. This lab is focused on understanding the pathogenic mechanisms involved in the synaptic and neuronal loss, but especially interested in the role of the neuroinflammatory response in the development/progression of Alzheimer's disease. Other goals are to identify potential biomarkers and therapeutic targets and evaluate the effectiveness of new therapeutic strategies at the preclinical level. I do research in Alzheimer's disease, Frontotemporal Dementia and other tauopathies, through behavior analysis (MWM, NOR, OLT, Y/T maze), histochemical (IHC, ICC, IF) and molecular techniques (WB, PCR).

Activities

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Employment (7)

Universidad de Málaga: Málaga, ES

2023-11-17 to present | Lecturer (Developmental Psychology )
Employment
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela

FIMABIS: Malaga, ES

2022-05-17 to 2023-11-16 | Postdoc Junior (Department of Cell Biology, Genetics and Physiology)
Employment
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela

University of Malaga: Málaga, ES

2022-03-01 to 2022-05-15 | Postdoctoral Researcher (Cell Biology, Genetics and Physiology)
Employment
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela

University of Malaga: Málaga, ES

2020-12-15 to 2022-03-01 | Research assistant (Cell Biology, Genetics and Physiology)
Employment
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela

University of Malaga: Málaga, ES

2020-01-15 to 2020-12-14 | Postdoctoral fellow (Cell Biology, Genetics and Physiology)
Employment
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela

University of Malaga: Málaga, ES

2019-10-14 to 2020-01-13 | Research assistant (Cell Biology, Genetics and Physiology)
Employment
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela

University of Malaga: Málaga, ES

2015-01-01 to 2019-09-17 | PhD Student (FPU fellowship) (Cell Biology, Genetics and Physiology)
Employment
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela

Education and qualifications (3)

University of Malaga: Málaga, ES

2015-09-17 to 2020-12-03 | PhD in Cellular and Molecular Biology (Cell Biology)
Education
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela

University of Malaga: Málaga, ES

2014-10-24 to 2015-07-09 | Master's degree in Cell and Molecular Biology (Cell Biology, Genetics and Physiology)
Qualification
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela

University of Malaga: Málaga, ES

2009-09-28 to 2014-07-15 | Bachelor's degree in Biology (Cell Biology, Genetics and Physiology)
Education
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela

Professional activities (2)

Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas: Madrid, Madrid, ES

2015-10-01 to present | Researcher in CBO6/05/1116 group
Membership
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela

Instituto de Investigación Biomédica de Málaga: Málaga, ES

2015-09-01 to present | Researcher in NeuroAD group (Cell Biology, Genetics and Physiology (Faculty of Science, University of Malaga))
Membership
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela

Funding (4)

Elucidating the role of Trem2 in the microglial response against tau pathology: searching for new therapeutic targets

2022-05 to 2023-11 | Contract
Consejería de Salud y Familias, Junta de Andalucía (Malaga, ES)
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela

Evaluating the contribution of glial response to the progression of amyloid and tau pathologies in AD transgenic mice

2020-01 to 2020-12 | Contract
University of Malaga (Málaga, ES)
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela

Effect of aging in the microglia and astroglia response to pathological forms of tau in vivo and in vitro tauopathy models

2017-05 to 2020-08 | Award
University of Malaga (Málaga, ES)
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela

Differential contribution of toxic Abeta and tau species to the degenerative process in Alzheimer's disease: searching for new therapeutic targets

2015-09 to 2019-09 | Contract
MINISTERIO DE EDUCACIÓN, CULTURA Y DEPORTE (Malaga, ES)
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela

Works (9)

Monocyte-derived cells invade brain parenchyma and amyloid plaques in human Alzheimer’s disease hippocampus

Acta Neuropathologica Communications
2023-02-28 | Journal article
DOI: 10.1186/s40478-023-01530-z
Part of ISSN: 2051-5960
Contributors: Clara Muñoz-Castro; Marina Mejias-Ortega; Elisabeth Sanchez-Mejias; Victoria Navarro; Laura Trujillo-Estrada; Sebastian Jimenez; Juan Antonio Garcia-Leon; Juan Jose Fernandez-Valenzuela; Maria Virtudes Sanchez-Mico; Carmen Romero-Molina et al.
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela

Longitudinal Assessment of Tau-Associated Pathology by 18F-THK5351 PET Imaging: A Histological, Biochemical, and Behavioral Study

Diagnostics
2021-10-12 | Journal article
DOI: 10.3390/diagnostics11101874
Part of ISSN: 2075-4418
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela

COLLABORATIVE WORKING IN A VIRTUAL ENGINEERING LABORATORY

2021-03 | Conference paper
DOI: 10.21125/inted.2021.1677
Contributors: Maria Villen-Guzman; Raquel Maria Sanchez-Varo; Maria Del Mar Cerrillo-Gonzalez; Juan Jose Fernandez-Valenzuela; J.M. Rodriguez-Maroto; Juan Manuel Paz-Garcia
Source: check_circle
Crossref

Distinct disease-sensitive GABAergic neurons in the perirhinal cortex of Alzheimer's mice and patients

Brain Pathology
2020 | Journal article
DOI: 10.1111/bpa.12785
EID:

2-s2.0-85074042592

Part of ISBN:

17503639 10156305
Contributors: Sanchez-Mejias, E.; Nuñez-Diaz, C.; Sanchez-Varo, R.; Gomez-Arboledas, A.; Garcia-Leon, J.A.; Fernandez-Valenzuela, J.J.; Mejias-Ortega, M.; Trujillo-Estrada, L.; Baglietto-Vargas, D.; Moreno-Gonzalez, I. et al.
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela via Scopus - Elsevier

Enhancing microtubule stabilization rescues cognitive deficits and ameliorates pathological phenotype in an amyloidogenic Alzheimer’s disease model

Scientific Reports
2020 | Journal article
DOI: 10.1038/s41598-020-71767-4
EID:

2-s2.0-85090328424

Part of ISBN:

20452322
Contributors: Fernandez-Valenzuela, J.J.; Sanchez-Varo, R.; Muñoz-Castro, C.; De Castro, V.; Sanchez-Mejias, E.; Navarro, V.; Jimenez, S.; Nuñez-Diaz, C.; Gomez-Arboledas, A.; Moreno-Gonzalez, I. et al.
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela via Scopus - Elsevier

Human pluripotent stem cell-derived neural cells as a relevant platform for drug screening in alzheimer’s disease

International Journal of Molecular Sciences
2020 | Journal article
DOI: 10.3390/ijms21186867
EID:

2-s2.0-85091094795

Part of ISBN:

14220067 16616596
Contributors: Garcia-Leon, J.A.; Caceres-Palomo, L.; Sanchez-Mejias, E.; Mejias-Ortega, M.; Nuñez-Diaz, C.; Fernandez-Valenzuela, J.J.; Sanchez-Varo, R.; Davila, J.C.; Vitorica, J.; Gutierrez, A.
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela via Scopus - Elsevier

Distinct microglial responses in two transgenic murine models of TAU pathology

Frontiers in Cellular Neuroscience
2018 | Journal article
DOI: 10.3389/fncel.2018.00421
EID:

2-s2.0-85056881652

Part of ISBN:

16625102
Contributors: Romero-Molina, C.; Navarro, V.; Sanchez-Varo, R.; Jimenez, S.; Fernandez-Valenzuela, J.J.; Sanchez-Mico, M.V.; Muñoz-Castro, C.; Gutierrez, A.; Vitorica, J.; Vizuete, M.
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela via Scopus - Elsevier

Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease

GLIA
2018 | Journal article
DOI: 10.1002/glia.23270
EID:

2-s2.0-85040642435

Part of ISBN:

10981136 08941491
Contributors: Gomez-Arboledas, A.; Davila, J.C.; Sanchez-Mejias, E.; Navarro, V.; Nuñez-Diaz, C.; Sanchez-Varo, R.; Sanchez-Mico, M.V.; Trujillo-Estrada, L.; Fernandez-Valenzuela, J.J.; Vizuete, M. et al.
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela via Scopus - Elsevier

Descifrando la contribución patogénica de Abeta y TAU en modelos transgénicos de la enfermedad de Alzheimer

Actas Workshop Internacional Metabolic Reprogramming as a Target for Cancer and Other DIseases
2018-12-19 | Book chapter
Source: Self-asserted source
Juan Jose Fernandez-Valenzuela
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