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Effects of ACLY Inhibition on Body Weight Distribution: A Drug Target Mendelian Randomization Study

Genes
2024-08 | Journal article | Author
DOI: 10.3390/genes15081059
Contributors: Dipender Gill; Marie-Joe Dib; Rubinder Gill; Stefan R. Bornstein; Stephen Burgess; Andreas Birkenfeld
Source: check_circle
Multidisciplinary Digital Publishing Institute

Cerebrospinal and Brain Proteins Implicated in Neuropsychiatric and Risk Factor Traits: Evidence from Mendelian Randomization

Biomedicines
2024-01 | Journal article | Author
DOI: 10.3390/biomedicines12020327
Contributors: Roxane de La Harpe; Loukas Zagkos; Dipender Gill; Héléne T. Cronjé; Ville Karhunen
Source: check_circle
Multidisciplinary Digital Publishing Institute

Cerebrospinal Fluid C1-Esterase Inhibitor and Tie-1 Levels Affect Cognitive Performance: Evidence from Proteome-Wide Mendelian Randomization

Genes
2024-01 | Journal article | Author
DOI: 10.3390/genes15010071
Contributors: Loukas Zagkos; Marie-Joe Dib; Héléne T. Cronjé; Paul Elliott; Abbas Dehghan; Ioanna Tzoulaki; Dipender Gill; Iyas Daghlas
Source: check_circle
Multidisciplinary Digital Publishing Institute

Caffeine Intake, Plasma Caffeine Level, and Kidney Function: A Mendelian Randomization Study

Nutrients
2023-10 | Journal article | Author
DOI: 10.3390/nu15204422
Contributors: Alice Giontella; Roxane de La Harpe; Héléne T. Cronje; Loukas Zagkos; Benjamin Woolf; Susanna C. Larsson; Dipender Gill
Source: check_circle
Multidisciplinary Digital Publishing Institute

Associations of Genetically Predicted Vitamin B<sub>12</sub> Status across the Phenome

Nutrients
2022-11 | Journal article | Author
DOI: 10.3390/nu14235031
Contributors: Marie-Joe Dib; Kourosh R. Ahmadi; Loukas Zagkos; Dipender Gill; Brooke Morris; Paul Elliott; Abbas Dehghan; Ioanna Tzoulaki
Source: check_circle
Multidisciplinary Digital Publishing Institute

Unravelling the Distinct Effects of Systolic and Diastolic Blood Pressure Using Mendelian Randomisation

Genes
2022-07 | Journal article | Author
DOI: 10.3390/genes13071226
Contributors: Nhu Ngoc Le; Tran Q. B. Tran; Stefanie Lip; Linsay McCallum; John McClure; Anna F. Dominiczak; Dipender Gill; Sandosh Padmanabhan
Source: check_circle
Multidisciplinary Digital Publishing Institute

A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation.

Nature genetics
2022-06 | Journal article
DOI: 10.1038/s41588-022-01078-z
PMID: 35654975
Contributors: Vujkovic M; Ramdas S; Lorenz KM; Guo X; Darlay R; Cordell HJ; He J; Gindin Y; Chung C; Myers RP et al.
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Educational attainment as a modifier for the effect of polygenic scores for cardiovascular risk factors: cross-sectional and prospective analysis of UK Biobank.

International journal of epidemiology
2022-06 | Journal article
DOI: 10.1093/ije/dyac002
PMID: 35134953
PMC: PMC9189971
Contributors: Carter AR; Harrison S; Gill D; Davey Smith G; Taylor AE; Howe LD; Davies NM
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Genetically proxied IL-6 receptor inhibition and risk of polymyalgia rheumatica.

Annals of the rheumatic diseases
2022-06 | Journal article
DOI: 10.1136/annrheumdis-2022-222578
PMID: 35701152
Contributors: Zhao SS; Gill D
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Genome-wide meta-analysis of iron status biomarkers and the effect of iron on all-cause mortality in HUNT.

Communications biology
2022-06 | Journal article
DOI: 10.1038/s42003-022-03529-z
PMID: 35710628
PMC: PMC9203493
Contributors: Moksnes MR; Graham SE; Wu KH; Hansen AF; Gagliano Taliun SA; Zhou W; Thorstensen K; Fritsche LG; Gill D; Mason A et al.
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Sparse Dimensionality Reduction Approaches in Mendelian Randomization with highly correlated exposures

2022-06 | Preprint
DOI: 10.1101/2022.06.15.22276455
PPR: PPR508022
Contributors: Karageorgiou V; Gill D; Bowden J; Zuber V
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Systemic iron status and maternal pregnancy complications: a Mendelian randomization study.

International journal of epidemiology
2022-06 | Journal article
DOI: 10.1093/ije/dyac037
PMID: 35234877
Contributors: Rogne T; Burgess S; Gill D
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

The Potential of Genetic Data for Prioritizing Drug Repurposing Efforts.

Neurology
2022-06 | Journal article
DOI: 10.1212/wnl.0000000000200803
PMID: 35654591
Contributors: Gill D; Vujkovic M
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Transferability of genetic risk scores in African populations.

Nature medicine
2022-06 | Journal article
DOI: 10.1038/s41591-022-01835-x
PMID: 35654908
PMC: PMC9205766
Contributors: Kamiza AB; Toure SM; Vujkovic M; Machipisa T; Soremekun OS; Kintu C; Corpas M; Pirie F; Young E; Gill D et al.
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

TwoStepCisMR: A novel method and R package for attenuating bias in <i>cis</i>-MR

2022-06 | Preprint
DOI: 10.1101/2022.06.13.22276262
PPR: PPR507694
Contributors: Woolf B; Gill D
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Avoiding collider bias in Mendelian randomization when performing stratified analyses.

European journal of epidemiology
2022-05 | Journal article
DOI: 10.1007/s10654-022-00879-0
PMID: 35639294
Contributors: Coscia C; Gill D; Benítez R; Pérez T; Malats N; Burgess S
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Disentangling the effects of traits with shared clustered genetic predictors using multivariable Mendelian randomization.

Genetic epidemiology
2022-05 | Journal article
DOI: 10.1002/gepi.22462
PMID: 35638254
Contributors: Batool F; Patel A; Gill D; Burgess S
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Genetic evidence for vitamin D and cardiovascular disease: choice of variants is critical.

European heart journal
2022-05 | Journal article
DOI: 10.1093/eurheartj/ehab870
PMID: 34972215
Contributors: Burgess S; Gill D
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Genetically Predicted Pulse Pressure and Risk of Abdominal Aortic Aneurysm: A Mendelian Randomization Analysis.

Circulation. Genomic and precision medicine
2022-05 | Journal article
DOI: 10.1161/circgen.121.003575
PMID: 35522177
PMC: PMC9213080
Contributors: Burgess S; Chirinos JA; Damrauer SM; Gill D
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Multi-ancestry GWAS deciphers genetic architecture of abdominal aortic aneurysm and highlights <i>PCSK9</i> as a therapeutic target

2022-05 | Preprint
DOI: 10.1101/2022.05.27.22275607
PPR: PPR499366
Contributors: Roychowdhury T; Klarin D; Levin MG; Spin JM; Rhee YH; Deng A; Headley CA; Surakka I; Tsao NL; Gellatly C et al.
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

The Ca2+-gated channel TMEM16A amplifies capillary pericyte contraction and reduces cerebral blood flow after ischemia.

The Journal of clinical investigation
2022-05 | Journal article
DOI: 10.1172/jci154118
PMID: 35316222
PMC: PMC9057602
Contributors: Korte N; Ilkan Z; Pearson CL; Pfeiffer T; Singhal P; Rock JR; Sethi H; Gill D; Attwell D; Tammaro P
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Combining evidence from Mendelian randomization and colocalization: Review and comparison of approaches.

American journal of human genetics
2022-04 | Journal article
DOI: 10.1016/j.ajhg.2022.04.001
PMID: 35452592
PMC: PMC7612737
Contributors: Zuber V; Grinberg NF; Gill D; Manipur I; Slob EAW; Patel A; Wallace C; Burgess S
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Genetic risk and incident venous thromboembolism in middle-aged and older adults following Covid-19 vaccination

2022-04 | Preprint
DOI: 10.1101/2022.04.14.22273865
PPR: PPR484104
Contributors: Xie J; Prats-Uribe A; Maranon MG; Strauss VY; Gill D; Prieto-Alhambra D
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Genetically proxied PCSK9 inhibition provides indication of lower prostate cancer risk: a Mendelian randomization study

2022-04 | Preprint
DOI: 10.1101/2022.04.18.22274003
PPR: PPR483510
Contributors: Fang S; Yarmolinsky J; Gill D; Bull CJ; Perks CM; Smith GD; Gaunt TR; Richardson TG; the PRACTICAL consortium
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Lifestyle and metabolic factors for nonalcoholic fatty liver disease: Mendelian randomization study.

European journal of epidemiology
2022-04 | Journal article
DOI: 10.1007/s10654-022-00868-3
PMID: 35488966
Contributors: Yuan S; Chen J; Li X; Fan R; Arsenault B; Gill D; Giovannucci EL; Zheng JS; Larsson SC
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Plasma Caffeine Levels and Risk of Alzheimer&rsquo;s Disease and Parkinson&rsquo;s Disease: Mendelian Randomization Study

Nutrients
2022-04 | Journal article | Author
DOI: 10.3390/nu14091697
Contributors: Susanna C. Larsson; Benjamin Woolf; Dipender Gill
Source: check_circle
Multidisciplinary Digital Publishing Institute

Publisher Correction: Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus.

Nature communications
2022-04 | Journal article
DOI: 10.1038/s41467-022-29641-6
PMID: 35388009
PMC: PMC8986867
Contributors: Stacey D; Chen L; Stanczyk PJ; Howson JMM; Mason AM; Burgess S; MacDonald S; Langdown J; McKinney H; Downes K et al.
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus.

Nature communications
2022-03 | Journal article
DOI: 10.1038/s41467-022-28729-3
PMID: 35264566
PMC: PMC8907312
Contributors: Stacey D; Chen L; Stanczyk PJ; Howson JMM; Mason AM; Burgess S; MacDonald S; Langdown J; McKinney H; Downes K et al.
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Lipid traits and type 2 diabetes risk in African ancestry individuals: A Mendelian Randomization study.

EBioMedicine
2022-03 | Journal article
DOI: 10.1016/j.ebiom.2022.103953
PMID: 35325778
PMC: PMC8941323
Contributors: Soremekun O; Karhunen V; He Y; Rajasundaram S; Liu B; Gkatzionis A; Soremekun C; Udosen B; Musa H; Silva S et al.
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Polygenic Prediction of Type 2 Diabetes in Africa.

Diabetes care
2022-03 | Journal article
DOI: 10.2337/dc21-0365
PMID: 35015074
PMC: PMC8918234
Contributors: Chikowore T; Ekoru K; Vujkovi M; Gill D; Pirie F; Young E; Sandhu MS; McCarthy M; Rotimi C; Adeyemo A et al.
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Venous Thromboembolism in Ambulatory Covid-19 patients: Clinical and Genetic Determinants

2022-03 | Preprint
DOI: 10.1101/2022.03.22.22272748
PPR: PPR471670
Contributors: Xie J; Prats-Uribe A; Feng Q; Wang Y; Gill D; Paredes R; PRIETO-ALHAMBRA D
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

ADAMTS5 as a therapeutic target for osteoarthritis: Mendelian randomisation study.

Annals of the rheumatic diseases
2022-02 | Journal article
DOI: 10.1136/annrheumdis-2021-222007
PMID: 35131763
Contributors: Zhao SS; Karhunen V; Morris AP; Gill D
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Corrigendum to: Genetic evidence for vitamin D and cardiovascular disease: choice of variants is critical.

European heart journal
2022-02 | Journal article
DOI: 10.1093/eurheartj/ehac070
PMID: 35146516
Contributors: Burgess S; Gill D
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Genetically Predicted Neutrophil-to-Lymphocyte Ratio and Coronary Artery Disease: Evidence From Mendelian Randomization.

Circulation. Genomic and precision medicine
2022-02 | Journal article
DOI: 10.1161/circgen.121.003553
PMID: 35103484
PMC: PMC7612391
Contributors: Cupido AJ; Kraaijenhof JM; Burgess S; Asselbergs FW; Hovingh GK; Gill D
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Genetically predicted sex hormone levels and health outcomes: phenome-wide Mendelian randomization investigation.

International journal of epidemiology
2022-02 | Journal article
DOI: 10.1093/ije/dyac036
PMID: 35218343
Contributors: Yuan S; Wang L; Sun J; Yu L; Zhou X; Yang J; Zhu Y; Gill D; Burgess S; Denny JC et al.
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Systematic review of Mendelian randomization studies on risk of cancer.

BMC medicine
2022-02 | Journal article
DOI: 10.1186/s12916-022-02246-y
PMID: 35105367
PMC: PMC8809022
Contributors: Markozannes G; Kanellopoulou A; Dimopoulou O; Kosmidis D; Zhang X; Wang L; Theodoratou E; Gill D; Burgess S; Tsilidis KK
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

The Ca<sup>2+</sup>-gated Cl<sup>-</sup> channel TMEM16A amplifies capillary pericyte contraction reducing cerebral blood flow after ischemia

2022-02 | Preprint
DOI: 10.1101/2022.02.03.479031
PPR: PPR450836
Contributors: Korte N; Ilkan Z; Pearson C; Pfeiffer T; Singhal P; Rock J; Sethi H; Gill D; Attwell D; Tammaro P
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

The evolution of mendelian randomization for investigating drug effects.

PLoS medicine
2022-02 | Journal article
DOI: 10.1371/journal.pmed.1003898
PMID: 35113864
PMC: PMC8812877
Contributors: Gill D; Burgess S
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Circulating inflammatory cytokines and risk of five cancers: a Mendelian randomization analysis.

BMC medicine
2022-01 | Journal article
DOI: 10.1186/s12916-021-02193-0
PMID: 35012533
PMC: PMC8750876
Contributors: Bouras E; Karhunen V; Gill D; Huang J; Haycock PC; Gunter MJ; Johansson M; Brennan P; Key T; Lewis SJ et al.
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Maternal Hypertension Increases Risk of Preeclampsia and Low Fetal Birthweight: Genetic Evidence From a Mendelian Randomization Study.

Hypertension (Dallas, Tex. : 1979)
2022-01 | Journal article
DOI: 10.1161/hypertensionaha.121.18617
PMID: 35138876
PMC: PMC7612410
Contributors: Ardissino M; Slob EAW; Millar O; Reddy RK; Lazzari L; Patel KHK; Ryan D; Johnson MR; Gill D; Ng FS
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Morning Cortisol and Circulating Inflammatory Cytokine Levels: A Mendelian Randomisation Study

Genes
2022-01 | Journal article | Author
DOI: 10.3390/genes13010116
Contributors: Skanda Rajasundaram; Rezbieara Rahman; Benjamin Woolf; Sizheng Steven Zhao; Dipender Gill
Source: check_circle
Multidisciplinary Digital Publishing Institute

Noise-augmented directional clustering of genetic association data identifies distinct mechanisms underlying obesity.

PLoS genetics
2022-01 | Journal article
DOI: 10.1371/journal.pgen.1009975
PMID: 35085229
PMC: PMC8794082
Contributors: Grant AJ; Gill D; Kirk PDW; Burgess S
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Obesity Partially Mediates the Diabetogenic Effect of Lowering LDL Cholesterol.

Diabetes care
2022-01 | Journal article
DOI: 10.2337/dc21-1284
PMID: 34789503
Contributors: Wu P; Moon JY; Daghlas I; Franco G; Porneala BC; Ahmadizar F; Richardson TG; Isaksen JL; Hindy G; Yao J et al.
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Sleep Disordered Breathing, Obesity and Atrial Fibrillation: A Mendelian Randomisation Study

Genes
2022-01 | Journal article | Author
DOI: 10.3390/genes13010104
Contributors: Maddalena Ardissino; Rohin Reddy; Eric A. W. Slob; Kiran H. K. Patel; David K. Ryan; Dipender Gill; Fu Siong Ng
Source: check_circle
Multidisciplinary Digital Publishing Institute

Association of Thyroid Function with Blood Pressure and Cardiovascular Disease: A Mendelian Randomization

Journal of Personalized Medicine
2021-12 | Journal article | Author
DOI: 10.3390/jpm11121306
Contributors: Alice Giontella; Luca A. Lotta; John D. Overton; Aris Baras; on behalf of Regeneron Genetics Center; Andrea Sartorio; Pietro Minuz; Dipender Gill; Olle Melander; Cristiano FAVA
Source: check_circle
Multidisciplinary Digital Publishing Institute

Distinguishing causation from genetic correlation in a Mendelian randomisation framework.

The European respiratory journal
2021-12 | Journal article
DOI: 10.1183/13993003.01346-2021
PMID: 34887314
Contributors: Gill D; Burgess S
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

A case series of vaccine-induced thrombotic thrombocytopenia in a London teaching hospital.

British journal of clinical pharmacology
2021-11 | Journal article
DOI: 10.1111/bcp.15116
PMID: 34694650
PMC: PMC8652623
Contributors: Watts I; Smith D; Mounter S; Baker EH; Hitchings AW; Gill D
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Cardiovascular Risk Factors and MRI Markers of Cerebral Small Vessel Disease: A Mendelian Randomization Study.

Neurology
2021-11 | Journal article
DOI: 10.1212/wnl.0000000000013120
PMID: 34845052
Contributors: Taylor-Bateman V; Gill D; Georgakis M; Malik R; Munroe P; Traylor M; International Consortium of Blood Pressure (ICBP)
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Leveraging Genetic Data to Elucidate the Relationship Between COVID-19 and Ischemic Stroke.

Journal of the American Heart Association
2021-11 | Journal article
DOI: 10.1161/jaha.121.022433
PMID: 34755518
PMC: PMC8751930
Contributors: Zuber V; Cameron A; Myserlis EP; Bottolo L; Fernandez-Cadenas I; Burgess S; Anderson CD; Dawson J; Gill D
Source: Self-asserted source
Dipender Gill via Europe PubMed Central

Modifiable Risk Factors for Intracranial Aneurysm and Aneurysmal Subarachnoid Hemorrhage: A Mendelian Randomization Study.

Journal of the American Heart Association
2021-11 | Journal article
DOI: 10.1161/jaha.121.022277
PMID: 34729997
PMC: PMC8751955
Contributors: Karhunen V; Bakker MK; Ruigrok YM; Gill D; Larsson SC
Source: Self-asserted source
Dipender Gill via Europe PubMed Central
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Peer review (28 reviews for 16 publications/grants)

Review activity for BMC medicine (3)
Review activity for BMJ medicine. (1)
Review activity for Communications biology. (1)
Review activity for International journal of obesity. (1)
Review activity for Journal of cancer research and clinical oncology. (1)
Review activity for Journal of epidemiology and community health (1)
Review activity for Molecular brain (1)
Review activity for Molecular neurobiology. (1)
Review activity for Molecular psychiatry. (1)
Review activity for Nature cardiovascular research. (1)
Review activity for Nature communications (1)
Review activity for Nature medicine. (2)
Review activity for PLoS biology. (1)
Review activity for PLOS genetics. (2)
Review activity for PLoS medicine. (5)
Review activity for The journal of clinical endocrinology and metabolism. (5)
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