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Keywords

venom-drug discovery, melanoma, senolytics, cancer

Countries

Spain, Australia

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Employment (5)

IMDEA Food: Madrid, ES

2019-02-10 to present | TALENTO Fellow (Precision Nutrition & Aging)
Employment
Source: Self-asserted source
Maria Ikonomopoulou

Imdea Food Institute: Madrid, ES

2017-09-01 to 2018-09-01 | "MARIE CURIE" AMAROUT Fellow (Nutrition and Ageing)
Employment
Source: Self-asserted source
Maria Ikonomopoulou

QIMR Berghofer Medical Research Institute: Herston, QLD, AU

2014-09-24 to 2017-08-10 | Research Officer
Employment
Source: Self-asserted source
Maria Ikonomopoulou

The University of Queensland: Brisbane, Queensland, AU

2010-01-11 to 2014-06-30 | Research Officer (The Institute for Molecular Bioscience)
Employment
Source: Self-asserted source
Maria Ikonomopoulou

QIMR Berghofer Medical Research Institute: Herston, QLD, AU

2010-03-08 to 2010-12-31 | Research Officer
Employment
Source: Self-asserted source
Maria Ikonomopoulou

Education and qualifications (3)

The University of Queensland: Brisbane, Queensland, AU

2004 to 2009 | PhD (Biomedical Sciences)
Education
Source: Self-asserted source
Maria Ikonomopoulou

University of Tasmania: Hobart, TAS, AU

2001 to 2003 | MSc (Zoology)
Education
Source: Self-asserted source
Maria Ikonomopoulou

Technical Educational Institute of Western Macedonia: Florina, GR

1996-09 to 2000-09 | BSc (Animal Production)
Education
Source: Self-asserted source
Maria Ikonomopoulou

Works (40)

The heavy subunit of ferritin stimulates NLRP3 inflammasomes in hepatic stellate cells through ICAM-1 to drive hepatic inflammation

Science Signaling
2024-04-02 | Journal article
DOI: 10.1126/scisignal.ade4335
Contributors: Manuel A. Fernandez-Rojo; Michael A. Pearen; Anita G. Burgess; Maria P. Ikonomopoulou; Diem Hoang-Le; Berit Genz; Silvia L. Saggiomo; Sujeevi S. K. Nawaratna; Maura Poli; Regina Reissmann et al.
Source: check_circle
Crossref

Web of venom: exploration of big data resources in animal toxin research

GigaScience
2024-01-02 | Journal article
DOI: 10.1093/gigascience/giae054
Contributors: Giulia Zancolli; Björn Marcus von Reumont; Gregor Anderluh; Figen Caliskan; Maria Luisa Chiusano; Jacob Fröhlich; Evroula Hapeshi; Benjamin-Florian Hempel; Maria P Ikonomopoulou; Florence Jungo et al.
Source: check_circle
Crossref

Malaysian and Chinese King Cobra Venom Cytotoxicity in Melanoma and Neonatal Foreskin Fibroblasts Is Mediated by Age and Geography

Toxins
2023-09-04 | Journal article
DOI: 10.3390/toxins15090549
Contributors: Bianca Op den Brouw; Manuel A. Fernandez-Rojo; Tom Charlton; Bryan G. Fry; Maria P. Ikonomopoulou
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Functional and Proteomic Insights into Aculeata Venoms

Toxins
2023-03-16 | Journal article
DOI: 10.3390/toxins15030224
Contributors: Daniel Dashevsky; Kate Baumann; Eivind A. B. Undheim; Amanda Nouwens; Maria P. Ikonomopoulou; Justin O. Schmidt; Lilin Ge; Hang Fai Kwok; Juanita Rodriguez; Bryan G. Fry
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

The structural conformation of the tachykinin domain drives the anti-tumoural activity of an octopus peptide in melanoma BRAFV600E

British Journal of Pharmacology
2022-07-12 | Journal article
DOI: 10.1111/bph.15923
Part of ISSN: 0007-1188
Part of ISSN: 1476-5381
Source: Self-asserted source
Maria Ikonomopoulou

Modern venomics—Current insights, novel methods, and future perspectives in biological and applied animal venom research

GigaScience
2022-05-18 | Journal article
Source: Self-asserted source
Maria Ikonomopoulou

Pharmacological Characterisation of Pseudocerastes and Eristicophis Viper Venoms Reveal Anticancer (Melanoma) Properties and a Potentially Novel Mode of Fibrinogenolysis

International Journal of Molecular Sciences
2021-06-27 | Journal article
DOI: 10.3390/ijms22136896
Contributors: Bianca op den Brouw; Parviz Ghezellou; Nicholas R. Casewell; Syed Abid Ali; Behzad Fathinia; Bryan G. Fry; Mettine H.A. Bos; Maria P. Ikonomopoulou
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Immunological Responses to Envenomation.

Frontiers in immunology
2021-05-10 | Journal article
DOI: 10.3389/fimmu.2021.661082
PMID: 34040609
PMC: PMC8141633
Contributors: Maria Ikonomopoulou
Source: Self-asserted source
Maria Ikonomopoulou

LXR stimulates a metabolic switch and reveals cholesterol homeostasis as a statin target in Tasmanian devil facial tumor disease.

Cell reports
2021-03-01 | Journal article
DOI: 10.1016/j.celrep.2021.108851
PMID: 33730574
Source: Self-asserted source
Maria Ikonomopoulou

ERK and mTORC1 Inhibitors Enhance the Anti-Cancer Capacity of the Octpep-1 Venom-Derived Peptide in Melanoma BRAF(V600E) Mutations

Toxins
2021-02 | Journal article | Author
DOI: 10.3390/toxins13020146
Contributors: Moral-Sanz, J; Manuel A. Fernandez-Rojo; Jeremy Potriquet; Pamela Mukhopadhyay; Andreas Brust; Patrick Wilhelm; Taylor Smallwood; Richard Clark; Bryan Fry; Paul F. Alewood et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

Extensive Variation in the Activities of Pseudocerastes and Eristicophis Viper Venoms Suggests Divergent Envenoming Strategies Are Used for Prey Capture

Toxins
2021-02-02 | Journal article
DOI: 10.3390/toxins13020112
Contributors: Bianca op den Brouw; Francisco C. P. Coimbra; Lachlan A. Bourke; Tam Minh Huynh; Danielle H. W. Vlecken; Parviz Ghezellou; Jeroen C. Visser; James S. Dobson; Manuel A. Fernandez-Rojo; Maria P. Ikonomopoulou et al.
Source: check_circle
Crossref

Food Implications in Central Sensitization Syndromes

Journal of Clinical Medicine
2020-12-19 | Journal article
DOI: 10.3390/jcm9124106
Contributors: Elena Aguilar-Aguilar; Helena Marcos-Pasero; Maria P. Ikonomopoulou; Viviana Loria-Kohen
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Venom of the Red-Bellied Black Snake Pseudechis porphyriacus Shows Immunosuppressive Potential.

Toxins
2020-10-26 | Journal article
DOI: 10.3390/toxins12110674
PMID: 33114591
PMC: PMC7693913
Contributors: Maria Ikonomopoulou
Source: Self-asserted source
Maria Ikonomopoulou

Large expert-curated database for benchmarking document similarity detection in biomedical literature search

Database
2019 | Journal article
DOI: 10.1093/database/baz085
Part of ISSN: 1758-0463
Source: Self-asserted source
Maria Ikonomopoulou

Identification and characterization of Cardiac Glycosides as senolytic compounds

Nature Communications
2019-12 | Journal article
DOI: 10.1038/s41467-019-12888-x
Part of ISSN: 2041-1723
Source: Self-asserted source
Maria Ikonomopoulou

Immune drug discovery from venoms

Toxicon
2018 | Journal article
DOI: 10.1016/j.toxicon.2017.11.006
EID:

2-s2.0-85034845556
Contributors: Jimenez, R.; Ikonomopoulou, M.P.; Lopez, J.A.; Miles, J.J.
Source: Self-asserted source
Maria Ikonomopoulou via Scopus - Elsevier

Proteomic and functional variation within black snake venoms (Elapidae: Pseudechis)

Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology
2018 | Journal article
DOI: 10.1016/j.cbpc.2018.01.001
EID:

2-s2.0-85041502710
Contributors: Goldenberg, J.; Cipriani, V.; Jackson, T.N.W.; Arbuckle, K.; Debono, J.; Dashevsky, D.; Panagides, N.; Ikonomopoulou, M.P.; Koludarov, I.; Li, B. et al.
Source: Self-asserted source
Maria Ikonomopoulou via Scopus - Elsevier

Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells.

Cell Death Discovery
2018-12 | Journal article
DOI: 10.1038/s41420-018-0030-0
PMID: 29531816
PMC: PMC5841354
Contributors: Fernandez-Rojo MA; Deplazes E; Pineda SS; Brust A; Marth T; Wilhelm P; Martel N; Ramm GA; Mancera RL; Alewood PF et al.
Source: Self-asserted source
Maria Ikonomopoulou via Europe PubMed Central

Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation.

Scientific reports
2018-08 | Journal article
DOI: 10.1038/s41598-018-29826-4
PMID: 30068931
Contributors: Ikonomopoulou MP; Fernandez-Rojo MA; Pineda SS; Cabezas-Sainz P; Winnen B; Morales RAV; Brust A; Sánchez L; Alewood PF; Ramm GA et al.
Source: Self-asserted source
Maria Ikonomopoulou via Europe PubMed Central

The antiproliferative and apoptotic profile of gomesin against DFTD

Cell Death & Disease
2018-08-06 | Journal article
DOI: 10.1038/s41419-018-0885-2
Contributors: Maria P. Ikonomopoulou; Manuel A. Fernandez-Rojo
Source: check_circle
Crossref

How the cobra got its flesh-eating venom: Cytotoxicity as a defensive innovation and its co-evolution with hooding, aposematic marking, and spitting

Toxins
2017 | Journal article
DOI: 10.3390/toxins9030103
EID:

2-s2.0-85015392737
Contributors: Panagides, N.; Jackson, T.N.W.; Ikonomopoulou, M.P.; Arbuckle, K.; Pretzler, R.; Yang, D.C.; Ali, S.A.; Koludarov, I.; Dobson, J.; Sanker, B. et al.
Source: Self-asserted source
Maria Ikonomopoulou via Scopus - Elsevier

Insect-active toxins with promiscuous pharmacology from the African theraphosid spider Monocentropus balfouri

Toxins
2017 | Journal article
DOI: 10.3390/toxins9050155
EID:

2-s2.0-85019019312
Contributors: Smith, J.J.; Herzig, V.; Ikonomopoulou, M.P.; Dziemborowicz, S.; Bosmans, F.; Nicholson, G.M.; King, G.F.
Source: Self-asserted source
Maria Ikonomopoulou via Scopus - Elsevier

Isolation of two insecticidal toxins from venom of the Australian theraphosid spider Coremiocnemis tropix

Toxicon
2016 | Journal article
DOI: 10.1016/j.toxicon.2016.10.013
EID:

2-s2.0-84994571093
Contributors: Ikonomopoulou, M.P.; Smith, J.J.; Herzig, V.; Pineda, S.S.; Dziemborowicz, S.; Er, S.-Y.; Durek, T.; Gilchrist, J.; Alewood, P.F.; Nicholson, G.M. et al.
Source: Self-asserted source
Maria Ikonomopoulou via Scopus - Elsevier

Molecular basis of the remarkable species selectivity of an insecticidal sodium channel toxin from the African spider Augacephalus ezendami

Scientific Reports
2016 | Journal article
DOI: 10.1038/srep29538
EID:

2-s2.0-84977604242
Contributors: Herzig, V.; Ikonomopoulou, M.; Smith, J.J.; Dziemborowicz, S.; Gilchrist, J.; Kuhn-Nentwig, L.; Rezende, F.O.; Moreira, L.A.; Nicholson, G.M.; Bosmans, F. et al.
Source: Self-asserted source
Maria Ikonomopoulou via Scopus - Elsevier

Therapeutic applications of spider-venom peptides

RSC Drug Discovery Series
2015 | Book
EID:

2-s2.0-84937427186
Contributors: Smith, J.J.; Lau, C.H.Y.; Herzig, V.; Ikonomopoulou, M.P.; Rash, L.D.; King, G.F.
Source: Self-asserted source
Maria Ikonomopoulou via Scopus - Elsevier

Spider venomics: Implications for drug discovery

Future Medicinal Chemistry
2014 | Journal article
DOI: 10.4155/FMC.14.103
EID:

2-s2.0-84911922472
Contributors: Pineda, S.S.; Undheim, E.A.B.; Rupasinghe, D.B.; Ikonomopoulou, M.P.; King, G.F.
Source: Self-asserted source
Maria Ikonomopoulou via Scopus - Elsevier

Accumulation of trace metals in the embryos and hatchlings of Chelonia mydas from Peninsular Malaysia incubated at different temperatures

Science of the Total Environment
2013 | Journal article
DOI: 10.1016/j.scitotenv.2013.02.031
EID:

2-s2.0-84875236973
Contributors: Ikonomopoulou, M.P.; Olszowy, H.; Francis, R.; Ibrahim, K.; Whittier, J.
Source: Self-asserted source
Maria Ikonomopoulou via Scopus - Elsevier

Caveolin-1 is necessary for hepatic oxidative lipid metabolism: Evidence for crosstalk between caveolin-1 and bile acid signaling

Cell Reports
2013 | Journal article
DOI: 10.1016/j.celrep.2013.06.017
EID:

2-s2.0-84880848107
Contributors: Fernández-Rojo, M.; Gongora, M.; Fitzsimmons, R.L.; Martel, N.; Martin, S.D.; Nixon, S.J.; Brooks, A.J.; Ikonomopoulou, M.P.; Martin, S.; Lo, H.P. et al.
Source: Self-asserted source
Maria Ikonomopoulou via Scopus - Elsevier

Natural born insect killers: Spider-venom peptides and their potential for managing arthropod pests

Outlooks on Pest Management
2013 | Journal article
DOI: 10.1564/v24_feb_05
EID:

2-s2.0-84874409702
Contributors: Ikonomopoulou, M.; King, G.
Source: Self-asserted source
Maria Ikonomopoulou via Scopus - Elsevier

An investigation of organochlorine and polychlorobiphenyl concentrations in the blood and eggs of the carnivorous flatback turtle, Natator depressus, from Queensland, Australia

Chelonian Conservation and Biology
2012 | Journal article
DOI: 10.2744/CCB-0981.1
EID:

2-s2.0-84872691735
Contributors: Ikonomopoulou, M.P.; Hodge, M.; Whittier, J.M.
Source: Self-asserted source
Maria Ikonomopoulou via Scopus - Elsevier

Quantitative sex identification of hatchling green sea turtles (chelonia mydas)

Journal of Herpetology
2012 | Journal article
DOI: 10.1670/10-333
EID:

2-s2.0-84867059245
Contributors: Ikonomopoulou, M.P.; Aland, R.C.; Ibrahim, K.; Gosden, E.; Whittier, J.M.
Source: Self-asserted source
Maria Ikonomopoulou via Scopus - Elsevier

Trace element concentrations in nesting flatback turtles (Natator depressus) from Curtis Island, Queensland, Australia

Marine Environmental Research
2011 | Journal article
DOI: 10.1016/j.marenvres.2010.09.003
EID:

2-s2.0-78651087934
Contributors: Ikonomopoulou, M.P.; Olszowy, H.; Limpus, C.; Francis, R.; Whittier, J.
Source: Self-asserted source
Maria Ikonomopoulou via Scopus - Elsevier

35 gene-environment interactions in crohn's disease: identification of a novel SNP that interacts strongly with smoking to shorten time to first resection

Gastroenterology
2010 | Conference paper
DOI: DOI: 10.1016/S0016-5085(10)60029-7
Source: Self-asserted source
Maria Ikonomopoulou

The effect of organochlorines and heavy metals on sex steroid-binding proteins in vitro in the plasma of nesting green turtles, Chelonia mydas

Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology
2009 | Journal article
DOI: 10.1007/s00360-009-0347-3
EID:

2-s2.0-67849113912
Contributors: Ikonomopoulou, M.P.; Olszowy, H.; Hodge, M.; Bradley, A.J.
Source: Self-asserted source
Maria Ikonomopoulou via Scopus - Elsevier

Sex steroid binding proteins in the plasma of hatchling Chelonia mydas

Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology
2008 | Journal article
DOI: 10.1007/s00360-008-0271-y
EID:

2-s2.0-49349098207
Contributors: Ikonomopoulou, M.P.; Ibrahim, K.; Bradley, A.J.
Source: Self-asserted source
Maria Ikonomopoulou via Scopus - Elsevier

Identification and properties of steroid-binding proteins in nesting Chelonia mydas plasma

Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology
2006 | Journal article
DOI: 10.1007/s00360-006-0099-2
EID:

2-s2.0-33750090049
Contributors: Ikonomopoulou, M.P.; Bradley, A.J.; Whittier, J.M.; Ibrahim, K.
Source: Self-asserted source
Maria Ikonomopoulou via Scopus - Elsevier

The development of endothermy during pouch life in the eastern barred bandicoot (Perameles gunnii), a marsupial

Physiological and Biochemical Zoology
2006 | Journal article
DOI: 10.1086/502819
EID:

2-s2.0-33744942892
Contributors: Ikonomopoulou, M.P.; Rose, R.W.
Source: Self-asserted source
Maria Ikonomopoulou via Scopus - Elsevier

Changes in milk composition during lactation in the eastern barred bandicoot (Perameles gunnii) (Marsupialia: Peramelidae)

Australian Journal of Zoology
2005 | Journal article
DOI: 10.1071/ZO04044
EID:

2-s2.0-17444373514
Contributors: Ikonomopoulou, M.P.; Smolenski, A.P.; Rose, R.W.
Source: Self-asserted source
Maria Ikonomopoulou via Scopus - Elsevier

Shivering and non-shivering thermogenesis in a marsupial, the eastern barred bandicoot (Perameles gunnii)

Journal of Thermal Biology
2005 | Journal article
DOI: 10.1016/j.jtherbio.2004.07.006
EID:

2-s2.0-13844276678
Contributors: Rose, R.W.; Ikonomopoulou, M.P.
Source: Self-asserted source
Maria Ikonomopoulou via Scopus - Elsevier

The metabolic rate and thermal conductance of the eastern barred bandicoot (Perameles gunnii) at different ambient temperatures

Australian Journal of Zoology
2003 | Journal article
DOI: 10.1071/ZO03064
EID:

2-s2.0-1542789993
Contributors: Ikonomopoulou, M.P.; Rose, R.W.
Source: Self-asserted source
Maria Ikonomopoulou via Scopus - Elsevier

Peer review (8 reviews for 5 publications/grants)

Review activity for Current oncology. (1)
Review activity for International journal of biological macromolecules. (3)
Review activity for Metabolites. (2)
Review activity for Science. (1)
Review activity for Toxicon. (1)
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