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Works (38)

Geometrically constrained cytoskeletal reorganisation modulates DNA nanostructures uptake

Journal of Materials Chemistry B
2025 | Journal article
DOI: 10.1039/D5TB00074B
Contributors: Petra Elblová; Hana Andělová; Mariia Lunova; Judita Anthi; Skylar J.W. Henry; Xinyi Tu; Alexandr Dejneka; Milan Jirsa; Nicholas Stephanopoulos; Oleg Lunov
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Crossref

Peptide-coated DNA nanostructures as a platform for control of lysosomal function in cells

Chemical Engineering Journal
2024-10 | Journal article
DOI: 10.1016/j.cej.2024.155633
Contributors: Petra Elblová; Mariia Lunova; Skylar J.W. Henry; Xinyi Tu; Alicia Calé; Alexandr Dejneka; Jarmila Havelková; Yuriy Petrenko; Milan Jirsa; Nicholas Stephanopoulos et al.
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Click-Chemistry-Enabled Functionalization of Cellulose Nanocrystals with Single-Stranded DNA for Directed Assembly

ACS Biomaterials Science & Engineering
2024-10-14 | Journal article
DOI: 10.1021/acsbiomaterials.4c01518
Contributors: Daria Bukharina; Katherine Cauffiel; Laura Mae Killingsworth; Justin A. Brackenridge; Valeriia Poliukhova; Minkyu Kim; Justin Brower; Julio Bernal-Chanchavac; Nicholas Stephanopoulos; Vladimir V. Tsukruk
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Templating Peptide Chemistry with Nucleic Acids: Toward Artificial Ribosomes, Cell-Specific Therapeutics, and Novel Protein-Mimetic Architectures

Biomacromolecules
2024-07-08 | Journal article
DOI: 10.1021/acs.biomac.4c00372
Contributors: Alexandra Novacek; Bryan Ugaz; Nicholas Stephanopoulos
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Construction of Reconfigurable and Polymorphic DNA Origami Assemblies with Coiled‐Coil Patches and Patterns

Advanced Science
2024-05 | Journal article
DOI: 10.1002/advs.202307257
Contributors: Teng Teng; Julio Bernal‐Chanchavac; Nicholas Stephanopoulos; Carlos E. Castro
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Inverse design of a pyrochlore lattice of DNA origami through model-driven experiments

Science
2024-05-17 | Journal article
DOI: 10.1126/science.adl5549
Contributors: Hao Liu; Michael Matthies; John Russo; Lorenzo Rovigatti; Raghu Pradeep Narayanan; Thong Diep; Daniel McKeen; Oleg Gang; Nicholas Stephanopoulos; Francesco Sciortino et al.
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DNA-Nanostructure-Guided Assembly of Proteins into Programmable Shapes

Nano Letters
2024-02-07 | Journal article
DOI: 10.1021/acs.nanolett.3c04497
Contributors: Qinyi Lu; Yang Xu; Erik Poppleton; Kun Zhou; Petr Sulc; Nicholas Stephanopoulos; Yonggang Ke
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Calcium-triggered DNA-mediated membrane fusion in synthetic cells

Chemical Communications
2023 | Journal article
DOI: 10.1039/D3CC02204H
Contributors: Yen-Yu Hsu; Samuel J. Chen; Julio Bernal-Chanchavac; Bineet Sharma; Hossein Moghimianavval; Nicholas Stephanopoulos; Allen P. Liu
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CytoDirect: A Nucleic Acid Nanodevice for Specific and Efficient Delivery of Functional Payloads to the Cytoplasm

Journal of the American Chemical Society
2023-12-20 | Journal article
DOI: 10.1021/jacs.3c07491
Contributors: Lu Yu; Yang Xu; Md Al-Amin; Shuoxing Jiang; Matthew Sample; Abhay Prasad; Nicholas Stephanopoulos; Petr Šulc; Hao Yan
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Site-Specific Arrangement and Structure Determination of Minor Groove Binding Molecules in Self-Assembled Three-Dimensional DNA Crystals

Journal of the American Chemical Society
2023-12-06 | Journal article
DOI: 10.1021/jacs.3c07802
Contributors: Chad R. Simmons; Alex Buchberger; Skylar J.W. Henry; Alexandra Novacek; Nour Eddine Fahmi; Tara MacCulloch; Nicholas Stephanopoulos; Hao Yan
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Construction and reconfiguration of dynamic DNA origami assemblies with coiled-coil patches and patterns

2023-09-24 | Preprint
DOI: 10.1101/2023.09.23.559112
Contributors: T. Teng; J. Bernal-Chanchavac; N. Stephanopoulos; C.E. Castro
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Self‐Assembly of Hybrid Peptide−DNA Nanostructures using Homotrimeric Coiled‐Coil/Nucleic Acid Building Blocks

ChemBioChem
2023-06-13 | Journal article
DOI: 10.1002/cbic.202300423
Contributors: Alex Buchberger; Md Al‐Amin; Chad R. Simmons; Nicholas Stephanopoulos
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Atomistic Picture of Opening–Closing Dynamics of DNA Holliday Junction Obtained by Molecular Simulations

Journal of Chemical Information and Modeling
2023-05-08 | Journal article
DOI: 10.1021/acs.jcim.3c00358
Contributors: Zhengyue Zhang; Jiří Šponer; Giovanni Bussi; Vojtěch Mlýnský; Petr Šulc; Chad R. Simmons; Nicholas Stephanopoulos; Miroslav Krepl
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Crossref

Proximity-enhanced synthesis of DNA–peptide–DNA triblock molecules

Chemical Communications
2022 | Journal article
DOI: 10.1039/D1CC04970D
Contributors: Tara MacCulloch; Alexandra Novacek; Nicholas Stephanopoulos
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Bioactive Fibronectin-III10–DNA Origami Nanofibers Promote Cell Adhesion and Spreading

ACS Applied Bio Materials
2022-10-17 | Journal article
DOI: 10.1021/acsabm.2c00303
Contributors: Alex Buchberger; Kyle Riker; Julio Bernal-Chanchavac; Raghu Pradeep Narayanan; Chad R. Simmons; Nour Eddine Fahmi; Ronit Freeman; Nicholas Stephanopoulos
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The interactions between DNA nanostructures and cells: A critical overview from a cell biology perspective

Acta Biomaterialia
2022-07 | Journal article
DOI: 10.1016/j.actbio.2022.04.046
Contributors: Adam Frtús; Barbora Smolková; Mariia Uzhytchak; Mariia Lunova; Milan Jirsa; Skylar J.W. Henry; Alexandr Dejneka; Nicholas Stephanopoulos; Oleg Lunov
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Uncovering temporospatial sensitive TBI targeting strategies via in vivo phage display

Science Advances
2022-07-22 | Journal article
DOI: 10.1126/sciadv.abo5047
Contributors: Briana I. Martinez; Gergey Alzaem Mousa; Kiera Fleck; Tara MacCulloch; Chris W. Diehnelt; Nicholas Stephanopoulos; Sarah E. Stabenfeldt
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The influence of Holliday junction sequence and dynamics on DNA crystal self-assembly

Nature Communications
2022-06-03 | Journal article
DOI: 10.1038/s41467-022-30779-6
Contributors: Chad R. Simmons; Tara MacCulloch; Miroslav Krepl; Michael Matthies; Alex Buchberger; Ilyssa Crawford; Jiří Šponer; Petr Šulc; Nicholas Stephanopoulos; Hao Yan
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Nanoscale Structures and Materials from the Self-assembly of Polypeptides and DNA

Current Topics in Medicinal Chemistry
2022-03 | Journal article
DOI: 10.2174/1568026621666211215142916
Contributors: Julio Bernal-Chanchavac; Md. Al-Amin; Nicholas Stephanopoulos
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Programmable, self-assembled DNA nanodevices for cellular programming and tissue engineering

Nanoscale
2021 | Journal article
DOI: 10.1039/D1NR04475C
Contributors: Ankit Gangrade; Nicholas Stephanopoulos; Dhiraj Bhatia
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Functionalizing DNA nanostructures for therapeutic applications

WIREs Nanomedicine and Nanobiotechnology
2021-11 | Journal article
DOI: 10.1002/wnan.1729
Contributors: Skylar J. W. Henry; Nicholas Stephanopoulos
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Reversible Control of Gelatin Hydrogel Stiffness by Using DNA Crosslinkers**

ChemBioChem
2021-05-14 | Journal article
DOI: 10.1002/cbic.202100030
Contributors: Alex Buchberger; Harpinder Saini; Kiarash Rahmani Eliato; Azadeh Zare; Ryan Merkley; Yang Xu; Julio Bernal; Robert Ros; Mehdi Nikkhah; Nicholas Stephanopoulos
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DNA Nanodevices as Mechanical Probes of Protein Structure and Function

Applied Sciences
2021-03-21 | Journal article
DOI: 10.3390/app11062802
Contributors: Nicholas Stephanopoulos; Petr Šulc
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Preferred source (of 2)‎

A Self‐Assembled Rhombohedral DNA Crystal Scaffold with Tunable Cavity Sizes and High‐Resolution Structural Detail

Angewandte Chemie
2020-10-12 | Journal article
DOI: 10.1002/ange.202005505
Contributors: Chad R. Simmons; Tara MacCulloch; Fei Zhang; Yan Liu; Nicholas Stephanopoulos; Hao Yan
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A Self‐Assembled Rhombohedral DNA Crystal Scaffold with Tunable Cavity Sizes and High‐Resolution Structural Detail

Angewandte Chemie International Edition
2020-10-12 | Journal article
DOI: 10.1002/anie.202005505
Contributors: Chad R. Simmons; Tara MacCulloch; Fei Zhang; Yan Liu; Nicholas Stephanopoulos; Hao Yan
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Crossref

Correction to Tunable Nanoscale Cages from Self-Assembling DNA and Protein Building Blocks

ACS Nano
2020-06-23 | Journal article
DOI: 10.1021/acsnano.0c02484
Contributors: Yang Xu; Shuoxing Jiang; Chad R. Simmons; Raghu Pradeep Narayanan; Fei Zhang; Ann-Marie Aziz; Hao Yan; Nicholas Stephanopoulos
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Reversible Control of Gelatin Hydrogel Stiffness Using DNA Crosslinkers

2020-06-12 | Other
DOI: 10.26434/chemrxiv.12461918.v1
Contributors: Alex Buchberger; Harpinder Saini; Kiarash Rahmani Eliato; Ryan Merkley; Yang Xu; Azadeh Zare; Julio Bernal; Robert Ros; Mehdi Nikkhah; Nicholas Stephanopoulos
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Crossref

Hierarchical Assembly of Nucleic Acid/Coiled-Coil Peptide Nanostructures

Journal of the American Chemical Society
2020-01-22 | Journal article
DOI: 10.1021/jacs.9b11158
Contributors: Alex Buchberger; Chad R. Simmons; Nour Eddine Fahmi; Ronit Freeman; Nicholas Stephanopoulos
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Crossref

Emerging applications of peptide–oligonucleotide conjugates: bioactive scaffolds, self-assembling systems, and hybrid nanomaterials

Organic & Biomolecular Chemistry
2019 | Journal article
DOI: 10.1039/C8OB02436G
Contributors: Tara MacCulloch; Alex Buchberger; Nicholas Stephanopoulos
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Progress toward sourcing plants for new bioconjugation tools: a screening evaluation of a model peptide ligase using a synthetic precursor

3 Biotech
2019-12 | Journal article
DOI: 10.1007/s13205-019-1983-2
Contributors: Tunjung Mahatmanto; Isyatul Azizah; Alex Buchberger; Nicholas Stephanopoulos
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Crossref

Hierarchical Assembly of DNA Origami Nanostructures Using Coiled-coil Peptides

2019-09-11 | Other
DOI: 10.26434/chemrxiv.9789248.v1
Contributors: Alex Buchberger; Chad Simmons; Nour Fahmi; Ronit Freeman; Nicholas Stephanopoulos
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Crossref

Strategies for Stabilizing DNA Nanostructures to Biological Conditions

ChemBioChem
2019-09-02 | Journal article
DOI: 10.1002/cbic.201900075
Contributors: Nicholas Stephanopoulos
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Peptide–Oligonucleotide Hybrid Molecules for Bioactive Nanomaterials

Bioconjugate Chemistry
2019-07-17 | Journal article
DOI: 10.1021/acs.bioconjchem.9b00259
Contributors: Nicholas Stephanopoulos
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Tunable Nanoscale Cages from Self-Assembling DNA and Protein Building Blocks

ACS Nano
2019-03-26 | Journal article
DOI: 10.1021/acsnano.8b09798
Contributors: Yang Xu; Shuoxing Jiang; Chad R. Simmons; Raghu Pradeep Narayanan; Fei Zhang; Ann-Marie Aziz; Hao Yan; Nicholas Stephanopoulos
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Label-free detection of conformational changes in switchable DNA nanostructures with microwave microfluidics

Nature Communications
2019-03-12 | Journal article
DOI: 10.1038/s41467-019-09017-z
Contributors: Angela C. Stelson; Minghui Liu; Charles A. E. Little; Christian J. Long; Nathan D. Orloff; Nicholas Stephanopoulos; James C. Booth
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Reversible self-assembly of superstructured networks

Science
2018-11-16 | Journal article
DOI: 10.1126/science.aat6141
Contributors: Ronit Freeman; Ming Han; Zaida Álvarez; Jacob A. Lewis; James R. Wester; Nicholas Stephanopoulos; Mark T. McClendon; Cheyenne Lynsky; Jacqueline M. Godbe; Hussain Sangji et al.
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Rapid Photoactuation of a DNA Nanostructure using an Internal Photocaged Trigger Strand

Angewandte Chemie International Edition
2018-07-20 | Journal article
DOI: 10.1002/anie.201804264
Contributors: Minghui Liu; Shuoxing Jiang; Omar Loza; Nour Eddine Fahmi; Petr Šulc; Nicholas Stephanopoulos
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Crossref

Rapid Photoactuation of a DNA Nanostructure using an Internal Photocaged Trigger Strand

Angewandte Chemie
2018-07-20 | Journal article
DOI: 10.1002/ange.201804264
Contributors: Minghui Liu; Shuoxing Jiang; Omar Loza; Nour Eddine Fahmi; Petr Šulc; Nicholas Stephanopoulos
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Peer review (39 reviews for 14 publications/grants)

Review activity for Accounts of chemical research. (1)
Review activity for ACS applied materials & interfaces. (3)
Review activity for ACS central science. (1)
Review activity for ACS nano. (3)
Review activity for Advanced healthcare materials (1)
Review activity for Angewandte Chemie. (5)
Review activity for Bioconjugate chemistry. (1)
Review activity for Biomacromolecules. (3)
Review activity for ChemBioChem. (3)
Review activity for Journal of the American Chemical Society. (11)
Review activity for Langmuir : (2)
Review activity for Nature communications (1)
Review activity for Small. (3)
Review activity for Trends in biotechnology. (1)
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