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University of Bristol profile

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Scopus Author ID: 8140875500

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Employment (5)

The University of Bristol: Bristol, GB

2024-01-03 to present | Academic , Lecturer (School of Biochemistry)
Employment
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University of Bristol - PURE

University of Bristol: Bristol, Bristol, GB

2014-10 to present | CRUK Career Development Fellow (Biochemistry)
Employment
Source: Self-asserted source
Anna Chambers

The University of Bristol: Bristol, GB

2010-09-01 to present | Member (Cancer)
Employment
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University of Bristol - PURE

University of Sussex School of Life Sciences: Brighton, Brighton and Hove, GB

2007-06 to 2014-09 | Postdoctoral Research Assistant (Genome Damage and Stability Centre)
Employment
Source: Self-asserted source
Anna Chambers

University of Cambridge: Cambridge, Cambridgeshire, GB

2005-06 to 2007-05 | Postdoctoral Research Assistant (Biochemistry)
Employment
Source: Self-asserted source
Anna Chambers

Education and qualifications (1)

University of Oxford: Oxford, Oxfordshire, GB

1997-10-06 to 2001-06-22 | MBiochem Molecular and Cellular Biochemistry (Biochemistry)
Education
Source: Self-asserted source
Anna Chambers

Works (23)

Simulation of cell cycle effects on DNA strand break induction due to α-particles

Physica Medica
2025-01 | Journal article
DOI: 10.1016/j.ejmp.2024.104871
Contributors: Laura Ballisat; Chiara De Sio; Lana Beck; Anna L. Chambers; Mark S. Dillingham; Susanna Guatelli; Dousatsu Sakata; Yuyao Shi; Jinyan Duan; Jaap Velthuis et al.
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Crossref
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The human HELLS chromatin remodelling protein promotes end resection to facilitate homologous recombination and contributes to DSB repair within heterochromatin

Nucleic Acids Research
2020-02-28 | Journal article
DOI: 10.1093/nar/gkz1146
Contributors: Gabriel Kollárovič; Caitríona E Topping; Edward P Shaw; Anna L Chambers
Source: check_circle
Crossref
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The human HELLS chromatin remodelling protein promotes end resection to facilitate homologous recombination within heterochromatin

2018-12-21 | Other
DOI: 10.1101/504043
Contributors: G. Kollarovic; C. E. Topping; E. P. Shaw; A. L. Chambers
Source: check_circle
Crossref

Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID

eLife
2017-11-07 | Journal article
DOI: 10.7554/eLife.30395
Contributors: Kapil Gupta; Aleksandra A Watson; Tiago Baptista; Elisabeth Scheer; Anna L Chambers; Christine Koehler; Juan Zou; Ima Obong-Ebong; Eaazhisai Kandiah; Arturo Temblador et al.
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Crossref
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Chapter 11 – Variation, Modification, and Reorganization of Broken Chromatin

Chromatin Signaling and Diseases
2016-10 | Book chapter | Author
SOURCE-WORK-ID:

3638cefc-e86f-4f40-9cb1-4ed4cc07753e
Contributors: Anna Chambers; Jessica Downs; Timothy Humphrey
Source: check_circle
University of Bristol - PURE

Fork rotation and DNA precatenation are restricted during DNA replication to prevent chromosomal instability.

2015-08 | Journal article
DOI: 10.1073/pnas.1505356112
PMID: 26240319
PMC: PMC4547287
Contributors: Schalbetter SA; Mansoubi S; Chambers AL; Downs JA; Baxter J
Source: Self-asserted source
Anna Chambers via Europe PubMed Central
grade
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Requirement for PBAF in transcriptional repression and repair at DNA breaks in actively transcribed regions of chromatin.

2014-09 | Journal article
DOI:

10.1016/j.molcel.2014.06.028

PMID:

25066234

PMC:

PMC4157577
Contributors: Kakarougkas A; Ismail A; Chambers AL; Riballo E; Herbert AD; Künzel J; Löbrich M; Jeggo PA; Downs JA
Source: Self-asserted source
Anna Chambers via Europe PubMed Central
grade
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BAF180 promotes cohesion and prevents genome instability and aneuploidy.

2014-03 | Journal article
DOI:

10.1016/j.celrep.2014.02.012

PMID:

24613357

PMC:

PMC3988838
Contributors: Brownlee PM; Chambers AL; Cloney R; Bianchi A; Downs JA
Source: Self-asserted source
Anna Chambers via Europe PubMed Central
grade
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The BAH domain of Rsc2 is a histone H3 binding domain.

2013-10 | Journal article
DOI:

10.1093/nar/gkt662

PMID:

23907388

PMC:

PMC3799432
Contributors: Chambers AL; Pearl LH; Oliver AW; Downs JA
Source: Self-asserted source
Anna Chambers via Europe PubMed Central
grade
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The RSC and INO80 chromatin-remodeling complexes in DNA double-strand break repair.

2012 | Journal article
DOI:

10.1016/B978-0-12-387665-2.00009-2

PMID:

22749148
Contributors: Chambers AL; Downs JA
Source: Self-asserted source
Anna Chambers via Europe PubMed Central
grade
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The two different isoforms of the RSC chromatin remodeling complex play distinct roles in DNA damage responses.

2012 | Journal article
DOI:

10.1371/journal.pone.0032016

PMID:

22359657

PMC:

PMC3281108
Contributors: Chambers AL; Brownlee PM; Durley SC; Beacham T; Kent NA; Downs JA
Source: Self-asserted source
Anna Chambers via Europe PubMed Central
grade
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The INO80 chromatin remodeling complex prevents polyploidy and maintains normal chromatin structure at centromeres.

2012-12 | Journal article
DOI:

10.1101/gad.199976.112

PMID:

23207916

PMC:

PMC3521627
Contributors: Chambers AL; Ormerod G; Durley SC; Sing TL; Brown GW; Kent NA; Downs JA
Source: Self-asserted source
Anna Chambers via Europe PubMed Central
grade
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A role for chromatin remodellers in replication of damaged DNA.

2012-08 | Journal article
DOI:

10.1093/nar/gks453

PMID:

22638582

PMC:

PMC3424576
Contributors: Niimi A; Chambers AL; Downs JA; Lehmann AR
Source: Self-asserted source
Anna Chambers via Europe PubMed Central
grade
Preferred source (of 2)‎

Cancer and the bromodomains of BAF180.

2012-04 | Journal article
DOI:

10.1042/BST20110754

PMID:

22435813
Contributors: Brownlee PM; Chambers AL; Oliver AW; Downs JA
Source: Self-asserted source
Anna Chambers via Europe PubMed Central
grade
Preferred source (of 2)‎

Faculty of 1000 evaluation for Elevated histone expression promotes life span extension.

F1000 - Post-publication peer review of the biomedical literature
2010-09 | Dataset
DOI: 10.3410/f.5338957.5287064
Contributors: Jessica Downs; Anna Chambers
Source: Self-asserted source
Anna Chambers via Crossref Metadata Search

Faculty of 1000 evaluation for Abundance of ribosomal RNA gene copies maintains genome integrity.

F1000 - Post-publication peer review of the biomedical literature
2010-02 | Dataset
DOI: 10.3410/f.1977958.1570056
Contributors: Jessica Downs; Anna Chambers
Source: Self-asserted source
Anna Chambers via Crossref Metadata Search

Faculty of 1000 evaluation for Recombinational repair within heterochromatin requires ATP-dependent chromatin remodeling.

F1000 - Post-publication peer review of the biomedical literature
2009-10-05 | Dataset
DOI: 10.3410/f.1165159.628077
Contributors: Jessica Downs; Anna Chambers
Source: Self-asserted source
Anna Chambers via Crossref Metadata Search

The contribution of the budding yeast histone H2A C-terminal tail to DNA-damage responses

Biochemical Society Transactions
2007-12 | Journal article | Author
DOI: 10.1042/BST0351519
SOURCE-WORK-ID:

5042fe14-34d5-4fb6-b094-eac4ad20e5ba

PMID: 18031258
EID:

2-s2.0-37749030970
Contributors: Anna Chambers; J A Downs
Source: check_circle
University of Bristol - PURE

Dual chromatin remodeling roles for RSC during DNA double strand break induction and repair at the yeast MAT locus.

2007-09 | Journal article
DOI:

10.1074/jbc.M704707200

PMID:

17652077
Contributors: Kent NA; Chambers AL; Downs JA
Source: Self-asserted source
Anna Chambers via Europe PubMed Central
grade
Preferred source (of 2)‎

Structural basis for bacterial transcription-coupled DNA repair.

2006-02 | Journal article
DOI:

10.1016/j.cell.2005.11.045

PMID:

16469698
Contributors: Deaconescu AM; Chambers AL; Smith AJ; Nickels BE; Hochschild A; Savery NJ; Darst SA
Source: Self-asserted source
Anna Chambers via Europe PubMed Central
grade
Preferred source (of 2)‎

A DNA translocation motif in the bacterial transcription--repair coupling factor, Mfd.

2003-11 | Journal article
DOI:

10.1093/nar/gkg868

PMID:

14602898

PMC:

PMC275562
Contributors: Chambers AL; Smith AJ; Savery NJ
Source: Self-asserted source
Anna Chambers via Europe PubMed Central
grade
Preferred source (of 2)‎

Two aromatic residues in the PB2 subunit of influenza A RNA polymerase are crucial for cap binding.

2003-05 | Journal article
DOI:

10.1074/jbc.M300130200

PMID:

12646557
Contributors: Fechter P; Mingay L; Sharps J; Chambers A; Fodor E; Brownlee GG
Source: Self-asserted source
Anna Chambers via Europe PubMed Central
grade
Preferred source (of 2)‎

Transcription termination by a trancription-repair coupling factor.

Supervised student publication
OTHER-ID:

412357
Contributors: Chambers AL
Source: Self-asserted source
Anna Chambers via Europe PubMed Central
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