Personal information
Biography
I completed my PhD in biochemistry in the Department of Biochemistry and Molecular Biology at University of Seville (Spain), where I focused on the effect of aging and oxidative stress on protein synthesis through alterations of translation eElongation Factor-2 (eEF2), as well as the protection of eEF2 using several antioxidant and protective compounds such as melatonin. After completed my PhD in 2007, I worked on the role of stress and inflammation in neurodegenerative diseases. I moved to United Stares in 2010, where I worked on neuronal survival and regulatory mechanisms of eEF2 in neurons experiencing stress (Prof. Mark Matsson´s Laboratory of Neurosciences at the NIA in the Johns Hopkins Bayview Campus, in Baltimore, Maryland). In 2012, I was selected and sponsored with funds from the NIA to participate in the Twentieth Annual Summer Training Course in Experimental Aging Research. The Buck Institute for Research on Aging administers this annual NIA-sponsored Summer Training Course. Aging is a complex, multi-factorial process characterized by the progressive decline in the efficiency of various physiological functions. In general, cell stress mechanisms, biological aging and neuronal death are related to neurological problems in old age. I have strong Biochemistry and Cellular & Molecular Neuroscience background in oxidative stress and aging. The age-population is expected to increase during the next several decades, and due age is a major risk factor for most cancers, a large increase in the number of patients with cancer is anticipated. I moved to China in 2015, with the aim of study pathways that can be modified to mitigate basic aging processes and could be potentially important for tumor development, tumor suppression and the response to therapy. I worked on the role of signal transduction in carcinogenesis and molecular mechanisms of cancer prevention (Prof. Zigang Dong’s laboratory of Cellular and Molecular Biology at China-US Hormel Cancer Institute) using different molecular biology and bioinformatics tools. In 2016, I started a postdoctoral research appointment in the Department of Physiology at University of Seville (Spain), and in 2019 I got a fulltime professor position. My research aim is to address the challenge of aging and adults' health and quality of life in the old age.
Activities
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Works (50 of 54)
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