Personal information

Other IDs

ResearcherID: C-8232-2017
Scopus Author ID: 56716539500

Keywords

Colorectal cancer, DNA repair, Biomarkers

Countries

Czech Republic

Biography

My primary research interests lie in the field of enzyme biotechnology, particularly the development and characterization of microbial enzymes for plastic biodegradation. I am currently working on the optimization of expression and purification protocols for PET-degrading enzymes, with the aim of establishing standardized workflows that reduce variability and improve reproducibility in enzymatic PET degradation studies. My research also focuses on benchmarking the activity of PETase variants and contributing to the engineering of more efficient enzymes for sustainable plastic recycling applications.

Activities

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Employment (4)

Institute of Organic Chemistry and Biochemistry: Prague, CZ

2020-11-01 to present | Research fellow (Bioinformatics)
Employment
Source: Self-asserted source
Katerina Jiraskova

Institute of Biology and Medical Genetics, First Faculty of Medicine: Prague, CZ

2013 to 2019-12-31 | Research assistant
Employment
Source: Self-asserted source
Katerina Jiraskova

Institute of Experimental Medicine AS CR: Prague, CZ

2012 to 2019-12-31 | PhD student, Research assistant (Department of the Molecular Biology of Cancer)
Employment
Source: Self-asserted source
Katerina Jiraskova

The Institute of Hematology and Blood Transfusion: Prague, CZ

2004 to 2007 | Diploma student (Laboratory for DNA Diagnostics)
Employment
Source: Self-asserted source
Katerina Jiraskova

Education and qualifications (2)

Charles University, First Faculty of Medicine: Prague, CZ

2012 to 2020-02-07 | PhD (Molecular and Cellular Biology, Genetics and Virology)
Education
Source: Self-asserted source
Katerina Jiraskova

Charles University, Faculty of Science in Prague: Prague, CZ

2002-10 to 2007-09 | Master's degree (Genetics and Microbiology)
Education
Source: Self-asserted source
Katerina Jiraskova

Funding (1)

Non-synonymous functional variants in DNA repair genes in sporadic colorectal cancer: searching for predictive and prognostic marker

2015 to 2017 | Grant
Grant Agency of Charles University (Prague, CZ)
GRANT_NUMBER:

GAUK 112515
Source: Self-asserted source
Katerina Jiraskova

Works (22)

Interaction of Calmodulin with TRPM: An Initiator of Channel Modulation

International Journal of Molecular Sciences
2023-10 | Journal article | Author
DOI: 10.3390/ijms242015162
Contributors: Kristyna Vydra Bousova; Monika Zouharova; Katerina Jiraskova; Veronika Vetýšková
Source: check_circle
Multidisciplinary Digital Publishing Institute

TRPM5 Channel Binds Calcium-Binding Proteins Calmodulin and S100A1

Biochemistry
2022-03-15 | Journal article
DOI: 10.1021/acs.biochem.1c00647
Part of ISSN: 0006-2960
Part of ISSN: 1520-4995
Contributors: Kristyna Vydra Bousova; Monika Zouharova; Petr Herman; Jiří Vymětal; Veronika Vetyskova; Katerina Jiraskova; jiri vondrasek
Source: Self-asserted source
Katerina Jiraskova

TRPM7 N-terminal region forms complexes with calcium binding proteins CaM and S100A1

Heliyon
2021-12 | Journal article | Author
DOI: 10.1016/j.heliyon.2021.e08490
Part of ISSN: 2405-8440
Contributors: Kristyna Vydra Bousova; Monika Zouharova; Petr Herman; Veronika Vetýšková; Katerina Jiraskova; Jiri Vondrasek
Source: Self-asserted source
Katerina Jiraskova

Epistatic effect of TLR3 and cGAS‐STING‐IKKε‐TBK1‐IFN signaling variants on colorectal cancer risk

Cancer Medicine
2020-02 | Journal article
DOI: 10.1002/cam4.2804
Part of ISSN: 2045-7634
Part of ISSN: 2045-7634
Source: Self-asserted source
Katerina Jiraskova

Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon

Cell Death & Disease
2019-11 | Journal article
DOI: 10.1038/s41419-019-2057-4
Part of ISSN: 2041-4889
Source: Self-asserted source
Katerina Jiraskova

Fusobacterium nucleatum tumor DNA levels are associated with survival in colorectal cancer patients

European Journal of Clinical Microbiology & Infectious Diseases
2019-10 | Journal article
DOI: 10.1007/s10096-019-03649-1
Part of ISSN: 0934-9723
Part of ISSN: 1435-4373
Source: Self-asserted source
Katerina Jiraskova

Relationship of telomere length in colorectal cancer patients with cancer phenotype and patient prognosis

British Journal of Cancer
2019-08 | Journal article
DOI: 10.1038/s41416-019-0525-3
Part of ISSN: 0007-0920
Part of ISSN: 1532-1827
Source: Self-asserted source
Katerina Jiraskova

Base excision repair capacity as a determinant of prognosis and therapy response in colon cancer patients

DNA Repair
2018-12 | Journal article
DOI: 10.1016/j.dnarep.2018.09.006
Part of ISSN: 1568-7864
Source: Self-asserted source
Katerina Jiraskova

Functional Polymorphisms in DNA Repair Genes Are Associated with Sporadic Colorectal Cancer Susceptibility and Clinical Outcome

International Journal of Molecular Sciences
2018-12 | Journal article | Author
DOI: 10.3390/ijms20010097
Contributors: Katerina Jiraskova; David J. Hughes; Stefanie Brezina; Tanja Gumpenberger; Veronika Veskrnova; Tomas Buchler; Michaela Schneiderova; Miroslav Levy; Vaclav Liska; Sona Vodenkova et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

Expression profile of miR-17/92 cluster is predictive of treatment response in rectal cancer

Carcinogenesis
2018-12-13 | Journal article
DOI: 10.1093/carcin/bgy100
Part of ISSN: 0143-3334
Part of ISSN: 1460-2180
Source: Self-asserted source
Katerina Jiraskova

Short article: Influence of regulatory NLRC5 variants on colorectal cancer survival and 5-fluorouracil-based chemotherapy

European Journal of Gastroenterology & Hepatology
2018-08 | Journal article
DOI: 10.1097/meg.0000000000001154
Part of ISSN: 0954-691X
Source: Self-asserted source
Katerina Jiraskova

Coding variants in NOD-like receptors: An association study on risk and survival of colorectal cancer

PLOS ONE
2018-06-21 | Journal article
DOI: 10.1371/journal.pone.0199350
Part of ISSN: 1932-6203
Source: Self-asserted source
Katerina Jiraskova

Bleomycin‐induced chromosomal damage and shortening of telomeres in peripheral blood lymphocytes of incident cancer patients

Genes, Chromosomes and Cancer
2018-02 | Journal article
DOI: 10.1002/gcc.22508
Part of ISSN: 1045-2257
Part of ISSN: 1098-2264
Source: Self-asserted source
Katerina Jiraskova

Investigation of single and synergic effects of NLRC5 and PD-L1 variants on the risk of colorectal cancer

PLOS ONE
2018-02-06 | Journal article
DOI: 10.1371/journal.pone.0192385
Part of ISSN: 1932-6203
Source: Self-asserted source
Katerina Jiraskova

Association between taste receptor (TAS) genes and the perception of wine characteristics

Scientific Reports
2017-12 | Journal article
DOI: 10.1038/s41598-017-08946-3
Part of ISSN: 2045-2322
Source: Self-asserted source
Katerina Jiraskova

MicroRNA-binding site polymorphisms in genes involved in colorectal cancer etiopathogenesis and their impact on disease prognosis

Mutagenesis
2017-10-17 | Journal article
DOI: 10.1093/mutage/gex026
Part of ISSN: 0267-8357
Part of ISSN: 1464-3804
Source: Self-asserted source
Katerina Jiraskova

Double-strand break repair and colorectal cancer: gene variants within 3 ' UTRs and microRNAs binding as modulators of cancer risk and clinical outcome

Oncotarget
2016 | Journal article
DOI: 10.18632/oncotarget.6804
WOSUID:

WOS:000377706200015
Contributors: Naccarati, Alessio; Rosa, Fabio; Vymetalkova, Veronika; Barone, Elisa; Jiraskova, Katerina; Di Gaetano, Cornelia; Novotny, Jan; Levy, Miroslav; Vodickova, Ludmila; Gemignani, Federica et al.
Source: Self-asserted source
Katerina Jiraskova via ResearcherID
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Nonsynonymous functional variants in DNA repair genes in sporadic colorectal cancer: searching for predictive and prognostic markers

Cancer Research
2016 | Journal article
DOI: 10.1158/1538-7445.AM2016-3409
WOSUID:

WOS:000389940604163
Contributors: Jiraskova, Katerina; Slyskova, Jana; Rosa, Fabio; Di Gaetano, Cornelia; Pardini, Barbara; Vymetalkova, Veronika; Vodicka, Pavel
Source: Self-asserted source
Katerina Jiraskova via ResearcherID

Polymorphisms in microRNA binding sites of mucin genes as predictors of clinical outcome in colorectal cancer patients.

Carcinogenesis
2016 | Journal article
WOSUID:

MEDLINE:27803053
Contributors: Vymetalkova, Veronika; Pardini, Barbara; Rosa, Fabio; Jiraskova, Katerina; Di Gaetano, Cornelia; Bendova, Petra; Levy, Miloslav; Veskrnova, Veronika; Buchler, Tomas; Vodickova, Ludmila et al.
Source: Self-asserted source
Katerina Jiraskova via ResearcherID

Genotype and Haplotype Analyses of TP53 Gene in Breast Cancer Patients: Association with Risk and Clinical Outcomes

Plos One
2015 | Journal article
DOI: 10.1371/journal.pone.0134463
WOSUID:

WOS:000358837700096
Contributors: Vymetalkova, Veronika; Soucek, Pavel; Kunicka, Tereza; Jiraskova, Katerina; Brynychova, Veronika; Pardini, Barbara; Novosadova, Vendula; Polivkova, Zdena; Kubackova, Katerina; Kozevnikovova, Renata et al.
Source: Self-asserted source
Katerina Jiraskova via ResearcherID
grade
Preferred source (of 2)‎

Interactions of DNA repair gene variants modulate chromosomal aberrations in healthy subjects

Carcinogenesis
2015 | Journal article
DOI: 10.1093/carcin/bgv127
WOSUID:

WOS:000366386800006
Contributors: Vodicka, Pavel; Musak, Ludovit; Frank, Christoph; Kazimirova, Alena; Vymetalkova, Veronika; Barancokova, Magdalena; Smolkova, Bozena; Dzupinkova, Zuzana; Jiraskova, Katerina; Vodenkova, Sona et al.
Source: Self-asserted source
Katerina Jiraskova via ResearcherID
grade
Preferred source (of 2)‎

Structural chromosomal aberrations as potential risk markers in incident cancer patients

Mutagenesis
2015 | Journal article
DOI: 10.1093/mutage/gev018
WOSUID:

WOS:000357885900011
Contributors: Vodenkova, Sona; Polivkova, Zdenka; Musak, Ludovit; Smerhovsky, Zdenek; Zoubkova, Hana; Sytarova, Sylvie; Kavcova, Elena; Halasova, Erika; Vodickova, Ludmila; Jiraskova, Katerina et al.
Source: Self-asserted source
Katerina Jiraskova via ResearcherID
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