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Other IDs

ResearcherID: E-7517-2011

Keywords

Cancer, Leukemia, AML, Functional genetics, RNAi, CRISPR, Genetic screening, Mouse models, BRD4, BET inhibitors, Aberrant self-renewal

Countries

Austria

Activities

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Employment (6)

Research Institute of Molecular Pathology: Vienna, AT

2020-01-01 to present | Senior Group Leader
Employment
Source: Self-asserted source
Johannes Zuber

Medical University of Vienna: Vienna, AT

2017-09-19 to present | Adjunct Professor
Employment
Source: Self-asserted source
Johannes Zuber

Research Institute of Molecular Pathology (IMP): Vienna, AT

2011 to 2019 | Group Leader / PI (Zuberlab)
Employment
Source: Self-asserted source
Johannes Zuber

Cold Spring Harbor Laboratory: Cold Spring Harbor, NY, US

2009 to 2010 | Clinical Research Fellow (Scott Lowe Lab)
Employment
Source: Self-asserted source
Johannes Zuber

Cold Spring Harbor Laboratory: Cold Spring Harbor, NY, US

2005 to 2008 | Postdoc (Scott Lowe Lab)
Employment
Source: Self-asserted source
Johannes Zuber

Charite Universitatsmedizin Berlin Campus Virchow-Klinikum: Berlin, Berlin, DE

2001 to 2005 | Resident MD (Hematology / Oncology)
Employment
Source: Self-asserted source
Johannes Zuber

Education and qualifications (2)

Charite, Institut für Pathologie: Berlin, Berlin, DE

1997 to 2003 | Dr. med. (Molecular Tumor Pathology)
Education
Source: Self-asserted source
Johannes Zuber

Humboldt-Universität zu Berlin: Berlin, Berlin, DE

1993 to 2001 | MD (Charite)
Education
Source: Self-asserted source
Johannes Zuber

Professional activities (4)

European Hematology Association: Den Haag, NL

2022-07 to present | Fellowships and Grants Comittee
Membership
Source: Self-asserted source
Johannes Zuber

EMBO: Heidelberg, DE

2022-07 to present | Full Member
Membership
Source: Self-asserted source
Johannes Zuber

Deutsche Krebsgesellschaft (DKG): Berlin, DE

2018 to present | Deputy Speaker Biochemistry (Experimental Cancer Research (AEK))
Membership
Source: Self-asserted source
Johannes Zuber

EMBO: Heidelberg, DE

2015 to 2018 | Young Investigator (YIP)
Membership
Source: Self-asserted source
Johannes Zuber

Funding (10)

Deciphering bone marrow stroma-induced resistance to targeted therapies in T-cell acute lymphoblastic leukemia using functional genetics.

2021-01-01 to present | Grant
Deutsche Forschungsgemeinschaft (Bonn, DE)
URL: https://app.dimensions.ai/details/grant/grant.10023845
GRANT_NUMBER: 471798038
Source: Self-asserted source
Johannes Zuber via DimensionsWizard

Entwicklung sensitiver und skalierbarer Screening-Assays zur Überwachung von COVID-19-Infektionen im Populationsmaßstab

2020-04-01 to 2021-03-31 | Grant
Vienna Science and Technology Fund (Vienna, AT)
URL: https://app.dimensions.ai/details/grant/grant.9488985
GRANT_NUMBER: EI-COV20-031
Source: Self-asserted source
Johannes Zuber via DimensionsWizard

Diagnostic drug response-profiling using SLAMseq

2019-10-01 to 2021-03-31 | Grant
European Research Council (Brussels, BE)
URL: https://app.dimensions.ai/details/grant/grant.8587618
GRANT_NUMBER: 862507
Source: Self-asserted source
Johannes Zuber via DimensionsWizard

Overcoming the differentiation block in acute myeloid leukaemia

2017-01-01 to 2020-12-31 | Grant
National Health and Medical Research Council (Canberra, AU)
URL: https://app.dimensions.ai/details/grant/grant.7877444
GRANT_NUMBER: 1121765
Source: Self-asserted source
Johannes Zuber via DimensionsWizard

Finding and probing cancer drug targets using advanced in-vivo RNAi

2015-07-04 to 2017-07-04 | Grant
European Molecular Biology Organization (Heidelberg, DE)
URL: https://app.dimensions.ai/details/grant/grant.6918386
GRANT_NUMBER:

1e5ef4f1
Source: Self-asserted source
Johannes Zuber via DimensionsWizard

EMBO Young Investigator

2015 to 2018 | Award
European Molecular Biology Organization (Heidelberg, DE)
Source: Self-asserted source
Johannes Zuber

Systematic in-vivo analysis of chromatin-associated targets in leukemia

2014-01-01 to 2018-12-31 | Grant
European Research Council (Saint-Josse-ten-Noode, BE)
URL: https://grants.uberresearch.com/501100000781/110735/Systematic-in-vivo-analysis-of-chromatin-associated-targets-in-leukemia
GRANT_NUMBER: 336860
Source: Self-asserted source
Johannes Zuber via DimensionsWizard

Tumour suppressive mechanisms of CEBP? and PU.1 in acute myeloid leukemia

2014-01-01 to 2016-12-31 | Grant
National Health and Medical Research Council (Canberra, AU)
URL: https://app.dimensions.ai/details/grant/grant.6730594
GRANT_NUMBER: 1057854
Source: Self-asserted source
Johannes Zuber via DimensionsWizard

SFB Myeloproliverative Neoplasien

2013 to 2017 | Grant
FWF Austrian Science Fund (Vienna, AT)
GRANT_NUMBER: F4710
Source: Self-asserted source
Johannes Zuber

In vivo analysis of key genes and resistance mechanisms in the treatment of acute myeloid leukemia

Source: Self-asserted source
Johannes Zuber via DimensionsWizard

Works (50 of 288)

Items per page:
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ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia

Nature Communications
2023-09-19 | Journal article
DOI: 10.1038/s41467-023-41229-2
Contributors: Jessica Ebner; Johannes Schmoellerl; Martin Piontek; Gabriele Manhart; Selina Troester; Bing Z. Carter; Heidi Neubauer; Richard Moriggl; Gergely Szakács; Johannes Zuber et al.
Source: check_circle
Crossref

A rapid, highly sensitive and open-access SARS-CoV-2 detection assay for laboratory and home testing

Frontiers in molecular biosciences
2022 | Journal article
Source: Self-asserted source
Johannes Zuber

BRD4 degradation blocks expression of MYC and multiple forms of stem cell resistance in Ph+ chronic myeloid leukemia

American journal of hematology
2022 | Journal article
Source: Self-asserted source
Johannes Zuber

Comprehensive CRISPR-Cas9 screen identifies factors which are important for plasmablast development

Frontiers in Immunology
2022 | Journal article
Source: Self-asserted source
Johannes Zuber

Different Gene Sets Are Associated With Azacitidine Response In Vitro Versus in Myelodysplastic Syndrome Patients

HemaSphere
2022 | Journal article
Source: Self-asserted source
Johannes Zuber

Discovery of potent and selective HER2 inhibitors with efficacy against HER2 exon 20 insertion-driven tumors, which preserve wild-type EGFR signaling

Nature Cancer
2022 | Journal article
Source: Self-asserted source
Johannes Zuber

DNA sequence and chromatin modifiers cooperate to confer epigenetic bistability at imprinting control regions

Nature Genetics
2022 | Journal article
Source: Self-asserted source
Johannes Zuber

Dysregulated RNA polyadenylation contributes to metabolic impairment in non-alcoholic fatty liver disease

Nucleic acids research
2022 | Journal article
Source: Self-asserted source
Johannes Zuber

EVI1 drives leukemogenesis through aberrant ERG activation

Blood
2022 | Journal article
Source: Self-asserted source
Johannes Zuber

HUWE1 controls tristetraprolin proteasomal degradation by regulating its phosphorylation

bioRxiv
2022 | Journal article
Source: Self-asserted source
Johannes Zuber

Identification of direct target genes of NUP98-KDM5A reveals regulatory gene networks in Acute Myeloid Leukemia

Klinische Pädiatrie
2022 | Journal article
Source: Self-asserted source
Johannes Zuber

Lysosomal enzyme trafficking factor LYSET enables nutritional usage of extracellular proteins

Science
2022 | Journal article
Source: Self-asserted source
Johannes Zuber

S117: EVI1 DRIVES LEUKEMOGENESIS THROUGH ABERRANT ERG ACTIVATION

HemaSphere
2022 | Journal article
Source: Self-asserted source
Johannes Zuber

S118: IDENTIFICATION OF DIRECT TRANSCRIPTIONAL TARGET GENES OF NUP98-KDM5A REVEALS REGULATORY NETWORKS IN ACUTE MYELOID LEUKEMIA

HemaSphere
2022 | Journal article
Source: Self-asserted source
Johannes Zuber

S227: SBNO2 IS A SPECIFIC DEPENDENCY OF STAT3-DRIVEN T-CELL MALIGNANCIES

HemaSphere
2022 | Journal article
Source: Self-asserted source
Johannes Zuber

SPOP targets the immune transcription factor IRF1 for proteasomal degradation

bioRxiv
2022 | Journal article
Source: Self-asserted source
Johannes Zuber

Vienna COVID-19 Detection Initiative (VCDI), Pauli A and Brennecke J (2022) A Rapid, Highly Sensitive and Open-Access SARS-CoV-2 Detection Assay for Laboratory and Home Testing

Front. Mol. Biosci. 9: 801309. doi: 10.3389/fmolb
2022 | Journal article
Source: Self-asserted source
Johannes Zuber

Nucleic acid modification and identification method

2022-04 | Other
Source: Self-asserted source
Johannes Zuber

A functional LSD1 coregulator screen reveals a novel transcriptional regulatory cascade connecting R-loop homeostasis with epigenetic regulation

Nucleic acids research
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

A functional LSD1 coregulator screen reveals a novel transcriptional regulatory cascade connecting R-loop homeostasis with epigenetic regulation

Nucleic acids research
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

A genome-wide CRISPR/Cas9 screen to identify phagocytosis modulators in monocytic THP-1 cells

Scientific Reports
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

A genome-wide CRISPR/Cas9 screen to identify phagocytosis modulators in monocytic THP-1 cells

Scientific reports
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumor microenvironment and cross-resistance to immunotherapy in melanoma

Nature Cancer
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumor microenvironment and cross-resistance to immunotherapy in melanoma

Nature Cancer
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

AKIRIN2 controls the nuclear import of proteasomes in vertebrates

Nature
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

AKIRIN2 controls the nuclear import of proteasomes in vertebrates

Nature
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Core binding factor leukemia hijacks T-cell prone PU. 1 antisense promoter

Blood
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Core-binding factor leukemia hijacks the T-cell--prone PU. 1 antisense promoter

blood
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Functional analysis of non-genetic resistance to platinum in epithelial ovarian cancer reveals a role for the MBD3-NuRD complex in resistance development

Cancers
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Functional analysis of non-genetic resistance to platinum in epithelial ovarian cancer reveals a role for the MBD3-NuRD complex in resistance development

Cancers
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors

Cell Host & Microbe
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors

Cell host & microbe
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Head-to-head comparison of direct-input RT-PCR and RT-LAMP against RT-qPCR on extracted RNA for rapid SARS-CoV-2 diagnostics

MedRxiv
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Head-to-head comparison of direct-input RT-PCR and RT-LAMP against RTqPCR on extracted RNA for rapid SARS-CoV-2 diagnostics

medRxiv
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Inhibition of CBP synergizes with the RNA-dependent mechanisms of Azacitidine by limiting protein synthesis

Nature Communications
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Inhibition of CBP synergizes with the RNA-dependent mechanisms of Azacitidine by limiting protein synthesis

Nature communications
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Precision medicine in hematology 2021: definitions, tools, perspectives, and open questions

Hemasphere
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Precision medicine in hematology 2021: definitions, tools, perspectives, and open questions

Hemasphere
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Prevalence of RT-qPCR-detected SARS-CoV-2 infection at schools: First results from the Austrian School-SARS-CoV-2 prospective cohort study

The Lancet Regional Health-Europe
2021 | Journal article
DOI: 10.1101/2021.01.05.20248952
Source: Self-asserted source
Johannes Zuber

Publisher Correction: Rational discovery of molecular glue degraders via scalable chemical profiling

Nature Chemical Biology
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Results of WICOVIR Gargle Pool PCR Testing in German Schools Based on the First 100,000 Tests

Frontiers in Pediatrics
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Results of WICOVIR Gargle Pool PCR Testing in German Schools Based on the First 100,000 Tests

Frontiers in pediatrics
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Selective requirement of MYB for oncogenic hyperactivation of a translocated enhancer in leukemia

Cancer Discovery
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Selective requirement of MYB for oncogenic hyperactivation of a translocated enhancer in leukemia

Cancer discovery
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021

Eurosurveillance
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021

Eurosurveillance
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters

Molecular Cell
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters

Molecular Cell
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

XPO7 is a tumor suppressor regulating p21CIP1-dependent senescence

Genes & development
2021 | Journal article
Source: Self-asserted source
Johannes Zuber

XPO7 is a tumor suppressor regulating p21CIP1-dependent senescence

Genes & development
2021 | Journal article
Source: Self-asserted source
Johannes Zuber
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