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Employment (1)

Van Andel Research Institute: Grand Rapids, MI, US

2015 to present
Employment
Source: Self-asserted source
Gerhard Coetzee

Education and qualifications (4)

Stellenbosch University: Stellenbosch, Western Cape, ZA

1977 | PhD (Medical Biochemistry)
Education
Source: Self-asserted source
Gerhard Coetzee

Stellenbosch University: Stellenbosch, Western Cape, ZA

1973 | Master of Science cum laude (Medical Biochemistry)
Education
Source: Self-asserted source
Gerhard Coetzee

North-West University: Potchefstroom, ZA

1972 | Bachelor of Science with distinction (Biochemistry)
Education
Source: Self-asserted source
Gerhard Coetzee

North-West University: Potchefstroom, ZA

1971 | Bachelor of Science with distinction (Chemistry and Physiology)
Education
Source: Self-asserted source
Gerhard Coetzee

Works (50 of 198)

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Page 1 of 4

Gene expression asymmetry in Parkinson’s Disease; variation ofCCTandBEXgene expression levels are correlated with hemisphere specific severity

2024-07-04 | Preprint
DOI: 10.1101/2024.07.02.601704
Contributors: Steven E. Pierce; Edwin J.C. van der Schans; Elizabeth Ensink; Gerhard A. Coetzee
Source: check_circle
Crossref

Global Effects of a PD Risk-SNP at the Alpha-Synuclein Locus

2021-07-08 | Other
DOI: 10.1101/2021.07.06.451330
Contributors: Jordan Prahl; Steven E. Pierce; Edwin JC van der Schans; Gerhard A. Coetzee; Trevor Tyson
Source: check_circle
Crossref

Post-GWAS knowledge gap: the how, where, and when.

NPJ Parkinson's disease
2020-09 | Journal article
DOI: 10.1038/s41531-020-00125-y
PMID: 32964108
PMC: PMC7481221
Contributors: Pierce SE; Booms A; Prahl J; van der Schans EJC; Tyson T; Coetzee GA
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central
grade
Preferred source (of 2)‎

Epigenomic analysis of Parkinson's disease neurons identifies Tet2 loss as neuroprotective.

Nature neuroscience
2020-08 | Journal article
DOI: 10.1038/s41593-020-0690-y
PMID: 32807949
Contributors: Marshall LL; Killinger BA; Ensink E; Li P; Li KX; Cui W; Lubben N; Weiland M; Wang X; Gordevicius J et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Parkinson’s Disease Genetic Risk Evaluation in Microglia Highlights Autophagy and Lysosomal Genes

2020-08 | Other
DOI: 10.1101/2020.08.17.254276
OTHER-ID:

PPR202259
Contributors: Booms A; Pierce SE; Coetzee GA
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central
grade
Preferred source (of 2)‎

Understanding Non-Mendelian Genetic Risk.

Current genomics
2019-08 | Journal article
DOI: 10.2174/1389202920666191018085511
PMID: 32476988
PMC: PMC7235392
Contributors: Coetzee GA
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Genetically engineered stem cell-derived neurons can be rendered resistant to alpha-synuclein aggregate pathology.

The European journal of neuroscience
2019-01 | Journal article
DOI: 10.1111/ejn.14333
PMID: 30614081
Contributors: Brundin P; Coetzee GA
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

CRISPR-mediated deletion of prostate cancer risk-associated CTCF loop anchors identifies repressive chromatin loops.

Genome biology
2018-10 | Journal article
DOI: 10.1186/s13059-018-1531-0
PMID: 30296942
PMC: PMC6176514
Contributors: Guo Y; Perez AA; Hazelett DJ; Coetzee GA; Rhie SK; Farnham PJ
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Parkinson's disease genetic risk in a midbrain neuronal cell line.

Neurobiology of disease
2018-02 | Journal article
DOI: 10.1016/j.nbd.2018.02.007
PMID: 29486295
Contributors: Pierce SE; Tyson T; Booms A; Prahl J; Coetzee GA
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

The Five Dimensions of Parkinson's Disease Genetic Risk.

Journal of Parkinson's disease
2018-01 | Journal article
DOI: 10.3233/jpd-171256
PMID: 29254107
Contributors: Coetzee GA; Pierce S
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Parkinson's disease-associated genetic variation is linked to quantitative expression of inflammatory genes.

PloS one
2017-04 | Journal article
DOI: 10.1371/journal.pone.0175882
PMID: 28407015
PMC: PMC5391096
Contributors: Pierce S; Coetzee GA
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
2016-10 | Journal article
DOI: 10.1158/1055-9965.epi-16-0106
PMID: 27697780
PMC: PMC5224974
Contributors: Amos CI; Dennis J; Wang Z; Byun J; Schumacher FR; Gayther SA; Casey G; Hunter DJ; Sellers TA; Gruber SB et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Enrichment of risk SNPs in regulatory regions implicate diverse tissues in Parkinson's disease etiology.

Scientific reports
2016-07 | Journal article
DOI: 10.1038/srep30509
PMID: 27461410
PMC: PMC4962314
Contributors: Coetzee SG; Pierce S; Brundin P; Brundin L; Hazelett DJ; Coetzee GA
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

4C-seq revealed long-range interactions of a functional enhancer at the 8q24 prostate cancer risk locus.

Scientific reports
2016-03 | Journal article
DOI: 10.1038/srep22462
PMID: 26934861
PMC: PMC4776156
Contributors: Cai M; Kim S; Wang K; Farnham PJ; Coetzee GA; Lu W
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Prostate Cancer Susceptibility in Men of African Ancestry at 8q24.

Journal of the National Cancer Institute
2016-01 | Journal article
DOI: 10.1093/jnci/djv431
PMID: 26823525
PMC: PMC4948565
Contributors: Han Y; Rand KA; Hazelett DJ; Ingles SA; Kittles RA; Strom SS; Rybicki BA; Nemesure B; Isaacs WB; Stanford JL et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Reducing GWAS Complexity.

Cell cycle (Georgetown, Tex.)
2016-01 | Journal article
DOI: 10.1080/15384101.2015.1120928
PMID: 26771711
PMC: PMC4825730
Contributors: Hazelett DJ; Conti DV; Han Y; Al Olama AA; Easton D; Eeles RA; Kote-Jarai Z; Haiman CA; Coetzee GA
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

The PsychENCODE project.

Nature neuroscience
2015-12 | Journal article
DOI: 10.1038/nn.4156
PMID: 26605881
PMC: PMC4675669
Contributors: PsychENCODE Consortium; Akbarian S; Liu C; Knowles JA; Vaccarino FM; Farnham PJ; Crawford GE; Jaffe AE; Pinto D; Dracheva S et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Corrigendum: genome-wide association study of colorectal cancer identifies six new susceptibility loci.

Nature communications
2015-10 | Journal article
DOI: 10.1038/ncomms9739
PMID: 26498495
Contributors: Schumacher FR; Schmit SL; Jiao S; Edlund CK; Wang H; Zhang B; Hsu L; Huang SC; Fischer CP; Harju JF et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer.

Carcinogenesis
2015-09 | Journal article
DOI: 10.1093/carcin/bgv138
PMID: 26424751
PMC: PMC4635670
Contributors: Lawrenson K; Iversen ES; Tyrer J; Weber RP; Concannon P; Hazelett DJ; Li Q; Marks JR; Berchuck A; Lee JM et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

motifbreakR: an R/Bioconductor package for predicting variant effects at transcription factor binding sites.

Bioinformatics (Oxford, England)
2015-08 | Journal article
DOI: 10.1093/bioinformatics/btv470
PMID: 26272984
PMC: PMC4653394
Contributors: Coetzee SG; Coetzee GA; Hazelett DJ
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Genome-wide association study of colorectal cancer identifies six new susceptibility loci.

Nature communications
2015-07 | Journal article
DOI: 10.1038/ncomms8138
PMID: 26151821
PMC: PMC4967357
Contributors: Schumacher FR; Schmit SL; Jiao S; Edlund CK; Wang H; Zhang B; Hsu L; Huang SC; Fischer CP; Harju JF et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions.

Human molecular genetics
2015-07 | Journal article
DOI: 10.1093/hmg/ddv269
PMID: 26162851
PMC: PMC4572069
Contributors: Han Y; Hazelett DJ; Wiklund F; Schumacher FR; Stram DO; Berndt SI; Wang Z; Rand KA; Hoover RN; Machiela MJ et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans.

Human molecular genetics
2015-05 | Journal article
DOI: 10.1093/hmg/ddv203
PMID: 26025378
PMC: PMC4572072
Contributors: Amin Al Olama A; Dadaev T; Hazelett DJ; Li Q; Leongamornlert D; Saunders EJ; Stephens S; Cieza-Borrella C; Whitmore I; Benlloch Garcia S et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Identification of a Novel Mucin Gene HCG22 Associated With Steroid-Induced Ocular Hypertension.

Investigative ophthalmology & visual science
2015-04 | Journal article
DOI: 10.1167/iovs.14-14803
PMID: 25813999
PMC: PMC4416661
Contributors: Jeong S; Patel N; Edlund CK; Hartiala J; Hazelett DJ; Itakura T; Wu PC; Avery RL; Davis JL; Flynn HW et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Cell-type-specific enrichment of risk-associated regulatory elements at ovarian cancer susceptibility loci.

Human molecular genetics
2015-03 | Journal article
DOI: 10.1093/hmg/ddv101
PMID: 25804953
PMC: PMC4459387
Contributors: Coetzee SG; Shen HC; Hazelett DJ; Lawrenson K; Kuchenbaecker K; Tyrer J; Rhie SK; Levanon K; Karst A; Drapkin R et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Expression and functional role of orphan receptor GPR158 in prostate cancer growth and progression.

PloS one
2015-02 | Journal article
DOI: 10.1371/journal.pone.0117758
PMID: 25693195
PMC: PMC4333349
Contributors: Patel N; Itakura T; Jeong S; Liao CP; Roy-Burman P; Zandi E; Groshen S; Pinski J; Coetzee GA; Gross ME et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Identification of six new susceptibility loci for invasive epithelial ovarian cancer.

Nature genetics
2015-01 | Journal article
DOI: 10.1038/ng.3185
PMID: 25581431
PMC: PMC4445140
Contributors: Kuchenbaecker KB; Ramus SJ; Tyrer J; Lee A; Shen HC; Beesley J; Lawrenson K; McGuffog L; Healey S; Lee JM et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer.

Nature genetics
2014-09 | Journal article
DOI: 10.1038/ng.3094
PMID: 25217961
PMC: PMC4383163
Contributors: Al Olama AA; Kote-Jarai Z; Berndt SI; Conti DV; Schumacher F; Han Y; Benlloch S; Hazelett DJ; Wang Z; Saunders E et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

A meta-analysis of Hodgkin lymphoma reveals 19p13.3 TCF3 as a novel susceptibility locus.

Nature communications
2014-06 | Journal article
DOI: 10.1038/ncomms4856
PMID: 24920014
PMC: PMC4055950
Contributors: Cozen W; Timofeeva MN; Li D; Diepstra A; Hazelett D; Delahaye-Sourdeix M; Edlund CK; Franke L; Rostgaard K; Van Den Berg DJ et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Nucleosome positioning and histone modifications define relationships between regulatory elements and nearby gene expression in breast epithelial cells.

BMC genomics
2014-05 | Journal article
DOI: 10.1186/1471-2164-15-331
PMID: 24885402
PMC: PMC4035062
Contributors: Rhie SK; Hazelett DJ; Coetzee SG; Yan C; Noushmehr H; Coetzee GA
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Comprehensive functional annotation of 77 prostate cancer risk loci.

PLoS genetics
2014-01 | Journal article
DOI: 10.1371/journal.pgen.1004102
PMID: 24497837
PMC: PMC3907334
Contributors: Hazelett DJ; Rhie SK; Gaddis M; Yan C; Lakeland DL; Coetzee SG; Ellipse/GAME-ON consortium; Practical consortium; Henderson BE; Noushmehr H et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Identification and characterization of functional risk variants for colorectal cancer mapping to chromosome 11q23.1.

Human molecular genetics
2013-11 | Journal article
DOI: 10.1093/hmg/ddt584
PMID: 24256810
PMC: PMC3959808
Contributors: Biancolella M; Fortini BK; Tring S; Plummer SJ; Mendoza-Fandino GA; Hartiala J; Hitchler MJ; Yan C; Schumacher FR; Conti DV et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Knockdown of the cochaperone SGTA results in the suppression of androgen and PI3K/Akt signaling and inhibition of prostate cancer cell proliferation.

International journal of cancer
2013-07 | Journal article
DOI: 10.1002/ijc.28310
PMID: 23740762
Contributors: Trotta AP; Need EF; Selth LA; Chopra S; Pinnock CB; Leach DA; Coetzee GA; Butler LM; Tilley WD; Buchanan G
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Biological implications and regulatory mechanisms of long-range chromosomal interactions.

The Journal of biological chemistry
2013-06 | Journal article
DOI: 10.1074/jbc.r113.485292
PMID: 23779110
PMC: PMC3829327
Contributors: Wei Z; Huang D; Gao F; Chang WH; An W; Coetzee GA; Wang K; Lu W
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Comprehensive functional annotation of seventy-one breast cancer risk Loci.

PloS one
2013-05 | Journal article
DOI: 10.1371/journal.pone.0063925
PMID: 23717510
PMC: PMC3661550
Contributors: Rhie SK; Coetzee SG; Noushmehr H; Yan C; Kim JM; Haiman CA; Coetzee GA
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.

Nature genetics
2013-04 | Journal article
DOI: 10.1038/ng.2608
PMID: 23583978
PMC: PMC3694490
Contributors: Monda KL; Chen GK; Taylor KC; Palmer C; Edwards TL; Lange LA; Ng MC; Adeyemo AA; Allison MA; Bielak LF et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Genome-wide association studies identify four ER negative-specific breast cancer risk loci.

Nature genetics
2013-04 | Journal article
DOI: 10.1038/ng.2561
PMID: 23535733
PMC: PMC3771695
Contributors: Garcia-Closas M; Couch FJ; Lindstrom S; Michailidou K; Schmidt MK; Brook MN; Orr N; Rhie SK; Riboli E; Feigelson HS et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.

Nature genetics
2013-04 | Journal article
DOI: 10.1038/ng.2564
PMID: 23535730
PMC: PMC3693183
Contributors: Pharoah PD; Tsai YY; Ramus SJ; Phelan CM; Goode EL; Lawrenson K; Buckley M; Fridley BL; Tyrer JP; Shen H et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.

Nature communications
2013-01 | Journal article
DOI: 10.1038/ncomms2613
PMID: 23535648
PMC: PMC3709460
Contributors: Permuth-Wey J; Lawrenson K; Shen HC; Velkova A; Tyrer JP; Chen Z; Lin HY; Chen YA; Tsai YY; Qu X et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer.

Nature genetics
2012-12 | Journal article
DOI: 10.1038/ng.2505
PMID: 23263487
PMC: PMC3679924
Contributors: Jia WH; Zhang B; Matsuo K; Shin A; Xiang YB; Jee SH; Kim DH; Ren Z; Cai Q; Long J et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.

Gastroenterology
2012-12 | Journal article
DOI: 10.1053/j.gastro.2012.12.020
PMID: 23266556
PMC: PMC3636812
Contributors: Peters U; Jiao S; Schumacher FR; Hutter CM; Aragaki AK; Baron JA; Berndt SI; Bézieau S; Brenner H; Butterbach K et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity.

Genome biology
2012-10 | Journal article
DOI: 10.1186/gb-2012-13-10-r88
PMID: 23034120
PMC: PMC3491416
Contributors: Tewari AK; Yardimci GG; Shibata Y; Sheffield NC; Song L; Taylor BS; Georgiev SG; Coetzee GA; Ohler U; Furey TS et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11.

Human molecular genetics
2012-09 | Journal article
DOI: 10.1093/hmg/dds381
PMID: 22976474
PMC: PMC3510753
Contributors: Siddiq A; Couch FJ; Chen GK; Lindström S; Eccles D; Millikan RC; Michailidou K; Stram DO; Beckmann L; Rhie SK et al.
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Subdomain structure of the co-chaperone SGTA and activity of its androgen receptor client.

Journal of molecular endocrinology
2012-07 | Journal article
DOI: 10.1530/jme-11-0152
PMID: 22693264
Contributors: Trotta AP; Need EF; Butler LM; Selth LA; O'Loughlin MA; Coetzee GA; Tilley WD; Buchanan G
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

FunciSNP: an R/bioconductor tool integrating functional non-coding data sets with genetic association studies to identify candidate regulatory SNPs.

Nucleic acids research
2012-06 | Journal article
DOI: 10.1093/nar/gks542
PMID: 22684628
PMC: PMC3467035
Contributors: Coetzee SG; Rhie SK; Berman BP; Coetzee GA; Noushmehr H
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

A noncoding RNA antisense to moesin at 5p14.1 in autism.

Science translational medicine
2012-04 | Journal article
DOI: 10.1126/scitranslmed.3003479
PMID: 22491950
Contributors: Kerin T; Ramanathan A; Rivas K; Grepo N; Coetzee GA; Campbell DB
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

A rare variant, which destroys a FoxA1 site at 8q24, is associated with prostate cancer risk.

Cell cycle (Georgetown, Tex.)
2012-01 | Journal article
DOI: 10.4161/cc.23201
PMID: 23255135
PMC: PMC3575466
Contributors: Hazelett DJ; Coetzee SG; Coetzee GA
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

An enhancer from the 8q24 prostate cancer risk region is sufficient to direct reporter gene expression to a subset of prostate stem-like epithelial cells in transgenic mice.

Disease models & mechanisms
2012-01 | Journal article
DOI: 10.1242/dmm.008458
PMID: 22279083
PMC: PMC3339830
Contributors: Ting MC; Liao CP; Yan C; Jia L; Groshen S; Frenkel B; Roy-Burman P; Coetzee GA; Maxson R
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Genome-wide Runx2 occupancy in prostate cancer cells suggests a role in regulating secretion.

Nucleic acids research
2011-12 | Journal article
DOI: 10.1093/nar/gkr1219
PMID: 22187159
PMC: PMC3333873
Contributors: Little GH; Noushmehr H; Baniwal SK; Berman BP; Coetzee GA; Frenkel B
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central

Identification and functional annotation of GWAS risk SNPs.

Cell cycle (Georgetown, Tex.)
2011-12 | Journal article
DOI: 10.4161/cc.10.23.18237
PMID: 22101276
Contributors: Noushmehr H; Coetzee GA
Source: Self-asserted source
Gerhard Coetzee via Europe PubMed Central
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