Personal information

Other IDs

ResearcherID: F-8513-2011

Keywords

Telomere, Replicative senescence, Microfluidics, Adaptation

Countries

France

Activities

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Employment (7)

CNRS Délégation Paris B: Paris, Île-de-France, FR

2022-10-01 to present | Research Director
Employment
Source: Self-asserted source
Zhou Xu

CNRS and Sorbonne University: Paris, FR

2018-12-01 to present | Group Leader
Employment
Source: Self-asserted source
Zhou Xu

Mines Paris - PSL: Paris, Île-de-France, FR

2017-04-01 to 2022-09-30 | Assistant Professor (Biotechnologies)
Employment
Source: Self-asserted source
Zhou Xu

CNRS Délégation Paris B: Paris, Île-de-France, FR

2016-10-01 to 2022-09-30 | Researcher
Employment
Source: Self-asserted source
Zhou Xu

Université Pierre et Marie Curie: Paris, Île-de-France, FR

2011-10-10 to 2016-09-31 | Postdoc (UMR8226)
Employment
Source: Self-asserted source
Zhou Xu

CNRS: Paris, Île-de-France, FR

2011-10-10 to 2016-09-31 | Postdoc (UMR8226)
Employment
Source: Self-asserted source
Zhou Xu

CEA Fontenay-aux-Roses: Fontenay-aux-Roses, Île-de-France, FR

2008-10-01 to 2011-09-31 | PhD student (IMETI/SEPIA)
Employment
Source: Self-asserted source
Zhou Xu

Education and qualifications (4)

Sorbonne Université: Paris, Île-de-France, FR

2019-12-16 to 2019-12-16 | Habilitation à diriger des recherches
Qualification
Source: Self-asserted source
Zhou Xu

Université Paris Diderot: Paris, FR

2008-10-01 to 2011-09-30 | PhD
Education
Source: Self-asserted source
Zhou Xu

Mines ParisTech: Paris, Île-de-France, FR

2007-09-01 to 2008-09-31 | Master/Engineer
Education
Source: Self-asserted source
Zhou Xu

École Polytechnique: Palaiseau, FR

2004-09-01 to 2008-09-31 | Master/Engineer
Education
Source: Self-asserted source
Zhou Xu

Works (27)

The CST complex mediates a post-resection non-homologous end-joining repair pathway and promotes local deletions

2025-02-07 | Preprint
DOI: 10.1101/2025.02.07.637039
Contributors: Oana Ilioaia; Liébaut Dudragne; Clémentine Brocas; Léa Meneu; Romain Koszul; Karine Dubrana; Zhou Xu
Source: check_circle
Crossref

Mathematical model linking telomeres to senescence in Saccharomyces cerevisiae reveals cell lineage versus population dynamics

Nature Communications
2025-01-25 | Journal article
DOI: 10.1038/s41467-025-56196-z
Contributors: Anaïs Rat; Veronica Martinez Fernandez; Marie Doumic; Maria Teresa Teixeira; Zhou Xu
Source: check_circle
Crossref

Extraction and selection of high-molecular-weight DNA for long-read sequencing from Chlamydomonas reinhardtii

PLOS ONE
2024-02-08 | Journal article
DOI: 10.1371/journal.pone.0297014
Contributors: Frédéric Chaux; Ramachandran Srinivasan; Nicolas Agier; Stephan Eberhard; Zhou Xu
Source: check_circle
Crossref

Individual cell fate and population dynamics revealed by a mathematical model linking telomere length and replicative senescence

2023-11-22 | Preprint
DOI: 10.1101/2023.11.22.568287
Contributors: Anaïs Rat; Marie Doumic; Maria Teresa Teixeira; Zhou Xu
Source: check_circle
Crossref

Telomerase-independent survival leads to a mosaic of complex subtelomere rearrangements inChlamydomonas reinhardtii

Genome Research
2023-09 | Journal article
DOI: 10.1101/gr.278043.123
Contributors: Frédéric Chaux; Nicolas Agier; Clotilde Garrido; Gilles Fischer; Stephan Eberhard; Zhou Xu
Source: check_circle
Crossref

Telomerase-independent survival leads to a mosaic of complex subtelomere rearrangements inChlamydomonas reinhardtii

2023-01-23 | Preprint
DOI: 10.1101/2023.01.23.525193
Contributors: Frédéric Chaux; Nicolas Agier; Clotilde Garrido; Gilles Fischer; Stephan Eberhard; Zhou Xu
Source: check_circle
Crossref

The Polo kinase Cdc5 is regulated at multiple levels in the adaptation response to telomere dysfunction

Genetics
2023-01-12 | Journal article
DOI: 10.1093/genetics/iyac171
Contributors: Héloïse Coutelier; Oana Ilioaia; Jeanne Le Peillet; Marion Hamon; Damien D’Amours; Maria Teresa Teixeira; Zhou Xu; A MacQueen
Source: check_circle
Crossref

La révolution de l’ADN: biocompatible and biosafe DNA data storage

2022-08-25 | Preprint
DOI: 10.1101/2022.08.25.505104
Contributors: Alexandre Maes; Jeanne Le Peillet; Achille Julienne; Clémence Blachon; Nicolas Cornille; Mariette Gibier; Erfane Arwani; Zhou Xu; Pierre Crozet; Stéphane D. Lemaire
Source: check_circle
Crossref

Extraction and selection of high-molecular-weight DNA for long-read sequencing from Chlamydomonas reinhardtii

2022-08-16 | Preprint
DOI: 10.1101/2022.08.16.504088
Contributors: Frédéric Chaux-Jukic; Nicolas Agier; Stephan Eberhard; Zhou Xu
Source: check_circle
Crossref

Telomere shortening causes distinct cell division regimes during replicative senescence in Saccharomyces cerevisiae

Cell & Bioscience
2021-12 | Journal article
DOI: 10.1186/s13578-021-00693-3
DOI: 10.1101/2021.06.16.448683
Contributors: Hugo Martin; Marie Doumic; Maria Teresa Teixeira; Zhou Xu
Source: Self-asserted source
Zhou Xu
grade
Preferred source (of 3)‎

The Polo kinase Cdc5 is regulated at multiple levels in the adaptation response to telomere dysfunction

2021-10-20 | Other
DOI: 10.1101/2021.10.20.465143
Contributors: Héloïse Coutelier; Oana Ilioaia; Jeanne Le Peillet; Marion Hamon; Damien D’Amours; Maria Teresa Teixeira; Zhou Xu
Source: check_circle
Crossref

Adaptation to DNA damage as a bet-hedging mechanism in a fluctuating environment

Royal Society Open Science
2021-08 | Journal article
DOI: 10.1098/rsos.210460
DOI: 10.1101/2021.03.02.433602
Contributors: Pierre Roux; Delphine Salort; Zhou Xu
Source: Self-asserted source
Zhou Xu
grade
Preferred source (of 3)‎

Architecture and evolution of subtelomeres in the unicellular green alga Chlamydomonas reinhardtii

Nucleic Acids Research
2021-07-21 | Journal article
DOI: 10.1093/nar/gkab534
DOI: 10.1101/2021.01.29.428817
Contributors: Frédéric Chaux-Jukic; Samuel O’Donnell; Rory J Craig; Stephan Eberhard; Olivier Vallon; Zhou Xu
Source: Self-asserted source
Zhou Xu
grade
Preferred source (of 3)‎

WITHDRAWN: Rad5 and Rad51 act at telomeres through two partially distinct pathways

2020-08-31 | Preprint
DOI: 10.1101/2020.08.27.269621
Contributors: Erin E. Henninger; Pascale Jolivet; Prisca Berardi; Emilie Fallet; Mohcen Benmounah; Bechara Zeinoun; Gilles Charvin; Zhou Xu; Stefano Mattarocci; Maria Teresa Teixeira
Source: check_circle
Crossref

The many types of heterogeneity in replicative senescence

Yeast
2019-11 | Journal article
DOI: 10.1002/yea.3433
Contributors: Zhou Xu; Maria Teresa Teixeira
Source: check_circle
Crossref

Adaptation in replicative senescence: a risky business

Current Genetics
2019-06-12 | Journal article
DOI: 10.1007/s00294-019-00933-7
Contributors: Héloïse Coutelier; Zhou Xu
Source: check_circle
Crossref

Molecular characterization of Chlamydomonas reinhardtii telomeres and telomerase mutants

Life Science Alliance
2019-06-03 | Journal article
DOI: 10.26508/lsa.201900315
DOI: 10.1101/519991
Part of ISSN: 2575-1077
Source: Self-asserted source
Zhou Xu
grade
Preferred source (of 3)‎

A subtelomeric region affects telomerase-negative replicative senescence in Saccharomyces cerevisiae

Scientific Reports
2019-02-12 | Journal article
DOI: 10.1038/s41598-018-38000-9
Contributors: Pascale Jolivet; Kamar Serhal; Marco Graf; Stephan Eberhard; Zhou Xu; Brian Luke; Maria Teresa Teixeira
Source: check_circle
Crossref

Adaptation to DNA damage checkpoint in senescent telomerase-negative cells promotes genome instability

Genes & Development
2018-12-01 | Journal article
DOI: 10.1101/gad.318485.118
Contributors: Héloïse Coutelier; Zhou Xu; Mony Chenda Morisse; Maoussi Lhuillier-Akakpo; Serge Pelet; Gilles Charvin; Karine Dubrana; Maria Teresa Teixeira
Source: check_circle
Crossref

Effects of initial telomere length distribution on senescence onset and heterogeneity

Journal of Theoretical Biology
2017-01 | Journal article
DOI: 10.1016/j.jtbi.2016.11.010
Contributors: Sarah Eugène; Thibault Bourgeron; Zhou Xu
Source: Self-asserted source
Zhou Xu via Crossref Metadata Search
grade
Preferred source (of 2)‎

The asymmetry of telomere replication contributes to replicative senescence heterogeneity

Sci. Rep.
2015-10 | Journal article
DOI: 10.1038/srep15326
Contributors: Thibault Bourgeron; Zhou Xu; Marie Doumic; Maria Teresa Teixeira
Source: Self-asserted source
Zhou Xu via Crossref Metadata Search

Two routes to senescence revealed by real-time analysis of telomerase-negative single lineages

Nat Comms
2015-07-09 | Journal article
DOI: 10.1038/ncomms8680
Contributors: Zhou Xu; Emilie Fallet; Camille Paoletti; Steffen Fehrmann; Gilles Charvin; Maria Teresa Teixeira
Source: Self-asserted source
Zhou Xu via Crossref Metadata Search

The prion protein is critical for DNA repair and cell survival after genotoxic stress

Nucleic Acids Research
2014 | Journal article
DOI: 10.1093/nar/gku1342
Contributors: A. Bravard; F. Auvre; D. Fantini; J. Bernardino-Sgherri; L. Sissoeff; M. Daynac; Z. Xu; O. Etienne; C. Dehen; E. Comoy et al.
Source: Self-asserted source
Zhou Xu via Crossref Metadata Search

The Length of the Shortest Telomere as the Major Determinant of the Onset of Replicative Senescence

Genetics
2013-06-03 | Journal article
DOI: 10.1534/genetics.113.152322
Contributors: Z. Xu; K. D. Duc; D. Holcman; M. T. Teixeira
Source: Self-asserted source
Zhou Xu via Crossref Metadata Search

Dual Conformation of H2H3 Domain of Prion Protein in Mammalian Cells

Journal of Biological Chemistry
2011-09 | Journal article
DOI: 10.1074/jbc.m111.275255
Contributors: Z. Xu; S. Prigent; J.-P. Deslys; H. Rezaei
Source: Self-asserted source
Zhou Xu via Crossref Metadata Search

Mechanistic insights into cellular alteration of prion by poly-D-lysine: the role of H2H3 domain

The FASEB Journal
2011-06 | Journal article
DOI: 10.1096/fj.11-187534
Contributors: Z. Xu; M. Adrover; A. Pastore; S. Prigent; F. Mouthon; E. Comoy; H. Rezaei; J.-P. Deslys
Source: Self-asserted source
Zhou Xu via Crossref Metadata Search

Prion Fibrillization Is Mediated by a Native Structural Element That Comprises Helices H2 and H3

J. Biol. Chem.
2010-04-07 | Journal article
DOI: 10.1074/jbc.m110.111815
Contributors: Miquel Adrover; Kris Pauwels; Stephanie Prigent; Cesira de Chiara; Zhou Xu; Céline Chapuis; Annalisa Pastore; Human Rezaei
Source: Self-asserted source
Zhou Xu via Crossref Metadata Search

Peer review (4 reviews for 3 publications/grants)

Review activity for eLife (2)
Review activity for Nature communications (1)
Review activity for PLOS genetics. (1)
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