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Universidad de la República Facultad de Ciencias: Montevideo, Montevideo, UY

2020-05-01 to present | Assistant (Grado 2) (Sección Bioquímica)
Employment
Source: Self-asserted source
Ignacio López

Works (17)

Re-appraising the evidence for the source, regulation and function of p53-family isoforms

Nucleic Acids Research
2024-11-11 | Journal article
DOI: 10.1093/nar/gkae855
Contributors: Ignacio López; Irene Larghero Valdivia; Borivoj Vojtesek; Robin Fåhraeus; Philip J Coates
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Crossref

The p53 endoplasmic reticulum stress-response pathway evolved in humans but not in mice via PERK-regulated p53 mRNA structures

Cell Death & Differentiation
2023-04 | Journal article
DOI: 10.1038/s41418-023-01127-y
Contributors: Leila Fusée; Norman Salomao; Anand Ponnuswamy; Lixiao Wang; Ignacio López; Sa Chen; Xiaolian Gu; Stavros Polyzoidis; Sivakumar Vadivel Gnanasundram; Robin Fahraeus
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Crossref

Ready to migrate? Reading cellular signs of migration in an epithelial to mesenchymal transition model

BIOCELL
2022 | Journal article
DOI: 10.32604/biocell.2022.020966
Part of ISSN: 1667-5746
Contributors: Tamara Fernández-Calero; Ignacio López; Marcos Davyt; Cora Chalar; Ricardo Ehrlich; Mónica Marín
Source: Self-asserted source
Ignacio López

On the Track of the Missing tRNA Genes: A Source of Non-Canonical Functions?

Frontiers in molecular biosciences
2021-03-16 | Journal article
DOI: 10.3389/fmolb.2021.643701
PMID: 33796548
PMC: PMC8007984
Source: Self-asserted source
Ignacio López

Global DNA hypermethylation pattern and unique gene expression signature in liver cancer from patients with Indigenous American ancestry.

Oncotarget
2021-03-02 | Journal article
DOI: 10.18632/oncotarget.27890
PMID: 33747361
PMC: PMC7939527
Source: Self-asserted source
Ignacio López

Molecular and Biochemical Techniques for Deciphering p53-MDM2 Regulatory Mechanisms

Biomolecules
2020-12-30 | Journal article
DOI: 10.3390/biom11010036
Contributors: Konstantinos Karakostis; Ignacio López; Ana M. Peña-Balderas; Robin Fåhareus; Vanesa Olivares-Illana
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Crossref
grade
Preferred source (of 2)‎

An unanticipated tumor-suppressive role of the SUMO pathway in the intestine unveiled by Ubc9 haploinsufficiency

Oncogene
2020-10-22 | Journal article
DOI: 10.1038/s41388-020-01457-y
Contributors: Ignacio López; Eleftheria Chalatsi; Saskia I. J. Ellenbroek; Alexandra Andrieux; Pierre-François Roux; Juan P. Cerapio; Grégory Jouvion; Jacco van Rheenen; Jacob-S. Seeler; Anne Dejean
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Crossref

Expression, purification and initial characterization of human serum albumin domain I and its cysteine 34

PLOS ONE
2020-10-12 | Journal article
DOI: 10.1371/journal.pone.0240580
Contributors: Martina Steglich; Eugene A. Permyakov; Rodrigo Lombide; Ignacio López; Madelón Portela; Martín Fló; Mónica Marín; Beatriz Alvarez; Lucía Turell
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Crossref

Alternative Mechanisms of p53 Action During the Unfolded Protein Response

Cancers
2020-02-10 | Journal article
DOI: 10.3390/cancers12020401
Contributors: Leïla T. S. Fusée; Mónica Marín; Robin Fåhraeus; Ignacio López
Source: check_circle
Crossref

A single synonymous mutation determines the phosphorylation and stability of the nascent protein

Journal of Molecular Cell Biology
2019-03-01 | Journal article
DOI: 10.1093/jmcb/mjy049
Contributors: Konstantinos Karakostis; Sivakumar Vadivel Gnanasundram; Ignacio López; Aikaterini Thermou; Lixiao Wang; Karin Nylander; Vanesa Olivares-Illana; Robin Fåhraeus; Chandra S Verma
Source: check_circle
Crossref

p53-mediated suppression of BiP triggers BIK-induced apoptosis during prolonged endoplasmic reticulum stress.

Cell Death and Differentiation
2017-10 | Journal article
DOI: 10.1038/cdd.2017.96
PMID: 28622297
PMC: PMC5596431
Source: Self-asserted source
Ignacio López via Europe PubMed Central

p53 binds the mdmx mRNA and controls its translation.

2017-02 | Journal article
DOI: 10.1038/onc.2016.236
PMID: 27375027
Source: Self-asserted source
Ignacio López
grade
Preferred source (of 2)‎

p53-mediated control of gene expression via mRNA translation during Endoplasmic Reticulum stress.

2015 | Journal article
DOI: 10.1080/15384101.2015.1090066
PMID: 26397130
PMC: PMC4825612
Contributors: López I; Tournillon AS; Nylander K; Fåhraeus R
Source: Self-asserted source
Ignacio López via Europe PubMed Central

The alternative translated MDMX(p60) isoform regulates MDM2 activity.

2015 | Journal article
DOI: 10.4161/15384101.2014.977081
PMID: 25659040
PMC: PMC4615104
Contributors: Tournillon AS; López I; Malbert-Colas L; Naski N; Olivares-Illana V; Fåhraeus R
Source: Self-asserted source
Ignacio López via Europe PubMed Central

Association of the p53 codon 72 polymorphism with clinicopathological characteristics of colorectal cancer through mRNA analysis.

2014-03 | Journal article
DOI: 10.3892/or.2013.2940
PMID: 24366026
Contributors: De Oliveira LP; López I; Dos Santos EM; Tucci P; Marín M; Soares FA; Rossi BM; Coudry Rde A
Source: Self-asserted source
Ignacio López via Europe PubMed Central

Different mutation profiles associated to P53 accumulation in colorectal cancer.

2012-05 | Journal article
DOI: 10.1016/j.gene.2012.02.011
PMID: 22373952
Contributors: López I; P Oliveira L; Tucci P; Alvarez-Valín F; A Coudry R; Marín M
Source: Self-asserted source
Ignacio López via Europe PubMed Central

First detection of canine parvovirus type 2c in South America.

2007-09 | Journal article
DOI: 10.1016/j.vetmic.2007.04.028
PMID: 17531408
Contributors: Pérez R; Francia L; Romero V; Maya L; López I; Hernández M
Source: Self-asserted source
Ignacio López via Europe PubMed Central
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