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ResearcherID: I-2838-2015
Scopus Author ID: 6701694858
SciProfiles: 686072

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Employment (1)

Universidad de Alcalá de Henares Facultad de Medicina y Ciencias de la Salud: Alcala de Henares, Madrid, ES

2009-10-15 to present | Catedrático de Universidad (Systems Biology)
Employment
Source: Self-asserted source
Ines Diaz-Laviada

Education and qualifications (1)

Universidad Complutense de Madrid: Madrid, Comunidad de Madrid, ES

1985-06 to 1989-06-30 | PhD Biology (Biochemistry and Molecular Biology)
Education
Source: Self-asserted source
Ines Diaz-Laviada

Funding (2)

Covid-19 y Diabetes. Estudio integrado del papel de la Dipeptidil peptidasa 4 en la infección por SARSCoV- 2.

2020-01 to 2022-12 | Grant
Comunidad de Madrid (Madrid, ES)
Source: Self-asserted source
Ines Diaz-Laviada

Estudio de la actividad antitumoral de diferentes fitoquímicos en el cáncer de próstata y el cáncer hepatocelular. Papel del metabolismo celular

2013-06 to 2018-06 | Grant
Fundación Tatiana Pérez de Guzmán el Bueno (Madrid, madrid, ES)
GRANT_NUMBER:

Patrocinio 2013-01
Source: Self-asserted source
Ines Diaz-Laviada

Works (50 of 133)

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Diabetic individuals with COVID-19 exhibit reduced efficacy of gliptins in inhibiting dipeptidyl peptidase 4 (DPP4). A suggested explanation for increased COVID-19 susceptibility in patients with type 2 diabetes mellitus (T2DM)

Life Sciences
2024-01 | Journal article
DOI: 10.1016/j.lfs.2023.122292
Part of ISSN: 0024-3205
Contributors: José María Mora-Rodríguez; Belén G. Sánchez; Alicia Bort; Alba Díaz-Yuste; Rubén Ballester-González; Francisco Arrieta; Alba Sebastián-Martín; Inés Díaz-Laviada
Source: Self-asserted source
Ines Diaz-Laviada

Resistance to 2-Hydroxy-Flutamide in Prostate Cancer Cells Is Associated with the Downregulation of Phosphatidylcholine Biosynthesis and Epigenetic Modifications

International Journal of Molecular Sciences
2023-10-26 | Journal article
DOI: 10.3390/ijms242115626
Contributors: José María Mora-Rodríguez; Belén G. Sánchez; Alba Sebastián-Martín; Alba Díaz-Yuste; Manuel Sánchez-Chapado; Ana María Palacín; Carlos Sánchez-Rodríguez; Alicia Bort; Inés Díaz-Laviada
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Alteration of the HIF-1α/VEGF Signaling Pathway and Disruption of the Cell Cycle by Second Generation Carbosilan Dendrimers

Biomacromolecules
2022-12-12 | Journal article
DOI: 10.1021/acs.biomac.2c00899
Contributors: Oscar Barrios; Belén G. Sánchez; Tamara Rodríguez-Prieto; Jesús Cano; Alicia Bort; Rafael Gómez; Inés Díaz-Laviada
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A Highly Sensitive Immunoassay for Determination of Immune Response to SARS-CoV-2 in Capillary Blood Samples

Biomedicines
2022-11-11 | Journal article
DOI: 10.3390/biomedicines10112897
Contributors: Belén G. Sánchez; Alicia Bort; José María Mora-Rodríguez; Alba Díaz-Yuste; José Manuel Gasalla; Manuel Sánchez-Chapado; Alba Sebastián-Martín; Inés Díaz-Laviada
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Role of Dipeptidyl Peptidase-4 (DPP4) on COVID-19 Physiopathology

Biomedicines
2022-08-19 | Journal article
DOI: 10.3390/biomedicines10082026
Contributors: Alba Sebastián-Martín; Belén G. Sánchez; José M. Mora-Rodríguez; Alicia Bort; Inés Díaz-Laviada
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THE DEBATE AS A TOOL FOR SCIENCE LEARNING AND EVALUATION OF SCIENTIFIC WORK. APPLICATION TO POSTGRADUATE TEACHING IN BIOMEDICINE

2022-07 | Conference paper
DOI: 10.21125/edulearn.2022.0300
Contributors: Alicia Bort; Belen Sánchez; Jose M. Mora-Rodríguez; Inés Díaz-Laviada
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The Natural Chemotherapeutic Capsaicin Activates AMPK through LKB1 Kinase and TRPV1 Receptors in Prostate Cancer Cells

Pharmaceutics
2022-01-29 | Journal article
DOI: 10.3390/pharmaceutics14020329
Contributors: Belén G. Sánchez; Alicia Bort; José M. Mora-Rodríguez; Inés Díaz-Laviada
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)<sup>1</sup>

Autophagy
2021 | Journal article
DOI: 10.1080/15548627.2020.1797280
EID:

2-s2.0-85102619204

Part of ISSN: 15548635 15548627
Contributors: Klionsky, D.J.; Abdel-Aziz, A.K.; Abdelfatah, S.; Abdellatif, M.; Abdoli, A.; Abel, S.; Abeliovich, H.; Abildgaard, M.H.; Abudu, Y.P.; Acevedo-Arozena, A. et al.
Source: Self-asserted source
Ines Diaz-Laviada via Scopus - Elsevier

Increase in Ischemia-Modified Albumin and Pregnancy-Associated Plasma Protein-A in COVID-19 Patients

Journal of Clinical Medicine
2021-11 | Journal article | Author
DOI: 10.3390/jcm10235474
Contributors: Belén G. Sanchez; Jose M. Gasalla; Manuel Sánchez-Chapado; Alicia Bort; Ines Diaz-Laviada
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Multidisciplinary Digital Publishing Institute
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Potential Use of Pregnancy-associated Plasma Protein-A and IMA as Biomarkers for the Early Stage of COVID-19

2021-08-06 | Other
DOI: 10.21203/rs.3.rs-769766/v1
Contributors: Belén G Sánchez; Jose M Gasalla; Manuel Sanchez-Chapado; Alicia Bort; Ines Diaz-Laviada
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DESIGN AND DEVELOPMENT OF VIRTUAL LEARNING TOOLS TO BE USED IN BIOMEDICAL PRACTICAL TEACHING

2021-07 | Conference paper
DOI: 10.21125/edulearn.2021.2375
Contributors: Alicia Bort; Belen Sanchez; Ines Diaz-Laviada
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Androgen Deprivation Induces Reprogramming of Prostate Cancer Cells to Stem-Like Cells

Cells
2020-06-10 | Journal article
DOI: 10.3390/cells9061441
Contributors: Belén G. Sánchez; Alicia Bort; Diana Vara-Ciruelos; Inés Díaz-Laviada
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Dysregulated lipid metabolism in hepatocellular carcinoma cancer stem cells

Molecular Biology Reports
2020-04-03 | Journal article
DOI: 10.1007/s11033-020-05352-3
Contributors: Alicia Bort; Belén G. Sánchez; Irene de Miguel; Pedro A. Mateos-Gómez; Inés Diaz-Laviada
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Capsaicin targets lipogenesis in hepG2 cells through AMPK activation, AKT inhibition and ppars regulation

International Journal of Molecular Sciences
2019 | Journal article
DOI: 10.3390/ijms20071660
EID:

2-s2.0-85064953561

Part of ISSN: 14220067 16616596
Contributors: Bort, A.; Sánchez, B.G.; Mateos-Gómez, P.A.; Díaz-Laviada, I.; Rodríguez-Henche, N.
Source: Self-asserted source
Ines Diaz-Laviada via Scopus - Elsevier

Targeting AMP-activated kinase impacts hepatocellular cancer stem cells induced by long-term treatment with sorafenib

Molecular Oncology
2019 | Journal article
DOI: 10.1002/1878-0261.12488
EID:

2-s2.0-85065041330

Part of ISSN: 18780261 15747891
Contributors: Bort, A.; Sánchez, B.G.; Mateos-Gómez, P.A.; Vara-Ciruelos, D.; Rodríguez-Henche, N.; Díaz-Laviada, I.
Source: Self-asserted source
Ines Diaz-Laviada via Scopus - Elsevier

Combination of the natural product capsaicin and docetaxel synergistically kills human prostate cancer cells through the metabolic regulator AMP-activated kinase

Cancer Cell International
2019-12 | Journal article
DOI: 10.1186/s12935-019-0769-2
Contributors: Belén G. Sánchez; Alicia Bort; Pedro A. Mateos-Gómez; Nieves Rodríguez-Henche; Inés Díaz-Laviada
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The red pepper's spicy ingredient capsaicin activates AMPK in HepG2 cells through CaMKKβ.

PloS one
2019-01 | Journal article
DOI: 10.1371/journal.pone.0211420
PMID: 30695053
Contributors: Bort A; Sánchez BG; Spínola E; Mateos-Gómez PA; Rodríguez-Henche N; Díaz-Laviada I
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Ines Diaz-Laviada via Europe PubMed Central
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Selbstanordnung von BODIPY‐Farbstoffen als Werkzeug, um die Antitumoraktivität von Capsaicin bei Prostatakrebs zu erhöhen

Angewandte Chemie
2018-12-21 | Journal article
DOI: 10.1002/ange.201804783
Contributors: Angel Sampedro; Ágata Ramos‐Torres; Christian Schwöppe; Christian Mück‐Lichtenfeld; Ingo Helmers; Alicia Bort; Inés Díaz‐Laviada; Gustavo Fernández
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Hierarchical Self-Assembly of BODIPY Dyes as a Tool to Improve the Antitumor Activity of Capsaicin in Prostate Cancer.

Angewandte Chemie (International ed. in English)
2018-11 | Journal article
DOI: 10.1002/anie.201804783
PMID: 30324638
Contributors: Sampedro A; Ramos-Torres Á; Schwöppe C; Mück-Lichtenfeld C; Helmers I; Bort A; Díaz-Laviada I; Fernández G
Source: Self-asserted source
Ines Diaz-Laviada via Europe PubMed Central
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Identification of a novel 2-oxindole fluorinated derivative as in vivo antitumor agent for prostate cancer acting via AMPK activation.

Scientific reports
2018-03 | Journal article
DOI: 10.1038/s41598-018-22690-2
PMID: 29531259
PMC: PMC5847527
Contributors: Bort A; Quesada S; Ramos-Torres Á; Gargantilla M; Priego EM; Raynal S; Lepifre F; Gasalla JM; Rodriguez-Henche N; Castro A et al.
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Ines Diaz-Laviada via Europe PubMed Central
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Capsaicin exerts synergistic antitumor effect with sorafenib in hepatocellular carcinoma cells through AMPK activation.

Oncotarget
2017-09 | Journal article
DOI: 10.18632/oncotarget.21196
PMID: 29152112
PMC: PMC5675664
Contributors: Bort A; Spínola E; Rodríguez-Henche N; Díaz-Laviada I
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Ines Diaz-Laviada via Europe PubMed Central
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Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Autophagy
2016 | Journal article
DOI: 10.1080/15548627.2016.1147886
EID:

2-s2.0-85054826264

Part of ISSN: 15548635 15548627
Contributors: Klionsky, D.J.; Abdelmohsen, K.; Abe, A.; Abedin, M.J.; Abeliovich, H.; Arozena, A.A.; Adachi, H.; Adams, C.M.; Adams, P.D.; Adeli, K. et al.
Source: Self-asserted source
Ines Diaz-Laviada via Scopus - Elsevier

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Autophagy
2016 | Journal article
DOI: 10.1080/15548627.2015.1100356
WOSUID:

WOS:000373595400001
Contributors: Klionsky, Daniel J.; Abdelmohsen, Kotb; Abe, Akihisa; Abedin, Md Joynal; Abeliovich, Hagai; Arozena, Abraham Acevedo; Adachi, Hiroaki; Adams, Christopher M.; Adams, Peter D.; Adeli, Khosrow et al.
Source: Self-asserted source
Ines Diaz-Laviada via ResearcherID
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The cannabinoid WIN 55,212-2 prevents neuroendocrine differentiation of LNCaP prostate cancer cells

Prostate Cancer and Prostatic Diseases
2016 | Journal article
DOI: 10.1038/pcan.2016.19
WOSUID:

WOS:000381961100004
Contributors: Morell, C.; Bort, A.; Vara, D.; Ramos-Torres, A.; Rodriguez-Henche, N.; Diaz-Laviada, I.
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Ines Diaz-Laviada via ResearcherID
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The pepper's natural ingredient capsaicin induces autophagy blockage in prostate cancer cells

Oncotarget
2016 | Journal article
WOSUID:

WOS:000369951100038
Contributors: Ramos-Torres, Agata; Bort, Alicia; Morell, Cecilia; Rodriguez-Henche, Nieves; Diaz-Laviada, Ines
Source: Self-asserted source
Ines Diaz-Laviada via ResearcherID

Up-Regulated Expression of LAMP2 and Autophagy Activity during Neuroendocrine Differentiation of Prostate Cancer LNCaP Cells

Plos One
2016 | Journal article
DOI: 10.1371/journal.pone.0162977
WOSUID:

WOS:000383680600071
Contributors: Morell, Cecilia; Bort, Alicia; Vara-Ciruelos, Diana; Ramos-Torres, Agata; Altamirano-Dimas, Manuel; Diaz-Laviada, Ines; Rodriguez-Henche, Nieves
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Ines Diaz-Laviada via ResearcherID
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The pepper's natural ingredient capsaicin induces autophagy blockage in prostate cancer cells.

Oncotarget
2016-01 | Journal article
DOI: 10.18632/oncotarget.6415
PMID: 26625315
PMC: PMC4811481
Contributors: Ramos-Torres Á; Bort A; Morell C; Rodríguez-Henche N; Díaz-Laviada I
Source: Self-asserted source
Ines Diaz-Laviada via Europe PubMed Central
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Capsaicin induces autophagy in prostate cancer cells through reactive oxygen species generation

Febs Journal
2015 | Journal article
WOSUID:

WOS:000362570606169
Contributors: Ramos-Torres, A.; Morell, C.; Bort, A.; Rodriguez-Henche, N.; Diaz-Laviada, I.
Source: Self-asserted source
Ines Diaz-Laviada via ResearcherID

Dual effect of capsaicin on lipid accumulation in HepG2 cells

Febs Journal
2015 | Journal article
WOSUID:

WOS:000362570607021
Contributors: Bort, A. C.; Morell, M. C.; Ramos-Torres, A.; Diaz-Laviada, I.; Rodriguez-Henche, N.
Source: Self-asserted source
Ines Diaz-Laviada via ResearcherID

Novel cancer chemotherapy hits by molecular topology: dual Akt and Beta-catenin inhibitors

PLoS One
2015 | Journal article
DOI: 10.1371/journal.pone.0124244
Contributors: Zanni, R.; Galvez-Llompart, M.; Morell, C.; Rodríguez-Henche, N.; Díaz-Laviada, I.; Recio-Iglesias, M. C.; Garcia-Domenech, R.; Galvez, J.
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Ines Diaz-Laviada via ResearcherID
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The potential antitumor effects of capsaicin

Prog Drug Res
2014 | Journal article
SOURCE-WORK-ID:

0628170851305-2
Contributors: Díaz-Laviada, I.; Rodríguez-Henche, N.
Source: Self-asserted source
Ines Diaz-Laviada via ResearcherID

The potential antitumor effects of capsaicin

Progress in Drug Research
2014 | Book
DOI: 10.1007/978-3-0348-0828-6_8
EID:

2-s2.0-84901233786

Part of ISSN: 0071786X
Contributors: Díaz-Laviada, I.; Rodríguez-Henche, N.
Source: Self-asserted source
Ines Diaz-Laviada via Scopus - Elsevier

The potential antitumor effects of capsaicin.

Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques
2014-01 | Journal article
PMID: 24941670
Contributors: Díaz-Laviada I; Rodríguez-Henche N
Source: Self-asserted source
Ines Diaz-Laviada via Europe PubMed Central

Involvement of PPAR gamma in the antitumoral action of cannabinoids on hepatocellular carcinoma

Cell Death &amp; Disease
2013 | Journal article
DOI: 10.1038/cddis.2013.141
WOSUID:

WOS:000319824100007
Contributors: Vara, D.; Morell, C.; Rodriguez-Henche, N.; Diaz-Laviada, I.
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Ines Diaz-Laviada via ResearcherID
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Role of capsaicin in prostate cancer

Role of Capsaicin in Oxidative Stress and Cancer
2013 | Book chapter
Part of DOI: 10.1007/978-94-007-6317-3_3
EID:

2-s2.0-85028000684
Contributors: Díaz-Laviada, I.
Source: Self-asserted source
Ines Diaz-Laviada via Scopus - Elsevier

Synthetic cannabinoid quinones: preparation, in vitro antiproliferative effects and in vivo prostate antitumor activity

Eur J Med Chem
2013 | Journal article
DOI: 10.1016/j.ejmech.2013.09.043
Contributors: Morales, P.; Vara, D.; Goméz-Cañas, M.; Zúñiga, M. C.; Olea-Azar, C.; Goya, P.; Fernández-Ruiz, J.; Díaz-Laviada, I.; Jagerovic, N.
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Ines Diaz-Laviada via ResearcherID
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Guidelines for the use and interpretation of assays for monitoring autophagy

Autophagy
2012 | Journal article
DOI: 10.4161/auto.19496
WOSUID:

WOS:000305403400002
Contributors: Klionsky, Daniel J.; Abdalla, Fabio C.; Abeliovich, Hagai; Abraham, Robert T.; Acevedo-Arozena, Abraham; Adeli, Khosrow; Agholme, Lotta; Agnello, Maria; Agostinis, Patrizia; Aguirre-Ghiso, Julio A. et al.
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Ines Diaz-Laviada via ResearcherID
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Pepper capsaicinoids: Beneficial effects and mechanism of action

Peppers: Nutrition, Consumption and Health
2012 | Book chapter
EID:

2-s2.0-84892121752
Contributors: Rodríguez-Henche, N.; Díaz-Laviada, I.
Source: Self-asserted source
Ines Diaz-Laviada via Scopus - Elsevier

Quinone derivatives of chromenopyrazoles as cannabinoid ligands with antitumor activity in vivo

Abstracts of Papers of the American Chemical Society
2012 | Journal article
WOSUID:

WOS:000324621805665
Contributors: Morales, Paula; Vara, Diana; Gomez-Canas, Maria; Gomez-Ruiz, Maria; Goya, Pilar; Fernandez-Ruiz, Javier; Diaz-Laviada, Ines; Jagerovic, Nadine
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Ines Diaz-Laviada via ResearcherID

Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK-dependent activation of autophagy

Cell Death Differ
2011 | Journal article
DOI: 10.1038/cdd.2011.32
Contributors: Vara, D.; Salazar, M.; Olea-Herrero, N.; Guzmán, M.; Velasco, G.; Díaz-Laviada, I.
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Ines Diaz-Laviada via ResearcherID
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Preclinical evaluation of azathioprine plus buthionine sulfoximine in the treatment of human hepatocarcinoma and colon carcinoma

World J Gastroenterol
2011 | Journal article
DOI: 10.3748/wjg.v17.i34.3899
Contributors: Hernández-Breijo, B.; Monserrat, J.; Ramírez-Rubio, S.; Cuevas, E. P.; Vara, D.; Díaz-Laviada, I.; Fernández-Moreno, M. D.; Román, I. D.; Gisbert, J. P.; Guijarro, L. G.
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Ines Diaz-Laviada via ResearcherID
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The endocannabinoid system in prostate cancer

Nature Reviews Urology
2011 | Journal article
DOI: 10.1038/nrurol.2011.130
WOSUID:

WOS:000296265100005
Contributors: Diaz-Laviada, Ines
Source: Self-asserted source
Ines Diaz-Laviada via ResearcherID
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The role of AMPK in antitumoral action of cannabinoids on HCC

Febs Journal
2011 | Journal article
WOSUID:

WOS:000292333101521
Contributors: Vara, D.; Salazar, M.; Guzman, M.; Velasco, G.; Diaz-Laviada, I.
Source: Self-asserted source
Ines Diaz-Laviada via ResearcherID

The vanilloid capsaicin induces IL-6 secretion in prostate PC-3 cancer cells

Cytokine
2011 | Journal article
DOI: 10.1016/j.cyto.2011.03.010
Contributors: Malagarie-Cazenave, S.; Olea-Herrero, N.; Vara, D.; Morell, C.; Díaz-Laviada, I.
Source: Self-asserted source
Ines Diaz-Laviada via ResearcherID
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Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK-dependent activation of autophagy.

Cell death and differentiation
2011-06 | Journal article
DOI: 10.1038/cdd.2011.67
PMC: PMC3131954
Contributors: Vara D; Salazar M; Olea-Herrero N; Guzmán M; Velasco G; Díaz-Laviada I
Source: Self-asserted source
Ines Diaz-Laviada via Europe PubMed Central
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Effect of capsaicin on prostate cancer cells

Future Oncology
2010 | Journal article
DOI: 10.2217/fon.10.117
WOSUID:

WOS:000284192800008
Contributors: Diaz-Laviada, Ines
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Ines Diaz-Laviada via ResearcherID
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Capsaicin, a component of red peppers, induces expression of androgen receptor via PI3K and MAPK pathways in prostate LNCaP cells

Febs Letters
2009 | Journal article
DOI: 10.1016/j.febslet.2008.11.038
WOSUID:

WOS:000261949200025
Contributors: Malagarie-Cazenave, Sophie; Olea-Herrero, Nuria; Vara, Diana; Diaz-Laviada, Ines
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Ines Diaz-Laviada via ResearcherID
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Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)-Methanandamide and JWH-015: involvement of CB2

Br J Cancer
2009 | Journal article
DOI: 10.1038/sj.bjc.6605248
Contributors: Olea-Herrero, N.; Vara, D.; Malagarie-Cazenave, S.; Díaz-Laviada, I.
Source: Self-asserted source
Ines Diaz-Laviada via ResearcherID
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The cannabinoid R+ methanandamide induces IL-6 secretion by prostate cancer PC3 cells

J Immunotoxicol
2009 | Journal article
DOI: 10.3109/15476910903241696
Contributors: Olea-Herrero, N.; Vara, D.; Malagarie-Cazenave, S.; Díaz-Laviada, I.
Source: Self-asserted source
Ines Diaz-Laviada via ResearcherID
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Induction of the endoplasmic reticulum stress protein GADD153/CHOP by capsaicin in prostate PC-3 cells: a microarray study

Biochem Biophys Res Commun
2008 | Journal article
DOI: 10.1016/j.bbrc.2008.05.138
Contributors: Sánchez, A. M.; Martínez-Botas, J.; Malagarie-Cazenave, S.; Olea, N.; Vara, D.; Lasunción, M. A.; Díaz-Laviada, I.
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Ines Diaz-Laviada via ResearcherID
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