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Scopus Author ID: 8616797200

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Université libre de Bruxelles: 1050, Brussels, BE

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Université libre de Bruxelles

Works (36)

Reversal of vein of Galen aneurysmal malformation by stimulation of flow-mediated vessel fusion

2024-10-21 | Preprint
DOI: 10.1101/2024.10.18.618370
Contributors: Edwige Martin-Valiente; Yao Du; Chloé Goemans; Egor Zindy; Myckel Adam; Benoît Scheid; Miikka Vikkula; Boris Lubicz; Benoit Vanhollebeke; Nicolas Baeyens
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Crossref

Local angiogenic interplay of Vegfc/d and Vegfa controls brain region-specific emergence of fenestrated capillaries

eLife
2023-05-16 | Journal article
DOI: 10.7554/eLife.86066
Contributors: Sweta Parab; Olivia A Card; Qiyu Chen; Michelle America; Luke D Buck; Rachael E Quick; William F Horrigan; Gil Levkowitz; Benoit Vanhollebeke; Ryota L Matsuoka
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Heme-deficient metabolism and impaired cellular differentiation as an evolutionary trade-off for human infectivity in Trypanosoma brucei gambiense

Nature Communications
2022-11-18 | Journal article
DOI: 10.1038/s41467-022-34501-4
Contributors: Eva Horáková; Laurence Lecordier; Paula Cunha; Roman Sobotka; Piya Changmai; Catharina J. M. Langedijk; Jan Van Den Abbeele; Benoit Vanhollebeke; Julius Lukeš
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Crossref

Engineered Wnt7a ligands rescue blood brain barrier and neurobehavioral deficits in a mouse model of COVID-19

2022-06-03 | Preprint
DOI: 10.1101/2022.06.02.494552
Contributors: Troy N. Trevino; Avital B. Fogel; Jacob Class; Mark A. Sanborn; Benoit Vanhollebeke; Jalees Rehman; Leon M. Tai; Justin M. Richner; Sarah E. Lutz
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Crossref

An integrated model for Gpr124 function in Wnt7a/b signaling among vertebrates

Cell Reports
2022-05 | Journal article
DOI: 10.1016/j.celrep.2022.110902
Contributors: Michelle America; Naguissa Bostaille; Marie Eubelen; Maud Martin; Didier Y.R. Stainier; Benoit Vanhollebeke
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Crossref

Heme-deficient metabolism and impaired cellular differentiation as an evolutionary trade-off for human infectivity in Trypanosoma brucei gambiense

2020-09-08 | Preprint
DOI: 10.21203/rs.3.rs-49796/v1
Contributors: Eva Horáková; Laurence Lecordier; Paula Cunha; Roman Sobotka; Piya Changmai; Catharina Langedijk; Jan Van Den Abbeele; Benoit Vanhollebeke; Julius Lukes
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Crossref

APOLs with low pH dependence can kill all African trypanosomes

Nature Microbiology
2017 | Journal article
DOI: 10.1038/s41564-017-0034-1
EID:

2-s2.0-85029584525
Contributors: Fontaine, F.; Lecordier, L.; Vanwalleghem, G.; Uzureau, P.; Van Reet, N.; Fontaine, M.; Tebabi, P.; Vanhollebeke, B.; Büscher, P.; Pérez-Morga, D. et al.
Source: Self-asserted source
Benoit Vanhollebeke via Scopus - Elsevier

The Trypanosoma brucei TbHrg protein is a heme transporter involved in the regulation of stage-specific morphological transitions

Journal of Biological Chemistry
2017 | Journal article
DOI: 10.1074/jbc.M116.762997
EID:

2-s2.0-85018346018
Contributors: Horáková, E.; Changmai, P.; Vancová, M.; Sobotka, R.; Van Den Abbeele, J.; Vanhollebeke, B.; Lukeš, J.
Source: Self-asserted source
Benoit Vanhollebeke via Scopus - Elsevier

Apolipoproteins L control cell death triggered by TLR3/TRIF signaling in dendritic cells

European Journal of Immunology
2016 | Journal article
DOI: 10.1002/eji.201546252
EID:

2-s2.0-84982085555
Contributors: Uzureau, S.; Coquerelle, C.; Vermeiren, C.; Uzureau, P.; Van Acker, A.; Pilotte, L.; Monteyne, D.; Acolty, V.; Vanhollebeke, B.; Van den Eynde, B. et al.
Source: Self-asserted source
Benoit Vanhollebeke via Scopus - Elsevier

Naloxonazine, an Amastigote-Specific Compound, Affects Leishmania Parasites through Modulation of Host-Encoded Functions

PLoS Neglected Tropical Diseases
2016 | Journal article
DOI: 10.1371/journal.pntd.0005234
EID:

2-s2.0-85008697721
Contributors: De Muylder, G.; Vanhollebeke, B.; Caljon, G.; Wolfe, A.R.; McKerrow, J.; Dujardin, J.-C.
Source: Self-asserted source
Benoit Vanhollebeke via Scopus - Elsevier

Molecular insights into Adgra2/Gpr124 and Reck intracellular trafficking

Biology Open
2016-12-15 | Journal article
DOI: 10.1242/bio.021287
Contributors: Naguissa Bostaille; Anne Gauquier; Laure Twyffels; Benoit Vanhollebeke
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Crossref

Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent

eLife
2016-03-22 | Journal article
DOI: 10.7554/eLife.12613
Contributors: Hideo Imamura; Tim Downing; Frederik Van den Broeck; Mandy J Sanders; Suman Rijal; Shyam Sundar; An Mannaert; Manu Vanaerschot; Maya Berg; Géraldine De Muylder et al.
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Crossref

Defective adgra2 (gpr124) splicing and function in zebrafish ouchless mutants

Development
2016-01-01 | Journal article
DOI: 10.1242/dev.146803
Contributors: Naguissa Bostaille; Anne Gauquier; Didier Y. R. Stainier; David W. Raible; Benoit Vanhollebeke
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Crossref

Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis.

2015 | Journal article
DOI:

10.7554/eLife.06489

PMID:

26051822

PMC:

PMC4456509
Contributors: Vanhollebeke B; Stone OA; Bostaille N; Cho C; Zhou Y; Maquet E; Gauquier A; Cabochette P; Fukuhara S; Mochizuki N et al.
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central

Adaptation of Trypanosoma rhodesiense to hypohaptoglobinemic serum requires transcription of the APOL1 resistance gene in a RNA polymerase I locus.

2015-04 | Journal article
DOI:

10.1111/mmi.13036

PMID:

25899052
Contributors: Lecordier L; Uzureau P; Tebabi P; Brauner J; Benghiat FS; Vanhollebeke B; Pays E
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central
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Discovery of an ergosterol-signaling factor that regulates Trypanosoma brucei growth.

2015-02 | Journal article
DOI:

10.1194/jlr.M054643

PMID:

25424002
Contributors: Haubrich BA; Singha UK; Miller MB; Nes CR; Anyatonwu H; Lecordier L; Patkar P; Leaver DJ; Villalta F; Vanhollebeke B et al.
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central
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Translational profiling through biotinylation of tagged ribosomes in zebrafish.

2014-10 | Journal article
DOI:

10.1242/dev.111849

PMID:

25231762
Contributors: Housley MP; Reischauer S; Dieu M; Raes M; Stainier DY; Vanhollebeke B
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central
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The molecular arms race between African trypanosomes and humans.

2014-08 | Journal article
DOI:

10.1038/nrmicro3298

PMID:

24975321
Contributors: Pays E; Vanhollebeke B; Uzureau P; Lecordier L; Pérez-Morga D
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central
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Mechanism of Trypanosoma brucei gambiense resistance to human serum.

2013-09 | Journal article
DOI:

10.1038/nature12516

PMID:

23965626
Contributors: Uzureau P; Uzureau S; Lecordier L; Fontaine F; Tebabi P; Homblé F; Grélard A; Zhendre V; Nolan DP; Lins L et al.
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central
grade
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Association of trypanolytic ApoL1 variants with kidney disease in African Americans.

2010-08 | Journal article
DOI:

10.1126/science.1193032

PMID:

20647424

PMC:

PMC2980843
Contributors: Genovese G; Friedman DJ; Ross MD; Lecordier L; Uzureau P; Freedman BI; Bowden DW; Langefeld CD; Oleksyk TK; Uscinski Knob AL et al.
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central
grade
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Cellular and molecular remodeling of the endocytic pathway during differentiation of Trypanosoma brucei bloodstream forms.

2010-08 | Journal article
DOI:

10.1128/EC.00076-10

PMID:

20581292

PMC:

PMC2918936
Contributors: Vanhollebeke B; Uzureau P; Monteyne D; Pérez-Morga D; Pays E
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central
grade
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The trypanolytic factor of human serum: many ways to enter the parasite, a single way to kill.

2010-05 | Journal article
DOI:

10.1111/j.1365-2958.2010.07156.x

PMID:

20398209
Contributors: Vanhollebeke B; Pays E
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central
grade
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Crystal structures of Trypanosoma brucei sterol 14alpha-demethylase and implications for selective treatment of human infections.

2010-01 | Journal article
DOI:

10.1074/jbc.M109.067470

PMID:

19923211

PMC:

PMC2804335
Contributors: Lepesheva GI; Park HW; Hargrove TY; Vanhollebeke B; Wawrzak Z; Harp JM; Sundaramoorthy M; Nes WD; Pays E; Chaudhuri M et al.
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central
grade
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C-terminal mutants of apolipoprotein L-I efficiently kill both Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense.

2009-12 | Journal article
DOI:

10.1371/journal.ppat.1000685

PMID:

19997494

PMC:

PMC2778949
Contributors: Lecordier L; Vanhollebeke B; Poelvoorde P; Tebabi P; Paturiaux-Hanocq F; Andris F; Lins L; Pays E
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central
grade
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Human innate immunity against African trypanosomes.

2009-10 | Journal article
DOI:

10.1016/j.coi.2009.05.024

PMID:

19559585
Contributors: Pays E; Vanhollebeke B
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central
grade
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[The controversial story of the human trypanolytic factor].

2008-10 | Journal article
DOI:

10.1051/medsci/20082410792

PMID:

18950568
Contributors: Pays E; Vanhollebeke B
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central
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Mutual self-defence: the trypanolytic factor story.

2008-07 | Journal article
DOI:

10.1016/j.micinf.2008.07.020

PMID:

18675374
Contributors: Pays E; Vanhollebeke B
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central
grade
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A haptoglobin-hemoglobin receptor conveys innate immunity to Trypanosoma brucei in humans.

2008-05 | Journal article
DOI:

10.1126/science.1156296

PMID:

18451305
Contributors: Vanhollebeke B; De Muylder G; Nielsen MJ; Pays A; Tebabi P; Dieu M; Raes M; Moestrup SK; Pays E
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central
grade
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Human serum lyses Trypanosoma brucei by triggering uncontrolled swelling of the parasite lysosome.

2007 | Journal article
DOI:

10.1111/j.1550-7408.2007.00285.x

PMID:

17910690
Contributors: Vanhollebeke B; Lecordier L; Perez-Morga D; Amiguet-Vercher A; Pays E
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central
grade
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Distinct roles of haptoglobin-related protein and apolipoprotein L-I in trypanolysis by human serum.

2007-03 | Journal article
DOI:

10.1073/pnas.0609902104

PMID:

17360487

PMC:

PMC1820718
Contributors: Vanhollebeke B; Nielsen MJ; Watanabe Y; Truc P; Vanhamme L; Nakajima K; Moestrup SK; Pays E
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central
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Human Trypanosoma evansi infection linked to a lack of apolipoprotein L-I.

2006-12 | Journal article
DOI:

10.1056/NEJMoa063265

PMID:

17192540
Contributors: Vanhollebeke B; Truc P; Poelvoorde P; Pays A; Joshi PP; Katti R; Jannin JG; Pays E
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central
grade
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[Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor].

2006-11 | Journal article
DOI:

10.1051/medsci/20062211914

PMID:

17101086
Contributors: Baral TN; Magez S; Stijlemans B; Conrath K; Vanhollebeke B; Pays E; Muyldermans S; De Baetselier P
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central
grade
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The function of apolipoproteins L.

2006-09 | Journal article
DOI:

10.1007/s00018-006-6091-x

PMID:

16847577
Contributors: Vanhollebeke B; Pays E
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central
grade
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The trypanolytic factor of human serum.

2006-06 | Journal article
DOI:

10.1038/nrmicro1428

PMID:

16710327
Contributors: Pays E; Vanhollebeke B; Vanhamme L; Paturiaux-Hanocq F; Nolan DP; Pérez-Morga D
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central
grade
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Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor.

2006-05 | Journal article
DOI:

10.1038/nm1395

PMID:

16604085
Contributors: Baral TN; Magez S; Stijlemans B; Conrath K; Vanhollebeke B; Pays E; Muyldermans S; De Baetselier P
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central
grade
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Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes.

2005-07 | Journal article
DOI:

10.1126/science.1114566

PMID:

16020735
Contributors: Pérez-Morga D; Vanhollebeke B; Paturiaux-Hanocq F; Nolan DP; Lins L; Homblé F; Vanhamme L; Tebabi P; Pays A; Poelvoorde P et al.
Source: Self-asserted source
Benoit Vanhollebeke via Europe PubMed Central
grade
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