Personal information

Emails & domains

Verified email domains

Activities

Collapse all

Employment (1)

University of Oxford: Oxford, Oxfordshire, GB

(Weatherall Institute of Molecular Medicine; Target Discovery Institute)
Employment
Source: check_circle
ORCID Integration at the University of Oxford

Education and qualifications (2)

University of Oxford: Oxford, Oxfordshire, GB

1993-10 to 1997-05 | D.Phil (Sir William Dunn School of Pathology)
Education
Source: Self-asserted source
Simon Brackenridge

University of Edinburgh: Edinburgh, GB

1989-10 to 1993-06 | Bachelor of Science (Institute of Cell and Molecular Biology)
Education
Source: Self-asserted source
Simon Brackenridge

Works (27)

Regulation of the cell surface expression of classical and non-classical MHC proteins by the human cytomegalovirus UL40 and rhesus cytomegalovirus Rh67 proteins

Journal of Virology
2024-09-17 | Journal article
DOI: 10.1128/jvi.01206-24
Contributors: Simon Brackenridge; Nessy John; Wanlin He; Klaus Früh; Persephone Borrow; Andrew McMichael; Felicia Goodrum
Source: check_circle
Crossref

A high affinity monoclonal antibody against HLA-E-VL9 enhances natural killer cell anti-tumor killing

2024-07-11 | Preprint
DOI: 10.1101/2024.07.08.602401
Contributors: Joyce K. Hwang; Daniel J. Marston; Daniel Wrapp; Dapeng Li; Marina Tuyishime; Simon Brackenridge; Brianna Rhodes; Max Quastel; A. Brenda Kapingidza; Jacob Gater et al.
Source: check_circle
Crossref

Intracellular trafficking of HLA-E and its regulation

Journal of Experimental Medicine
2023-08-07 | Journal article
DOI: 10.1084/jem.20221941
Contributors: Wanlin He; Ester Gea-Mallorquí; Huw Colin-York; Marco Fritzsche; Geraldine M. Gillespie; Simon Brackenridge; Persephone Borrow; Andrew J. McMichael
Source: check_circle
Crossref

HLA-E–restricted SARS-CoV-2–specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation

Science Immunology
2023-06-30 | Journal article
DOI: 10.1126/sciimmunol.abl8881
Contributors: Hongbing Yang; Hong Sun; Simon Brackenridge; Xiaodong Zhuang; Peter A C Wing; Max Quastel; Lucy Walters; Lee Garner; Beibei Wang; Xuan Yao et al.
Source: check_circle
Crossref

Regulation of the cell surface expression of classical and non-classical MHC proteins by the human cytomegalovirus UL40 and rhesus cytomegalovirus rh67 proteins

2022-07-23 | Preprint
DOI: 10.1101/2022.07.22.501209
Contributors: Simon Brackenridge; Persephone Borrow; Andrew McMichael
Source: check_circle
Crossref

Mapping the epitopes of the Human Leukocyte Antigen E antibodies 3D12 and 4D12

2022-05-29 | Preprint
DOI: 10.1101/2022.05.27.493692
Contributors: Simon Brackenridge; Persephone Borrow; Andrew J. McMichael
Source: check_circle
Crossref

Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity

Communications Biology
2022-03-28 | Journal article
DOI: 10.1038/s42003-022-03183-5
Contributors: Dapeng Li; Simon Brackenridge; Lucy C. Walters; Olivia Swanson; Karl Harlos; Daniel Rozbesky; Derek W. Cain; Kevin Wiehe; Richard M. Scearce; Maggie Barr et al.
Source: check_circle
Crossref

HLA-E–restricted, Gag-specific CD8 + T cells can suppress HIV-1 infection, offering vaccine opportunities

Science Immunology
2021-03-04 | Journal article
DOI: 10.1126/sciimmunol.abg1703
Contributors: Hongbing Yang; Margarida Rei; Simon Brackenridge; Elena Brenna; Hong Sun; Shaheed Abdulhaqq; Michael K. P. Liu; Weiwei Ma; Prathiba Kurupati; Xiaoning Xu et al.
Source: check_circle
Crossref

HLA binding of self-peptides is biased towards proteins with specific molecular functions

2021-02-17 | Preprint
DOI: 10.1101/2021.02.16.431395
Contributors: Vadim Karnaukhov; Wayne Paes; Isaac B. Woodhouse; Thomas Partridge; Annalisa Nicastri; Simon Brackenridge; Dmitrii Scherbinin; Dmitry M. Chudakov; Ivan V. Zvyagin; Nicola Ternette et al.
Source: check_circle
Crossref

HLA-E restricted, HIV-1 suppressing, Gag specific CD8+ T cells offer universal vaccine opportunities

2020-12-02 | Preprint
DOI: 10.1101/2020.12.01.406066
Contributors: Hongbing Yang; Margarida Rei; Simon Brackenridge; Elena Brenna; Hong Sun; Shaheed Abdulhaqq; Michael K P Liu; Weiwei Ma; Prathiba Kurupati; Xiaoning Xu et al.
Source: check_circle
Crossref

Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity

eLife
2020-07-27 | Journal article
DOI: 10.7554/eLife.58128
Contributors: Juan L Mendoza; Suzanne Fischer; Marvin H Gee; Lilian H Lam; Simon Brackenridge; Fiona M Powrie; Michael Birnbaum; Andrew J McMichael; K Christopher Garcia; Geraldine M Gillespie
Source: check_circle
Crossref

Author Correction: Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding

Nature Communications
2018-11-13 | Journal article
DOI: 10.1038/s41467-018-07304-9
Contributors: Lucy C. Walters; Karl Harlos; Simon Brackenridge; Daniel Rozbesky; Jordan R. Barrett; Vitul Jain; Thomas S. Walter; Chris A. O’Callaghan; Persephone Borrow; Mireille Toebes et al.
Source: check_circle
Crossref

Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding

Nature Communications
2018-08-07 | Journal article
DOI: 10.1038/s41467-018-05459-z
Contributors: Lucy C. Walters; Karl Harlos; Simon Brackenridge; Daniel Rozbesky; Jordan R. Barrett; Vitul Jain; Thomas S. Walter; Chris A. O’Callaghan; Persephone Borrow; Mireille Toebes et al.
Source: check_circle
Crossref

Broadly targeted CD8⁺ T cell responses restricted by major histocompatibility complex E.

2016-02 | Journal article
DOI: 10.1126/science.aac9475
PMID: 26797147
PMC: PMC4769032
Contributors: Hansen SG; Wu HL; Burwitz BJ; Hughes CM; Hammond KB; Ventura AB; Reed JS; Gilbride RM; Ainslie E; Morrow DW et al.
Source: Self-asserted source
Simon Brackenridge via Europe PubMed Central

Recombination-mediated escape from primary CD8+ T cells in acute HIV-1 infection.

2014-09 | Journal article
DOI: 10.1186/preaccept-1035836021115701
PMID: 25212771
PMC: PMC4180588
Contributors: Ritchie AJ; Cai F; Smith NM; Chen S; Song H; Brackenridge S; Abdool Karim SS; Korber BT; McMichael AJ; Gao F et al.
Source: Self-asserted source
Simon Brackenridge via Europe PubMed Central

Vertical T cell immunodominance and epitope entropy determine HIV-1 escape.

2013-01 | Journal article
DOI: 10.1172/jci65330
PMID: 23221345
PMC: PMC3533301
Contributors: Liu MK; Hawkins N; Ritchie AJ; Ganusov VV; Whale V; Brackenridge S; Li H; Pavlicek JW; Cai F; Rose-Abrahams M et al.
Source: Self-asserted source
Simon Brackenridge via Europe PubMed Central

The HIV-1 protective -35SNP effect in Caucasians is CD8 T cell mediated.

2012 | Journal article
DOI: 10.1186/1742-4690-9-s2-p281
PMC: PMC3441471
Contributors: Corrah T; Brackenridge S; Goonetilleke N; Yang H; Deeks S; Dorrell L; Cohen M; McMichael A
Source: Self-asserted source
Simon Brackenridge via Europe PubMed Central

An early HIV mutation within an HLA-B*57-restricted T cell epitope abrogates binding to the killer inhibitory receptor 3DL1.

2011-06 | Journal article
DOI: 10.1128/jvi.00238-11
PMID: 21430058
PMC: PMC3094954
Contributors: Brackenridge S; Evans EJ; Toebes M; Goonetilleke N; Liu MK; di Gleria K; Schumacher TN; Davis SJ; McMichael AJ; Gillespie GM
Source: Self-asserted source
Simon Brackenridge via Europe PubMed Central

Differences in HIV-specific T cell responses between HIV-exposed and -unexposed HIV-seronegative individuals.

2011-04 | Journal article
DOI: 10.1128/jvi.02444-10
PMID: 21270166
PMC: PMC3067859
Contributors: Ritchie AJ; Campion SL; Kopycinski J; Moodie Z; Wang ZM; Pandya K; Moore S; Liu MK; Brackenridge S; Kuldanek K et al.
Source: Self-asserted source
Simon Brackenridge via Europe PubMed Central

Reappraisal of the relationship between the HIV-1-protective single-nucleotide polymorphism 35 kilobases upstream of the HLA-C gene and surface HLA-C expression.

2011-04 | Journal article
DOI: 10.1128/jvi.02276-10
PMID: 21248048
PMC: PMC3067890
Contributors: Corrah TW; Goonetilleke N; Kopycinski J; Deeks SG; Cohen MS; Borrow P; McMichael A; Brackenridge S
Source: Self-asserted source
Simon Brackenridge via Europe PubMed Central

OA06-04. The role of early T-cell responses in subjects with acute HIV-1 infection.

2009 | Journal article
DOI: 10.1186/1742-4690-6-s3-o40
PMC: PMC2767563
Contributors: Liu M; Ferrari G; Salazar J; Keele B; Tanner R; Hraber P; Giorgi E; Ganusov V; Learn G; Salazar M et al.
Source: Self-asserted source
Simon Brackenridge via Europe PubMed Central

P08-05. Does increased expression of HLA-C allow better control of HIV-1 viral load?

2009 | Journal article
DOI: 10.1186/1742-4690-6-s3-p113
PMC: PMC2767597
Contributors: Brackenridge S; Corrah T; Haygreen E; Lavender K; Dong T; Goonetilleke N; Borrow P; McMichael A
Source: Self-asserted source
Simon Brackenridge via Europe PubMed Central

A novel CD45 transcript involving the alternative splicing of a new exon is widely distributed in lymphoid tissues.

2004-12 | Journal article
DOI: 10.1016/j.humimm.2004.08.181
PMID: 15603882
Contributors: Li D; Brackenridge S; Screaton GR
Source: Self-asserted source
Simon Brackenridge via Europe PubMed Central

Efficient use of a 'dead-end' GA 5' splice site in the human fibroblast growth factor receptor genes.

2003-04 | Journal article
DOI: 10.1093/emboj/cdg163
PMID: 12660168
PMC: PMC152907
Contributors: Brackenridge S; Wilkie AO; Screaton GR
Source: Self-asserted source
Simon Brackenridge via Europe PubMed Central

Recruitment of a basal polyadenylation factor by the upstream sequence element of the human lamin B2 polyadenylation signal.

2000-04 | Journal article
DOI: 10.1128/mcb.20.8.2660-2669.2000
PMID: 10733568
PMC: PMC85481
Contributors: Brackenridge S; Proudfoot NJ
Source: Self-asserted source
Simon Brackenridge via Europe PubMed Central

The upstream sequence element of the C2 complement poly(A) signal activates mRNA 3' end formation by two distinct mechanisms.

1998-08 | Journal article
DOI: 10.1101/gad.12.16.2522
PMID: 9716405
PMC: PMC317083
Contributors: Moreira A; Takagaki Y; Brackenridge S; Wollerton M; Manley JL; Proudfoot NJ
Source: Self-asserted source
Simon Brackenridge via Europe PubMed Central

Transcription and polyadenylation in a short human intergenic region.

1997-06 | Journal article
DOI: 10.1093/nar/25.12.2326
PMID: 9171082
PMC: PMC146771
Contributors: Brackenridge S; Ashe HL; Giacca M; Proudfoot NJ
Source: Self-asserted source
Simon Brackenridge via Europe PubMed Central
How many people are using ORCID?