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Employment (4)

Stanford University: Stanford, CA, US

2018-09-01 to present | Assistant Professor (Chemistry)
Employment
Source: Self-asserted source
Laura Dassama

Harvard Medical School: Boston, MA, US

2017 to 2018-08-31 | Research Fellow (Pediatrics)
Employment
Source: Self-asserted source
Laura Dassama

Dana Farber Cancer Institute: Boston, MA, US

2017 to 2018-08-31 | Fellow (Pediatric Oncology)
Employment
Source: Self-asserted source
Laura Dassama

Children's Hospital Boston: Boston, MA, US

2017 to 2018-08-31 | Research Associate (Hematology/Oncology)
Employment
Source: Self-asserted source
Laura Dassama

Education and qualifications (3)

Northwestern University: Evanston, IL, US

2013 to 2017 (Molecular Biosciences)
Education
Source: Self-asserted source
Laura Dassama

Pennsylvania State University: University Park, PA, US

2007 to 2013 | Doctor of Philosophy (Biochemistry and Molecular Biology)
Education
Source: Self-asserted source
Laura Dassama

Temple University: Philadelphia, PA, US

2004 to 2007
Education
Source: Self-asserted source
Laura Dassama

Works (39)

Investigating the Effect of Membrane Composition on the Selective Ammonium Transport of E. coli AmtB Membrane Proteins

2025-04-08 | Preprint
DOI: 10.26434/chemrxiv-2025-0ksxc
Contributors: Brandon Clark; Jonathan Chou; Veronica Stafford; Franklin Lurie; Laura Dassama; William Tarpeh
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Crossref

Engineering Cell-Specific Protein Delivery Vehicles for Erythroid Lineage Cells

ACS Bio & Med Chem Au
2025-02-27 | Journal article
DOI: 10.1021/acsbiomedchemau.4c00098
Contributors: Mekedlawit T. Setegne; Aidan T. Cabral; Anushri Tiwari; Fangfang Shen; Hawa Racine Thiam; Laura M. K. Dassama
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Protein-Based Degraders: From Chemical Biology Tools to Neo-Therapeutics

Chemical Reviews
2025-02-26 | Journal article
DOI: 10.1021/acs.chemrev.4c00595
Contributors: Lisha Ou; Mekedlawit T. Setegne; Jeandele Elliot; Fangfang Shen; Laura M. K. Dassama
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Identifying Opportunity Targets in Gram-Negative Pathogens for Infectious Disease Mitigation

ACS Central Science
2025-01-22 | Journal article
DOI: 10.1021/acscentsci.4c01437
Contributors: Isaac A. Paddy; Laura M. K. Dassama
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Lipid Trafficking in Diverse Bacteria

Accounts of Chemical Research
2025-01-07 | Journal article
DOI: 10.1021/acs.accounts.4c00540
Contributors: Jonathan Chiu-Chun Chou; Laura M. K. Dassama
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Unveiling of a messenger: Gut microbes make a neuroactive signal.

Cell
2024-06-06 | Journal article
DOI: 10.1016/j.cell.2024.05.014
PMID: 38848674
Part of ISSN: 1097-4172
Contributors: Poulami Chatterjee; Laura M Dassama
Source: check_circle
Stanford University

Novel sterol binding domains in bacteria

eLife
2024-02-08 | Journal article
DOI: 10.7554/eLife.90696.3
Contributors: Liting Zhai; Amber C Bonds; Clyde A Smith; Hannah Oo; Jonathan Chiu-Chun Chou; Paula V Welander; Laura MK Dassama
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Crossref

Novel sterol binding domains in bacteria

eLife
2024-02-08 | Journal article
DOI: 10.7554/eLife.90696
Contributors: Liting Zhai; Amber C Bonds; Clyde A Smith; Hannah Oo; Jonathan Chiu-Chun Chou; Paula V Welander; Laura MK Dassama
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Rapid proteome-wide prediction of lipid-interacting proteins through ligand-guided structural genomics.

bioRxiv : the preprint server for biology
2024-01-30 | Journal article
DOI: 10.1101/2024.01.26.577452
PMC: PMC10862712
PMID: 38352308
Contributors: Jonathan Chiu-Chun Chou; Cassandra M Decosto; Poulami Chatterjee; Laura M Dassama
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Stanford University

Novel sterol binding domains in bacteria

2024-01-11 | Preprint
DOI: 10.7554/eLife.90696.2
Contributors: Liting Zhai; Amber C. Bonds; Clyde A. Smith; Hannah Oo; Jonathan Chiu-Chun Chou; Paula V. Welander; Laura M. K. Dassama
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Crossref

Opportunities and challenges of protein-based targeted protein degradation

Chemical Science
2023 | Journal article
DOI: 10.1039/D3SC02361C
Contributors: Fangfang Shen; Laura M. K. Dassama
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Novel sterol binding domains in bacteria

2023-10-17 | Preprint
DOI: 10.7554/eLife.90696.1
Contributors: Liting Zhai; Amber C. Bonds; Clyde A. Smith; Hannah Oo; Jonathan Chiu-Chun Chou; Paula V. Welander; Laura M. K. Dassama
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Structures and Mechanisms of a Novel Bacterial Transport System for Fatty Acids

ChemBioChem
2023-08 | Journal article
DOI: 10.1002/cbic.202300156
Contributors: Liting Zhai; Jonathan Chiu‐Chun Chou; Hannah Oo; Laura M. K. Dassama
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Evolution of nanobodies specific for BCL11A

Proceedings of the National Academy of Sciences
2023-01-17 | Journal article
DOI: 10.1073/pnas.2218959120
Contributors: Maolu Yin; Manizheh Izadi; Karin Tenglin; Thibault Viennet; Liting Zhai; Ge Zheng; Haribabu Arthanari; Laura M. K. Dassama; Stuart H. Orkin
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A Cell-Permeant Nanobody-Based Degrader That Induces Fetal Hemoglobin

ACS Central Science
2022-12-28 | Journal article
DOI: 10.1021/acscentsci.2c00998
Contributors: Fangfang Shen; Ge Zheng; Mekedlawit Setegne; Karin Tenglin; Manizheh Izadi; Henry Xie; Liting Zhai; Stuart H. Orkin; Laura M. K. Dassama
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A cell-permeant nanobody-based degrader that induces fetal hemoglobin

2022-06-07 | Preprint
DOI: 10.1101/2022.06.07.495197
Contributors: Fangfang Shen; Ge Zheng; Mekedlawit Setegne; Karin Tenglin; Manizheh Izada; Henry Xie; Liting Zhai; Stuart H. Orkin; Laura M. K. Dassama
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Crossref

Novel sterol binding domains in bacteria

2022-05-16 | Preprint
DOI: 10.1101/2022.05.15.491920
Contributors: Liting Zhai; Amber C. Bonds; Clyde A. Smith; Hannah Oo; Jonathan Chiu-Chun Chou; Paula V. Welander; Laura M. K. Dassama
Source: check_circle
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The enzymology of oxazolone and thioamide synthesis in methanobactin.

Methods in enzymology
2021-01-01 | Journal article
DOI: 10.1016/bs.mie.2021.04.008
PMID: 34325792
WOSUID:

MEDLINE:34325792

Part of ISSN: 1557-7988
Part of ISSN: 0076-6879
Contributors: Chou, Jonathan Chiu-Chun; Stafford, Veronica E.; Kenney, Grace E.; Dassama, Laura M.
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Stanford University

Nuclear Resonance Vibrational Spectroscopic Definition of the Facial Triad FeIV═O Intermediate in Taurine Dioxygenase: Evaluation of Structural Contributions to Hydrogen Atom Abstraction

Journal of the American Chemical Society
2020-11-04 | Journal article
DOI: 10.1021/jacs.0c08903
Contributors: Martin Srnec; Shyam R. Iyer; Laura M. K. Dassama; Kiyoung Park; Shaun D. Wong; Kyle D. Sutherlin; Yoshitaka Yoda; Yasuhiro Kobayashi; Masayuki Kurokuzu; Makina Saito et al.
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MbnH is a diheme MauG-like protein associated with microbial copper homeostasis

Journal of Biological Chemistry
2019-11 | Journal article
DOI: 10.1074/jbc.RA119.010202
Contributors: Grace E. Kenney; Laura M.K. Dassama; Anastasia C. Manesis; Matthew O. Ross; Siyu Chen; Brian M. Hoffman; Amy C. Rosenzweig
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Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis

Nature Genetics
2019-07-28 | Journal article
DOI: 10.1038/s41588-019-0453-4
Contributors: Falak Sher; Mir Hossain; Davide Seruggia; Vivien A. C. Schoonenberg; Qiuming Yao; Paolo Cifani; Laura M. K. Dassama; Mitchel A. Cole; Chunyan Ren; Divya S. Vinjamur et al.
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The biosynthesis of methanobactin

Science
2018-03-23 | Journal article
DOI: 10.1126/science.aap9437
Contributors: Grace E. Kenney; Laura M. K. Dassama; Maria-Eirini Pandelia; Anthony S. Gizzi; Ryan J. Martinie; Peng Gao; Caroline J. DeHart; Luis F. Schachner; Owen S. Skinner; Soo Y. Ro et al.
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Methanobactins: from genome to function

Metallomics
2017 | Journal article
DOI: 10.1039/c6mt00208k
Part of ISSN: 1756-5901
Contributors: Laura M. K. Dassama; Grace E. Kenney; Amy C. Rosenzweig
Source: Self-asserted source
Laura Dassama via Crossref Metadata Search
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Copper transport in methanotrophic bacteria

2017-04-02 | Conference paper
WOSUID:

WOS:000430569103238

Part of ISSN: 0065-7727
Contributors: Kenney, Grace; Dassama, Laura; Ro, Soo; Rosenzweig, Amy
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Stanford University

Bacterial copper acquisition

2017-04-01 | Conference paper
WOSUID:

WOS:000405461402700

Part of ISSN: 1530-6860
Part of ISSN: 0892-6638
Contributors: Rosenzweig, Amy C.; Kenney, Grace E.; Dassama, Laura M. K.; Ro, Soo Y.
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Stanford University

O-H Activation by an Unexpected Ferryl Intermediate during Catalysis by 2-Hydroxyethylphosphonate Dioxygenase

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
2017-02-08 | Journal article
DOI: 10.1021/jacs.6b12147
PMC: PMC5302023
PMID: 28092705
WOSUID:

WOS:000393848400055

Part of ISSN: 0002-7863
Contributors: Peck, Spencer C.; Wang, Chen; Dassama, Laura M. K.; Zhang, Bo; Guo, Yisong; Rajakovich, Lauren J.; Bollinger, J. Martin; Krebs, Carsten; van der Donk, Wilfred A.
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Stanford University

Methanobactin transport machinery

Proceedings of the National Academy of Sciences
2016-11-02 | Journal article
DOI: 10.1073/pnas.1603578113
Part of ISSN: 0027-8424
Contributors: Laura M. K. Dassama; Grace E. Kenney; Soo Y. Ro; Eliza L. Zielazinski; Amy C. Rosenzweig
Source: Self-asserted source
Laura Dassama via Crossref Metadata Search
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Methanobactin periplasmic binding protein

2016-10 | Other
DOI: 10.2210/pdb5icq/pdb
Contributors: L.M.K. Dassama; A.C. Rosenzweig
Source: Self-asserted source
Laura Dassama via Crossref Metadata Search

Direct Measurement of the Radical Translocation Distance in the Class I Ribonucleotide Reductase from Chlamydia trachomatis

JOURNAL OF PHYSICAL CHEMISTRY B
2015-10-29 | Journal article
DOI: 10.1021/acs.jpcb.5b04057
PMC: PMC5840866
PMID: 26087051
WOSUID:

WOS:000363994000035

Part of ISSN: 1520-6106
Contributors: Livada, Jovan; Martinie, Ryan J.; Dassama, Laura M. K.; Krebs, Carsten; Bollinger, J. Martin; Silakov, Alexey
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Stanford University

Direct Measurement of the Radical Translocation Distance in the Class I Ribonucleotide Reductase from Chlamydia trachomatis

The Journal of Physical Chemistry B
2015-06 | Journal article
DOI: 10.1021/acs.jpcb.5b04067
Part of ISSN: 1520-6106
Contributors: Jovan Livada; Ryan J. Martinie; Laura M. K. Dassama; Carsten Krebs; J. Martin Bollinger; Alexey Silakov
Source: Self-asserted source
Laura Dassama via Crossref Metadata Search

Geometric and Electronic Structure of the Mn(IV)Fe(III) Cofactor in Class Ic Ribonucleotide Reductase: Correlation to the Class Ia Binuclear Non-Heme Iron Enzyme.

Journal of the American Chemical Society
2013-11-20 | Journal article
DOI: 10.1021/ja409510d
PMID: 24131208
Part of ISSN: 0002-7863
Contributors: Kwak, Yeonju; Jiang, Wei; Dassama, Laura MK; Park, Kiyoung; Bell, Caleb B.; Liu, Lei V.; Wong, Shaun D.; Saito, Makina; Kobayashi, Yasuhiro; Kitao, Shinji et al.
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Stanford University

A 2.8 Å Fe–Fe Separation in the Fe2III/IV Intermediate, X, from Escherichia coli Ribonucleotide Reductase

Journal of the American Chemical Society
2013-10 | Journal article
DOI: 10.1021/ja407438p
Part of ISSN: 0002-7863
Contributors: Laura M. K. Dassama; Alexey Silakov; Courtney M. Krest; Julio C. Calixto; Carsten Krebs; J. Martin Bollinger; Michael T. Green
Source: Self-asserted source
Laura Dassama via Crossref Metadata Search
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Structural Basis for Assembly of the MnIV/FeIII Cofactor in the Class Ic Ribonucleotide Reductase from Chlamydia trachomatis

Biochemistry
2013-09-03 | Journal article
DOI: 10.1021/bi400819x
Part of ISSN: 0006-2960
Contributors: Laura M. K. Dassama; Carsten Krebs; J. Martin Bollinger; Amy C. Rosenzweig; Amie K. Boal
Source: Self-asserted source
Laura Dassama via Crossref Metadata Search
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Novel approaches for the accumulation of oxygenated intermediates to multi-millimolar concentrations

COORDINATION CHEMISTRY REVIEWS
2013-01-01 | Journal article
DOI: 10.1016/j.ccr.2012.06.020
PMC: PMC3870000
PMID: 24368870
WOSUID:

WOS:000312972700019

Part of ISSN: 0010-8545
Contributors: Krebs, Carsten; Dassama, Laura M. K.; Matthews, Megan L.; Jiang, Wei; Price, John C.; Korboukh, Victoria; Li, Ning; Bollinger, J. Martin
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Stanford University

Radical-Translocation Intermediates and Hurdling of Pathway Defects in “Super-oxidized” (MnIV/FeIV) Chlamydia trachomatis Ribonucleotide Reductase

Journal of the American Chemical Society
2012 | Journal article
DOI: 10.1021/ja309468s
Part of ISSN: 0002-7863
Contributors: Laura M. K. Dassama; Wei Jiang; Paul T. Varano; Maria-Eirini Pandelia; Denise A. Conner; Jiajia Xie; J. Martin Bollinger; Carsten Krebs
Source: Self-asserted source
Laura Dassama via Crossref Metadata Search
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Chlamydia trachomatis NrdB with a Mn/Fe cofactor (procedure 1 - high Mn)

2012-02 | Other
DOI: 10.2210/pdb4d8f/pdb
Contributors: L.M.K. Dassama; A.K. Boal; C. Krebs; A.C. Rosenzweig; J.M. Bollinger Jr.
Source: Self-asserted source
Laura Dassama via Crossref Metadata Search

Chlamydia trachomatis NrdB with a Mn/Fe cofactor (procedure 2 - low Mn)

2012-02 | Other
DOI: 10.2210/pdb4d8g/pdb
Contributors: L.M.K. Dassama; A.K. Boal; C. Krebs; A.C. Rosenzweig; J.M. Bollinger Jr.
Source: Self-asserted source
Laura Dassama via Crossref Metadata Search

O2-Evolving Chlorite Dismutase as a Tool for Studying O2-Utilizing Enzymes

Biochemistry
2012-02 | Journal article
DOI: 10.1021/bi201906x
Part of ISSN: 0006-2960
Contributors: Laura M. K. Dassama; Timothy H. Yosca; Denise A. Conner; Michael H. Lee; Béatrice Blanc; Bennett R. Streit; Michael T. Green; Jennifer L. DuBois; Carsten Krebs; J. Martin Bollinger
Source: Self-asserted source
Laura Dassama via Crossref Metadata Search
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Evidence That the β Subunit of Chlamydia trachomatis Ribonucleotide Reductase Is Active with the Manganese Ion of Its Manganese(IV)/Iron(III) Cofactor in Site 1

Journal of the American Chemical Society
2012-01 | Journal article
DOI: 10.1021/ja211314p
Part of ISSN: 0002-7863
Contributors: Laura M. K. Dassama; Amie K. Boal; Carsten Krebs; Amy C. Rosenzweig; J. Martin Bollinger
Source: Self-asserted source
Laura Dassama via Crossref Metadata Search
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Peer review (4 reviews for 4 publications/grants)

Review activity for ACS central science. (1)
Review activity for ACS chemical biology. (1)
Review activity for Biochemistry. (1)
Review activity for Journal of the American Chemical Society. (1)
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