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Employment (5)

Institute of Science Tokyo: Tokyo, JP

2025-02-01 to present | Professor (Medical Research Institute)
Employment
Source: Self-asserted source
Kazuo Takayama

Kyoto University: Kyoto, JP

2020-03-01 to 2025-03-31 | Junior Associate Professor (Center for iPS Cell Research and Application)
Employment
Source: Self-asserted source
Kazuo Takayama

Japan Science and Technology Agency: Saitama, JP

2016-10-01 to 2020-03-31 | PRESTO researcher (PRESTO)
Employment
Source: Self-asserted source
Kazuo Takayama

Osaka University: Suita, JP

2018-02-01 to 2020-02-29 | Assistant Professor (Graduate School of Pharmaceutical Sciences)
Employment
Source: Self-asserted source
Kazuo Takayama

Osaka University: Suita, Osaka, JP

2015-04-01 to 2017-01-31 | Specially Appointed Assistant Professor (Graduate School of Pharmaceutical Sciences)
Employment
Source: Self-asserted source
Kazuo Takayama

Education and qualifications (1)

Osaka University: Suita, Osaka, JP

2010-04-01 to 2015-03-25 | PhD (Graduate School of Pharmaceutical Sciences)
Education
Source: Self-asserted source
Kazuo Takayama

Funding (4)

Elucidation of mechanism of chronic intestinal inflammation at single-cell level using optogenetic technique

2018-04-01 to 2020-03-31 | Grant
Japan Society for the Promotion of Science (Tokyo, JP)
GRANT_NUMBER: 18H05033
Source: Self-asserted source
Kazuo Takayama via DimensionsWizard

Generation of zone-specific hepatocyte for study of liver injury and diseases

Source: Self-asserted source
Kazuo Takayama via DimensionsWizard

Generation of CYP3A4-expressing human ES/iPS cell-derived hepatocytes for drug screening

2015-08-28 to 2017-03-31 | Grant
Japan Society for the Promotion of Science (Tokyo, JP)
GRANT_NUMBER: 15H06365
Source: Self-asserted source
Kazuo Takayama via DimensionsWizard

ヒトES/iPS細胞から肝細胞への高効率分化誘導法の開発とその創薬応用

2013-04-01 to 2015-03-31 | Grant
Japan Society for the Promotion of Science (Tokyo, JP)
GRANT_NUMBER: 13J00448
Source: Self-asserted source
Kazuo Takayama via DimensionsWizard

Works (50 of 119)

Items per page:
Page 1 of 3

Endothelial ROBO4 suppresses PTGS2/COX-2 expression and inflammatory diseases.

Communications biology
2024-05 | Journal article
Contributors: Tanaka M; Shirakura K; Takayama Y; Μatsui M; Watanabe Y; Yamamoto T; Takahashi J; Tanaka S; Hino N; Doi T et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Longitudinal analysis of genomic mutations in SARS-CoV-2 isolates from persistent COVID-19 patient.

iScience
2024-03 | Journal article
Contributors: Futatsusako H; Hashimoto R; Yamamoto M; Ito J; Matsumura Y; Yoshifuji H; Shirakawa K; Takaori-Kondo A; Takayama K
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Micro-patterned culture of iPSC-derived alveolar and airway cells distinguishes SARS-CoV-2 variants.

Stem cell reports
2024-03 | Journal article
Contributors: Masui A; Hashimoto R; Matsumura Y; Yamamoto T; Nagao M; Noda T; Takayama K; Gotoh S
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

A general fluorescence off/on strategy for fluorogenic probes: Steric repulsion-induced twisted intramolecular charge transfer (sr-TICT).

Science advances
2024-02 | Journal article
Contributors: Hanaoka K; Ikeno T; Iwaki S; Deguchi S; Takayama K; Mizuguchi H; Tao F; Kojima N; Ohno H; Sasaki E et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Virological characteristics of the SARS-CoV-2 Omicron XBB.1.5 variant.

Nature communications
2024-02 | Journal article
Contributors: Tamura T; Irie T; Deguchi S; Yajima H; Tsuda M; Nasser H; Mizuma K; Plianchaisuk A; Suzuki S; Uriu K et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

SARS-CoV-2-induced disruption of a vascular bed in a microphysiological system caused by type-I interferon from bronchial organoids.

Lab on a chip
2024-01 | Journal article
Contributors: Fujimoto K; Kameda Y; Nagano Y; Deguchi S; Yamamoto T; Krol RP; Gee P; Matsumura Y; Okamoto T; Nagao M et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Virological characteristics of the SARS-CoV-2 BA.2.86 variant.

Cell host & microbe
2024-01 | Journal article
Contributors: Tamura T; Mizuma K; Nasser H; Deguchi S; Padilla-Blanco M; Oda Y; Uriu K; Tolentino JEM; Tsujino S; Suzuki R et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Complement factor D targeting protects endotheliopathy in organoid and monkey models of COVID-19.

Cell stem cell
2023-10 | Journal article
Contributors: Kawakami E; Saiki N; Yoneyama Y; Moriya C; Maezawa M; Kawamura S; Kinebuchi A; Kono T; Funata M; Sakoda A et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Multiple mutations of SARS-CoV-2 Omicron BA.2 variant orchestrate its virological characteristics.

Journal of virology
2023-10 | Journal article
Contributors: Kimura I; Yamasoba D; Nasser H; Ito H; Zahradnik J; Wu J; Fujita S; Uriu K; Sasaki J; Tamura T et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Pluripotent stem cell-based therapies and their path to the clinic.

Stem cell reports
2023-08 | Journal article
Contributors: Takayama K; Yamanaka S
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Comparative pathogenicity of SARS-CoV-2 Omicron subvariants including BA.1, BA.2, and BA.5.

Communications biology
2023-07 | Journal article
Contributors: Tamura T; Yamasoba D; Oda Y; Ito J; Kamasaki T; Nao N; Hashimoto R; Fujioka Y; Suzuki R; Wang L et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Virological characterization of the 2022 outbreak-causing monkeypox virus using human keratinocytes and colon organoids.

Journal of medical virology
2023-06 | Journal article
Contributors: Watanabe Y; Kimura I; Hashimoto R; Sakamoto A; Yasuhara N; Yamamoto T; Genotype to Phenotype Japan (G2P-Japan) Consortium; Sato K; Takayama K
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Convergent evolution of SARS-CoV-2 Omicron subvariants leading to the emergence of BQ.1.1 variant.

Nature communications
2023-05 | Journal article
Contributors: Ito J; Suzuki R; Uriu K; Itakura Y; Zahradnik J; Kimura KT; Deguchi S; Wang L; Lytras S; Tamura T et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Organ-on-a-chip models for elucidating the cellular biology of infectious diseases.

Biochimica et biophysica acta. Molecular cell research
2023-05 | Journal article
Contributors: Yokoi F; Deguchi S; Takayama K
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants.

Nature communications
2023-05 | Journal article
Contributors: Tamura T; Ito J; Uriu K; Zahradnik J; Kida I; Anraku Y; Nasser H; Shofa M; Oda Y; Lytras S et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Elucidation of the liver pathophysiology of COVID-19 patients using liver-on-a-chips.

PNAS nexus
2023-03 | Journal article
Contributors: Deguchi S; Kosugi K; Hashimoto R; Sakamoto A; Yamamoto M; Krol RP; Gee P; Negoro R; Noda T; Yamamoto T et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Evaluation of Broad Anti-Coronavirus Activity of Autophagy-Related Compounds Using Human Airway Organoids.

Molecular pharmaceutics
2023-03 | Journal article
Contributors: Hashimoto R; Tamura T; Watanabe Y; Sakamoto A; Yasuhara N; Ito H; Nakano M; Fuse H; Ohta A; Noda T et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

[State-of-the-art in respiratory disease research using respiratory organoids].

Nihon yakurigaku zasshi. Folia pharmacologica Japonica
2023-01 | Journal article
Contributors: Deguchi S; Takayama K
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Design of a chimeric ACE-2/Fc-silent fusion protein with ultrahigh affinity and neutralizing capacity for SARS-CoV-2 variants.

Antibody therapeutics
2023-01 | Journal article
Contributors: Bodie NM; Hashimoto R; Connolly D; Chu J; Takayama K; Uhal BD
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Gene Therapy for Neuropsychiatric Disorders: Potential Targets and Tools.

CNS & neurological disorders drug targets
2023-01 | Journal article
Contributors: Shahcheraghi SH; Ayatollahi J; Lotfi M; Aljabali AAA; Al-Zoubi MS; Panda PK; Mishra V; Satija S; Charbe NB; Serrano-Aroca Á et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models.

Proceedings of the National Academy of Sciences of the United States of America
2023-01 | Journal article
Contributors: Morita M; Yoneda A; Tokunoh N; Masaki T; Shirakura K; Kinoshita M; Hashimoto R; Shigesada N; Takahashi J; Tachibana M et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

State-of-the-art liver disease research using liver-on-a-chip.

Inflammation and regeneration
2022-12 | Journal article
Contributors: Deguchi S; Takayama K
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Exocyst complex component 2 is a potential host factor for SARS-CoV-2 infection.

iScience
2022-10 | Journal article
Contributors: Yi R; Hashimoto R; Sakamoto A; Matsumura Y; Nagao M; Takahashi K; Takayama K
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Virological characteristics of the SARS-CoV-2 Omicron BA.2.75 variant.

Cell host & microbe
2022-10 | Journal article
Contributors: Saito A; Tamura T; Zahradnik J; Deguchi S; Tabata K; Anraku Y; Kimura I; Ito J; Yamasoba D; Nasser H et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Application of perfluoropolyether elastomers in microfluidic drug metabolism assays.

International journal of pharmaceutics
2022-09 | Journal article
Contributors: Wang M; Tsuda M; Deguchi S; Higuchi Y; So K; Torisawa YS; Takayama K; Yamashita F
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Non-uniform aspects of the SARS-CoV-2 intraspecies evolution reopen question of its origin.

International journal of biological macromolecules
2022-09 | Journal article
Contributors: Hassan SS; Kodakandla V; Redwan EM; Lundstrom K; Choudhury PP; Serrano-Aroca Á; Azad GK; Aljabali AAA; Palu G; Abd El-Aziz TM et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression.

Science advances
2022-09 | Journal article
Contributors: Hashimoto R; Takahashi J; Shirakura K; Funatsu R; Kosugi K; Deguchi S; Yamamoto M; Tsunoda Y; Morita M; Muraoka K et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Cell response analysis in SARS-CoV-2 infected bronchial organoids.

Communications biology
2022-05 | Journal article
Contributors: Sano E; Suzuki T; Hashimoto R; Itoh Y; Sakamoto A; Sakai Y; Saito A; Okuzaki D; Motooka D; Muramoto Y et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Generation of HepG2 Cells with High Expression of Multiple Drug-Metabolizing Enzymes for Drug Discovery Research Using a PITCh System

Cells
2022-05 | Journal article | Author
Contributors: Ryosuke Negoro; Mitsuki Tasaka; Sayaka Deguchi; Kazuo Takayama; Takuya Fujita
Source: check_circle
Multidisciplinary Digital Publishing Institute

Biocompatible Films of Calcium Alginate Inactivate Enveloped Viruses Such as SARS-CoV-2

Polymers
2022-04 | Journal article | Author
Contributors: Alba Cano-Vicent; Rina Hashimoto; Kazuo Takayama; Ángel Serrano-Aroca
Source: check_circle
Multidisciplinary Digital Publishing Institute

Decellularized Organ-Derived Scaffold Is a Promising Carrier for Human Induced Pluripotent Stem Cells-Derived Hepatocytes.

Cells
2022-04 | Journal article
Contributors: Kojima H; Yagi H; Kushige H; Toda Y; Takayama K; Masuda S; Morisaku T; Tsuchida T; Kuroda K; Hirukawa K et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Would New SARS-CoV-2 Variants Change the War against COVID-19?

Epidemiologia
2022-04 | Journal article | Author
Contributors: Elrashdy Moustafa Mohamed Redwan, Elrashdy M M Redwan, El-Rashdy M Mohamed, El Rashdy Mohamed; Fatma Elrashdy; Alaa A. A. Aljabali; Wagner Baetas-da-Cruz; Debmalya Barh; Adam Brufsky; Sk Sarif Hassan; Kenneth Lundstrom; Ángel Serrano-Aroca; Kazuo Takayama et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

An issue of concern: unique truncated ORF8 protein variants of SARS-CoV-2.

PeerJ
2022-03 | Journal article
Contributors: Hassan SS; Kodakandla V; Redwan EM; Lundstrom K; Pal Choudhury P; Abd El-Aziz TM; Takayama K; Kandimalla R; Lal A; Serrano-Aroca Á et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Establishment of a stable SARS-CoV-2 replicon system for application in high-throughput screening.

Antiviral research
2022-03 | Journal article
Contributors: Tanaka T; Saito A; Suzuki T; Miyamoto Y; Takayama K; Okamoto T; Moriishi K
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Intestinal Permeability of Drugs in Caco-2 Cells Cultured in Microfluidic Devices.

Biological & pharmaceutical bulletin
2022-01 | Journal article
Contributors: Sasaki Y; Tatsuoka H; Tsuda M; Sumi T; Eguchi Y; So K; Higuchi Y; Takayama K; Torisawa Y; Yamashita F
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

SARS-CoV-2 infection triggers paracrine senescence and leads to a sustained senescence-associated inflammatory response.

Nature aging
2022-01 | Journal article
Contributors: Tsuji S; Minami S; Hashimoto R; Konishi Y; Suzuki T; Kondo T; Sasai M; Torii S; Ono C; Shichinohe S et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

The importance of accessory protein variants in the pathogenicity of SARS-CoV-2.

Archives of biochemistry and biophysics
2022-01 | Journal article
Contributors: Hassan SS; Choudhury PP; Dayhoff GW; Aljabali AAA; Uhal BD; Lundstrom K; Rezaei N; Pizzol D; Adadi P; Lal A et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Therapeutic Potential of Cannabinoids on Tumor Microenvironment: A Molecular Switch in Neoplasia Transformation.

Integrative cancer therapies
2022-01 | Journal article
Contributors: Bakshi HA; Faruck HL; Ravesh Z; Ansari P; Hannan JMA; Hashimoto R; Takayama K; Farzand R; Nasef MM; Mensah A et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Emergence of unique SARS-CoV-2 ORF10 variants and their impact on protein structure and function.

International journal of biological macromolecules
2021-12 | Journal article
Contributors: Hassan SS; Lundstrom K; Serrano-Aroca Á; Adadi P; Aljabali AAA; Redwan EM; Lal A; Kandimalla R; El-Aziz TMA; Pal Choudhury P et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Non-Woven Infection Prevention Fabrics Coated with Biobased Cranberry Extracts Inactivate Enveloped Viruses Such as SARS-CoV-2 and Multidrug-Resistant Bacteria

International Journal of Molecular Sciences
2021-11 | Journal article | Author
Contributors: Kazuo Takayama; Alberto Tuñón Molina; Alba Cano-Vicent; Yukiko MURAMOTO; Takeshi Noda; Jose Luis Aparicio-Collado; Roser Sabater i Serra; Miguel Martí; Ángel Serrano-Aroca
Source: check_circle
Multidisciplinary Digital Publishing Institute

Protective Face Masks: Current Status and Future Trends.

ACS applied materials & interfaces
2021-11 | Journal article
Contributors: Tuñón-Molina A; Takayama K; Redwan EM; Uversky VN; Andrés J; Serrano-Aroca Á
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Dual inhibition of TMPRSS2 and Cathepsin Bprevents SARS-CoV-2 infection in iPS cells.

Molecular therapy. Nucleic acids
2021-10 | Journal article
Contributors: Hashimoto R; Sakamoto A; Deguchi S; Yi R; Sano E; Hotta A; Takahashi K; Yamanaka S; Takayama K
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Antimicrobial Face Shield: Next Generation of Facial Protective Equipment against SARS-CoV-2 and Multidrug-Resistant Bacteria

International Journal of Molecular Sciences
2021-09 | Journal article | Author
Contributors: Alberto Tuñón Molina; Miguel Martí; Yukiko MURAMOTO; Takeshi Noda; Kazuo Takayama; Ángel Serrano-Aroca
Source: check_circle
Multidisciplinary Digital Publishing Institute

Antiviral Face Mask Functionalized with Solidified Hand Soap: Low-Cost Infection Prevention Clothing against Enveloped Viruses Such as SARS-CoV-2.

ACS omega
2021-09 | Journal article
Contributors: Cano-Vicent A; Tuñón-Molina A; Martí M; Muramoto Y; Noda T; Takayama K; Serrano-Aroca Á
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Autoimmunity roots of the thrombotic events after COVID-19 vaccination.

Autoimmunity reviews
2021-09 | Journal article
Contributors: Elrashdy F; Tambuwala MM; Hassan SS; Adadi P; Seyran M; Abd El-Aziz TM; Rezaei N; Lal A; Aljabali AAA; Kandimalla R et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Generation of Tetrafluoroethylene-Propylene Elastomer-Based Microfluidic Devices for Drug Toxicity and Metabolism Studies.

ACS omega
2021-09 | Journal article
Contributors: Sano E; Deguchi S; Matsuoka N; Tsuda M; Wang M; Kosugi K; Mori C; Yagi K; Wada A; Yamasaki S et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Implications derived from S-protein variants of SARS-CoV-2 from six continents.

International journal of biological macromolecules
2021-09 | Journal article
Contributors: Hassan SS; Lundstrom K; Barh D; Silva RJS; Andrade BS; Azevedo V; Choudhury PP; Palu G; Uhal BD; Kandimalla R et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Periodically aperiodic pattern of SARS-CoV-2 mutations underpins the uncertainty of its origin and evolution.

Environmental research
2021-09 | Journal article
Contributors: Hassan SS; Basu P; Redwan EM; Lundstrom K; Choudhury PP; Serrano-Aroca A; Azad GK; Aljabali AAA; Palu G; El-Aziz TMA et al.
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central

Potential Molecular Mechanisms of Rare Anti-Tumor Immune Response by SARS-CoV-2 in Isolated Cases of Lymphomas

Viruses
2021-09 | Journal article | Author
Contributors: Debmalya Barh; Sandeep Tiwari; Lucas Gabriel Rodrigues Gomes; Marianna Weener; Khalid J. Alzahrani; Khalaf Alsharif; Alaa A. A. Aljabali; Murtaza M. Tambuwala; Kenneth Lundstrom; Sk. Sarif Hassan et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

Clinical utility of novel biosensing platform: Diagnosis of coronavirus SARS-CoV-2 at point of care.

Materials letters
2021-08 | Journal article
Contributors: Aljabali AAA; Pal K; Serrano-Aroca A; Takayama K; Dua K; Tambuwala MM
Source: Self-asserted source
Kazuo Takayama via Europe PubMed Central
Items per page:
Page 1 of 3

Peer review (38 reviews for 24 publications/grants)

Review activity for Accounts of chemical research. (1)
Review activity for ACS applied materials & interfaces. (3)
Review activity for ACS omega. (2)
Review activity for Advanced healthcare materials (2)
Review activity for Bio-Design and Manufacturing (1)
Review activity for Cell biology and toxicology. (1)
Review activity for Cell metabolism. (1)
Review activity for Communications biology. (3)
Review activity for EBioMedicine. (2)
Review activity for European journal of cell biology. (2)
Review activity for In vitro models. (2)
Review activity for Inflammation and regeneration. (2)
Review activity for iScience. (3)
Review activity for Journal of infectious diseases. (1)
Review activity for Molecular and cellular endocrinology. (1)
Review activity for Molecular pharmaceutics. (1)
Review activity for Molecular therapy. (1)
Review activity for Nature biotechnology. (1)
Review activity for Nature communications (2)
Review activity for NPG Asia materials. (1)
Review activity for npj regenerative medicine. (1)
Review activity for PloS one. (1)
Review activity for Signal transduction and targeted therapy. (1)
Review activity for Toxicology in vitro. (2)