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Other IDs

Loop profile: 1564310

Keywords

Protein synthesis, ribosome synthesis, RNA metabolism, protein expression, protein structure

Countries

Brazil

Activities

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Employment (4)

Oswaldo Cruz Foundation: Curitiba, Paraná, BR

2012-05-29 to present | Research Scientist (Carlos Chagas Institue)
Employment
Source: Self-asserted source
Nilson Zanchin

Centro Nacional de Pesquisa em Energia e Materiais: Campinas, SP, BR

2000-01-02 to 2010-07-31 | Research Scientist (Center for Structural Molecular Biology)
Employment
Source: Self-asserted source
Nilson Zanchin

Universidade de São Paulo: Sao Paulo, SP, BR

1998-10-01 to 1999-12-31 | Postdoctoral fellow (Biochemistry)
Employment
Source: Self-asserted source
Nilson Zanchin

University of Rochester: Rochester, NY, US

1995-09-01 to 1998-08-30 | Postdoctoral fellow (Biology)
Employment
Source: Self-asserted source
Nilson Zanchin

Education and qualifications (4)

Helmholtz-Zentrum für Infektionsforschung GmbH: Braunschweig, Niedersachsen, DE

1991-01-01 to 1995-07-17 | PhD Student
Education
Source: Self-asserted source
Nilson Zanchin

Federal University of Rio Grande do Sul: Porto Alegre, Rio Grande do Sul, BR

1988-08-01 to 1990-12-31 | Molecular Biology training (Center of Biotechnology)
Qualification
Source: Self-asserted source
Nilson Zanchin

Federal University of Rio Grande do Sul: Porto Alegre, Rio Grande do Sul, BR

1986-03-01 to 1988-07-31 | MSc Student (Genetics)
Qualification
Source: Self-asserted source
Nilson Zanchin

Federal University of Rio Grande do Sul: Porto Alegre, Rio Grande do Sul, BR

1982-03-01 to 1985-12-31 | Undergraduate Student - Biology (Biology)
Qualification
Source: Self-asserted source
Nilson Zanchin

Works (50 of 92)

Items per page:
Page 1 of 2

Trypanosoma cruzi eIF4E3- and eIF4E4-containing complexes bind different mRNAs and may sequester inactive mRNAs during nutritional stress

Nucleic Acids Research
2025-01-11 | Journal article
DOI: 10.1093/nar/gkae1181
Contributors: Bernardo Papini Gabiatti; Eden Ribeiro Freire; Jimena Ferreira da Costa; Mariana Galvão Ferrarini; Tatiana Reichert Assunção de Matos; Henrique Preti; Isadora Munhoz da Rocha; Beatriz Gomes Guimarães; Susanne Kramer; Nilson Ivo Tonin Zanchin et al.
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Crossref

Two distinctTrypanosomaeIF4F complexes co-exist, bind different mRNAs and are regulated during nutritional stress

2024-04-15 | Preprint
DOI: 10.1101/2024.04.15.589194
Contributors: Bernardo Papini Gabiatti; Eden Ribeiro Freire; Jimena Ferreira da Costa; Mariana Galvão Ferrarini; Tatiana Reichert Assunção de Matos; Henrique Preti; Isadora Munhoz da Rocha; Beatriz Gomes Guimarães; Susanne Kramer; Nilson Ivo Tonin Zanchin et al.
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Crossref

Structural analysis of the Trypanosoma brucei EIF4E6/EIF4G5 complex reveals details of the interaction between unusual eIF4F subunits

Scientific Reports
2024-01-25 | Journal article
DOI: 10.1038/s41598-024-52364-1
Part of ISSN: 2045-2322
Contributors: Renato Ferras Penteado; Renata Santana da Silva; Danielle Maria Nascimento Moura; Gustavo Barbosa de Lima; Amaranta Muniz Malvezzi; Tallyta Tâmara da Silva Monteiro; Camila Cavalcanti Xavier; Sophie Vichier-Guerre; Laurence Dugué; Sylvie Pochet et al.
Source: Self-asserted source
Nilson Zanchin

Seroepidemiological Survey of Chronic Chagas Disease in a Rural Community in Southern Bahia, Brazil, Using Recombinant Chimeric Antigens

Pathogens
2023-10 | Journal article | Author
DOI: 10.3390/pathogens12101222
Contributors: Neci Matos Soares; Nilo Manoel Pereira Vieira Barreto; Marina Morena Brito Farias; Cíntia de Lima Oliveira; Weslei Almeida Costa Araújo; de Souza, JN; Márcia Cristina Aquino Teixeira; Noilson Lázaro Sousa Gonçalves; Daniel Dias Sampaio; Tycha Bianca Sabaini Pavan et al.
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Multidisciplinary Digital Publishing Institute

Development of an anti‐SARS‐CoV‐2 monoclonal antibody panel and its applicability as a reagent in high‐throughput fluorescence reduction neutralization and immunohistochemistry assays

Journal of Medical Virology
2023-09 | Journal article
DOI: 10.1002/jmv.29111
Contributors: Gabriela M. Coelho; Allan H. D. Cataneo; Sonia M. Raboni; Meri B. Nogueira; Caroline B. Vaz de Paula; Ana C. S. F. Almeida; Vanessa Z. Rogerio; Nilson T. Zanchin; Lucia de Noronha; Camila Zanluca et al.
Source: check_circle
Crossref

In cellulo and in vivo assays for compound testing against Trypanosoma cruzi

STAR Protocols
2023-03 | Journal article
DOI: 10.1016/j.xpro.2023.102058
Contributors: Eloise Pavão Guerra-Slompo; Gisele Fernanda Assine Picchi-Constante; Martin Marek; Christophe Romier; Wolfgang Sippl; Nilson Ivo Tonin Zanchin
Source: check_circle
Crossref

Dissecting Trypanosoma brucei RRP44 function in the maturation of segmented ribosomal RNA using a regulated genetic complementation system

Nucleic Acids Research
2023-01-11 | Journal article
DOI: 10.1093/nar/gkac1217
Contributors: Eloise Pavão Guerra-Slompo; Giovanna Cesaro; Beatriz Gomes Guimarães; Nilson Ivo Tonin Zanchin
Source: check_circle
Crossref

Trypanosoma brucei RRP44: a versatile enzyme for processing structured and non-structured RNA substrates

Nucleic Acids Research
2023-01-11 | Journal article
DOI: 10.1093/nar/gkac1199
Contributors: Giovanna Cesaro; Heloisa Tramontin da Soler; Eloise Pavão Guerra-Slompo; Ahmed Haouz; Pierre Legrand; Nilson Ivo Tonin Zanchin; Beatriz Gomes Guimaraes
Source: check_circle
Crossref

Functional EGF domain of the human neuregulin 1α produced in Escherichia coli with accurate disulfide bonds

Molecular Biology Reports
2022-12 | Journal article
DOI: 10.1007/s11033-022-07956-3
Contributors: Arthur Schveitzer Ferreira; Amanda Lopacinski; Michel Batista; Priscila Mazzocchi Hiraiwa; Natalia Fernanda Bueno; Beatriz Gomes Guimarães; Nilson I. T. Zanchin
Source: check_circle
Crossref

Efficient CRISPR-Cas9-mediated genome editing for characterization of essential genes in Trypanosoma cruzi

STAR Protocols
2022-06 | Journal article
DOI: 10.1016/j.xpro.2022.101324
Contributors: Gisele Fernanda Assine Picchi-Constante; Priscila Mazzocchi Hiraiwa; Martin Marek; Vanessa Zulkievicz Rogerio; Eloise Pavão Guerra-Slompo; Christophe Romier; Nilson Ivo Tonin Zanchin
Source: check_circle
Crossref

The translation initiation factor EIF4E5 from Leishmania: crystal structure and interacting partners

RNA Biology
2021-12-02 | Journal article
DOI: 10.1080/15476286.2021.1918919
Contributors: Gustavo Barbosa de Lima; Thaíse Yasmine Vasconcelos de Lima Cavalcanti; Adriana Neuman Albuquerque Lins Moura de Brito; Ludmilla Arruda de Assis; Rafaela Paiva Andrade-Vieira; Eden Ribeiro Freire; Tatiana Reichert da Silva Assunção; Christian Robson de Souza Reis; Nilson Ivo Tonin Zanchin; Beatriz Gomes Guimarães et al.
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Crossref

Assessment of Liaison XL Murex Chagas diagnostic performance in blood screening for Chagas disease using a reference array of chimeric antigens

Transfusion
2021-09 | Journal article
DOI: 10.1111/trf.16583
Contributors: Emily F. Santos; Leonardo M. Leony; Ângelo A. O. Silva; Ramona T. Daltro; Natália E. M. Freitas; Larissa C. M. Vasconcelos; Fernando L. V. de Araújo; Paola A. F. Celedon; Marco A. Krieger; Nilson I. T. Zanchin et al.
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Crossref

Stability Assessment of Four Chimeric Proteins for Human Chagas Disease Immunodiagnosis

Biosensors
2021-08-22 | Journal article
DOI: 10.3390/bios11080289
Contributors: Paola Alejandra Fiorani Celedon; Leonardo Maia Leony; Ueriton Dias Oliveira; Natália Erdens Maron Freitas; Ângelo Antônio Oliveira Silva; Ramona Tavares Daltro; Emily Ferreira Santos; Marco Aurélio Krieger; Nilson Ivo Tonin Zanchin; Fred Luciano Neves Santos
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

The impact of blood-processing time on the proteome of human peripheral blood mononuclear cells

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
2021-03 | Journal article
DOI: 10.1016/j.bbapap.2020.140581
Part of ISSN: 1570-9639
Source: Self-asserted source
Nilson Zanchin

Novel Genetic Constructs for Production of Recombinant HTLV-1/2 Antigens and Evaluation of Their Reactivity to Plasma Samples from HTLV-1-Infected Patients

Journal of Clinical Microbiology
2021-03-19 | Journal article
DOI: 10.1128/JCM.02701-20
Contributors: Ueriton Dias de Oliveira; Fred Luciano Neves Santos; Bernardo Galvão-Castro; Marco Aurelio Krieger; Nilson Ivo Tonin Zanchin; Yi-Wei Tang
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Crossref

Synthetic fish metallothionein design as a potential tool for monitoring toxic metals in water

Environmental Science and Pollution Research
2020-11-04 | Journal article
DOI: 10.1007/s11356-020-11427-2
Part of ISSN: 0944-1344
Part of ISSN: 1614-7499
Source: Self-asserted source
Nilson Zanchin

Development of a New Lateral Flow Assay Based on IBMP-8.1 and IBMP-8.4 Chimeric Antigens to Diagnose Chagas Disease

BioMed Research International
2020-08-18 | Journal article
DOI: 10.1155/2020/1803515
Part of ISSN: 2314-6133
Part of ISSN: 2314-6141
Source: Self-asserted source
Nilson Zanchin

Performance of Treponema pallidum recombinant proteins in the serological diagnosis of syphilis.

PloS one
2020-06-18 | Journal article
DOI: 10.1371/journal.pone.0234043
PMID: 32555593
PMC: PMC7302711
Source: Self-asserted source
Nilson Zanchin

Identification of the major allergenic proteins from silkworm moth (Bombyx mori) involved in respiratory allergic diseases.

Allergologia et immunopathologia
2020-04-10 | Journal article
DOI: 10.1016/j.aller.2019.12.003
PMID: 32284266
Source: Self-asserted source
Nilson Zanchin

Immune reactivity to Trypanosoma cruzi chimeric proteins for Chagas disease diagnosis in immigrants living in a non-endemic setting

BMC Infectious Diseases
2019-12 | Journal article
DOI: 10.1186/s12879-019-3872-z
Part of ISSN: 1471-2334
Source: Self-asserted source
Nilson Zanchin

Crystal structure of the MIF4G domain of the Trypanosoma cruzi translation initiation factor EIF4G5.

Acta crystallographica. Section F, Structural biology communications
2019-11-20 | Journal article
DOI: 10.1107/s2053230x19015061
PMID: 31797815
PMC: PMC6891579
Source: Self-asserted source
Nilson Zanchin

Performance of recombinant chimeric proteins in the serological diagnosis of Trypanosoma cruzi infection in dogs

PLOS Neglected Tropical Diseases
2019-06-26 | Journal article
DOI: 10.1371/journal.pntd.0007545
Part of ISSN: 1935-2735
Source: Self-asserted source
Nilson Zanchin
grade
Preferred source (of 2)‎

Crystal structure of the Trypanosoma cruzi EIF4E5 translation factor homologue in complex with mRNA cap-4

Nucleic Acids Research
2019-06-20 | Journal article
DOI: 10.1093/nar/gkz339
Part of ISSN: 0305-1048
Part of ISSN: 1362-4962
Source: Self-asserted source
Nilson Zanchin

Cross-Reactivity Using Chimeric Trypanosoma cruzi Antigens: Diagnostic Performance in Settings Where Chagas Disease and American Cutaneous or Visceral Leishmaniasis Are Coendemic

Journal of Clinical Microbiology
2019-06-12 | Journal article
DOI: 10.1128/jcm.00762-19
Part of ISSN: 0095-1137
Part of ISSN: 1098-660X
Source: Self-asserted source
Nilson Zanchin

Genotype Variation in Rice (Oryza sativa L.) Tolerance to Fe Toxicity Might Be Linked to Root Cell Wall Lignification

Frontiers in Plant Science
2019-06-12 | Journal article
DOI: 10.3389/fpls.2019.00746
Part of ISSN: 1664-462X
Source: Self-asserted source
Nilson Zanchin

Interactome analysis of the human Cap‐specific mRNA (nucleoside‐2′‐O‐)‐methyltransferase 1 (hMTr1) protein

Journal of Cellular Biochemistry
2019-04 | Journal article
DOI: 10.1002/jcb.27843
Contributors: Fernando Moreira Simabuco; Isadora Carolina Betim Pavan; Nathalie Fortes Pestana; Paulo Costa Carvalho; Fernanda Luisa Basei; Daniela Campos Granato; Adriana Franco Paes Leme; Nilson Ivo Tonin Zanchin
Source: check_circle
Crossref

Detection of anti-Trypanosoma cruzi antibodies by chimeric antigens in chronic Chagas disease-individuals from endemic South American countries

PLOS ONE
2019-04-18 | Journal article
DOI: 10.1371/journal.pone.0215623
Part of ISSN: 1932-6203
Source: Self-asserted source
Nilson Zanchin

Trypanosoma brucei RRP44 is involved in an early stage of large ribosomal subunit RNA maturation

RNA Biology
2019-01-02 | Journal article
DOI: 10.1080/15476286.2018.1564463
Part of ISSN: 1547-6286
Part of ISSN: 1555-8584
Source: Self-asserted source
Nilson Zanchin
grade
Preferred source (of 2)‎

The Leishmania PABP1-eIF4E4 interface: a novel 5'-3' interaction architecture for trans-spliced mRNAs.

Nucleic Acids Research
2018-11-22 | Journal article
DOI: 10.1093/nar/gky1187
Source: Self-asserted source
Nilson Zanchin
grade
Preferred source (of 2)‎

L-Asparaginase from Erwinia carotovora: insights about its stability and activity.

Molecular Biology Reports
2018-11-16 | Journal article
DOI: 10.1007/s11033-018-4459-2
Source: Self-asserted source
Nilson Zanchin

High accuracy of an ELISA test based in a flagella antigen of Leishmania in serodiagnosis of canine visceral leishmaniasis with potential to improve the control measures in Brazil – A Phase II study

PLOS Neglected Tropical Diseases
2018-10-26 | Journal article
DOI: 10.1371/journal.pntd.0006871
Part of ISSN: 1935-2735
Source: Self-asserted source
Nilson Zanchin

Highly Accurate Chimeric Proteins for the Serological Diagnosis of Chronic Chagas Disease: A Latent Class Analysis.

The American journal of tropical medicine and hygiene
2018-09 | Journal article
DOI: 10.4269/ajtmh.17-0727
PMID: 30226130
Contributors: Santos FLN; Campos ACP; Amorim LDAF; da Silva ED; Zanchin NIT; Celedon PAF; Del-Rei RP; Krieger MA; Gomes YM
Source: Self-asserted source
Nilson Zanchin via Europe PubMed Central

Investigation of CAV1/CAV2 rs4236601 and CDKN2B-AS1 rs2157719 in primary open-angle glaucoma patients from Brazil.

Ophthalmic genetics
2017-11 | Journal article
DOI: 10.1080/13816810.2017.1393830
PMID: 29111846
Contributors: Nunes HF; Ananina G; Costa VP; Zanchin NIT; de Vasconcellos JPC; de Melo MB
Source: Self-asserted source
Nilson Zanchin via Europe PubMed Central

In silico analysis of amino acid variation in human respiratory syncytial virus: insights into immunodiagnostics.

Memórias do Instituto Oswaldo Cruz
2017-10 | Journal article
DOI: 10.1590/0074-02760170013
PMID: 28953993
PMC: PMC5607514
Contributors: Souza C; Zanchin NI; Krieger MA; Ludwig A
Source: Self-asserted source
Nilson Zanchin via Europe PubMed Central

InP Nanowire Biosensor with Tailored Biofunctionalization: Ultrasensitive and Highly Selective Disease Biomarker Detection.

Nano letters
2017-09 | Journal article
DOI: 10.1021/acs.nanolett.7b01803
PMID: 28895736
Contributors: Janissen R; Sahoo PK; Santos CA; da Silva AM; von Zuben AAG; Souto DEP; Costa ADT; Celedon P; Zanchin NIT; Almeida DB et al.
Source: Self-asserted source
Nilson Zanchin via Europe PubMed Central

Performance Assessment of a Trypanosoma cruzi Chimeric Antigen in Multiplex Liquid Microarray Assays.

Journal of clinical microbiology
2017-07 | Journal article
DOI: 10.1128/JCM.00851-17
PMID: 28724556
PMC: PMC5625379
Contributors: Santos FLN; Celedon PAF; Zanchin NIT; Leitolis A; Crestani S; Foti L; de Souza WV; Gomes YM; Krieger MA
Source: Self-asserted source
Nilson Zanchin via Europe PubMed Central

ABI3, a component of the WAVE2 complex, is potentially regulated by PI3K/AKT pathway.

Oncotarget
2017-06 | Journal article
DOI: 10.18632/oncotarget.18840
PMID: 28978070
PMC: PMC5620210
Contributors: Moraes L; Zanchin NIT; Cerutti JM
Source: Self-asserted source
Nilson Zanchin via Europe PubMed Central

Accuracy of chimeric proteins in the serological diagnosis of chronic chagas disease - a Phase II study.

PLoS neglected tropical diseases
2017-03 | Journal article
DOI: 10.1371/journal.pntd.0005433
PMID: 28273127
PMC: PMC5358787
Contributors: Santos FL; Celedon PA; Zanchin NI; de Souza WV; da Silva ED; Foti L; Krieger MA; Gomes YM
Source: Self-asserted source
Nilson Zanchin via Europe PubMed Central

Post-translational Modifications of Trypanosoma cruzi Canonical and Variant Histones.

Journal of proteome research
2017-01 | Journal article
DOI: 10.1021/acs.jproteome.6b00655
PMID: 28076955
Contributors: Picchi GF; Zulkievicz V; Krieger MA; Zanchin NT; Goldenberg S; de Godoy LM
Source: Self-asserted source
Nilson Zanchin via Europe PubMed Central

A Time-Based and Intratumoral Proteomic Assessment of a Recurrent Glioblastoma Multiforme.

Frontiers in Oncology
2016-08 | Journal article
DOI: 10.3389/fonc.2016.00183
PMID: 27597932
PMC: PMC4992702
Contributors: de Aquino PF; Carvalho PC; Nogueira FC; da Fonseca CO; de Souza Silva JC; Carvalho Mda G; Domont GB; Zanchin NI; Fischer Jde S
Source: Self-asserted source
Nilson Zanchin via Europe PubMed Central

Crystal structure of the human Tip41 orthologue, TIPRL, reveals a novel fold and a binding site for the PP2Ac C-terminus.

Scientific reports
2016-08 | Journal article
DOI: 10.1038/srep30813
PMID: 27489114
PMC: PMC4973239
Contributors: Scorsato V; Lima TB; Righetto GL; Zanchin NI; Brandão-Neto J; Sandy J; Pereira HD; Ferrari ÁJ; Gozzo FC; Smetana JH et al.
Source: Self-asserted source
Nilson Zanchin via Europe PubMed Central

Performance Assessment of Four Chimeric Trypanosoma cruzi Antigens Based on Antigen-Antibody Detection for Diagnosis of Chronic Chagas Disease.

PloS one
2016-08 | Journal article
DOI: 10.1371/journal.pone.0161100
PMID: 27517281
PMC: PMC4982698
Contributors: Santos FL; Celedon PA; Zanchin NI; Brasil Tde A; Foti L; Souza WV; Silva ED; Gomes Yde M; Krieger MA
Source: Self-asserted source
Nilson Zanchin via Europe PubMed Central

Development of a magnetic separation method to capture sepsis associated bacteria in blood.

Journal of microbiological methods
2016-07 | Journal article
DOI: 10.1016/j.mimet.2016.07.012
PMID: 27432342
Contributors: Lopes ALK; Cardoso J; Dos Santos FRCC; Silva ACG; Stets MI; Zanchin NIT; Soares MJ; Krieger MA
Source: Self-asserted source
Nilson Zanchin via Europe PubMed Central

Identification of potential targets for an anticoagulant pectin.

Journal of proteomics
2016-06 | Journal article
DOI: 10.1016/j.jprot.2016.06.013
PMID: 27318178
Contributors: Santana AG; Gracher AH; Rüdiger AL; Zanchin NI; Carvalho PC; Cipriani TR; de Arruda Campos Brasil de Souza T
Source: Self-asserted source
Nilson Zanchin via Europe PubMed Central

Single point mutations in the helicase domain of the NS3 protein enhance dengue virus replicative capacity in human monocyte-derived dendritic cells and circumvent the type I interferon response.

Clinical and experimental immunology
2015-10 | Journal article
DOI: 10.1111/cei.12701
PMID: 26340409
Contributors: Silveira GF; Strottmann DM; de Borba L; Mansur DS; Zanchin NI; Bordignon J; dos Santos CN
Source: Self-asserted source
Nilson Zanchin via Europe PubMed Central

PI3K inhibition synergizes with glucocorticoids but antagonizes with methotrexate in T-cell acute lymphoblastic leukemia.

Oncotarget
2015-05 | Journal article
DOI: 10.18632/oncotarget.3524
PMID: 25869207
PMC: PMC4537002
Contributors: Silveira AB; Laranjeira AB; Rodrigues GO; Leal PC; Cardoso BA; Barata JT; Yunes RA; Zanchin NI; Brandalise SR; Yunes JA
Source: Self-asserted source
Nilson Zanchin via Europe PubMed Central

A scoring model for phosphopeptide site localization and its impact on the question of whether to use MSA.

Journal of proteomics
2015-01 | Journal article
DOI: 10.1016/j.jprot.2015.01.008
PMID: 25623781
Contributors: Fischer JSDG; Dos Santos MDM; Marchini FK; Barbosa VC; Carvalho PC; Zanchin NIT
Source: Self-asserted source
Nilson Zanchin via Europe PubMed Central

Active ingredients against human epidermal aging.

Ageing research reviews
2014-03 | Journal article
DOI: 10.1016/j.arr.2014.03.002
PMID: 24675046
Contributors: Lorencini M; Brohem CA; Dieamant GC; Zanchin NI; Maibach HI
Source: Self-asserted source
Nilson Zanchin via Europe PubMed Central

Pinpointing differentially expressed domains in complex protein mixtures with the cloud service of PatternLab for Proteomics.

Journal of proteomics
2013-06 | Journal article
DOI: 10.1016/j.jprot.2013.06.013
PMID: 23796493
Contributors: Leprevost FV; Lima DB; Crestani J; Perez-Riverol Y; Zanchin N; Barbosa VC; Carvalho PC
Source: Self-asserted source
Nilson Zanchin via Europe PubMed Central

Structural characterization of the internal transcribed spacer 2 (ITS2) of the ribosomal DNA (rDNA) cluster in Calyptratae (Diptera: Schizophora) and its implications for molecular phylogenetic analyses.

Journal of molecular evolution
2013-02 | Journal article
DOI: 10.1007/s00239-013-9548-1
PMID: 23420176
Contributors: Marinho MA; Azeredo-Espin AM; Zanchin NI
Source: Self-asserted source
Nilson Zanchin via Europe PubMed Central
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