Personal information

Drug-membrane interactions, SAXS, Liposomes, WAXS, Drug delivery systems
Portugal

Biography

2005 - Graduation in Physics and Chemistry in the Faculty of Sciences of Porto University.
2006 – European Master degree in Environmental Analytical Chemistry in the Pharmacy Faculty of Porto University.
2011 - PhD in Pharmaceutical Sciences – Pharmaceutical and Medicinal Chemistry in the Faculty of Pharmacy of Porto University.

At the time Cláudia Nunes has a FCT Investigator contract. Cláudia obtained this Starting Grant for her proposal named “Upgrading rheumatoid arthritis treatment through a targeted nanotherapeutic approach", in the Biophysics and Biomembranes Unit of the UCIBIO, REQUIMTE/ FFUP research center.
The main research activity is focused on membrane biophysics, more particularly in drug membrane interactions which involves drug pharmacological activity, selectivity and toxicity, moreover, in the physicochemical analytical methods for analyzing and quantifying various aspects of drug-membrane interactions. Derivative UV/vis. spectroscopy, fluorescence anisotropy, quenching and lifetime, X-ray scattering, infrared reflection absorption spectroscopy and atomic force microscopy are the major applied techniques. One of the other mainstreams of the investigation is the development of new nanotechnology based drug delivery systems that would be efficiently carried to the inflamed tissues avoiding the gastric local toxic effects of the classical therapies. Hence the work developed within this line of research aims to overcome the mentioned disadvantages of the current therapies, by the development of innovative nanosystems (silica nanotubes, solid lipid nanoparticles, nanostructured lipid particles and liposomes) for drug delivery.
At the time, Cláudia Nunes also belongs to the management commitee of a COST action: CA16124 - BIO-Brillouin Light (2017-2020).

Activities

Funding (16)

Eradicating bacterial BIOfilms from implants: a three step approach to dismantle the MATRIXome, planktonic bacteria and alpha toxins (BIOMATRIX)

2023-02-20 to 2029-02-19 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

2022.05608.CEECIND

GRANT_NUMBER:

2022.05608.CEECIND/CP1724/CT0002

Source: check_circle
CIÊNCIAVITAE

Honey-exosomes to fight superbugs

2022-01-01 to 2023-06-30 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

EXPL/NAN-MAT/0743/2021

Source: check_circle
CIÊNCIAVITAE

Associated Laboratory for Green Chemistry - Clean Technologies and Processes

2021-01-01 to 2025-12-31 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

LA/P/0008/2020

Source: check_circle
CIÊNCIAVITAE

Applied Molecular Biosciences Unit

2019-01-01 to 2019-12-31 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

UID/Multi/04378/2019

Source: check_circle
CIÊNCIAVITAE

Associated Laboratory for Green Chemistry - Clean Technologies and Processes

2019-01-01 to 2019-12-31 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

UID/QUI/50006/2019

Source: check_circle
CIÊNCIAVITAE

3Ds - Administração Transdérmica de Fármacos

2018-07-01 to 2021-12-31 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/QUI-COL/30834/2017

Source: check_circle
CIÊNCIAVITAE

Uma abordagem nanotecnológica, seletiva e direcionada para evitar a remoção cirúrgica de implantes infectados por biofilmes

2018-07-01 to 2021-12-31 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/NAN-MAT/31444/2017

Source: check_circle
CIÊNCIAVITAE

Upgrading rheumatoid arthritis treatment through a targeted nanotherapeutic approach

2017-01-01 to 2021-12-31 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

IF/00293/2015/CP1279/CT0003

Source: check_circle
CIÊNCIAVITAE

PYLORIBINDERS - Helicobacter pylori specific biomaterials for antibiotic-free treatment/diagnostic of gastric infection <br>

2016-06-01 to 2019-12-31 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/CTM-BIO/4043/2014

Source: check_circle
CIÊNCIAVITAE

Navigating through marine-derived fungi: bioprospection and synthesis of bioactive secondary metabolites and analogues as chemotherapic agents

2016-06-01 to 2019-06-01 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/MAR-BIO/4694/2014

Source: check_circle
CIÊNCIAVITAE

Targeting p53 family proteins: on the route to new anticancer agents

2016-04-01 to 2019-04-01 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/DTP-FTO/1981/2014

Source: check_circle
CIÊNCIAVITAE

Lipossomas funcionalizados com anticorpos para a doença de Alzheimer

2012-03-01 to 2015-06-30 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/QUI-BIQ/118076/2010

Source: check_circle
CIÊNCIAVITAE

DECIPHERING THE THERAPEUTIC AND TOXIC EFFECTS OF CATIONIC AMPHIPHILIC DRUGS: A COMBINED CHEMICAL AND BIOPHYSICAL APPROACH TO THE INTERACTION OF DRUGS WITH LIPID MODEL SYSTEMS

2012-01-01 to 2016-12-31 | Grant
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

SFRH/BPD/81963/2011

Source: check_circle
CIÊNCIAVITAE

Strategic Project - LA 6 - 2011-2012

2011-01-01 to 2012-12-31 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PEst-C/EQB/LA0006/2011

Source: check_circle
CIÊNCIAVITAE

Development of azacalix(hetero)arene transporters for mediated anionic flux across membranes: a novel approach for studying ionic passive diffusion

2010-06-01 to 2013-12-31 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/QUI-QUI/101022/2008

Source: check_circle
CIÊNCIAVITAE

NOVAS ABORDAGENS PARA O ESTUDO DA ACÇÃO TERAPÊUTICA E DOS EFEITOS SECUNDÁRIOS DOS ANTI-INFLAMATÓRIOS NÃO ESTERÓIDES CONTEMPLANDO ASPECTOS BIOFÍSICOS DA INTERACÇÃO FÁRMACO-MEMBRANA

2008-01-01 to 2011-12-31 | Grant
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

SFRH/BD/38445/2007

Source: check_circle
CIÊNCIAVITAE

Peer review (3 reviews for 3 publications/grants)

Review activity for ACS applied materials & interfaces. (1)
Review activity for Nano letters. (1)
Review activity for The journal of physical chemistry. (1)