Personal information

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Janscak lab

Other IDs

ResearcherID: Q-3795-2018
Scopus Author ID: 6701390459

Keywords

DNA damage, DNA repair, DNA replication stress, R-loops, Genomic instability, Cancer

Countries

Switzerland, Czech Republic

Activities

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Employment (3)

University of Zurich: Zurich, Zurich, CH

2001-09-01 to present | Group Leader/Prof. Dr. (Institute of Molecular Cancer Research)
Employment
Source: Self-asserted source
Pavel Janscak

University of Basel: Basel, Basel-Stadt, CH

1996-08-01 to 2001-07-31 | Postdoc (Department of Microbiology)
Employment
Source: Self-asserted source
Pavel Janscak

University of Portsmouth: Portsmouth, GB

1994-02-01 to 1996-06-30 | Postdoc (School of Biological Sciences)
Employment
Source: Self-asserted source
Pavel Janscak

Education and qualifications (4)

University of Zurich: Zurich, Zurich, CH

2022-07-15 to present | Adjunct Professor (Faculty of Science)
Qualification
Source: Self-asserted source
Pavel Janscak

University of Zurich: Zurich, Zurich, CH

2014-04-14 | Habilitation/PD (Privat Dozent) (Faculty of Science)
Qualification
Source: Self-asserted source
Pavel Janscak

Czech Academy of Sciences: Prague, Prague, CZ

1991-01-01 to 1993-07-01 | PhD (Institute of Microbiology)
Education
Source: Self-asserted source
Pavel Janscak

Charles University: Prague, Prague, CZ

1982-10-01 to 1987-09-22 | MSc. (Department of Biochemistry)
Education
Source: Self-asserted source
Pavel Janscak

Professional activities (2)

University of Zurich: Zurich, Zurich, CH

Cancer Research Center Zurich
Membership
Source: Self-asserted source
Pavel Janscak

University of Zurich: Zurich, Zurich, CH

Cancer Biology Program of the University of Zurich
Membership
Source: Self-asserted source
Pavel Janscak

Funding (6)

Molecular mechanisms underlying transcriptiondependent replication stress induced by RAS oncogenes

2022-08 to 2024-07 | Grant
Swiss Cancer Research Foundation (Bern, CH)
GRANT_NUMBER:

KFS-5484-02-2022
Source: Self-asserted source
Pavel Janscak

Mechanistic insights into the DNA replication restart process at sites of transcription-replication interference

2019-04 to 2023-03 | Grant
Swiss National Science Foundation (Bern, CH)
GRANT_NUMBER:

310030_184716
Source: Self-asserted source
Pavel Janscak

A novel pathway for resolution of collisions between transcription and replication machineries: a potential therapeutic target in cancer

2018-01 to 2019-01 | Grant
Novartis Foundation for medical-biological Research (Basel, CH)
GRANT_NUMBER:

17C188
Source: Self-asserted source
Pavel Janscak

Molecular basis of oncogene-induced DNA damage

2016-09 to 2020-03 | Grant
Swiss Cancer Research Foundation (Bern, CH)
GRANT_NUMBER:

KFS-3802-02-2016
Source: Self-asserted source
Pavel Janscak

Exploring the molecular mechanisms of genome stability maintenance during DNA replication stress

2016-04 to 2019-03 | Grant
Swiss National Science Foundation (Bern, CH)
GRANT_NUMBER:

31003A_166451
Source: Self-asserted source
Pavel Janscak

Role of RECQ5 DNA Helicase in Maintenence of Genomic Stability

2013-04 to 2016-03 | Grant
Swiss National Science Foundation (Bern, CH)
GRANT_NUMBER:

31003A_146206
Source: Self-asserted source
Pavel Janscak

Works (50 of 70)

Items per page:
Page 1 of 2

MutSβ-MutLβ-FANCJ axis mediates the restart of DNA replication after fork stalling at cotranscriptional G4/R-loops

Science Advances
2024 | Journal article
DOI: 10.1126/sciadv.adk2685
EID:

2-s2.0-85184737786

Part of ISSN: 23752548
Contributors: Isik, E.; Shukla, K.; Pospisilova, M.; König, C.; Andrs, M.; Rao, S.; Rosano, V.; Dobrovolna, J.; Krejci, L.; Janscak, P.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

PPM1D activity promotes the replication stress caused by cyclin E1 overexpression

Molecular Oncology
2024 | Journal article
DOI: 10.1002/1878-0261.13433
EID:

2-s2.0-85174264261

Part of ISSN: 18780261 15747891
Contributors: Martinikova, A.S.; Stoyanov, M.; Oravetzova, A.; Kok, Y.P.; Yu, S.; Dobrovolna, J.; Janscak, P.; van Vugt, M.; Macurek, L.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

Excessive reactive oxygen species induce transcription-dependent replication stress

Nature Communications
2023 | Journal article
DOI: 10.1038/s41467-023-37341-y
EID:

2-s2.0-85151316420

Part of ISSN: 20411723
Contributors: Andrs, M.; Stoy, H.; Boleslavska, B.; Chappidi, N.; Kanagaraj, R.; Nascakova, Z.; Menon, S.; Rao, S.; Oravetzova, A.; Dobrovolna, J. et al.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

The importance of nuclear RAGE–Mcm2 axis in diabetes or cancer-associated replication stress

Nucleic Acids Research
2023-03-21 | Journal article | Author
DOI: 10.1093/nar/gkad085
Part of ISSN: 0305-1048
Part of ISSN: 1362-4962
Contributors: Zhe Han; Martin Andrš; Bindhu K Madhavan; Serap Kaymak; Alba Sulaj; Zoltan Kender; Stefan Kopf; Lars Kihm; Rainer Pepperkok; Pavel Janscak et al.
Source: Self-asserted source
Pavel Janscak
grade
Preferred source (of 2)‎

DDX17 helicase promotes resolution of R-loop-mediated transcription–replication conflicts in human cells

Nucleic Acids Research
2022-11-28 | Journal article | Author
DOI: 10.1093/nar/gkac1116
Part of ISSN: 0305-1048
Part of ISSN: 1362-4962
Contributors: Barbora Boleslavská; Anna Oravetzová; 0000-0001-7921-4519; Nascakova; Oluwakemi Ngozi Ibini; Zdenka Hasanova; Martin Andrs; Radhakrishnan Kanagaraj; Jana Dobrovolna; Pavel Janscak
Source: Self-asserted source
Pavel Janscak
grade
Preferred source (of 2)‎

Cancer cells use self-inflicted DNA breaks to evade growth limits imposed by genotoxic stress.

Science (New York, N.Y.)
2022-04-28 | Journal article
DOI: 10.1126/science.abi6378
PMID: 35482866
Contributors: Pavel Janscak
Source: Self-asserted source
Pavel Janscak
grade
Preferred source (of 2)‎

MutSβ regulates G4-associated telomeric R-loops to maintain telomere integrity in ALT cancer cells.

Cell reports
2022-04-01 | Journal article
DOI: 10.1016/j.celrep.2022.110602
PMID: 35385755
Contributors: Pavel Janscak
Source: Self-asserted source
Pavel Janscak
grade
Preferred source (of 2)‎

RAD51 Inhibition Induces R-Loop Formation in Early G1 Phase of the Cell Cycle.

International journal of molecular sciences
2021-04-03 | Journal article
DOI: 10.3390/ijms22073740
PMID: 33916766
PMC: PMC8038378
Contributors: Pavel Janscak
Source: Self-asserted source
Pavel Janscak
grade
Preferred source (of 2)‎

The ALPK1/TIFA/NF-κB axis links a bacterial carcinogen to R-loop-induced replication stress.

Nature communications
2020-10-09 | Journal article
DOI: 10.1038/s41467-020-18857-z
PMID: 33037203
PMC: PMC7547021
Contributors: Pavel Janscak
Source: Self-asserted source
Pavel Janscak
grade
Preferred source (of 2)‎

RECQ5: A Mysterious Helicase at the Interface of DNA Replication and Transcription.

Genes
2020-02-21 | Journal article
DOI: 10.3390/genes11020232
PMID: 32098287
PMC: PMC7073763
Contributors: Pavel Janscak
Source: Self-asserted source
Pavel Janscak
grade
Preferred source (of 2)‎

Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops.

Molecular cell
2019-11-20 | Journal article
DOI: 10.1016/j.molcel.2019.10.026
PMID: 31759821
Contributors: Pavel Janscak
Source: Self-asserted source
Pavel Janscak
grade
Preferred source (of 2)‎

Efficient Pre-mRNA Cleavage Prevents Replication-Stress-Associated Genome Instability.

Molecular cell
2019-01-10 | Journal article
DOI: 10.1016/j.molcel.2018.11.036
PMID: 30639241
PMC: PMC6395949
Contributors: Pavel Janscak
Source: Self-asserted source
Pavel Janscak
grade
Preferred source (of 2)‎

Replication fork reversal triggers fork degradation in BRCA2-defective cells.

Nature communications
2017-10-16 | Journal article
DOI: 10.1038/s41467-017-01164-5
PMID: 29038466
PMC: PMC5643541
Contributors: Pavel Janscak
Source: Self-asserted source
Pavel Janscak
grade
Preferred source (of 2)‎

RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis.

Molecular cell
2017-06-01 | Journal article
DOI: 10.1016/j.molcel.2017.05.006
PMID: 28575661
Contributors: Pavel Janscak
Source: Self-asserted source
Pavel Janscak
grade
Preferred source (of 2)‎

Interplay with the Mre11-Rad50-Nbs1 complex and phosphorylation by GSK3β implicate human B-Myb in DNA-damage signaling.

Scientific reports
2017-01-27 | Journal article
DOI: 10.1038/srep41663
PMID: 28128338
PMC: PMC5269693
Contributors: Pavel Janscak
Source: Self-asserted source
Pavel Janscak
grade
Preferred source (of 2)‎

The MMS22L–TONSL heterodimer directly promotes RAD51‐dependent recombination upon replication stress

The EMBO Journal
2016-12 | Journal article
DOI: 10.15252/embj.201593132
Part of ISSN: 0261-4189
Part of ISSN: 1460-2075
Contributors: Pavel Janscak
Source: Self-asserted source
Pavel Janscak
grade
Preferred source (of 2)‎

Distinct functions of human RecQ helicases during DNA replication.

Biophysical chemistry
2016-11-15 | Journal article
DOI: 10.1016/j.bpc.2016.11.005
PMID: 27876204
Contributors: Pavel Janscak
Source: Self-asserted source
Pavel Janscak
grade
Preferred source (of 2)‎

RECQ5 helicase promotes resolution of conflicts between replication and transcription in human cells

Journal of Cell Biology
2016-08-15 | Journal article
DOI: 10.1083/jcb.201507099
Part of ISSN: 0021-9525
Part of ISSN: 1540-8140
Contributors: Pavel Janscak
Source: Self-asserted source
Pavel Janscak
grade
Preferred source (of 2)‎

A Comparative Study of G-Quadruplex Unfolding and DNA Reeling Activities of Human RECQ5 Helicase

Biophysical Journal
2016-06 | Journal article
DOI: 10.1016/j.bpj.2016.05.016
Part of ISSN: 0006-3495
Contributors: Pavel Janscak
Source: Self-asserted source
Pavel Janscak
grade
Preferred source (of 2)‎

The Mismatch-Binding Factor MutSβ Can Mediate ATR Activation in Response to DNA Double-Strand Breaks

Molecular Cell
2015-08 | Journal article
DOI: 10.1016/j.molcel.2015.06.026
Part of ISSN: 1097-2765
Contributors: Pavel Janscak
Source: Self-asserted source
Pavel Janscak
grade
Preferred source (of 2)‎

Functional Coupling of Duplex Translocation to DNA Cleavage in a Type I Restriction Enzyme

PLOS ONE
2015-06-03 | Journal article
DOI: 10.1371/journal.pone.0128700
Part of ISSN: 1932-6203
Contributors: Pavel Janscak
Source: Self-asserted source
Pavel Janscak
grade
Preferred source (of 2)‎

Mechanistic insight into the interaction of BLM helicase with intra-strand G-quadruplex structures

Nature Communications
2014-12 | Journal article
DOI: 10.1038/ncomms6556
Part of ISSN: 2041-1723
Contributors: Pavel Janscak
Source: Self-asserted source
Pavel Janscak
grade
Preferred source (of 2)‎

RecQ-core of BLM unfolds telomeric G-quadruplex in the absence of ATP

Nucleic Acids Research
2014-10-13 | Journal article
DOI: 10.1093/nar/gku856
Part of ISSN: 1362-4962
Part of ISSN: 0305-1048
Contributors: Pavel Janscak
Source: Self-asserted source
Pavel Janscak
grade
Preferred source (of 2)‎

DNA2 Cooperates with the WRN and BLM RecQ Helicases to Mediate Long-range DNA End Resection in Human Cells

Journal of Biological Chemistry
2014-09 | Journal article
DOI: 10.1074/jbc.m114.578823
Part of ISSN: 0021-9258
Contributors: Pavel Janscak
Source: Self-asserted source
Pavel Janscak
grade
Preferred source (of 2)‎

Human RECQ5 helicase promotes repair of DNA double-strand breaks by synthesis-dependent strand annealing

Nucleic Acids Research
2014-02-01 | Journal article
DOI: 10.1093/nar/gkt1263
Part of ISSN: 1362-4962
Part of ISSN: 0305-1048
Contributors: Pavel Janscak
Source: Self-asserted source
Pavel Janscak
grade
Preferred source (of 2)‎

FBH1 helicase disrupts RAD51 filaments in vitro and modulates homologous recombination in mammalian cells

Journal of Biological Chemistry
2013 | Journal article
DOI: 10.1074/jbc.M113.484493
EID:

2-s2.0-84888362110

Part of ISSN: 1083351X 00219258
Contributors: Simandlova, J.; Zagelbaum, J.; Payne, M.J.; Chu, W.K.; Shevelev, I.; Hanada, K.; Chatterjee, S.; Reid, D.A.; Liu, Y.; Janscak, P. et al.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

Prolyl isomerase PIN1 regulates DNA double-strand break repair by counteracting DNA end resection

Molecular Cell
2013 | Journal article
DOI: 10.1016/j.molcel.2013.03.023
EID:

2-s2.0-84883599853

Part of ISSN: 10972765 10974164
Contributors: Steger, M.; Murina, O.; Hühn, D.; Ferretti, L.P.; Walser, R.; Hänggi, K.; Lafranchi, L.; Neugebauer, C.; Paliwal, S.; Janscak, P. et al.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

Involvement of Werner syndrome protein in MUTYH-mediated repair of oxidative DNA damage

Nucleic Acids Research
2012 | Journal article
DOI: 10.1093/nar/gks648
EID:

2-s2.0-84866893075

Part of ISSN: 03051048 13624962
Contributors: Kanagaraj, R.; Parasuraman, P.; Mihaljevic, B.; Van Loon, B.; Burdova, K.; König, C.; Furrer, A.; Bohr, V.A.; Hübscher, U.; Janscak, P.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

The human RecQ helicases BLM and RECQL4 cooperate to preserve genome stability

Nucleic Acids Research
2012 | Journal article
DOI: 10.1093/nar/gks349
EID:

2-s2.0-84864951093

Part of ISSN: 03051048 13624962
Contributors: Singh, D.K.; Popuri, V.; Kulikowicz, T.; Shevelev, I.; Ghosh, A.K.; Ramamoorthy, M.; Rossi, M.L.; Janscak, P.; Croteau, D.L.; Bohr, V.A.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks

Nature Cell Biology
2011 | Journal article
DOI: 10.1038/ncb2367
EID:

2-s2.0-80455145246

Part of ISSN: 14657392 14764679
Contributors: Meerang, M.; Ritz, D.; Paliwal, S.; Garajova, Z.; Bosshard, M.; Mailand, N.; Janscak, P.; Hübscher, U.; Meyer, H.; Ramadan, K.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

Human RECQL5β stimulates flap endonuclease 1

Nucleic Acids Research
2010 | Journal article
DOI: 10.1093/nar/gkp1217
EID:

2-s2.0-77953250133

Part of ISSN: 03051048 13624962
Contributors: Speina, E.; Dawut, L.; Hedayati, M.; Wang, Z.; May, A.; Schwendener, S.; Janscak, P.; Croteau, D.L.; Bohr, V.A.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

Physical interaction of RECQ5 helicase with RAD51 facilitates its anti-recombinase activity

Journal of Biological Chemistry
2010 | Journal article
DOI: 10.1074/jbc.M110.110478
EID:

2-s2.0-77952372219

Part of ISSN: 00219258 1083351X
Contributors: Schwendener, S.; Raynard, S.; Paliwal, S.; Cheng, A.; Kanagaraj, R.; Shevelev, I.; Stark, J.M.; Sung, P.; Janscak, P.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

RECQ5 helicase associates with the C-terminal repeat domain of RNA polymerase II during productive elongation phase of transcription

Nucleic Acids Research
2010 | Journal article
DOI: 10.1093/nar/gkq697
EID:

2-s2.0-77958595004

Part of ISSN: 03051048 13624962
Contributors: Kanagaraj, R.; Huehn, D.; MacKellar, A.; Menigatti, M.; Zheng, L.; Urban, V.; Shevelev, I.; Greenleaf, A.L.; Janscak, P.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

BLM helicase measures DNA unwound before switching strands and hRPA promotes unwinding reinitiation

EMBO Journal
2009 | Journal article
DOI: 10.1038/emboj.2008.298
EID:

2-s2.0-60549117657

Part of ISSN: 02614189 14602075
Contributors: Yodh, J.G.; Stevens, B.C.; Kanagaraj, R.; Janscak, P.; Ha, T.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

Erratum: p300-mediated acetylation of the Rothmund-Thomson-syndrome gene product RECQL4 regulates its subcellular localization (Journal of Cell Science vol. 122 (1258-1267))

Journal of Cell Science
2009 | Journal article
DOI: 10.1242/jcs.052944
EID:

2-s2.0-67650513829

Part of ISSN: 00219533
Contributors: Dietschy, T.; Shevelev, I.; Pena-Diaz, J.; Hühn, D.; Kuenzle, S.; Mak, R.; Miah, M.F.; Hess, D.; Fey, M.; Hottiger, M.O. et al.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

MRE11 complex links RECQ5 helicase to sites of DNA damage

Nucleic Acids Research
2009 | Journal article
DOI: 10.1093/nar/gkp147
EID:

2-s2.0-65849390687

Part of ISSN: 03051048 13624962
Contributors: Zheng, L.; Kanagaraj, R.; Mihaljevic, B.; Schwendener, S.; Sartori, A.A.; Gerrits, B.; Shevelev, I.; Janscak, P.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

P300-mediated acetylation of the Rothmund-Thomson-syndrome gene product RECQL4 regulates its subcellular localization

Journal of Cell Science
2009 | Journal article
DOI: 10.1242/jcs.037747
EID:

2-s2.0-66849089384

Part of ISSN: 00219533
Contributors: Dietschy, T.; Shevelev, I.; Pena-Diaz, J.; Hühn, D.; Kuenzle, S.; Mak, R.; Miah, M.F.; Hess, D.; Fey, M.; Hottiger, M.O. et al.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

Structure of the motor subunit of type I restriction-modification complex EcoR124I

Nature Structural and Molecular Biology
2009 | Journal article
DOI: 10.1038/nsmb.1523
EID:

2-s2.0-58149269108

Part of ISSN: 15459993 15459985
Contributors: Lapkouski, M.; Panjikar, S.; Janscak, P.; Smatanova, I.K.; Carey, J.; Ettrich, R.; Csefalvay, E.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

Constitutive phosphorylation of MDC1 physically links the MRE11-RAD50-NBS1 complex to damaged chromatin

Journal of Cell Biology
2008 | Journal article
DOI: 10.1083/jcb.200709008
EID:

2-s2.0-42449115711

Part of ISSN: 00219525 00219525
Contributors: Spycher, C.; Miller, E.S.; Townsend, K.; Pavic, L.; Morrice, N.A.; Janscak, P.; Stewart, G.S.; Stucki, M.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

The zinc-binding motif of human RECQ5β suppresses the intrinsic strand-annealing activity of its DExH helicase domain and is essential for the helicase activity of the enzyme

Biochemical Journal
2008 | Journal article
DOI: 10.1042/BJ20071150
EID:

2-s2.0-45349089153

Part of ISSN: 02646021
Contributors: Ren, H.; Dou, S.-X.; Zhang, X.-D.; Wang, P.-Y.; Kanagaraj, R.; Liu, J.-L.; Janscak, P.; Hu, J.-S.; Xi, X.G.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

Physical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factors

Nucleic Acids Research
2007 | Journal article
DOI: 10.1093/nar/gkm500
EID:

2-s2.0-34848881418

Part of ISSN: 03051048 13624962
Contributors: Saydam, N.; Kanagaraj, R.; Dietschy, T.; Garcia, P.I.; Peña-Diaz, J.; Shevelev, I.; Stagljar, I.; Janscak, P.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments

Genes and Development
2007 | Journal article
DOI: 10.1101/gad.1609107
EID:

2-s2.0-36849013079

Part of ISSN: 08909369 15495477
Contributors: Hu, Y.; Raynard, S.; Sehorn, M.G.; Lu, X.; Bussen, W.; Zheng, L.; Stark, J.M.; Barnes, E.L.; Chi, P.; Janscak, P. et al.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

The Werner syndrome protein is required for recruitment of chromatin assembly factor 1 following DNA damage

Oncogene
2007 | Journal article
DOI: 10.1038/sj.onc.1210150
EID:

2-s2.0-34249948113

Part of ISSN: 09509232 14765594
Contributors: Jiao, R.; Harrigan, J.A.; Shevelev, I.; Dietschy, T.; Selak, N.; Indig, F.E.; Piotrowski, J.; Janscak, P.; Bohr, V.A.; Stagljar, I.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

Human RECQ5β helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication fork

Nucleic Acids Research
2006 | Journal article
DOI: 10.1093/nar/gkl677
EID:

2-s2.0-33750980979

Part of ISSN: 03051048 13624962
Contributors: Kanagaraj, R.; Saydam, N.; Garcia, P.L.; Zheng, L.; Janscak, P.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

Degradation of human exonuclease 1b upon DNA synthesis inhibition

Cancer Research
2005 | Journal article
DOI: 10.1158/0008-5472.CAN-04-4069
EID:

2-s2.0-18144381942

Part of ISSN: 00085472
Contributors: El-Shemerly, M.; Janscak, P.; Hess, D.; Jiricny, J.; Ferrari, S.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

On the DNA cleavage mechanism of Type I restriction enzymes

Nucleic Acids Research
2005 | Journal article
DOI: 10.1093/nar/gki322
EID:

2-s2.0-15944421803

Part of ISSN: 03051048 13624962
Contributors: Jindrova, E.; Schmid-Nuoffer, S.; Hamburger, F.; Janscak, P.; Bickle, T.A.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

The Bloom's syndrome helicase promotes the annealing of complementary single-stranded DNA

Nucleic Acids Research
2005 | Journal article
DOI: 10.1093/nar/gki712
EID:

2-s2.0-22444447945

Part of ISSN: 03051048 13624962
Contributors: Cheok, C.F.; Wu, L.; Garcia, P.L.; Janscak, P.; Hickson, I.D.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

The HRDC domain of BLM is required for the dissolution of double Holliday junctions

EMBO Journal
2005 | Journal article
DOI: 10.1038/sj.emboj.7600740
EID:

2-s2.0-23044449199

Part of ISSN: 02614189
Contributors: Wu, L.; Chan, K.L.; Ralf, C.; Bernstein, D.A.; Garcia, P.L.; Bohr, V.A.; Vindigni, A.; Janscak, P.; Keck, J.L.; Hickson, I.D.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

Human RECQ51β, a protein with DNA helicase and strand-annealing activities in a single polypeptide

EMBO Journal
2004 | Journal article
DOI: 10.1038/sj.emboj.7600301
EID:

2-s2.0-3543007196

Part of ISSN: 02614189
Contributors: Garcia, P.L.; Liu, Y.; Jiricny, J.; West, S.C.; Janscak, P.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier

RPA alleviates the inhibitory effect of vinylphosphonate internucleotide linkages on DNA unwinding by BLM and WRN helicases

Nucleic Acids Research
2004 | Journal article
DOI: 10.1093/nar/gkh709
EID:

2-s2.0-3142708510

Part of ISSN: 03051048
Contributors: Garcia, P.L.; Bradley, G.; Hayes, C.J.; Krintel, S.; Soultanas, P.; Janscak, P.
Source: Self-asserted source
Pavel Janscak via Scopus - Elsevier
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