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Harvard T.H. Chan School of Public Health: Boston, MA, US

2023-01-13 to present | Chair (Environmental Health)
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kari nadeau

Works (50 of 57)

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Effect of altered human exposome on the skin and mucosal epithelial barrier integrity

Tissue Barriers
2023-10-02 | Journal article
DOI: 10.1080/21688370.2022.2133877
Contributors: Yagiz Pat; Ismail Ogulur; Duygu Yazici; Yasutaka Mitamura; Lacin Cevhertas; Ozan C. Küçükkase; Sanne S. Mesisser; Mübeccel Akdis; Kari Nadeau; Cezmi A. Akdis
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Crossref

Editorial comments on “Early initiation of short‐term emollient use for the prevention of atopic dermatitis in high‐risk infants—The STOP‐AD randomized controlled trial”—Is emollient therapy enough?

Allergy
2023-04 | Journal article
DOI: 10.1111/all.15626
Contributors: Helen A. Brough; Sayantani Sindher; Kari C. Nadeau
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Exponential magnetophoretic gradient for the direct isolation of basophils from whole blood in a microfluidic system

Lab on a Chip
2022 | Journal article
DOI: 10.1039/D2LC00154C
Contributors: Nicolas Castaño; Sungu Kim; Adrian M. Martin; Stephen J. Galli; Kari C. Nadeau; Sindy K. Y. Tang
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Crossref

Human and planetary health on fire

Nature Reviews Immunology
2022-11 | Journal article
DOI: 10.1038/s41577-022-00776-3
Contributors: Cezmi A. Akdis; Kari C. Nadeau
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Crossref

Proinflammatory polarization of monocytes by particulate air pollutants is mediated by induction of trained immunity in pediatric asthma

2022-11-10 | Preprint
DOI: 10.22541/au.166806366.68188863/v1
Contributors: Kari Nadeau; Hesam Movassagh; Mary Prunicki; Abhinav Kaushik; Xiaoying Zhou; Diane Dunham; Eric Smith; Ziyuan He; German R. Aleman Muench; Minyi Shi et al.
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Crossref

Selenomethionine attenuates allergic effector responses in human primary mast cells

Allergy
2022-08 | Journal article
DOI: 10.1111/all.15320
Contributors: Xiaoli Zhao; Bart. R. J. Blokhuis; Frank. A. Redegeld; Iris Chang; Diane Dunham; Hongbing Chen; Kari Nadeau; Johan Garssen; Leon M. J. Knippels; Astrid Hogenkamp
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Crossref

World Health Organization global air quality guideline recommendations: Executive summary

Allergy
2022-07 | Journal article
DOI: 10.1111/all.15224
Contributors: Anna Goshua; Cezmi A. Akdis; Kari C. Nadeau
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Crossref

The relationship between the gut microbiome and the risk of respiratory infections among newborns

Communications Medicine
2022-07-14 | Journal article
DOI: 10.1038/s43856-022-00152-1
Contributors: Yuka Moroishi; Jiang Gui; Anne G. Hoen; Hilary G. Morrison; Emily R. Baker; Kari C. Nadeau; Hongzhe Li; Zhigang Li; Juliette C. Madan; Margaret R. Karagas
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Crossref

Food allergy, mechanisms, diagnosis and treatment: Innovation through a multi‐targeted approach

Allergy
2022-06-22 | Journal article
DOI: 10.1111/all.15418
Contributors: Sayantani B. Sindher; Andrew Long; Andrew R. Chin; Angela Hy; Vanitha Sampath; Kari C. Nadeau; R. Sharon Chinthrajah
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Crossref

Climate change: A call to action for the United Nations

Allergy
2022-04 | Journal article
DOI: 10.1111/all.15079
Contributors: Kari C. Nadeau; Ioana Agache; Marek Jutel; Isabella Annesi Maesano; Mübeccel Akdis; Vanitha Sampath; Gennaro D'Amato; Lorenzo Cecchi; Claudia Traidl‐Hoffmann; Cezmi A. Akdis
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Exponential magnetophoretic gradient for the direct isolation of basophils from whole blood in a microfluidic system

2022-02-11 | Preprint
DOI: 10.1101/2022.02.11.480005
Contributors: Nicolas Castaño; Sungu Kim; Adrian M. Martin; Stephen J. Galli; Kari C. Nadeau; Sindy K.Y. Tang
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Crossref

Shrimp‐allergic patients in a multi‐food oral immunotherapy trial

Pediatric Allergy and Immunology
2022-01 | Journal article
DOI: 10.1111/pai.13679
Contributors: Diem‐Tran I. Nguyen; Sayantani B. Sindher; R. Sharon Chinthrajah; Kari Nadeau; Carla M. Davis; Motohiro Ebisawa
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Early peanut introduction wins over the HLA-DQA1*01:02 allele in the interplay between environment and genetics

Journal of Clinical Investigation
2022-01-04 | Journal article
DOI: 10.1172/JCI155609
Contributors: Monali Manohar; Kari Christine Nadeau; Maya Kasowski
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Crossref

Women in science and medicine

Allergy
2021-12 | Journal article
DOI: 10.1111/all.14967
Contributors: Ruby Pawankar; Mariana Castells; Mübeccel Akdis; Kari Nadeau; Agnes Sze Yin Leung
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Temporal changes in soluble angiotensin-converting enzyme 2 associated with metabolic health, body composition, and proteome dynamics during a weight loss diet intervention: a randomized trial with implications for the COVID-19 pandemic

The American Journal of Clinical Nutrition
2021-11 | Journal article
DOI: 10.1093/ajcn/nqab243
Contributors: Nicholas Cauwenberghs; Mary Prunicki; František Sabovčik; Dalia Perelman; Kévin Contrepois; Xiao Li; Michael P Snyder; Kari C Nadeau; Tatiana Kuznetsova; Francois Haddad et al.
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Maternal gestational mercury exposure in relation to cord blood T cell alterations and placental gene expression signatures

Environmental Research
2021-10 | Journal article
DOI: 10.1016/j.envres.2021.111385
Contributors: Hesam Movassagh; Yuliya Halchenko; Vanitha Sampath; Unni C. Nygaard; Brian Jackson; David Robbins; Zhigang Li; Kari C. Nadeau; Margaret R. Karagas
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CD8 + T cells specific for conserved coronavirus epitopes correlate with milder disease in patients with COVID-19

Science Immunology
2021-07-29 | Journal article
DOI: 10.1126/sciimmunol.abg5669
Contributors: Vamsee Mallajosyula; Conner Ganjavi; Saborni Chakraborty; Alana M. McSween; Ana Jimena Pavlovitch-Bedzyk; Julie Wilhelmy; Allison Nau; Monali Manohar; Kari C. Nadeau; Mark M. Davis
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A positive feedback loop reinforces the allergic immune response in human peanut allergy

Journal of Experimental Medicine
2021-07-05 | Journal article
DOI: 10.1084/jem.20201793
Contributors: Xiaoying Zhou; Wong Yu; Shu-Chen Lyu; Claudia Macaubas; Bryan Bunning; Ziyuan He; Elizabeth D. Mellins; Kari C. Nadeau
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Allergen-specific IgG Antibodies for Cat Allergy?

American Journal of Respiratory and Critical Care Medicine
2021-07-01 | Journal article
DOI: 10.1164/rccm.202103-0662ED
Contributors: Kari C. Nadeau
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EAACI statement on the diagnosis, management and prevention of severe allergic reactions to COVID‐19 vaccines

Allergy
2021-06 | Journal article
DOI: 10.1111/all.14739
Contributors: Milena Sokolowska; Thomas Eiwegger; Markus Ollert; Maria J. Torres; Domingo Barber; Stefano Del Giacco; Marek Jutel; Kari C. Nadeau; Oscar Palomares; Ronald L. Rabin et al.
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Bayesian hierarchical evaluation of dose-response for peanut allergy in clinical trial screening

Food and Chemical Toxicology
2021-05 | Journal article
DOI: 10.1016/j.fct.2021.112125
Contributors: Lynne T. Haber; John F. Reichard; Alice K. Henning; Peter Dawson; R. Sharon Chinthrajah; Sayantani B. Sindher; Andrew Long; Melissa J. Vincent; Kari C. Nadeau; Bruce C. Allen
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Identification of Pru du 6 as a potential marker allergen for almond allergy

Allergy
2021-05 | Journal article
DOI: 10.1111/all.14613
Contributors: Stefan Kabasser; Christine Hafner; Sharon Chinthrajah; Sayantani B. Sindher; Divya Kumar; Laurie E. Kost; Andrew J. Long; Kari C. Nadeau; Heimo Breiteneder; Merima Bublin
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Vitamin D insufficiency is associated with reduced regulatory T cell frequency in food‐allergic infants

Pediatric Allergy and Immunology
2021-05 | Journal article
DOI: 10.1111/pai.13439
Contributors: Melanie R. Neeland; Amanda R. Tursi; Kirsten P. Perrett; Richard Saffery; Jennifer J. Koplin; Kari C. Nadeau; Sandra Andorf
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SARS-CoV-2 infection and COVID-19 in asthmatics: a complex relationship

Nature Reviews Immunology
2021-04-23 | Journal article
DOI: 10.1038/s41577-021-00516-z
Contributors: Chrysanthi Skevaki; Antonina Karsonova; Alexander Karaulov; Daria Fomina; Min Xie; Sharon Chinthrajah; Kari C. Nadeau; Harald Renz
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Crossref

ARIA‐EAACI statement on asthma and COVID‐19 (June 2, 2020)

Allergy
2021-03 | Journal article
DOI: 10.1111/all.14471
Contributors: Jean Bousquet; Marek Jutel; Cezmi A. Akdis; Ludger Klimek; Oliver Pfaar; Kari C. Nadeau; Thomas Eiwegger; Anna Bedbrook; Ignacio J. Ansotegui; Josep M. Anto et al.
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Crossref

Modeling Predictive Age-Dependent and Age-Independent Symptoms and Comorbidities of Patients Seeking Treatment for COVID-19: Model Development and Validation Study

Journal of Medical Internet Research
2021-03-25 | Journal article
DOI: 10.2196/25696
Contributors: Yingxiang Huang; Dina Radenkovic; Kevin Perez; Kari Nadeau; Eric Verdin; David Furman
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Crossref

Targeted DNA methylation profiling reveals epigenetic signatures in peanut allergy

JCI Insight
2021-03-22 | Journal article
DOI: 10.1172/jci.insight.143058
Contributors: Xiaoying Zhou; Xiaorui Han; Shu-Chen Lyu; Bryan Bunning; Laurie Kost; Iris Chang; Shu Cao; Vanitha Sampath; Kari C. Nadeau
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Crossref

Early intervention of atopic dermatitis as a preventive strategy for progression of food allergy

Allergy, Asthma & Clinical Immunology
2021-03-16 | Journal article
DOI: 10.1186/s13223-021-00531-8
Contributors: Alyssa Sweeney; Vanitha Sampath; Kari C. Nadeau
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Crossref

Advances and novel developments in mechanisms of allergic inflammation

Allergy
2020-12 | Journal article
DOI: 10.1111/all.14632
Contributors: Xiaorui Han; James W. Krempski; Kari Nadeau
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Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma

Allergy
2020-12 | Journal article
DOI: 10.1111/all.14582
Contributors: Heimo Breiteneder; Ya‐Qi Peng; Ioana Agache; Zuzana Diamant; Thomas Eiwegger; Wytske J. Fokkens; Claudia Traidl‐Hoffmann; Kari Nadeau; Robyn E. O'Hehir; Liam O'Mahony et al.
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A highly sensitive bioluminescent method for measuring allergen‐specific IgE in microliter samples

Allergy
2020-11 | Journal article
DOI: 10.1111/all.14365
Contributors: Sophie Goyard; Bianca Balbino; Rebecca S. Chinthrajah; Shu‐Chen Lyu; Yves L. Janin; Pierre Bruhns; Pascal Poncet; Stephen J. Galli; Kari C. Nadeau; Laurent L. Reber et al.
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Mass Cytometry Phenotyping of Human Granulocytes Reveals Novel Basophil Functional Heterogeneity

iScience
2020-11 | Journal article
DOI: 10.1016/j.isci.2020.101724
Contributors: Nora Vivanco Gonzalez; John-Paul Oliveria; Dmitry Tebaykin; Geoffrey T. Ivison; Kaori Mukai; Mindy M. Tsai; Luciene Borges; Kari C. Nadeau; Stephen J. Galli; Albert G. Tsai et al.
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Modeling Predictive Age-Dependent and Age-Independent Symptoms and Comorbidities of Patients Seeking Treatment for COVID-19: Model Development and Validation Study (Preprint)

2020-11-14 | Other
DOI: 10.2196/preprints.25696
Contributors: Yingxiang Huang; Dina Radenkovic; Kevin Perez; Kari Nadeau; Eric Verdin; David Furman
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Pilot study measuring transepidermal water loss (TEWL) in children suggests trilipid cream is more effective than a paraffin‐based emollient

Allergy
2020-10 | Journal article
DOI: 10.1111/all.14275
Contributors: Sayantani Sindher; Shifaa S. Alkotob; Melanie N. Shojinaga; Helen A. Brough; Henry T. Bahnson; Susan Chan; Gideon Lack; Donald Y. M. Leung; Kari C. Nadeau
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Immune biomarkers link air pollution exposure to blood pressure in adolescents

Environmental Health
2020-10-16 | Journal article
DOI: 10.1186/s12940-020-00662-2
Contributors: Mary Prunicki; Nicholas Cauwenberghs; Jennifer Arthur Ataam; Hesam Movassagh; Juyong Brian Kim; Tatiana Kuznetsova; Joseph C. Wu; Holden Maecker; Francois Haddad; Kari Nadeau
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Epicutaneous sensitization in the development of food allergy: What is the evidence and how can this be prevented?

Allergy
2020-09 | Journal article
DOI: 10.1111/all.14304
Contributors: Helen A. Brough; Kari C. Nadeau; Sayantani B. Sindher; Shifaa S. Alkotob; Susan Chan; Henry T. Bahnson; Donald Y. M. Leung; Gideon Lack
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Immunologic effects of forest fire exposure show increases in IL‐1β and CRP

Allergy
2020-09 | Journal article
DOI: 10.1111/all.14251
Contributors: Mary M. Prunicki; Christopher C. Dant; Shu Cao; Holden Maecker; Francois Haddad; Juyong B. Kim; Michael Snyder; Joseph Wu; Kari Nadeau
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Phenotype consensus is required to enable large‐scale genetic consortium studies of food allergy

Allergy
2020-09 | Journal article
DOI: 10.1111/all.14333
Contributors: Yuka Asai; David Martino; Thomas Eiwegger; Kari Nadeau; Gerard H. Koppelman; Ann E. Clarke; Young‐Ae Lee; Edmond S. Chan; Elinor Simons; Catherine Laprise et al.
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Identification of cross‐reactive allergens in cashew‐ and pistachio‐allergic children during oral immunotherapy

Pediatric Allergy and Immunology
2020-08 | Journal article
DOI: 10.1111/pai.13258
Contributors: Ziyuan He; Prachi Dongre; Shu‐Chen Lyu; Monali Manohar; R. Sharon Chinthrajah; Stephen J. Galli; Rosemarie H. DeKruyff; Kari C. Nadeau; Sandra Andorf; Hugh Sampson
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Immune response to SARS‐CoV‐2 and mechanisms of immunopathological changes in COVID‐19

Allergy
2020-07 | Journal article
DOI: 10.1111/all.14364
Contributors: Ahmet Kursat Azkur; Mübeccel Akdis; Dilek Azkur; Milena Sokolowska; Willem van de Veen; Marie‐Charlotte Brüggen; Liam O’Mahony; Yadong Gao; Kari Nadeau; Cezmi A. Akdis
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Can food allergy be cured? What are the future prospects?

Allergy
2020-06 | Journal article
DOI: 10.1111/all.14116
Contributors: Vanitha Sampath; Sayantani B. Sindher; Andres M. Alvarez Pinzon; Kari C. Nadeau
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Th2A and Th17 cell frequencies and regulatory markers as follow‐up biomarker candidates for successful multifood oral immunotherapy

Allergy
2020-06 | Journal article
DOI: 10.1111/all.14180
Contributors: Sonia Luce; Sharon Chinthrajah; Shu-Chen Lyu; Kari C. Nadeau; Laurent Mascarell
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Trends in egg specific immunoglobulin levels during natural tolerance and oral immunotherapy

Allergy
2020-06 | Journal article
DOI: 10.1111/all.14107
Contributors: Sandra Andorf; Bryan Bunning; Dana Tupa; Shu Cao; Andrew J. Long; Magnus P. Borres; Stephen J. Galli; Rebecca S. Chinthrajah; Kari C. Nadeau
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Transcriptomic and methylomic features in asthmatic and nonasthmatic twins

Allergy
2020-04 | Journal article
DOI: 10.1111/all.14128
Contributors: Gopal Krishna R. Dhondalay; Bryan Bunning; Rebecca N. Bauer; Elliot S. Barnathan; Christopher Maniscalco; Frédéric Baribaud; Kari C. Nadeau; Sandra Andorf
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Crossref

Microfluidic methods for precision diagnostics in food allergy

Biomicrofluidics
2020-03 | Journal article
DOI: 10.1063/1.5144135
Contributors: Nicolas Castaño; Seth C. Cordts; Kari C. Nadeau; Mindy Tsai; Stephen J. Galli; Sindy K. Y. Tang
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Legends of Allergy: Stephen J. Galli

Allergy
2020-01 | Journal article
DOI: 10.1111/all.13815
Contributors: Mindy Tsai; Sharon Chinthrajah; Kari C. Nadeau
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Future research trends in understanding the mechanisms underlying allergic diseases for improved patient care

Allergy
2019-12 | Journal article
DOI: 10.1111/all.13851
Contributors: Heimo Breiteneder; Zuzana Diamant; Thomas Eiwegger; Wytske J. Fokkens; Claudia Traidl‐Hoffmann; Kari Nadeau; Robyn E. O’Hehir; Liam O’Mahony; Oliver Pfaar; Maria J. Torres et al.
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Phase 2a randomized, placebo-controlled study of anti–IL-33 in peanut allergy

JCI Insight
2019-11-14 | Journal article
DOI: 10.1172/jci.insight.131347
Contributors: Sharon Chinthrajah; Shu Cao; Cherie Liu; Shu-Chen Lyu; Sayantani B. Sindher; Andrew Long; Vanitha Sampath; Daniel Petroni; Marco Londei; Kari C. Nadeau
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The impact of prescribed fire versus wildfire on the immune and cardiovascular systems of children

Allergy
2019-10 | Journal article
DOI: 10.1111/all.13825
Contributors: Mary Prunicki; Rodd Kelsey; Justin Lee; Xiaoying Zhou; Edward Smith; Francois Haddad; Joseph Wu; Kari Nadeau
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Immunoglobulin E blockade during food allergen ingestion enhances the induction of inhibitory immunoglobulin G antibodies

Annals of Allergy, Asthma & Immunology
2019-02 | Journal article
DOI: 10.1016/j.anai.2018.10.024
Contributors: Amanda J. Stranks; Samantha C. Minnicozzi; Samuel J. Miller; Oliver T. Burton; Stephanie L. Logsdon; Jonathan M. Spergel; Kari C. Nadeau; Jacqueline A. Pongracic; Dale T. Umetsu; Rima Rachid et al.
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