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Works (25)

The Role of Genetic Variation in Shaping Phenotypic Responses to Diet in AgingDrosophila melanogaster

2025-01-14 | Preprint
DOI: 10.1101/2025.01.09.632132
Contributors: Nikolaj Klausholt Bak; Trudy F. C. Mackay; Fabio Morgante; Kåre Lehmann Nielsen; Jeppe Lund Nielsen; Torsten Nygaard Kristensen; Palle Duun Rohde
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Pleiotropy, epistasis and the genetic architecture of quantitative traits

Nature Reviews Genetics
2024-09 | Journal article
DOI: 10.1038/s41576-024-00711-3
Contributors: Trudy F. C. Mackay; Robert R. H. Anholt
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The genetic basis of incipient sexual isolation in Drosophila melanogaster

Proceedings of the Royal Society B: Biological Sciences
2024-08 | Journal article
DOI: 10.1098/rspb.2024.0672
Contributors: Akihiko Yamamoto; Wen Huang; Mary Anna Carbone; Robert R. H. Anholt; Trudy F. C. Mackay
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The genetic basis of variation in Drosophila melanogaster mating behavior

iScience
2024-05 | Journal article
DOI: 10.1016/j.isci.2024.109837
Contributors: Akihiko Yamamoto; Wen Huang; Robert R.H. Anholt; Trudy F.C. Mackay
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Early-life nutrition interacts with developmental genes to shape the brain and sleep behavior in Drosophila melanogaster

Sleep
2023-04-12 | Journal article
DOI: 10.1093/sleep/zsad016
Contributors: Gonzalo H Olivares; Franco Núñez-Villegas; Noemi Candia; Karen Oróstica; M Constanza González-Ramírez; Franco Vega-Macaya; Nolberto Zúñiga; Cristian Molina; Carlos Oliva; Trudy F C Mackay et al.
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Natural genetic variation in a dopamine receptor is associated with variation in female fertility in Drosophila melanogaster

Proceedings of the Royal Society B: Biological Sciences
2023-04-12 | Journal article
DOI: 10.1098/rspb.2023.0375
Contributors: Richard F. Lyman; Rachel A. Lyman; Akihiko Yamamoto; Wen Huang; Susan T. Harbison; Shanshan Zhou; Robert R. H. Anholt; Trudy F. C. Mackay
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Pleiotropic fitness effects of a Drosophila odorant-binding protein

G3
2023-02-09 | Journal article
DOI: 10.1093/g3journal/jkac307
Contributors: Sneha S Mokashi; Vijay Shankar; Joel A Johnstun; Trudy F C Mackay; Robert R H Anholt; S. Lott
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Natural Genetic Variation in a Dopamine Receptor is Associated With Variation in Female Fertility in Drosophila melanogaster

2022-09-06 | Preprint
DOI: 10.1101/2022.09.06.506722
Contributors: Richard F. Lyman; Rachel A. Lyman; Akihiko Yamamoto; Wen Huang; Susan T. Harbison; Shanshan Zhou; Robert R. H. Anholt; Trudy F. C. Mackay
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Gregor Mendel’s legacy in quantitative genetics

PLOS Biology
2022-07-19 | Journal article
DOI: 10.1371/journal.pbio.3001692
Contributors: Trudy F. C. Mackay; Robert R. H. Anholt
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Epistasis for head morphology in Drosophila melanogaster

G3 Genes|Genomes|Genetics
2021-09-27 | Journal article
DOI: 10.1093/g3journal/jkab285
Contributors: Ergi D Özsoy; Murat Yılmaz; Bahar Patlar; Güzin Emecen; Esra Durmaz; Michael M Magwire; Shanshan Zhou; Wen Huang; Robert R H Anholt; Trudy F C Mackay et al.
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Physiological and metabolomic consequences of reduced expression of the Drosophila brummer triglyceride Lipase

PLOS ONE
2021-09-21 | Journal article
DOI: 10.1371/journal.pone.0255198
Contributors: Nestor O. Nazario-Yepiz; Girish C. Melkani; Jaime Fernández Sobaberas; Roberta Lyman; Marion R. Campbell; Vijay Shankar; Robert R. H. Anholt; Trudy F. C. Mackay
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Physiological and Metabolomic Consequences of Reduced Expression of the Drosophila brummer Triglyceride Lipase

2021-08-04 | Other
DOI: 10.1101/2021.08.04.455099
Contributors: Nestor O. Nazario-Yepiz; Jaime Fernández Sobaberas; Roberta Lyman; Marion R. Campbell, III; Vijay Shankar; Robert R. H. Anholt; Trudy F. C. Mackay
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Genetic basis of variation in cocaine and methamphetamine consumption in outbred populations of Drosophila melanogaster

Proceedings of the National Academy of Sciences
2021-06-08 | Journal article
DOI: 10.1073/pnas.2104131118
Contributors: Brandon M. Baker; Mary Anna Carbone; Wen Huang; Robert R. H. Anholt; Trudy F. C. Mackay
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Heat shock proteins and small nucleolar RNAs are dysregulated in a Drosophila model for feline hypertrophic cardiomyopathy

G3 Genes|Genomes|Genetics
2021-03-10 | Journal article
DOI: 10.1093/g3journal/jkaa014
Contributors: Christian A Tallo; Laura H Duncan; Akihiko H Yamamoto; Joshua D Slaydon; Gunjan H Arya; Lavanya Turlapati; Trudy F C Mackay; Mary A Carbone; M Arbeitman
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Leveraging Multiple Layers of Data To Predict Drosophila Complex Traits

G3 Genes|Genomes|Genetics
2020-12-01 | Journal article
DOI: 10.1534/g3.120.401847
Contributors: Fabio Morgante; Wen Huang; Peter Sørensen; Christian Maltecca; Trudy F C Mackay
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Genetic Basis of Natural Variation in Spontaneous Grooming in Drosophila melanogaster

G3 Genes|Genomes|Genetics
2020-09-01 | Journal article
DOI: 10.1534/g3.120.401360
Contributors: Aya Yanagawa; Wen Huang; Akihiko Yamamoto; Ayako Wada-Katsumata; Coby Schal; Trudy F C Mackay
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Context-dependent genetic architecture of Drosophila life span

PLOS Biology
2020-03-05 | Journal article
DOI: 10.1371/journal.pbio.3000645
Contributors: Wen Huang; Nick H. Barton; Terry Campbell; Mary Anna Carbone; W. Elizabeth Jones; Desiree Unselt; Robert R. H. Anholt; Trudy F. C. Mackay
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Genetic Basis of Increased Lifespan and Postponed Senescence in Drosophila melanogaster

G3 Genes|Genomes|Genetics
2020-03-01 | Journal article
DOI: 10.1534/g3.120.401041
Contributors: Grace A Parker; Nathan Kohn; Ally Spirina; Anna McMillen; Wen Huang; Trudy F C Mackay
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Rapid and Predictable Evolution of Admixed Populations Between Two Drosophila Species Pairs

Genetics
2020-01-01 | Journal article
DOI: 10.1534/genetics.119.302685
Contributors: Daniel R Matute; Aaron A Comeault; Eric Earley; Antonio Serrato-Capuchina; David Peede; Anaïs Monroy-Eklund; Wen Huang; Corbin D Jones; Trudy F C Mackay; Jerry A Coyne
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Genetics of cocaine and methamphetamine consumption and preference in Drosophila melanogaster

PLOS Genetics
2019-05-20 | Journal article
DOI: 10.1371/journal.pgen.1007834
Contributors: Chad A. Highfill; David G. Heckel; Brandon M. Baker; Stephenie D. Stevens; Robert R. H. Anholt; Trudy F. C. Mackay
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Genetics of Cocaine and Methamphetamine Consumption and Preference in Drosophila melanogaster

2018-11-14 | Other
DOI: 10.1101/470906
Contributors: Chad A. Highfill; Brandon M. Baker; Stephenie D. Stevens; Robert R. H. Anholt; Trudy F. C. Mackay
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Charting the genotype–phenotype map: lessons from the Drosophila melanogaster Genetic Reference Panel

WIREs Developmental Biology
2018-01 | Journal article
DOI: 10.1002/wdev.289
Contributors: Trudy F.C. Mackay; Wen Huang
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A Drosophila model for toxicogenomics: Genetic variation in susceptibility to heavy metal exposure

PLOS Genetics
2017-07-21 | Journal article
DOI: 10.1371/journal.pgen.1006907
Contributors: Shanshan Zhou; Gregory P. Copenhaver; Sarah E. Luoma; Genevieve E. St. Armour; Esha Thakkar; Trudy F. C. Mackay; Robert R. H. Anholt
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Correction: Spontaneous mutations and the origin and maintenance of quantitative genetic variation

eLife
2016-10-19 | Journal article
DOI: 10.7554/eLife.22300
Contributors: Wen Huang; Richard F Lyman; Rachel A Lyman; Mary Anna Carbone; Susan T Harbison; Michael M Magwire; Trudy FC Mackay
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Spontaneous mutations and the origin and maintenance of quantitative genetic variation

eLife
2016-05-23 | Journal article
DOI: 10.7554/eLife.14625
Contributors: Wen Huang; Richard F Lyman; Rachel A Lyman; Mary Anna Carbone; Susan T Harbison; Michael M Magwire; Trudy FC Mackay
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