Personal information

Keywords

Cell biology, Malaria, Drug Resistance, Drug discovery, Genomics, Transcriptomics, Proteomics

Countries

United States, Singapore, Philippines

Biography

Molecular and Cell Biologist with a focus on drug discovery and drug resistance using multiomics approaches

Activities

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Employment (1)

University of California San Diego: La Jolla, CA, US

2018-05-01 to present | Postdoctoral Fellow (Department of Pediatrics, School of Medicine)
Employment
Source: Self-asserted source
Frances Rocamora

Education and qualifications (1)

Nanyang Technological University: Singapore, SG

2012-08-06 to 2017-06-10 | Doctor of Philosophy
Education
Source: Self-asserted source
Frances Rocamora

Works (13)

Glycoengineered recombinant alpha1-antitrypsin results in comparablein vitroandin vivoactivities to human plasma-derived protein

2024-03-30 | Preprint
DOI: 10.1101/2024.03.27.587088
Contributors: Frances Rocamora; Sanne Schoffelen; Johnny Arnsdorf; Eric A. Toth; Yunus Abdul; Thomas E. Cleveland, IV; Sara Petersen Bjørn; Mina Ying Min Wu; Noel G. McElvaney; Bjørn Gunnar Rude Voldborg et al.
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Crossref

Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases.

Journal of medicinal chemistry
2024-01-12 | Journal article
DOI: 10.1021/acs.jmedchem.3c02046
PMID: 38214254
Contributors: Lushun Wang; Monica Bohmer; Wang J; Nardella F; Calla J; Mariana Laureano de Souza; Schindler KA; Montejo L; Mittal N; Rocamora F et al.
Source: Self-asserted source
Frances Rocamora

Antiplasmodial peptaibols act through membrane directed mechanisms.

Cell chemical biology
2023-11-13 | Journal article
DOI: 10.1016/j.chembiol.2023.10.025
PMID: 37995692
Contributors: Collins JE; Lee JW; Rocamora F; Gagandeep Singh Saggu; Wendt KL; Pasaje CFA; Smick S; Santos NM; Paes R; Jiang T et al.
Source: Self-asserted source
Frances Rocamora

Glycosylation shapes the efficacy and safety of diverse protein, gene and cell therapies.

Biotechnology advances
2023-06-22 | Review
DOI: 10.1016/j.biotechadv.2023.108206
PMID: 37354999
Contributors: Rocamora F; Peralta AG; Shin S; Sorrentino J; Wu MYM; Toth EA; Fuerst TR; Lewis NE
Source: Self-asserted source
Frances Rocamora

Development of Potent and Highly Selective Epoxyketone‐Based Plasmodium Proteasome Inhibitors

Chemistry – A European Journal
2023-04-06 | Journal article
DOI: 10.1002/chem.202203958
Contributors: Jehad Almaliti; Pavla Fajtová; Jaeson Calla; Gregory M. LaMonte; Mudong Feng; Frances Rocamora; Sabine Ottilie; Evgenia Glukhov; Evzen Boura; Raymond T. Suhandynata et al.
Source: check_circle
Crossref

Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target

Science Translational Medicine
2023-03-08 | Journal article
DOI: 10.1126/scitranslmed.adc9249
Contributors: Eva S. Istvan; Francisco Guerra; Matthew Abraham; Kuo-Sen Huang; Frances Rocamora; Haoshuang Zhao; Lan Xu; Charisse Pasaje; Krittikorn Kumpornsin; Madeline R. Luth et al.
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Crossref

Development of Highly Selective Epoxyketone-based Plasmodium Proteasome Inhibitors with Negligible Cytotoxicity

2022-08-07 | Preprint
DOI: 10.1101/2022.08.06.502205
Contributors: Jehad Almaliti; Pavla Fajtová; Jaeson Calla; Gregory M. LaMonte; Mudong Feng; Frances Rocamora; Sabine Ottilie; Evgenia Glukhov; Evzen Boura; Raymond T. Suhandynata et al.
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Crossref

Semi-Synthetic Analogues of Cryptolepine as a Potential Source of Sustainable Drugs for the Treatment of Malaria, Human African Trypanosomiasis, and Cancer.

Frontiers in pharmacology
2022-04-26 | Journal article
DOI: 10.3389/fphar.2022.875647
PMID: 35600849
PMC: PMC9119314
Contributors: Abacha YZ; Forkuo AD; Gbedema SY; Mittal N; Ottilie S; Rocamora F; Winzeler EA; Donelly van Schalkwyk; Kelly JM; Taylor MC et al.
Source: Self-asserted source
Frances Rocamora

PfMFR3: A Multidrug-Resistant Modulator in <i>Plasmodium falciparum</i>.

ACS infectious diseases
2021-03-14 | Journal article
DOI: 10.1021/acsinfecdis.0c00676
PMID: 33715347
PMC: PMC8042660
Contributors: Rocamora F; Gupta P; Istvan ES; Luth MR; Carpenter EF; Kümpornsin K; Sasaki E; Calla J; Mittal N; Carolino K et al.
Source: Self-asserted source
Frances Rocamora

Genomic Approaches to Drug Resistance in Malaria.

Annual review of microbiology
2020-09-01 | Review
DOI: 10.1146/annurev-micro-012220-064343
PMID: 32905749
Contributors: Rocamora F; Elizabeth Winzeler
Source: Self-asserted source
Frances Rocamora

Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway

Nature Communications
2020-04-14 | Journal article
DOI: 10.1038/s41467-020-15440-4
Contributors: Gregory M. LaMonte; Frances Rocamora; Danushka S. Marapana; Nina F. Gnädig; Sabine Ottilie; Madeline R. Luth; Tilla S. Worgall; Gregory M. Goldgof; Roxanne Mohunlal; T. R. Santha Kumar et al.
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Crossref

The origins of malaria artemisinin resistance defined by a genetic and transcriptomic background.

Nature communications
2018-12-04 | Journal article
DOI: 10.1038/s41467-018-07588-x
PMID: 30514877
PMC: PMC6279830
Contributors: Zhu L; Tripathi J; Rocamora FM; Olivo Miotto; van der Pluijm R; Till S. Voss; Sachel Mok; Dominic Kwiatkowski; Francois Nosten; Day NPJ et al.
Source: Self-asserted source
Frances Rocamora

Oxidative stress and protein damage responses mediate artemisinin resistance in malaria parasites

PLOS Pathogens
2018-03-14 | Journal article
DOI: 10.1371/journal.ppat.1006930
Contributors: Frances Rocamora; Roland Cooper; Lei Zhu; Kek Yee Liong; Arjen Dondorp; Olivo Miotto; Sachel Mok; Zbynek Bozdech
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Crossref

Peer review (1 review for 1 publication/grant)

Review activity for Genome medicine. (1)
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