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Scopus Author ID: 7004509264

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École Polytechnique Fédérale de Lausanne: Lausanne, VD, CH

2005-01-01 to present | Professor (SV, ISREC)
Employment
Source: Self-asserted source
Joachim Lingner

Works (50 of 107)

Items per page:
Page 1 of 3

Oxidative stress at telomeres triggers internal DNA loops, TRF1 dissociation, and TRF2-dependent R-loops

Nucleic Acids Research
2025-04-10 | Journal article
DOI: 10.1093/nar/gkaf285
Contributors: Trang Thu Nguyen; Giulia Mazzucco; Eftychia Kyriacou; Thomas Lunardi; Leona Brandl; Wareed Ahmed; Ylli Doksani; Joachim Lingner
Source: check_circle
Crossref

TERRA R-loops trigger a switch in telomere maintenance towards break-induced replication and PrimPol-dependent repair

2025-01-10 | Preprint
DOI: 10.1101/2025.01.09.632133
Contributors: Suna In; Patricia Renck Nunes; Rita Valador Fernandes; Joachim Lingner
Source: check_circle
Crossref

TERRA long noncoding RNA: At the interphase of telomere damage, rescue and signaling

Current Opinion in Cell Biology
2024-12 | Journal article
DOI: 10.1016/j.ceb.2024.102437
Contributors: Eftychia Kyriacou; Joachim Lingner
Source: check_circle
Crossref

The THO complex counteracts TERRA R-loop-mediated telomere fragility in telomerase+ cells and telomeric recombination in ALT+ cells

Nucleic Acids Research
2023-07-21 | Journal article
DOI: 10.1093/nar/gkad448
Contributors: Rita Valador Fernandes; Joachim Lingner
Source: check_circle
Crossref

The human telomeric proteome during telomere replication

Nucleic Acids Research
2021-12-02 | Journal article
DOI: 10.1093/nar/gkab1015
Contributors: Chih-Yi Gabriela Lin; Anna Christina Näger; Thomas Lunardi; Aleksandra Vančevska; Gérald Lossaint; Joachim Lingner
Source: check_circle
Crossref

Challenging endings: How telomeres prevent fragility

BioEssays
2021-10 | Journal article
DOI: 10.1002/bies.202100157
Contributors: Galina Glousker; Joachim Lingner
Source: check_circle
Crossref

The makings of TERRA R-loops at chromosome ends

Cell Cycle
2021-09-17 | Journal article
DOI: 10.1080/15384101.2021.1962638
Contributors: Rita Valador Fernandes; Marianna Feretzaki; Joachim Lingner
Source: check_circle
Crossref

Human shelterin protein POT 1 prevents severe telomere instability induced by homology‐directed DNA repair

The EMBO Journal
2020-12 | Journal article
DOI: 10.15252/embj.2020104500
Contributors: Galina Glousker; Anna‐Sophia Briod; Manfredo Quadroni; Joachim Lingner
Source: check_circle
Crossref

RAD51-dependent recruitment of TERRA lncRNA to telomeres through R-loops

Nature
2020-11-12 | Journal article
DOI: 10.1038/s41586-020-2815-6
Contributors: Marianna Feretzaki; Michaela Pospisilova; Rita Valador Fernandes; Thomas Lunardi; Lumir Krejci; Joachim Lingner
Source: check_circle
Crossref

SMCHD 1 promotes ATM ‐dependent DNA damage signaling and repair of uncapped telomeres

The EMBO Journal
2020-04 | Journal article
DOI: 10.15252/embj.2019102668
Contributors: Aleksandra Vančevska; Wareed Ahmed; Verena Pfeiffer; Marianna Feretzaki; Simon J Boulton; Joachim Lingner
Source: check_circle
Crossref

Human POT1 Prevents Severe Telomere Instability Induced by Homology Directed DNA Repair

2020-01-20 | Preprint
DOI: 10.1101/2020.01.20.912642
Contributors: Galina Glousker; Anna-Sophia Briod; Manfredo Quadroni; Joachim Lingner
Source: check_circle
Crossref

RADX Sustains POT1 Function at Telomeres to Counteract RAD51 Binding, which Triggers Telomere Fragility

2020-01-20 | Preprint
DOI: 10.1101/2020.01.20.912634
Contributors: Anna-Sophia Briod; Galina Glousker; Joachim Lingner
Source: check_circle
Crossref

Expression and differential regulation of human TERRA at several chromosome ends

RNA
2019-11-26 | Journal article
DOI: 10.1261/rna.072322.119
Contributors: Marianna Feretzaki; Patricia Renck Nunes; Joachim Lingner
Source: check_circle
Crossref

SMCHD1 Promotes ATM-dependent DNA Damage Signaling and Repair of Uncapped Telomeres

2019-06-13 | Other
DOI: 10.1101/669119
Contributors: Aleksandra Vančevska; Verena Pfeiffer; Marianna Feretzaki; Wareed Ahmed; Joachim Lingner
Source: check_circle
Crossref

Transformation-induced stress at telomeres is counteracted through changes in the telomeric proteome including SAMHD1

Life Science Alliance
2018-08 | Journal article
DOI: 10.26508/lsa.201800121
Contributors: Jana Majerska; Marianna Feretzaki; Galina Glousker; Joachim Lingner
Source: check_circle
Crossref

PRDX1 and MTH1 cooperate to prevent ROS-mediated inhibition of telomerase

Genes & Development
2018-05-01 | Journal article
DOI: 10.1101/gad.313460.118
Contributors: Wareed Ahmed; Joachim Lingner
Source: check_circle
Crossref

A practical qPCR approach to detect TERRA, the elusive telomeric repeat-containing RNA

Methods
2017 | Journal article
DOI: 10.1016/j.ymeth.2016.08.004
EID:

2-s2.0-84995483180
Contributors: Feretzaki, M.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

Quantitative telomeric chromatin isolation protocol for human cells

Methods
2017 | Journal article
DOI: 10.1016/j.ymeth.2016.08.003
EID:

2-s2.0-84981743109
Contributors: Majerská, J.; Redon, S.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

TZAP or not to zap telomeres

Science
2017 | Journal article
DOI: 10.1126/science.aam7015
EID:

2-s2.0-85012082487
Contributors: Lossaint, G.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

Peroxiredoxin 1 Protects Telomeres from Oxidative Damage and Preserves Telomeric DNA for Extension by Telomerase

Cell Reports
2016 | Journal article
DOI: 10.1016/j.celrep.2016.11.071
EID:

2-s2.0-85006759590
Contributors: Aeby, E.; Ahmed, W.; Redon, S.; Simanis, V.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

ALT telomeres get together with nuclear receptors

Cell
2015 | Journal article
DOI: 10.1016/j.cell.2015.02.006
EID:

2-s2.0-84923349063
Contributors: Aeby, E.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

Telomere functions grounding on TERRA firma

Trends in Cell Biology
2015 | Journal article
DOI: 10.1016/j.tcb.2014.08.007
EID:

2-s2.0-84918549784
Contributors: Azzalin, C.M.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

Functional characterization of the TERRA transcriptome at damaged telomeres

Nature Communications
2014 | Journal article
DOI: 10.1038/ncomms6379
EID:

2-s2.0-84923355398
Contributors: Porro, A.; Feuerhahn, S.; Delafontaine, J.; Riethman, H.; Rougemont, J.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

TERRA-Reinforced Association of LSD1 with MRE11 Promotes Processing of Uncapped Telomeres

Cell Reports
2014 | Journal article
DOI: 10.1016/j.celrep.2014.01.022
EID:

2-s2.0-84896730316
Contributors: Porro, A.; Feuerhahn, S.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

The shelterin component TPP1 is a binding partner and substrate for the deubiquitinating enzyme USP7

Journal of Biological Chemistry
2014 | Journal article
DOI: 10.1074/jbc.M114.596056
EID:

2-s2.0-84907610570
Contributors: Zemp, I.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

A quantitative telomeric chromatin isolation protocol identifies different telomeric states

Nature Communications
2013 | Journal article
DOI: 10.1038/ncomms3848
EID:

2-s2.0-84889056254
Contributors: Grolimund, L.; Aeby, E.; Hamelin, R.; Armand, F.; Chiappe, D.; Moniatte, M.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

A three-state model for the regulation of telomerase by TERRA and hnRNPA1

Nucleic Acids Research
2013 | Journal article
DOI: 10.1093/nar/gkt695
EID:

2-s2.0-84886051117
Contributors: Redon, S.; Zemp, I.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

CST for the grand finale of telomere replication

Nucleus
2013 | Journal article
DOI: 10.4161/nucl.25701
EID:

2-s2.0-84908016494
Contributors: Chen, L.-Y.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

CST for the grand finale of telomere replication

Nucleus (United States)
2013 | Journal article
EID:

2-s2.0-84881231304
Contributors: Chen, L.-Y.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

Molecular basis of telomere syndrome caused by CTC1 mutations

Genes and Development
2013 | Journal article
DOI: 10.1101/gad.222893.113
EID:

2-s2.0-84885347329
Contributors: Chen, L.-Y.; Majerská, J.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

Replication of telomeres and the regulation of telomerase

Cold Spring Harbor Perspectives in Biology
2013 | Journal article
DOI: 10.1101/cshperspect.a010405
EID:

2-s2.0-84877102552
Contributors: Pfeiffer, V.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

Replication of telomeres and the regulation of telomerase.

Cold Spring Harbor perspectives in biology
2013 | Journal article
EID:

2-s2.0-84891646331
Contributors: Pfeiffer, V.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

Structure of active dimeric human telomerase

Nature Structural and Molecular Biology
2013 | Journal article
DOI: 10.1038/nsmb.2530
EID:

2-s2.0-84876170469
Contributors: Sauerwald, A.; Sandin, S.; Cristofari, G.; Scheres, S.H.W.; Lingner, J.; Rhodes, D.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

Telomerase inhibitors from cyanobacteria: Isolation and synthesis of sulfoquinovosyl diacylglycerols from Microcystis aeruguinosa PCC 7806

Chemistry - A European Journal
2013 | Journal article
DOI: 10.1002/chem.201203296
EID:

2-s2.0-84875294755
Contributors: Brahmi, M.M.; Portmann, C.; D'Ambrosio, D.; Woods, T.M.; Banfi, D.; Reichenbach, P.; Da Silva, L.; Baudat, E.; Turcatti, G.; Lingner, J. et al.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

Telomere length homeostasis responds to changes in intracellular dNTP pools

Genetics
2013 | Journal article
DOI: 10.1534/genetics.112.149120
EID:

2-s2.0-84876362282
Contributors: Gupta, A.; Sharma, S.; Reichenbach, P.; Marjavaara, L.; Nilsson, A.K.; Lingner, J.; Chabes, A.; Rothstein, R.; Chang, M.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

The THO complex component Thp2 counteracts telomeric R-loops and telomere shortening

EMBO Journal
2013 | Journal article
DOI: 10.1038/emboj.2013.217
EID:

2-s2.0-84887053583
Contributors: Pfeiffer, V.; Crittin, J.; Grolimund, L.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

AUF1/HnRNP D RNA Binding Protein Functions in Telomere Maintenance

Molecular Cell
2012 | Journal article
DOI: 10.1016/j.molcel.2012.06.031
EID:

2-s2.0-84863817688
Contributors: Chen, L.-Y.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

Specific binding of telomeric G-quadruplexes by hydrosoluble perylene derivatives inhibits repeat addition processivity of human telomerase

Biochimie
2012 | Journal article
DOI: 10.1016/j.biochi.2011.12.004
EID:

2-s2.0-84857038475
Contributors: D'Ambrosio, D.; Reichenbach, P.; Micheli, E.; Alvino, A.; Franceschin, M.; Savino, M.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

Telomerase Regulation and Telomere-Length Homeostasis

Telomerases: Chemistry, Biology, and Clinical Applications
2012 | Book
DOI: 10.1002/9781118268667.ch6
EID:

2-s2.0-84886158325
Contributors: Lingner, J.; Shore, D.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

TERRA promotes telomere shortening through exonuclease 1-mediated resection of chromosome ends

PLoS Genetics
2012 | Journal article
DOI: 10.1371/journal.pgen.1002747
EID:

2-s2.0-84864041566
Contributors: Pfeiffer, V.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

The human CST complex is a terminator of telomerase activity

Nature
2012 | Journal article
DOI: 10.1038/nature11269
EID:

2-s2.0-84865263603
Contributors: Chen, L.-Y.; Redon, S.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

Subtelomeric repetitive elements determine TERRA regulation by Rap1/Rif and Rap1/Sir complexes in yeast

EMBO Reports
2011 | Journal article
DOI: 10.1038/embor.2011.73
EID:

2-s2.0-79957983472
Contributors: Iglesias, N.; Redon, S.; Pfeiffer, V.; Dees, M.; Lingner, J.; Luke, B.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast

Nature Cell Biology
2011 | Journal article
DOI: 10.1038/ncb2263
EID:

2-s2.0-79960004074
Contributors: Ferreira, H.C.; Luke, B.; Schober, H.; Kalck, V.; Lingner, J.; Gasser, S.M.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

Molecular dissection of telomeric repeat-containing RNA biogenesis unveils the presence of distinct and multiple regulatory pathways

Molecular and Cellular Biology
2010 | Journal article
DOI: 10.1128/MCB.00460-10
EID:

2-s2.0-78049386911
Contributors: Porro, A; Feuerhahn, S.; Reichenbach, P.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

TERRA biogenesis, turnover and implications for function

FEBS Letters
2010 | Journal article
DOI: 10.1016/j.febslet.2010.07.032
EID:

2-s2.0-77955844757
Contributors: Feuerhahn, S.; Iglesias, N.; Panza, A.; Porro, A.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase

Nucleic Acids Research
2010 | Journal article
DOI: 10.1093/nar/gkq296
EID:

2-s2.0-77957243987
Contributors: Redon, S.; Reichenbach, P.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo

Molecular and Cellular Biology
2010 | Journal article
DOI: 10.1128/MCB.00240-10
EID:

2-s2.0-77953427257
Contributors: Abreu, E.; Aritonovska, E.; Reichenbach, P.; Cristofari, G.; Culp, B.; Terns, R.M.; Lingner, J.; Terns, M.P.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

Related Mechanisms for End Processing at Telomeres and DNA Double-Strand Breaks

Molecular Cell
2009 | Journal article
DOI: 10.1016/j.molcel.2009.07.007
EID:

2-s2.0-67651087281
Contributors: Iglesias, N.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

Telomerase is essential to alleviate Pif1-induced replication stress at telomeres

Genetics
2009 | Journal article
DOI: 10.1534/genetics.109.107631
EID:

2-s2.0-72449150129
Contributors: Chang, M.; Luke, B.; Kraft, C.; Li, Z.; Peter, M.; Lingner, J.; Rothstein, R.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier

TERRA: Telomeric repeat-containing RNA

EMBO Journal
2009 | Journal article
DOI: 10.1038/emboj.2009.166
EID:

2-s2.0-69849104275
Contributors: Luke, B.; Lingner, J.
Source: Self-asserted source
Joachim Lingner via Scopus - Elsevier
Items per page:
Page 1 of 3

Peer review (3 reviews for 1 publication/grant)

Review activity for Nature (3)
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