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Keywords

Protein-Protein interactions, Type I interferon

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Israel

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Employment (1)

Weizmann Institute of Science: Rehovot, IL

1996 to present | Professor (Biological Chemistry)
Employment
Source: Self-asserted source
Gideon Schreiber

Education and qualifications (1)

Hebrew University of Jerusalem: Jerusalem, Jerusalem, IL

1980 to 1992
Education
Source: Self-asserted source
Gideon Schreiber

Works (23)

Reversing protonation of weakly basic drugs greatly enhances intracellular diffusion and decreases lysosomal sequestration

eLife
2024-12-06 | Journal article
DOI: 10.7554/eLife.97255.3
Contributors: Debabrata Dey; Shir Marciano; Anna Poryval; Ondřej Groborz; Lucie Wohlrabova; Tomás Slanina; Gideon Schreiber
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Crossref

Reversing protonation of weakly basic drugs greatly enhances intracellular diffusion and decreases lysosomal sequestration

eLife
2024-12-06 | Journal article
DOI: 10.7554/eLife.97255
Contributors: Debabrata Dey; Shir Marciano; Anna Poryval; Ondřej Groborz; Lucie Wohlrabova; Tomás Slanina; Gideon Schreiber
Source: check_circle
Crossref

Promiscuous Janus kinase binding to cytokine receptors modulates signaling efficiencies and contributes to cytokine pleiotropy

Science Signaling
2024-11-19 | Journal article
DOI: 10.1126/scisignal.adl1892
Contributors: Eyal Zoler; Thomas Meyer; Junel Sotolongo Bellón; Mia Mönnig; Boyue Sun; Jacob Piehler; Gideon Schreiber
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Crossref

Reversing protonation of weakly basic drugs greatly enhances intracellular diffusion and decreases lysosomal sequestration

2024-11-15 | Preprint
DOI: 10.7554/eLife.97255.2
Contributors: Debabrata Dey; Shir Marciano; Anna Poryvai; Ondřej Groborz; Lucie Wohlrábová; Tomás Slanina; Gideon Schreiber
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Crossref

Reversing protonation of weakly basic drugs greatly enhances intracellular diffusion and decreases lysosomal sequestration

2024-06-14 | Preprint
DOI: 10.7554/eLife.97255.1
Contributors: Debabrata Dey; Shir Marciano; Anna Poryvai; Ondřej Groborz; Lucie Wohlrábová; Tomás Slanina; Gideon Schreiber
Source: check_circle
Crossref

Harnessing the power of IFN for therapeutic approaches to COVID-19

Journal of Virology
2024-05-14 | Journal article
DOI: 10.1128/jvi.01204-23
Contributors: Elise G. Viox; Steven E. Bosinger; Daniel C. Douek; Gideon Schreiber; Mirko Paiardini; David E. Levy
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Crossref

Specificity and promiscuity of JAK recruitment regulates pleiotropy of cytokine-receptor signaling

2023-10-04 | Preprint
DOI: 10.1101/2023.10.04.560821
Contributors: Eyal Zoler; Thomas Meyer; Junel Sotolongo Bellón; Boyue Sun; Jacob Piehler; Gideon Schreiber
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Crossref

Reversing protonation of weakly basic drugs greatly enhances intracellular diffusion and decreases lysosomal sequestration

2023-04-21 | Preprint
DOI: 10.1101/2023.04.19.537456
Contributors: Debabrata Dey; Shir Marciano; Anna Poryvai; Ondřej Groborz; Lucie Wohlrábová; Tomás Slanina; Gideon Schreiber
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Crossref

Diffusion of small molecule drugs is affected by surface interactions and crowder proteins

iScience
2022-10 | Journal article
DOI: 10.1016/j.isci.2022.105088
Contributors: Debabrata Dey; Ariane Nunes-Alves; Rebecca C. Wade; Gideon Schreiber
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Crossref

Genetically Engineered MRI-Trackable Extracellular Vesicles as SARS-CoV-2 Mimetics for Mapping ACE2 Binding In Vivo

ACS Nano
2022-08-23 | Journal article
DOI: 10.1021/acsnano.2c03119
Contributors: Andrea Galisova; Jiri Zahradnik; Hyla Allouche-Arnon; Mattia I. Morandi; Paula Abou Karam; Michal Fisler; Ori Avinoam; Neta Regev-Rudzki; Gideon Schreiber; Amnon Bar-Shir
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Crossref

In vitro Evolution of Uracil Glycosylase Towards DnaKJ and GroEL Binding Evolves Different Misfolded States

Journal of Molecular Biology
2022-07 | Journal article
DOI: 10.1016/j.jmb.2022.167627
Contributors: Oran Melanker; Pierre Goloubinoff; Gideon Schreiber
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Crossref

Gelatin Stabilizes Nebulized Proteins in Pulmonary Drug Delivery against COVID-19

ACS Biomaterials Science & Engineering
2022-06-13 | Journal article
DOI: 10.1021/acsbiomaterials.2c00419
Contributors: Chunlin Li; Ira Marton; Daniel Harari; Maya Shemesh; Vyacheslav Kalchenko; Michal Pardo; Gideon Schreiber; Yinon Rudich
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Crossref

De novo developed protein binders mimicking Interferon lambda signaling

The FEBS Journal
2022-05 | Journal article
DOI: 10.1111/febs.16300
Contributors: Lucie Kolářová; Jiří Zahradník; Maroš Huličiak; Pavel Mikulecký; Yoav Peleg; Maya Shemesh; Gideon Schreiber; Bohdan Schneider
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Crossref

A Protein-Engineered, Enhanced Yeast Display Platform for Rapid Evolution of Challenging Targets

ACS Synthetic Biology
2021-12-17 | Journal article
DOI: 10.1021/acssynbio.1c00395
Contributors: Jiří Zahradník; Debabrata Dey; Shir Marciano; Lucie Kolářová; Chloé I. Charendoff; Agathe Subtil; Gideon Schreiber
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Crossref

In vitro evolution of uracil glycosylase towards DnaKJ and GroEL binding evolves different misfolded states

2021-12-01 | Preprint
DOI: 10.1101/2021.11.30.470542
Contributors: Oran Melanker; Pierre Goloubinoff; Gideon Schreiber
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Crossref

IFNAR1 and IFNAR2 play distinct roles in initiating type I interferon–induced JAK-STAT signaling and activating STATs

Science Signaling
2021-11-23 | Journal article
DOI: 10.1126/scisignal.abe4627
Contributors: Maya Shemesh; Sara Lochte; Jacob Piehler; Gideon Schreiber
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Crossref

Protein Engineering in the Design of Protein–Protein Interactions: SARS-CoV-2 Inhibitors as a Test Case

Biochemistry
2021-11-23 | Journal article
DOI: 10.1021/acs.biochem.1c00356
Contributors: Jiří Zahradník; Gideon Schreiber
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Crossref

SARS-CoV-2 convergent evolution as a guide to explore adaptive advantage

2021-05-25 | Other
DOI: 10.1101/2021.05.24.445534
Contributors: Jiří Zahradník; Jaroslav Nunvar; Gideon Schreiber
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Crossref

SARS-CoV-2 RBD in vitro evolution parrots and predicts contagious mutation spread

2021-02-05 | Preprint
DOI: 10.21203/rs.3.rs-183310/v1
Contributors: Gideon Schreiber; Jiri Zahradník; Shir Marciano; Maya Shemesh; Eyal Zoler; Jeanne Chiaravalli; Bjoern Meyer; Yinon Rudich; Orly Dym; Nadav Elad
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Crossref

SARS-CoV-2 RBD in vitro evolution follows contagious mutation spread, yet generates an able infection inhibitor

2021-01-06 | Other
DOI: 10.1101/2021.01.06.425392
Contributors: Jiří Zahradník; Shir Marciano; Maya Shemesh; Eyal Zoler; Jeanne Chiaravalli; Björn Meyer; Yinon Rudich; Orly Dym; Nadav Elad; Gideon Schreiber
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Crossref

An enhanced yeast display platform demonstrates the binding plasticity under various selection pressures

2020-12-17 | Preprint
DOI: 10.1101/2020.12.16.423176
Contributors: Jiří Zahradník; Debabrata Dey; Shir Marciano; Gideon Schreiber
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Crossref

Line-FRAP, a versatile method based on fluorescence recovery after photobleaching to measure diffusion ratesin vitroandin vivo

2020-07-02 | Preprint
DOI: 10.1101/2020.07.01.181750
Contributors: Debabrata Dey; Shir Marciano; Gideon Schreiber
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Crossref

Selecting for Fast Protein–Protein Association As Demonstrated on a Random TEM1 Yeast Library Binding BLIP

Biochemistry
2018-08-07 | Journal article
DOI: 10.1021/acs.biochem.8b00172
Contributors: Ruth Cohen-Khait; Gideon Schreiber
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Crossref
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