Personal information

No personal information available

Activities

Collapse all

Employment (1)

Charles University, 1st Faculty of Medicine: Prague, CZ

Head/Professor (Institute of Biochemistry and Experimental Oncology)
Employment
Source: Self-asserted source
Aleksi Sedo

Education and qualifications (1)

Univerzita Karlova v Praze 1 lekarska fakulta: Praha, CZ

1980-09-01 to 1986-06-15
Education
Source: Self-asserted source
Aleksi Sedo

Works (50 of 77)

Items per page:
Page 1 of 2

Microtubule‐associated NAV3 regulates invasive phenotypes in glioblastoma cells

Brain Pathology
2025-01 | Journal article
DOI: 10.1111/bpa.13294
Contributors: Aneta Škarková; Markéta Pelantová; Ondřej Tolde; Anna Legátová; Rosana Mateu; Petr Bušek; Elena Garcia‐Borja; Aleksi Šedo; Sandrine Etienne‐Manneville; Daniel Rösel et al.
Source: check_circle
Crossref

Does DPP-IV Inhibition Offer New Avenues for Therapeutic Intervention in Malignant Disease?

Cancers
2022-04-21 | Journal article
DOI: 10.3390/cancers14092072
Contributors: Petr Busek; Jonathan S. Duke-Cohan; Aleksi Sedo
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Fibroblast Activation Protein Expressing Mesenchymal Cells Promote Glioblastoma Angiogenesis

Cancers
2021-07 | Journal article | Author
DOI: 10.3390/cancers13133304
Contributors: Eva Balaziova; Petr Vymola; Petr Hrabal; Rosana Mateu; Michal Zubaľ; Robert Tomáš; David Netuka; Filip Kramar; Zuzana Zemanova; Karla Svobodova et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

Regulation of Fibroblast Activation Protein by Transforming Growth Factor Beta-1 in Glioblastoma Microenvironment.

International journal of molecular sciences
2021-01 | Journal article
DOI: 10.3390/ijms22031046
PMID: 33494271
PMC: PMC7864518
Contributors: Krepela E; Vanickova Z; Hrabal P; Zubal M; Chmielova B; Balaziova E; Vymola P; Matrasova I; Busek P; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Molecular recognition of fibroblast activation protein for diagnostic and therapeutic applications.

Biochimica et biophysica acta. Proteins and proteomics
2020-04 | Journal article
DOI: 10.1016/j.bbapap.2020.140409
PMID: 32171757
Contributors: Šimková A; Bušek P; Šedo A; Konvalinka J
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

P11.41 Comparison of fibroblast activation protein expression and localization in glioblastomas and brain metastases

Neuro-oncology
2019-09 | Journal article
PMC: PMC6796117
Contributors: Busek P; Zubal M; Chmielova B; Vanickova Z; Hrabal P; Krepela E; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

P04.28 Effect of fibroblast activation protein-expressing stromal cells from human glioblastomas on glioma and endothelial cells

Neuro-oncology
2018-09 | Journal article
PMC: PMC6144288
Contributors: Busek P; Balaziova E; Mateu R; Vymola P; Vlasicova K; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Targeting fibroblast activation protein in cancer - Prospects and caveats.

Frontiers in bioscience (Landmark edition)
2018-06 | Journal article
DOI: 10.2741/4682
PMID: 29772538
Contributors: Busek P; Mateu R; Zubal M; Kotackova L; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Fibroblasts potentiate melanoma cells in vitro invasiveness induced by UV-irradiated keratinocytes.

Histochemistry and cell biology
2018-02 | Journal article
DOI: 10.1007/s00418-018-1650-4
PMID: 29435761
Contributors: Jobe NP; Živicová V; Mifková A; Rösel D; Dvořánková B; Kodet O; Strnad H; Kolář M; Šedo A; Smetana K et al.
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Identification of microRNAs differentially expressed in glioblastoma stem-like cells and their association with patient survival.

Scientific reports
2018-02 | Journal article
DOI: 10.1038/s41598-018-20929-6
PMID: 29434344
PMC: PMC5809429
Contributors: Sana J; Busek P; Fadrus P; Besse A; Radova L; Vecera M; Reguli S; Stollinova Sromova L; Hilser M; Lipina R et al.
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Inhibitor-Decorated Polymer Conjugates Targeting Fibroblast Activation Protein.

Journal of medicinal chemistry
2017-10 | Journal article
DOI: 10.1021/acs.jmedchem.7b00767
PMID: 28953383
Contributors: Dvořáková P; Bušek P; Knedlík T; Schimer J; Etrych T; Kostka L; Stollinová Šromová L; Šubr V; Šácha P; Šedo A et al.
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Species-specific real-time RT-PCR analysis of expression of stromal cell genes in a tumor xenotransplantation model in mice

Biochemical and Biophysical Research Communications
2017-09 | Journal article
DOI: 10.1016/j.bbrc.2017.07.061
Contributors: Evzen Krepela; Petr Busek; Marek Hilser; Zdislava Vanickova; Aleksi Sedo
Source: check_circle
Crossref

Early detection of sporadic pancreatic cancer: time for change.

European journal of gastroenterology & hepatology
2017-08 | Journal article
DOI: 10.1097/meg.0000000000000904
PMID: 28471824
Contributors: Frič P; Šedo A; Škrha J; Bušek P; Laclav M; Škrha P; Zavoral M
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Heterogeneity of molecular forms of dipeptidyl peptidase-IV and fibroblast activation protein in human glioblastomas.

Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia
2017-04 | Journal article
DOI: 10.5507/bp.2017.010
PMID: 28452380
Contributors: Matrasova I; Busek P; Balaziova E; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Precursors of pancreatic cancer.

European journal of gastroenterology & hepatology
2017-03 | Journal article
DOI: 10.1097/meg.0000000000000810
PMID: 28009716
Contributors: Frič P; Škrha J; Šedo A; Bušek P; Laclav M; Bunganič B; Zavoral M
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Early detection of pancreatic cancer: impact of high-resolution imaging methods and biomarkers.

European journal of gastroenterology & hepatology
2016-12 | Journal article
DOI: 10.1097/meg.0000000000000727
PMID: 27769077
Contributors: Frič P; Škrha J; Šedo A; Zima T; Bušek P; Kmochová K; Laclav M; Bunganič B; Solař S; Hrabal P et al.
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Intercellular crosstalk in human malignant melanoma.

Protoplasma
2016-11 | Journal article
DOI: 10.1007/s00709-016-1038-z
PMID: 27807664
Contributors: Dvořánková B; Szabo P; Kodet O; Strnad H; Kolář M; Lacina L; Krejčí E; Naňka O; Šedo A; Smetana K
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Ageing as an Important Risk Factor for Cancer.

Anticancer research
2016-10 | Journal article
DOI: 10.21873/anticanres.11069
PMID: 27798859
Contributors: Smetana K; Lacina L; Szabo P; Dvořánková B; Brož P; Šedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

P06.07 Fibroblast activation protein alpha is expressed by transformed and stromal cells and is associated with mesenchymal features in glioblastoma

Neuro-oncology
2016-09 | Journal article
PMC: PMC5782596
Contributors: Busek P; Balaziova E; Matrasova I; Hilser M; Tomas R; Syrucek M; Zemanova Z; Krepela E; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Fibroblast activation protein alpha is expressed by transformed and stromal cells and is associated with mesenchymal features in glioblastoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
2016-08 | Journal article
DOI: 10.1007/s13277-016-5274-9
PMID: 27492457
Contributors: Busek P; Balaziova E; Matrasova I; Hilser M; Tomas R; Syrucek M; Zemanova Z; Krepela E; Belacek J; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Early pancreatic carcinogenesis - risk factors, early symptoms, and the impact of antidiabetic drugs.

European journal of gastroenterology & hepatology
2016-07 | Journal article
DOI: 10.1097/meg.0000000000000646
PMID: 27120389
Contributors: Frič P; Škrha J; Šedo A; Bušek P; Kmochová K; Laclav M; Solař S; Bunganič B; Zavoral M
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Dynamic Change of Focal Fatty Sparing in Non-Alcoholic Fatty Liver Disease after Treatment with Sitagliptin.

Ultrasound international open
2016-06 | Journal article
DOI: 10.1055/s-0036-1582302
PMID: 27689184
PMC: PMC5026043
Contributors: Hoffmanová I; Škrha P; Šedo A; Anděl M
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Increased tissue and circulating levels of dipeptidyl peptidase-IV enzymatic activity in patients with pancreatic ductal adenocarcinoma.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
2016-06 | Journal article
DOI: 10.1016/j.pan.2016.06.001
PMID: 27320722
Contributors: Busek P; Vanickova Z; Hrabal P; Brabec M; Fric P; Zavoral M; Skrha J; Kmochova K; Laclav M; Bunganic B et al.
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

[Annual monitoring of side effects of administering sitagliptin in patients with type 2 diabetes mellitus].

Vnitrni lekarstvi
2016-01 | Journal article
PMID: 27485843
Contributors: Andel M; Skrha P; Kraml P; Potockova J; Hoffmanova I; Silhova E; Fontana J; Richterova A; Gadiredi M; Busek P et al.
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

[Early detection of sporadic pancreatic cancer].

Casopis lekaru ceskych
2016-01 | Journal article
PMID: 26898791
Contributors: Frič P; Šedo A; Škrha J; Zima T; Bušek P; Škrha P; Kmochová K; Laclav M; Bunganič B; Zavoral M
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Intraindividual changes of dipeptidyl peptidase-IV in peripheral blood of patients with rheumatoid arthritis are associated with the disease activity.

BMC musculoskeletal disorders
2015-09 | Journal article
DOI: 10.1186/s12891-015-0707-y
PMID: 26353808
PMC: PMC4564966
Contributors: Sromova L; Busek P; Sedova L; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Effect of cancer-associated fibroblasts on the migration of glioma cells in vitro.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
2015-02 | Journal article
DOI: 10.1007/s13277-015-3259-8
PMID: 25712375
Contributors: Trylcova J; Busek P; Smetana K; Balaziova E; Dvorankova B; Mifkova A; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Co-expression of the homologous proteases fibroblast activation protein and dipeptidyl peptidase-IV in the adult human Langerhans islets.

Histochemistry and cell biology
2014-11 | Journal article
DOI: 10.1007/s00418-014-1292-0
PMID: 25361590
Contributors: Busek P; Hrabal P; Fric P; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

P01.01EXPRESSION OF FIBROBLAST ACTIVATION PROTEIN ALPHA IN HUMAN HIGH-GRADE GLIOMAS

Neuro-oncology
2014-09 | Journal article
PMC: PMC4185866
Contributors: Balaziova E; Busek P; Hilser M; Vomelova I; Sromova L; Krepela E; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Compartment- and malignance-dependent up-regulation of γ-glutamyltranspeptidase and dipetidylpeptidase-IV activity in human brain gliomas.

Histology and histopathology
2012-07 | Journal article
DOI: 10.14670/hh-27.931
PMID: 22648548
Contributors: Mareš V; Stremeňová J; Lisá V; Kozáková H; Marek J; Syrůček M; Šoula O; Šedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Dipeptidyl peptidase-IV inhibits glioma cell growth independent of its enzymatic activity.

The international journal of biochemistry & cell biology
2012-01 | Journal article
DOI: 10.1016/j.biocel.2012.01.011
PMID: 22306301
Contributors: Busek P; Stremenova J; Sromova L; Hilser M; Balaziova E; Kosek D; Trylcova J; Strnad H; Krepela E; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Limitations of macroscopic fluorescence imaging for the estimation of tumour growth in an orthotopic glioma mouse model.

Folia biologica
2012-01 | Journal article
PMID: 22849863
Contributors: Hilšer M; Trylčová J; Bušek P; Šedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Coupled expression of dipeptidyl peptidase-IV and fibroblast activation protein-α in transformed astrocytic cells.

Molecular and cellular biochemistry
2011-04 | Journal article
DOI: 10.1007/s11010-011-0828-z
PMID: 21526345
Contributors: Balaziova E; Busek P; Stremenova J; Sromova L; Krepela E; Lizcova L; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Dipeptidyl peptidase-IV in synovial fluid and in synovial fluid mononuclear cells of patients with rheumatoid arthritis.

Clinica chimica acta; international journal of clinical chemistry
2010-03 | Journal article
DOI: 10.1016/j.cca.2010.03.034
PMID: 20361950
Contributors: Sromova L; Mareckova H; Sedova L; Balaziova E; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Inhibition of multifunctional dipeptidyl peptidase-IV: is there a risk of oncological and immunological adverse effects?

Diabetes research and clinical practice
2010-03 | Journal article
DOI: 10.1016/j.diabres.2010.02.017
PMID: 20303610
Contributors: Stulc T; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Expression of dipeptidyl peptidase-IV activity and/or structure homologs in human meningiomas.

International journal of oncology
2010-02 | Journal article
PMID: 20043068
Contributors: Stremenová J; Mares V; Lisá V; Hilser M; Krepela E; Vanicková Z; Syrucek M; Soula O; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Expression pattern of dipeptidyl peptidase IV activity and/or structure homologues in cancer.

Folia biologica
2009-01 | Journal article
PMID: 19545486
Contributors: Kotacková L; Baláziová E; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Methods of RNA purification. All ways (should) lead to Rome.

Folia biologica
2009-01 | Journal article
PMID: 20163774
Contributors: Vomelová I; Vanícková Z; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Dipeptidyl peptidase-IV and related molecules: markers of malignancy?

Expert opinion on medical diagnostics
2008-06 | Journal article
DOI: 10.1517/17530059.2.6.677
PMID: 23495778
Contributors: Sedo A; Stremenová J; Bušek P; Duke-Cohan JS
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Dipeptidyl peptidase-IV enzymatic activity bearing molecules in human brain tumors--good or evil?

Frontiers in bioscience : a journal and virtual library
2008-01 | Journal article
DOI: 10.2741/2846
PMID: 17981714
Contributors: Busek P; Stremenova J; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Expression and enzymatic activity of dipeptidyl peptidase-IV in human astrocytic tumours are associated with tumour grade.

International journal of oncology
2007-10 | Journal article
PMID: 17786309
Contributors: Stremenova J; Krepela E; Mares V; Trim J; Dbaly V; Marek J; Vanickova Z; Lisa V; Yea C; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Modulation of substance P signaling by dipeptidyl peptidase-IV enzymatic activity in human glioma cell lines.

Physiological research
2007-10 | Journal article
DOI: 10.33549/physiolres.931231
PMID: 17949241
Contributors: Busek P; Stremeňová J; Krepela E; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Dipeptidyl peptidase-IV activity and/or structure homologs (DASH): contributing factors in the pathogenesis of rheumatic diseases?

Advances in experimental medicine and biology
2006-01 | Journal article
DOI: 10.1007/0-387-32824-6_18
PMID: 16700520
Contributors: Balaziova E; Sedova L; Mares V; Vlasicova K; Sevcik J; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Expression and function of dipeptidyl peptidase IV and related enzymes in cancer.

Advances in experimental medicine and biology
2006-01 | Journal article
DOI: 10.1007/0-387-32824-6_6
PMID: 16700508
Contributors: Busek P; Krepela E; Mares V; Vlasicova K; Sevcik J; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Dipeptidyl peptidase IV activity and/or structure homologs: contributing factors in the pathogenesis of rheumatoid arthritis?

Arthritis research & therapy
2005-10 | Journal article
DOI: 10.1186/ar1852
PMID: 16277701
PMC: PMC1297595
Contributors: Sedo A; Duke-Cohan JS; Balaziova E; Sedova LR
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Up-regulation of gamma-glutamyl transpeptidase (GGT) activity in growth perturbed C6 astrocytes.

Brain research. Molecular brain research
2005-03 | Journal article
DOI: 10.1016/j.molbrainres.2005.01.007
PMID: 15893589
Contributors: Mares V; Malík R; Lisá V; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

'Dipeptidyl peptidase-IV activity and/or structure homologs' (DASH) in growth-modulated glioma cell lines.

Biological chemistry
2004-06 | Journal article
DOI: 10.1515/bc.2004.067
PMID: 15255190
Contributors: Sedo A; Busek P; Scholzová E; Malík R; Vlasicová K; Janácková S; Mares V
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Detection of cell type and marker specificity of nuclear binding sites for anionic carbohydrate ligands.

Biotechnic & histochemistry : official publication of the Biological Stain Commission
2004-06 | Journal article
DOI: 10.1080/10520290400011554
PMID: 15621886
Contributors: Chovanec M; Smetana K; Purkrábková T; Holíková Z; Dvoránková B; André S; Pytlík R; Hozák P; Plzák J; Sedo A et al.
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Dipeptidyl peptidase IV activity and/or structure homologues (DASH) and their substrates in cancer.

The international journal of biochemistry & cell biology
2004-03 | Journal article
DOI: 10.1016/s1357-2725(03)00262-0
PMID: 14687920
Contributors: Busek P; Malík R; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central

Cisplatin induced gamma-glutamyltransferase up-regulation, hypertrophy and differentiation in astrocytic glioma cells in culture.

Histology and histopathology
2003-07 | Journal article
DOI: 10.14670/hh-18.687
PMID: 12792879
Contributors: Mares V; Lisá V; Malík R; Kozáková H; Sedo A
Source: Self-asserted source
Aleksi Sedo via Europe PubMed Central
Items per page:
Page 1 of 2

Peer review (3 reviews for 3 publications/grants)

Review activity for iScience. (1)
Review activity for Life sciences. (1)
Review activity for Pharmacological Reports. (1)
How many people are using ORCID?