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ResearcherID: H-2842-2017
Scopus Author ID: 55625337400

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Employment (2)

Charles University, First Faculty of Medicine: Praha, CZ

(Institute of Biochemistry and Experimental Oncology)
Employment
Source: Self-asserted source
Jan Hojný

Charles University and General University Hospital in Prague : Prague, CZ

(Institute of Pathology)
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Jan Hojný

Works (50 of 60)

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Page 1 of 2

Altered TP53, CDKN2A, ATM, EPHA7, POT1, CHEK1, GRIN2A, and EGFR Predict Shorter Survival in Penile Squamous Cell Carcinoma

Modern Pathology
2025 | Journal article
DOI: 10.1016/J.MODPAT.2024.100689
WOSUID: WOS:001399563900001
Contributors: Hojny, Jan; Hrudka, Jan; Prouzova, Zuzana; Bartu, Michaela Kendall; Krkavcova, Eva; Dvorak, Jiri; Michalkova, Romana; Capka, David; Zavillova, Nicolette; Matej, Radoslav et al.
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Correlation between p53 immunoexpression and <i>TP53</i> mutation status in extrapulmonary small cell neuroendocrine carcinomas and its association with patient survival

Virchows Archiv
2025 | Journal article
DOI: 10.1007/S00428-025-04024-6
WOSUID: WOS:001403739900001
Contributors: Pavlickova, Klara; Hojny, Jan; Waldauf, Petr; Dundr, Pavel; Hajkova, Nikola; Svajdler, Marian; Fabian, Pavel; Zambo, Iva Staniczkova; Flidrova, Miroslava; Laco, Jan et al.
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Molecular and Immunohistochemical Classification of Extrapulmonary Small Cell Neuroendocrine Carcinomas: A Study of 181 Cases

Laboratory Investigation
2025 | Journal article
DOI: 10.1016/J.LABINV.2025.104093
WOSUID: WOS:001428089700001
Contributors: Pavlickova, Klara; Hojny, Jan; Waldauf, Petr; Svajdler, Marian; Dundr, Pavel; Fabian, Pavel; Krkavcova, Eva; Dvorak, Jirii; Michalkova, Romana; Zambo, Iva Staniczkova et al.
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The Molecular Landscape of 227 Adult Granulosa Cell Tumors of the Ovary: Insights into the Progression from Primary to Recurrence

Laboratory Investigation
2025 | Journal article
DOI: 10.1016/J.LABINV.2024.102201
WOSUID: WOS:001397613400001
Contributors: Michalkova, Romana; Safanda, Adam; Hajkova, Nikola; Hojny, Jan; Krkavcova, Eva; Bartu, Michaela Kendall; Svajdler, Marian; Shatokhina, Tetiana; Laco, Jan; Matej, Radoslav et al.
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The Rare Gynecologic Sarcoma Study: Molecular and Clinicopathologic Results of A Project on 379 Uterine Sarcomas

Laboratory Investigation
2025 | Journal article
DOI: 10.1016/J.LABINV.2025.104092
WOSUID: WOS:001437533100001
Contributors: Dundr, Pavel; Hojny, Jan; Dvorak, Jiri; Hajkova, Nikola; Vrankova, Romana; Krkavcova, Eva; Berjon, Alberto; Bizon, Magdalena; Bobinski, Marcin; Bouda, Jiri et al.
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A comprehensive study evaluating germline <i>FANCG</i> variants in predisposition to breast and ovarian cancer

Cancer Medicine
2024 | Journal article
DOI: 10.1002/CAM4.70103
WOSUID: WOS:001292110200001
Contributors: Soukupova, Jana; Stastna, Barbora; Kanwal, Madiha; Hojny, Jan; Zemankova, Petra; Borecka, Marianna; Cerna, Leona; Cerna, Marta; Cerna, Monika; Curtisova, Vaclava et al.
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Endometrial stromal tumor with whorling and <i>GREB1</i>::<i>CTNNB1</i> fusion-a case report on a rare entity

Virchows Archiv
2024 | Journal article
DOI: 10.1007/S00428-024-03869-7
WOSUID: WOS:001271573900002
Contributors: Bartu, Michaela Kendall; Flidrova, Miroslava; Nemejcova, Kristyna; Hojny, Jan; Dvorak, Jiri; Michalova, Kvetoslava; Dundr, Pavel
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High tumour mutational burden is associated with strong PD-L1 expression, HPV negativity, and worse survival in penile squamous cell carcinoma: an analysis of 165 cases

Pathology
2024 | Journal article
DOI: 10.1016/J.PATHOL.2023.10.010
WOSUID: WOS:001236901100001
Contributors: Hrudka, Jan; Hojny, Jan; Prouzova, Zuzana; Bartu, Michaela kendall; Capka, David; Zavillova, Nicolette; Matej, Radoslav; Waldauf, Petr
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Parallel DNA/RNA NGS Using an Identical Target Enrichment Panel in the Analysis of Hereditary Cancer Predisposition

Folia Biologica
2024 | Journal article
DOI: 10.14712/FB2024070010062
WOSUID: WOS:001243028900004
Contributors: Kleiblova, Petra; Cerna, Marta; Zemankova, Petra; Matejkova, Katerina; Nehasil, Petr; Hojny, Jan; Horackova, Klara; Janatova, Marketa; Soukupova, Jana; Stastna, Barbora et al.
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Somatic Genomic and Transcriptomic Characterization of Primary Ovarian Serous Borderline Tumors and Low-Grade Serous Carcinomas

Journal of Molecular Diagnostics
2024 | Journal article
DOI: 10.1016/J.JMOLDX.2023.12.004
WOSUID: WOS:001220816800001
Contributors: Struzinska, Ivana; Hajkova, Nikola; Hojny, Jan; Krkavcova, Eva; Michalkova, Romana; Bui, Quang Hiep; Matej, Radoslav; Laco, Jan; Drozenova, Jana; Fabian, Pavel et al.
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Unraveling the Molecular Landscape of Uterine Tumor Resembling Ovarian Sex Cord Tumor: Insights From A Clinicopathological, Morphologic, Immunohistochemical, and Molecular Analysis of 35 Cases

Modern Pathology
2024 | Journal article
DOI: 10.1016/J.MODPAT.2024.100611
WOSUID: WOS:001332660100001
Contributors: Flidrova, Miroslava; Hajkova, Nikola; Hojny, Jan; Dvorak, Jiri; Michalkova, Romana; Krkavcova, Eva; Laco, Jan; McCluggage, W. Glenn; Giordano, Giovanna; Silini, Enrico Maria et al.
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Uterine sarcoma with KAT6B/A::KANSL1 fusion: a molecular and clinicopathological study on 9 cases

Virchows Archiv
2024 | Journal article
DOI: 10.1007/S00428-024-03994-3
WOSUID: WOS:001369419200001
Contributors: Dundr, Pavel; Dvorak, Jiri; Krausova, Michaela; Hojny, Jan; Hajkova, Nikola; Struzinska, Ivana; Nemejcova, Kristyna; Ondic, Ondrej; Michal, Michael; Michalova, Kvetoslava et al.
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A comprehensive molecular analysis of 113 primary ovarian clear cell carcinomas reveals common therapeutically significant aberrations

Diagnostic Pathology
2023 | Journal article
DOI: 10.1186/S13000-023-01358-0
WOSUID: WOS:001002555100001
Contributors: Struzinska, Ivana; Hajkova, Nikola; Hojny, Jan; Krkavcova, Eva; Michalkova, Romana; Dvorak, Jiri; Nemejcova, Kristyna; Matej, Radoslav; Laco, Jan; Drozenova, Jana et al.
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HER2 status as a potential predictive biomarker for ovarian clear cell carcinoma

Virchows Archiv
2023 | Journal article
DOI: 10.1007/S00428-023-03640-4
WOSUID: WOS:001060259500001
Contributors: Bartu, Michaela Kendall; Nemejcova, Kristyna; Michalkova, Romana; Struzinska, Ivana; Hajkova, Nikola; Hojny, Jan; Krkavcova, Eva; Laco, Jan; Matej, Radoslav; Drozenova, Jana et al.
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Immune cell infiltration, tumour budding, and the p53 expression pattern are important predictors in penile squamous cell carcinoma: a retrospective study of 152 cases

Pathology
2023 | Journal article
DOI: 10.1016/J.PATHOL.2023.03.010
WOSUID: WOS:001041819200001
Contributors: Hrudka, Jan; Prouzova, Zuzana; Bartu, Michaela Kendall; Hojny, Jan; Capka, David; Zavillova, Nicolette; Matej, Radoslav; Waldauf, Petr
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Microsatellite instability in non-endometrioid ovarian epithelial tumors: a study of 400 cases comparing immunohistochemistry, PCR, and NGS based testing with mutation status of MMR genes

Translational Research
2023 | Journal article
DOI: 10.1016/J.TRSL.2023.05.004
WOSUID: WOS:001067763800001
Contributors: Hajková, Nikola; Bartu, Michaela Kendall; Cibula, David; Drozenova, Jana; Fabian, Pavel; Fadare, Oluwole; Fruehauf, Filip; Hausnerova, Jitka; Hojny, Jan; Krkavcova, Eva et al.
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Primary Mucinous Tumors of the Ovary: An Interobserver Reproducibility and Detailed Molecular Study Reveals Significant Overlap Between Diagnostic Categories

Modern Pathology
2023 | Journal article
DOI: 10.1016/J.MODPAT.2022.100040
WOSUID: WOS:000982550100001
Contributors: Dundr, Pavel; Bartu, Michaela; Bosse, Tjalling; Bui, Quang Hiep; Cibula, David; Drozenova, Jana; Fabian, Pavel; Fadare, Oluwole; Hausnerova, Jitka; Hojny, Jan et al.
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Refined criteria for p53 expression in ovarian mucinous tumours are highly concordant with TP53 mutation status, but p53 expression/TP53 status lack prognostic significance

Pathology
2023 | Journal article
DOI: 10.1016/J.PATHOL.2023.04.008
WOSUID: WOS:001082559400001
Contributors: Dundr, Pavel; Hajkova, Nikola; Bartu, Michaela Kendall; Cibula, David; Drozenova, Jana; Fabian, Pavel; Fadare, Oluwole; Fruhauf, Filip; Hausnerova, Jitka; Hojny, Jan et al.
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Sequencing-based analysis of clonal evolution of 25 mantle cell lymphoma patients at diagnosis and after failure of standard immunochemotherapy

American Journal of Hematology
2023 | Journal article
DOI: 10.1002/AJH.27044
WOSUID: WOS:001052377200001
Contributors: Karolova, J.; Kazantsev, D.; Svaton, M.; Tuskova, L.; Forsterova, K.; Malarikova, D.; Benesova, K.; Heizer, T.; Dolnikova, A.; Klanova, M. et al.
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Soft tissue sarcoma with ZC3H7B::BCOR fusion in a male mimicking low-grade fibromyxoid sarcoma - A case report

Pathology Research and Practice
2023 | Journal article
DOI: 10.1016/J.PRP.2023.154831
WOSUID: WOS:001098794100001
Contributors: Soukup, Jiri; Valtr, Ondrej; Brtkova, Jindra; Zoul, Zdenek; Staniczkova-Zambo, Iva; Hojny, Jan; Kamaradova, Katerina
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Uterine leiomyoma with RAD51B::NUDT3 fusion: a report of 2 cases

Virchows Archiv
2023 | Journal article
DOI: 10.1007/S00428-023-03603-9
WOSUID: WOS:001032022500001
Contributors: Dundr, Pavel; Machado-Lopez, Alba; Mas, Aymara; Veckova, Zuzana; Mara, Michal; Richtarova, Adela; Matej, Radoslav; Struzinska, Ivana; Bartu, Michaela Kendall; Nemejcova, Kristyna et al.
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Chondrosarcoma with Target-Like Chondrocytes: Update on Molecular Profiling and Specific Morphological Features

Folia Biologica
2022 | Journal article
WOSUID: WOS:000908057400004
Contributors: Povysil, C.; Hojny, J.; Kana, M.
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Comprehensive DNA analysis of primary penile carcinoma by target NGS

Annals of Oncology
2022 | Journal article
DOI: 10.1016/J.ANNONC.2022.09.120
WOSUID: WOS:000897938200119
Contributors: Hojny, J.; Michalkova, R.; Krkavcova, E.; Dvorak, J.; Bartu, M.; Hrudka, J.
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Comprehensive quantitative analysis of alternative splicing variants reveals the <i>HNF1B</i> mRNA splicing pattern in various tumour and non-tumour tissues

Scientific Reports
2022 | Journal article
DOI: 10.1038/S41598-021-03989-Z
WOSUID: WOS:000740510500140
Contributors: Hojny, Jan; Michalkova, Romana; Krkavcova, Eva; Bui, Quang Hiep; Bartu, Michaela; Nemejcova, Kristyna; Kalousova, Marta; Kleiblova, Petra; Dundr, Pavel; Struzinska, Ivana
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Desmoplastic Small Round Cell Tumor of the Uterus: A Report of Molecularly Confirmed Case with EWSR1-WT1 Fusion

Diagnostics
2022 | Journal article
DOI: 10.3390/DIAGNOSTICS12051184
WOSUID: WOS:000802635000001
Contributors: Dundr, Pavel; Drozenova, Jana; Matej, Radoslav; Bartu, Michaela; Nemejcova, Kristyna; Robova, Helena; Rob, Lukas; Hojny, Jan; Struzinska, Ivana
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Epithelioid sarcoma with retained INII expression as a cause of a chronic leg ulcer

SAGE Open Medical Case Reports
2022 | Journal article
DOI: 10.1177/2050313X221106259
WOSUID: WOS:000815870100001
Contributors: Manakova, Tatjana; Hojny, Jan; Sedlar, Martin; Vocka, Michal; Chrz, Kristian; Mitas, Petr; Benes, Jiri; Holaj, Robert
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The spectrum of gene fusions in primary epithelial ovarian tumours identified by panel RNA NGS approach

Virchows Archiv
2022 | Journal article
WOSUID: WOS:000842770700460
Contributors: Struzinska, I.; Flidrova, M.; Galko, J.; Jaksa, R.; Nemejcova, K.; Bartu, M.; Bui, Q. H.; Hojny, J.; Dundr, P.
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Uterine cellular leiomyomas are characterized by common HMGA2 aberrations, followed by chromosome 1p deletion and MED12 mutation: morphological, molecular, and immunohistochemical study of 52 cases

Virchows Archiv
2022 | Journal article
DOI: 10.1007/S00428-021-03217-Z
WOSUID: WOS:000705694900001
Contributors: Dundr, Pavel; Gregova, Maria; Hojny, Jan; Krkavcova, Eva; Michalkova, Romana; Nemejcova, Kristyna; Bartu, Michaela; Hajkova, Nikola; Laco, Jan; Mara, Michal et al.
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Whole transcriptome RNA-Seq analysis of formalin-fixed and paraffin-embedded tumour tissue

Annals of Oncology
2022 | Journal article
DOI: 10.1016/J.ANNONC.2022.09.135
WOSUID: WOS:000897938200134
Contributors: Hajkova, N.; Krkavcova, E.; Michalkova, R.; Dvorak, J.; Hojny, J.; Bartu, M.; Struzinska, I.; Nemejcova, K.; Dundr, P.
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A comprehensive analysis of the expression, epigenetic and genetic changes of HNF1B and ECI2 in 122 cases of high-grade serous ovarian carcinoma

Oncology Letters
2021 | Journal article
DOI: 10.3892/OL.2021.12446
WOSUID: WOS:000612858900001
Contributors: Nemejcova, Kristyna; Bartu, Michaela; Hojny, Jan; Hajkova, Nikola; Michalkova, Romana; Krkavcova, Eva; Struzinska, Ivana; Bui, Hiep Quang; Dundr, Pavel; Cibula, David et al.
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Analysis of expression, epigenetic, and genetic changes of HNF1B in 130 kidney tumours

Scientific Reports
2020 | Journal article
DOI: 10.1038/S41598-020-74059-Z
WOSUID: WOS:000582694000018
Contributors: Bartu, Michaela; Hojny, Jan; Hajkova, Nikola; Michalkova, Romana; Krkavcova, Eva; Hadravsky, Ladislav; Kleissnerova, Lenka; Bui, Quang Hiep; Struzinska, Ivana; Nemejcova, Kristyna et al.
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Comprehensive Analysis of PTEN in Primary Cutaneous Melanoma

Folia Biologica
2020 | Journal article
DOI: 10.14712/FB2020066010007
WOSUID: WOS:000549368900002
Contributors: Nemejcova, K.; Dundr, P.; Jaksa, R.; Bartu, M.; Struzinska, I; Hojny, J.; Hajkova, N.; Kodet, O.
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Expression, Epigenetic, and Genetic Changes of HNF1B in Colorectal Lesions: an Analysis of 145 Cases

Pathology & Oncology Research
2020 | Journal article
DOI: 10.1007/S12253-020-00830-2
WOSUID: WOS:000537393700001
Contributors: Bartu, Michaela; Hojny, Jan; Hajkova, Nikola; Michalkova, Romana; Krkavcova, Eva; Simon, Karol; Fryba, Vladimir; Struzinska, Ivana; Nemejcova, Kristyna; Dundr, Pavel
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HNF1B, EZH2 and ECI2 in prostate carcinoma. Molecular, immunohistochemical and clinico-pathological study

Scientific Reports
2020 | Journal article
DOI: 10.1038/S41598-020-71427-7
WOSUID: WOS:000571222300022
Contributors: Dundr, Pavel; Bartu, Michaela; Hojny, Jan; Michalkova, Romana; Hajkova, Nikola; Struzinska, Ivana; Krkavcova, Eva; Hadravsky, Ladislav; Kleissnerova, Lenka; Kopejskova, Jana et al.
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Identification of novel HNF1B mRNA splicing variants and their qualitative and semi-quantitative profile in selected healthy and tumour tissues

Scientific Reports
2020 | Journal article
DOI: 10.1038/S41598-020-63733-X
WOSUID: WOS:000559768000001
Contributors: Hojny, Jan; Bartu, Michaela; Krkavcova, Eva; Nemejcova, Kristyna; Sevcik, Jan; Cibula, David; Fryba, Vladimir; Plincelnerova, Lenka; Dundr, Pavel; Struzinska, Ivana
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Leiomyoma with Bizarre Nuclei: a Study of 108 Cases Focusing on Clinicopathological Features, Morphology, and Fumarate Hydratase Alterations

Pathology & Oncology Research
2020 | Journal article
DOI: 10.1007/S12253-019-00739-5
WOSUID: WOS:000540615800020
Contributors: Gregova, Maria; Hojny, Jan; Nemejcova, Kristyna; Bartu, Michaela; Mara, Michal; Boudova, Barbora; Laco, Jan; Krbal, Lukas; Ticha, Ivana; Dundr, Pavel
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MICROSCOPIC EXTRAOVARIAN SEX CORD PROLIFERATION: REPORT OF A CASE WITH BILATERAL FALLOPIAN TUBE INVOLVEMENT AND A COMPREHENSIVE MOLECULAR ANALYSIS

Polish Journal of Pathology
2020 | Journal article
DOI: 10.5114/PJP.2020.97023
WOSUID: WOS:000552141700011
Contributors: Dundr, Pavel; Veckova, Zuzana; Ticha, Ivana; Hojny, Jan; Nemejcova, Kristyna; Bartu, Michaela
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Ovarian mesonephric-like adenocarcinoma arising in serous borderline tumor: a case report with complex morphological and molecular analysis

Diagnostic Pathology
2020 | Journal article
DOI: 10.1186/S13000-020-01012-Z
WOSUID: WOS:000554461200003
Contributors: Dundr, Pavel; Gregova, Maria; Nemejcova, Kristyna; Bartu, Michaela; Hajkova, Nikola; Hojny, Jan; Struzinska, Ivana; Fischerova, Daniela
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Results of targeted next-generation sequencing in children with cystic kidney diseases often change the clinical diagnosis

Plos One
2020 | Journal article
DOI: 10.1371/JOURNAL.PONE.0235071
WOSUID: WOS:000544972400048
Contributors: Obeidova, Lena; Seeman, Tomas; Fencl, Filip; Blahova, Kveta; Hojny, Jan; Elisakova, Veronika; Reiterova, Jana; Stekrova, Jitka
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A comprehensive evaluation of pathogenic mutations in primary cutaneous melanomas, including the identification of novel loss-of-function variants

Scientific Reports
2019 | Journal article
DOI: 10.1038/S41598-019-53636-X
WOSUID: WOS:000497701800007
Contributors: Ticha, Ivana; Hojny, Jan; Michalkova, Romana; Kodet, Ondrej; Krkavcova, Eva; Hajkova, Nikola; Nemejcova, Kristyna; Bartu, Michaela; Jaksa, Radek; Dura, Miroslav et al.
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Comprehensive evaluation of the mutational spectra detected in primary cutaneous melanomas: identification of novel loss-of-function mutants of TP53

Virchows Archiv
2019 | Journal article
WOSUID: WOS:000483546902003
Contributors: Ticha, I.; Jaksa, R.; Hojny, J.; Bartu, M.; Nemejcova, K.; Hajkova, N.; Michalkova, R.; Krkavcova, E.; Kodet, O.; Macurek, L. et al.
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Detection of novel HNF1B mRNA splicing variants in selected tissues

Virchows Archiv
2019 | Journal article
WOSUID: WOS:000483546901152
Contributors: Bartu, M.; Rosmusova, J.; Kopejskova, J.; Hadravsky, L.; Hojny, J.; Nemejcova, K.; Ticha, I.; Dundr, P.
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Identification of deleterious germline <i>CHEK2</i> mutations and their association with breast and ovarian cancer

International Journal of Cancer
2019 | Journal article
DOI: 10.1002/IJC.32385
WOSUID: WOS:000479320800008
Contributors: Kleiblova, Petra; Stolarova, Lenka; Krizova, Katerina; Lhota, Filip; Hojny, Jan; Zemankova, Petra; Havranek, Ondrej; Vocka, Michal; Cerna, Marta; Lhotova, Klara et al.
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Synchronous endometrioid endometrial and ovarian carcinomas are biologically related: A clinico-pathological and molecular (next generation sequencing) study of 22 cases

Oncology Letters
2019 | Journal article
DOI: 10.3892/OL.2018.9855
WOSUID: WOS:000459551800099
Contributors: Hajkova, Nikola; Ticha, Ivana; Hojny, Jan; Nemejcova, Kristyna; Bartu, Michaela; Michalkova, Romana; Zikan, Michal; Cibula, David; Laco, Jan; Geryk, Tomas et al.
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Complex DNA analysis of polycystic kidney disease

European Journal of Human Genetics
2018 | Journal article
WOSUID: WOS:000489312601191
Contributors: Obeidova, L.; Hojny, J.; Elisakova, V.; Kavec, M.; Seeman, T.; Reiterova, J.; Stekrova, J.
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Germline mutation in the TP53 gene in uveal melanoma

Scientific Reports
2018 | Journal article
DOI: 10.1038/S41598-018-26040-0
WOSUID: WOS:000432270500003
Contributors: Hajkova, Nikola; Hojny, Jan; Nemejcova, Kristyna; Dundr, Pavel; Ulrych, Jan; Jirsova, Katerina; Glezgova, Johana; Ticha, Ivana
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Identification of HNF1B mRNA splicing variants in different tissues - preliminary results

Virchows Archiv
2018 | Journal article
WOSUID: WOS:000443414104007
Contributors: Hojny, J.; Bartu, M.; Rosmusova, J.; Ticha, I.; Hajkova, N.; Nemejcova, K.; Dundr, P.
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Leiomyoma with bizarre nuclei. A study of 108 cases focusing on clinicopathological features, morphology and fumarate hydratase alterations

Virchows Archiv
2018 | Journal article
DOI: 10.26226/MORRESSIER.5B4709876F4CB30010951BA0
WOSUID: WOS:000443414101283
Contributors: Gregova, M.; Nemejcova, K.; Bartu, M.; Mara, M.; Boudova, B.; Ticha, I.; Hojny, J.; Laco, J.; Krbal, L.; Dundr, P.
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Spectrum and frequency of mutations detected by NGS panel in primary melanomas

Virchows Archiv
2018 | Journal article
DOI: 10.26226/MORRESSIER.5B4709886F4CB300109519AE
WOSUID: WOS:000443414102078
Contributors: Ticha, I.; Hojny, J.; Nemejcova, K.; Bartu, M.; Kodet, O.; Hajkova, N.; Michalkova, R.; Krkavcova, E.; Dundr, P.
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The Role of HNF1B in Tumorigenesis of Solid Tumours: a Review of Current Knowledge

Folia Biologica
2018 | Journal article
DOI: 10.14712/FB2018064030071
WOSUID: WOS:000451065000001
Contributors: Bartu, M.; Dundr, P.; Nemejcova, K.; Ticha, I.; Hojny, H.; Hajkova, N.
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