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ResearcherID: A-3392-2014
Scopus Author ID: 55942783400
Loop profile: 584563

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Works (30)

Open-Source Approach to GPU-Accelerated Substructure Search

Journal of Chemical Information and Modeling
2024-09-23 | Journal article
DOI: 10.1021/acs.jcim.4c00679
Part of ISSN: 1549-9596
Part of ISSN: 1549-960X
Contributors: Andrew J. Whitehouse; Melchor Sanchez-Martinez; Seyedeh Maryam Salehi; Natalja Kurbatova; Euan Dean
Source: Self-asserted source
Melchor Sanchez-Martinez

Trends in Medicinal Chemistry: KNIME Workflows, QSAR Models, LLMs and Chemical Search Strategies

CHIMIA
2023-11-29 | Journal article
DOI: 10.2533/chimia.2023.786
Part of ISSN: 2673-2424
Part of ISSN: 0009-4293
Contributors: Seyedeh Maryam Salehi; Melchor Sanchez-Martinez; Kristina Goncharenko; Natalja Kurbatova
Source: Self-asserted source
Melchor Sanchez-Martinez

2-(Fluoromethoxy)-4′-(S-methanesulfonimidoyl)-1,1′-biphenyl (UCM-1306), an Orally Bioavailable Positive Allosteric Modulator of the Human Dopamine D1 Receptor for Parkinson’s Disease

Journal of Medicinal Chemistry
2022-09-22 | Journal article
DOI: 10.1021/acs.jmedchem.2c00949
Contributors: Javier García-Cárceles; Henar Vázquez-Villa; José Brea; David Ladron de Guevara-Miranda; Giovanni Cincilla; Melchor Sánchez-Martínez; Anabel Sánchez-Merino; Sergio Algar; María Teresa de los Frailes; Richard S. Roberts et al.
Source: check_circle
Crossref

Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA2), UCM-14216, Ameliorates Spinal Cord Injury in Mice

Journal of Medicinal Chemistry
2022-08-25 | Journal article
DOI: 10.1021/acs.jmedchem.2c00046
Contributors: Nora Khiar-Fernández; Debora Zian; Henar Vázquez-Villa; R. Fernando Martínez; Andrea Escobar-Peña; Román Foronda-Sainz; Manisha Ray; Maria Puigdomenech-Poch; Giovanni Cincilla; Melchor Sánchez-Martínez et al.
Source: check_circle
Crossref

The role of antibody responses against glycans in bioprosthetic heart valve calcification and deterioration

Nature Medicine
2022-02-17 | Journal article
DOI: 10.1038/s41591-022-01682-w
Part of ISSN: 1078-8956
Part of ISSN: 1546-170X
Source: Self-asserted source
Melchor Sanchez-Martinez

Computer-Aided Drug Design (CADD) to De-Orphanize Marine Molecules: Finding Potential Therapeutic Agents for Neurodegenerative and Cardiovascular Diseases

Marine Drugs
2022-01-05 | Journal article
DOI: 10.3390/md20010053
Contributors: Laura Llorach-Pares; Alfons Nonell-Canals; Conxita Avila; Melchor Sanchez-Martinez
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Crossref
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As A Computational Chemist in the Pharma Sector

ChemViews
2020 | Journal article
DOI: 10.1002/chemv.202000077
Contributors: Gian Asara; Melchor Sanchez-Martinez
Source: check_circle
Crossref

Mimetics of extra virgin olive oil phenols with anti-cancer stem cell activity

Aging
2020-11-15 | Journal article
DOI: 10.18632/aging.202154
Source: Self-asserted source
Melchor Sanchez-Martinez

Meridianins and Lignarenone B as Potential GSK3β Inhibitors and Inductors of Structural Neuronal Plasticity

Biomolecules
2020-04-21 | Journal article
DOI: 10.3390/biom10040639
Contributors: Laura Llorach-Pares; Ened Rodriguez-Urgelles; Alfons Nonell-Canals; Jordi Alberch; Conxita Avila; Melchor Sanchez-Martinez; Albert Giralt
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Crossref
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A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration

Journal of Medicinal Chemistry
2019-12-16 | Journal article
DOI: 10.1021/acs.jmedchem.9b01287
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Source: Self-asserted source
Melchor Sanchez-Martinez

Computational de-orphanization of the olive oil biophenol oleacein: Discovery of new metabolic and epigenetic targets

Food and Chemical Toxicology
2019-09 | Journal article
DOI: 10.1016/j.fct.2019.05.037
Part of ISSN: 0278-6915
Source: Self-asserted source
Melchor Sanchez-Martinez

Extra Virgin Olive Oil Contains a Phenolic Inhibitor of the Histone Demethylase LSD1/KDM1A

Nutrients
2019-07-19 | Journal article
DOI: 10.3390/nu11071656
Contributors: Elisabet Cuyàs; Juan Gumuzio; Jesús Lozano-Sánchez; David Carreras; Sara Verdura; Laura Llorach-Parés; Melchor Sanchez-Martinez; Elisabet Selga; Guillermo J. Pérez; Fabiana S. Scornik et al.
Source: check_circle
Crossref

The extra virgin olive oil phenolic oleacein is a dual substrate-inhibitor of catechol-O-methyltransferase

Food and Chemical Toxicology
2019-06 | Journal article
DOI: 10.1016/j.fct.2019.03.049
Part of ISSN: 0278-6915
Source: Self-asserted source
Melchor Sanchez-Martinez

Silibinin is a direct inhibitor of {STAT3}

Food and Chemical Toxicology
2018 | Journal article
DOI: https://doi.org/10.1016/j.fct.2018.04.028
Source: Self-asserted source
Melchor Sanchez-Martinez

STAT3 labels a subpopulation of reactive astrocytes required for brain metastasis

Nature Medicine
2018 | Journal article
DOI: 10.1038/s41591-018-0044-4
Source: Self-asserted source
Melchor Sanchez-Martinez

An olive oil phenolic is a new chemotype of mutant isocitrate dehydrogenase 1 (IDH1) inhibitors

Carcinogenesis
2018-11-14 | Journal article
DOI: 10.1093/carcin/bgy159
Source: Self-asserted source
Melchor Sanchez-Martinez

Metformin Is a Direct SIRT1-Activating Compound: Computational Modeling and Experimental Validation

Frontiers in Endocrinology
2018-11-06 | Journal article
DOI: 10.3389/fendo.2018.00657
Source: Self-asserted source
Melchor Sanchez-Martinez

Kororamides, Convolutamines, and Indole Derivatives as Possible Tau and Dual-Specificity Kinase Inhibitors for Alzheimer’s Disease: A Computational Study

Marine Drugs
2018-10-16 | Journal article
DOI: 10.3390/md16100386
Contributors: Laura Llorach-Pares; Alfons Nonell-Canals; Conxita Avila; Melchor Sanchez-Martinez
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Metformin directly targets the H3K27me3 demethylase KDM6A/UTX.

Aging cell
2018-05 | Journal article
DOI: 10.1111/acel.12772
PMID: 29740925
Contributors: Cuyàs E; Verdura S; Llorach-Pares L; Fernández-Arroyo S; Luciano-Mateo F; Cabré N; Stursa J; Werner L; Martin-Castillo B; Viollet B et al.
Source: Self-asserted source
Melchor Sanchez-Martinez via Europe PubMed Central

Extra-virgin olive oil contains a metabolo-epigenetic inhibitor of cancer stem cells

Carcinogenesis
2018-02-14 | Journal article
DOI: 10.1093/carcin/bgy023
ARXIV:

/oup/backfile/content_public/journal/carcin/pap/10.1093_carcin_bgy023/1/bgy023.pdf
Source: Self-asserted source
Melchor Sanchez-Martinez

Amyloid-induced β-cell dysfunction and islet inflammation are ameliorated by 4-phenylbutyrate (PBA) treatment

The FASEB Journal
2017 | Journal article
DOI: 10.1096/fj.201700236R
ARXIV:

http://www.fasebj.org/content/early/2017/08/14/fj.201700236R.full.pdf+html
Source: Self-asserted source
Melchor Sanchez-Martinez

Computer-Aided Drug Design Applied to Marine Drug Discovery: Meridianins as Alzheimer’s Disease Therapeutic Agents

Marine Drugs
2017-11 | Journal article
DOI: 10.3390/md15120366
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Machine-Learning QSAR Model for Predicting Activity against Malaria Parasite’s Ion Pump PfATP4 and In Silico Binding Assay Validation

Proceedings
2017-10-18 | Journal article
DOI: 10.3390/proceedings1060652
Source: Self-asserted source
Melchor Sanchez-Martinez

Intrinsically Disordered Proteins as Drug Targets

MOJ Proteomics and Bioinformatics
2017-03-10 | Journal article
DOI: 10.15406/mojpb.2017.05.00157
Source: Self-asserted source
Melchor Sanchez-Martinez

Treatment with chemical chaperone 4-phenylbutyrate restores glucose metabolism in mice overexpressing human islet amyloid polypeptide

DIABETOLOGIA
2016 | Conference paper
Source: Self-asserted source
Melchor Sanchez-Martinez

Interplay between Enzyme Function and Protein Dynamics: A Multiscale Approach to the Study of the NAG Kinase Family and Two Class II Aldolases

Computational Approaches to Protein Dynamics
2015 | Book chapter
Source: Self-asserted source
Melchor Sanchez-Martinez

Application of the Maximum Entropy Principle to determine ensembles of Intrinsically Disordered Proteins from Residual Dipolar Couplings

Physical Chemistry Chemical Physics
2014 | Journal article
DOI:

10.1039/C4CP03114H
Contributors: Sanchez-Martinez, Melchor; Crehuet, Ramon
Source: Self-asserted source
Melchor Sanchez-Martinez via ResearcherID

Enzymatic Minimum Free Energy Path Calculations Using Swarms of Trajectories

The Journal of Physical Chemistry B
2014 | Journal article
DOI:

10.1021/jp506593t
Contributors: Sanchez-Martinez, Melchor; Field, Martin J.; Crehuet, Ramon
Source: Self-asserted source
Melchor Sanchez-Martinez via ResearcherID

Conformational Compression and Barrier Height Heterogeneity in the N-Acetylglutamate Kinase

Journal of Physical Chemistry B
2013 | Journal article
Contributors: Sanchez-Martinez, Melchor; Marcos, Enrique; Tauler, Roma; Field, Martin; Crehuet, Ramon
Source: Self-asserted source
Melchor Sanchez-Martinez via ResearcherID

SS-map: Visualizing cooperative secondary structure elements in protein ensembles

Intrinsically Disordered Proteins
2013 | Journal article
Contributors: Iglesias, Jelisa; Sanchez-Martínez, Melchor; Crehuet, Ramon
Source: Self-asserted source
Melchor Sanchez-Martinez via ResearcherID
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