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Keywords

Cryo-EM, structural biology, virology, picornaviruses, parechoviruses, monoclonal antibodies, antivi

Countries

Finland

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Employment (4)

University of Helsinki: Helsinki, FI

Employment
Source: check_circle
University of Helsinki

University of Helsinki: Helsinki, FI

2016-08-01 to present | Senior Postdoctoral Scientist
Employment
Source: Self-asserted source
Ausra Domanska

University of Helsinki: Helsinki, FI

2014-08-01 to 2016-07-31 | Marie Curie Postdoctoral Fellow
Employment
Source: Self-asserted source
Ausra Domanska

German Cancer Research Center: Heidelberg, DE

2008-01-01 to 2010-09-01 | Postdoctoral fellow
Employment
Source: Self-asserted source
Ausra Domanska

Education and qualifications (2)

University of Helsinki: Helsinki, FI

2017-03-10 to present | Docent/Adjunct Professor
Education
Source: Self-asserted source
Ausra Domanska

Vilnius University: Vilnius, LT

2001-01-01 to 2005-06-31 | PhD
Education
Source: Self-asserted source
Ausra Domanska

Funding (5)

HPeV3 structural and functional studies

2014-08 to 2016-07 | Grant
Seventh Framework Programme of the EU, REA (Brussels, BE)
GRANT_NUMBER:

PIEF-GA-2013-628150
Source: Self-asserted source
Ausra Domanska

Interplay between small non-structural proteins (NS2) of minute virus of mice (MVM) and cellular factors

2008-07 to 2010-07 | Grant
Alexander von Humboldt-Stiftung (Berlin, DE)
Source: Self-asserted source
Ausra Domanska

Studying functions of non-structural proteins of parvovirus minute virus of mice

2008-01 to 2008-06 | Grant
German Cancer Research Center (Heidelberg, DE)
Source: Self-asserted source
Ausra Domanska

Studies on bacteriophage Bam35 entry

2007-08 to 2007-09 | Award
EU structural Funds for Lithuania (2004-2006) (Brussels, BE)
GRANT_NUMBER:

BPD2004-ESF-2.5.0-03-05/0055
Source: Self-asserted source
Ausra Domanska

Studies on membrane-containing bacterial virus entry

2004-01 to 2004-05 | Salary award
CIMO (Centre for International Mobility) fellowship (Helsinki, FI)
Source: Self-asserted source
Ausra Domanska

Works (30)

VitroJet: new features and case studies

Acta crystallographica. Section D, Structural biology
2024 | Journal article | Author
DOI: 10.1107/S2059798324001852
SOURCE-WORK-ID:

c978c11a-5b59-4957-ada4-57b4b5117d92

WOSUID:

001208750500002

EID:

2-s2.0-85190176239
Contributors: Rene JM Henderikx; Daniel Mann; Ausra Domanska; Jing Dong; Saba Shahzad; Behnam Lak; Aikaterini Filopoulou; Damian Ludig; Martin Grininger; Jeffrey Momoh et al.
Source: check_circle
University of Helsinki

SAR Analysis of Novel Coxsackie virus A9 Capsid Binders

Journal of Medicinal Chemistry
2024-09-18 | Journal article | Author
DOI: 10.1021/acs.jmedchem.4c00701
SOURCE-WORK-ID:

af47fa22-6b7d-48e7-88b9-946e3d6e21d7

WOSUID:

001315707100001

PMID: 39292620
EID:

2-s2.0-85205702382
Contributors: Chiara Tammaro; Zlatka Plavec; Laura Myllymäki; Cristopher Mitchell; S Consalvi; M Biava; A Ciogli; Ausra Domanska; Valtteri Leppilampi; Cienna Buckner et al.
Source: check_circle
University of Helsinki

The structure of immature tick-borne encephalitis virus supports the collapse model of flavivirus maturation

Science Advances
2024-07-05 | Journal article
DOI: 10.1126/sciadv.adl1888
Contributors: Maria Anastasina; Tibor Füzik; Aušra Domanska; Lauri Ilmari Aurelius Pulkkinen; Lenka Šmerdová; Petra Pokorná Formanová; Petra Straková; Jiří Nováček; Daniel Růžek; Pavel Plevka et al.
Source: check_circle
Crossref
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The structure of immature tick-borne encephalitis virus

2023-08-04 | Preprint
DOI: 10.1101/2023.08.04.551633
Contributors: Maria Anastasina; Tibor Füzik; Aušra Domanska; Lauri IA Pulkkinen; Lenka Šmerdová; Petra Pokorná Formanová; Petra Straková; Jiří Nováček; Daniel Růžek; Pavel Plevka et al.
Source: check_circle
Crossref

Structural Studies Reveal that Endosomal Cations Promote Formation of Infectious Coxsackievirus A9 A-Particles, Facilitating RNA and VP4 Release

Journal of Virology
2022-12-21 | Journal article
DOI: 10.1128/jvi.01367-22
Contributors: Aušra Domanska; Zlatka Plavec; Visa Ruokolainen; Benita Löflund; Varpu Marjomäki; Sarah J. Butcher; Susana López
Source: check_circle
Crossref
grade
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SARS-CoV-2 Production, Purification Methods and UV Inactivation for Proteomics and Structural Studies

Viruses
2022-09-08 | Journal article
DOI: 10.3390/v14091989
Contributors: Zlatka Plavec; Aušra Domanska; Xiaonan Liu; Pia Laine; Lars Paulin; Markku Varjosalo; Petri Auvinen; Sharon G. Wolf; Maria Anastasina; Sarah J. Butcher
Source: check_circle
Crossref
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Structural studies reveal that endosomal cations promote formation of infectious CVA9 A particles, facilitating RNA and VP4 release

2022-09-06 | Preprint
DOI: 10.1101/2022.09.02.506448
Contributors: Aušra Domanska; Zlatka Plavec; Visa Ruokolainen; Benita Löflund; Varpu Marjomäki; Sarah J Butcher
Source: check_circle
Crossref

Molecular Organisation of Tick-Borne Encephalitis Virus

Viruses
2022-04 | Journal article | Author
DOI: 10.3390/v14040792
Contributors: Lauri Ilmari Aurelius Pulkkinen; Sarah Barrass; Ausra Domanska; Anna Överby Wernstedt; Maria Anastasina; Sarah Jane Butcher
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 3)‎

A comparative analysis of parechovirus protein structures with other picornaviruses

Open Biology
2021-07 | Journal article
DOI: 10.1098/rsob.210008
Contributors: Aušra Domanska; Sergey Guryanov; Sarah J. Butcher
Source: check_circle
Crossref
grade
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Bacterial and Archeal Virus Entry

Encyclopedia of Virology
2021-03 | Book chapter | Author
DOI: 10.1016/B978-0-12-814515-9.00050-3
SOURCE-WORK-ID:

b693b591-5890-4803-8ae5-a6d74bd90f8e

Part of ISBN: 978-0-12-814516-6
Part of ISBN: 978-0-12-814515-9
Contributors: Minna Marjetta Poranen; Ausra Domanska
Source: check_circle
University of Helsinki

Identification of a conserved virion-stabilizing network inside the interprotomer pocket of enteroviruses

Communications Biology
2021-02-26 | Journal article
DOI: 10.1038/s42003-021-01779-x
Contributors: Justin W. Flatt; Aušra Domanska; Alma L. Seppälä; Sarah J. Butcher
Source: check_circle
Crossref
grade
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Identification of a conserved virion-stabilizing network inside the interprotomer pocket of enteroviruses

2020-07-06 | Preprint
DOI: 10.1101/2020.07.06.189373
Contributors: Justin W. Flatt; Aušra Domanska; Alma L. Seppälä; Sarah J. Butcher
Source: check_circle
Crossref

Extracellular Albumin and Endosomal Ions Prime Enterovirus Particles for Uncoating That Can Be Prevented by Fatty Acid Saturation

Journal of Virology
2019-09 | Journal article
DOI: 10.1128/JVI.00599-19
Contributors: Visa Ruokolainen; Aušra Domanska; Mira Laajala; Maria Pelliccia; Sarah J. Butcher; Varpu Marjomäki; Susana López
Source: check_circle
Crossref
grade
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A novel druggable interprotomer pocket in the capsid of rhino- and enteroviruses

PLOS Biology
2019-06-11 | Journal article
DOI: 10.1371/journal.pbio.3000281
Contributors: Rana Abdelnabi; Chaitan Khosla; James A. Geraets; Yipeng Ma; Carmen Mirabelli; Justin W. Flatt; Aušra Domanska; Leen Delang; Dirk Jochmans; Timiri Ajay Kumar et al.
Source: check_circle
Crossref
grade
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A 2.8-Angstrom-Resolution Cryo-Electron Microscopy Structure of Human Parechovirus 3 in Complex with Fab from a Neutralizing Antibody

Journal of Virology
2019-02-15 | Journal article
DOI: 10.1128/JVI.01597-18
Contributors: Aušra Domanska; Justin W. Flatt; Joonas J. J. Jukonen; James A. Geraets; Sarah J. Butcher; Terence S. Dermody
Source: check_circle
Crossref
grade
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2.8 Å resolution cryo-EM structure of human parechovirus 3 in complex with Fab from a neutralizing antibody

2018-09-06 | Other
DOI: 10.1101/410217
Contributors: Aušra Domanska; Justin W. Flatt; Joonas J.J. Jukonen; James A. Geraets; Sarah J. Butcher
Source: check_circle
Crossref

Strain-dependent neutralization reveals antigenic variation of human parechovirus 3.

Scientific reports
2017-09 | Journal article
DOI: 10.1038/s41598-017-12458-5
PMID: 28935894
PMC: PMC5608956
Source: Self-asserted source
Ausra Domanska via Europe PubMed Central
grade
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Human picornaviruses associated with neurological diseases and their neutralization by antibodies.

The Journal of general virology
2017-06 | Journal article
DOI: 10.1099/jgv.0.000780
PMID: 28631594
Source: Self-asserted source
Ausra Domanska via Europe PubMed Central
grade
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Multiple capsid-stabilizing interactions revealed in a high-resolution structure of an emerging picornavirus causing neonatal sepsis.

2016 | Journal article
DOI: 10.1038/ncomms11387
PMID: 27435188
PMC: PMC4961769
Contributors: Shakeel S; Westerhuis BM; Domanska A; Koning RI; Matadeen R; Koster AJ; Bakker AQ; Beaumont T; Wolthers KC; Butcher SJ
Source: Self-asserted source
Ausra Domanska via Europe PubMed Central
grade
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Monolithic ion exchange chromatographic methods for virus purification.

2012-12 | Journal article
DOI: 10.1016/j.virol.2012.09.019
PMID: 23089255
Contributors: Oksanen HM; Domanska A; Bamford DH
Source: Self-asserted source
Ausra Domanska via Europe PubMed Central
grade
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New, closely related haloarchaeal viral elements with different nucleic Acid types.

2010-04 | Journal article
DOI: 10.1128/jvi.01879-09
PMID: 20089654
PMC: PMC2838124
Contributors: Roine E; Kukkaro P; Paulin L; Laurinavicius S; Domanska A; Somerharju P; Bamford DH
Source: Self-asserted source
Ausra Domanska via Europe PubMed Central
grade
Preferred source (of 2)‎

Virus entry to bacterial cells

Encyclopedia of virology
2008 | Book chapter | Author
SOURCE-WORK-ID:

b9a7499c-3b42-49b4-9b1b-0bda13426287

EID:

2-s2.0-84455199960
Contributors: Minna Marjetta Poranen; Ausra Domanska
Source: check_circle
University of Helsinki

Virus entry to bacterial cells

"Encyclopedia of Virology" 3rd Edition Ed. B. Mahy & M. Van Regenmortel
2008 | Book chapter
Source: Self-asserted source
Ausra Domanska

Bacteria, phages and septicemia.

2007 | Journal article
DOI: 10.1371/journal.pone.0001145
PMID: 18188406
PMC: PMC2190619
Contributors: Gaidelyte A; Vaara M; Bamford DH
Source: Self-asserted source
Ausra Domanska via Europe PubMed Central
grade
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On-line monitoring of changes in host cell physiology during the one-step growth cycle of Bacillus phage Bam35.

2007-04 | Journal article
DOI: 10.1016/j.mimet.2006.12.023
PMID: 17289190
Contributors: Daugelavicius R; Gaidelyte A; Cvirkaite-Krupovic V; Bamford DH
Source: Self-asserted source
Ausra Domanska via Europe PubMed Central
grade
Preferred source (of 2)‎

The entry mechanism of membrane-containing phage Bam35 infecting Bacillus thuringiensis.

2006-08 | Journal article
DOI: 10.1128/jb.00107-06
PMID: 16885461
PMC: PMC1540063
Contributors: Gaidelyte A; Cvirkaite-Krupovic V; Daugelavicius R; Bamford JK; Bamford DH
Source: Self-asserted source
Ausra Domanska via Europe PubMed Central
grade
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The linear double-stranded DNA of phage Bam35 enters lysogenic host cells, but the late phage functions are suppressed.

2005-05 | Journal article
DOI: 10.1128/jb.187.10.3521-3527.2005
PMID: 15866940
PMC: PMC1112020
Contributors: Gaidelyte A; Jaatinen ST; Daugelavicius R; Bamford JK; Bamford DH
Source: Self-asserted source
Ausra Domanska via Europe PubMed Central
grade
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Penetration of enveloped double-stranded RNA bacteriophages phi13 and phi6 into Pseudomonas syringae cells.

2005-04 | Journal article
DOI: 10.1128/jvi.79.8.5017-5026.2005
PMID: 15795287
PMC: PMC1069564
Contributors: Daugelavicius R; Cvirkaite V; Gaidelyte A; Bakiene E; Gabrenaite-Verkhovskaya R; Bamford DH
Source: Self-asserted source
Ausra Domanska via Europe PubMed Central
grade
Preferred source (of 2)‎

Comparative analysis of bacterial viruses Bam35, infecting a gram-positive host, and PRD1, infecting gram-negative hosts, demonstrates a viral lineage.

2003-09 | Journal article
DOI: 10.1016/s0042-6822(03)00295-2
PMID: 12954208
Contributors: Ravantti JJ; Gaidelyte A; Bamford DH; Bamford JK
Source: Self-asserted source
Ausra Domanska via Europe PubMed Central

Two distinct mechanisms ensure transcriptional polarity in double-stranded RNA bacteriophages.

2003-01 | Journal article
DOI: 10.1128/jvi.77.2.1195-1203.2003
PMID: 12502836
PMC: PMC140774
Contributors: Yang H; Makeyev EV; Butcher SJ; Gaidelyte A; Bamford DH
Source: Self-asserted source
Ausra Domanska via Europe PubMed Central
grade
Preferred source (of 2)‎

Peer review (3 reviews for 3 publications/grants)

Review activity for Journal of general virology. (1)
Review activity for Nature communications (1)
Review activity for PloS one. (1)
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