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United Kingdom

Activities

Employment (6)

University of Bristol: Bristol, Bristol, GB

2004-09-01 to present | Professor of Biochemistry (following lecturer, senior lecturer and reader) (School of Biochemistry)
Employment
Source: Self-asserted source
Ian Collinson

Max-Planck-Gesellschaft: Frankfurt am Main, DE

2001-03-01 to 2004-09-30 | Group leader (Biophysics, structural biology)
Employment
Source: Self-asserted source
Ian Collinson

Harvard Medical School: Boston, MA, US

1998-09-30 to 2001-09-01 | Postdoc (Cell Biology)
Employment
Source: Self-asserted source
Ian Collinson

Max-Planck-Gesellschaft: Frankfurt am Main, DE

1997-02-01 to 1998-09-30 (Biophysics, structural biology)
Employment
Source: Self-asserted source
Ian Collinson

EMBL Heidelberg: Heidelberg, DE

1996-10-01 to 1997-02-28 | Postdoc (Structural Biology)
Employment
Source: Self-asserted source
Ian Collinson

MRC Laboratory of Molecular Biology: Cambridge, Cambridgeshire, GB

1994-09-30 to 1996-09-30 | Postdoc (PNAC)
Employment
Source: Self-asserted source
Ian Collinson

Education and qualifications (2)

MRC Laboratory of Molecular Biology: Cambridge, Cambridgeshire, GB

1991-10-01 to 1994-09-30 | PhD (PNAC)
Qualification
Source: Self-asserted source
Ian Collinson

University of Warwick: Coventry, West Midlands, GB

1988-10-01 to 1991-06-30 | BSc (Biochemistry)
Qualification
Source: Self-asserted source
Ian Collinson

Professional activities (3)

Leverhulme Trust: London, GB

2010-01-01 to 2010-12-31 | Research Fellowship of The Royal Society
Invited position
Source: Self-asserted source
Ian Collinson

Biochemical Society: London, London, GB

2005-01-01 to 2005-12-31 | Colworth Medal
Distinction
Source: Self-asserted source
Ian Collinson

EMBO: Heidelberg, DE

2002-01-01 to 2005-01-01 | Young Investigator
Invited position
Source: Self-asserted source
Ian Collinson

Funding (18)

The Bacterial Secretosome

2019-03-01 to 2022-02-28 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/S008349/1
Source: Self-asserted source
Ian Collinson via DimensionsWizard

Dynamic Cell Biology

2017-10-01 to 2023-09-30 | Grant
Wellcome Trust (London, GB)
GRANT_NUMBER:

108907/B/15/Z

Source: Self-asserted source
Ian Collinson via DimensionsWizard

BlueCryo Image Processing Computing Cluster

2017-08-14 to 2018-08-13 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/R000484/1
Source: Self-asserted source
Ian Collinson via DimensionsWizard

Membrane protein insertion and quality control by the bacterial holo-translocon and FtsH chaperone/protease complex

2017-01-09 to 2020-01-08 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/P000940/1
Source: Self-asserted source
Ian Collinson via DimensionsWizard

South West Regional Facility for High-Resolution Electron Cryo-Microscopy

2016-11-01 to 2021-11-01 | Grant
Wellcome Trust (London, GB)
GRANT_NUMBER:

202904/Z/16/Z

Source: Self-asserted source
Ian Collinson via DimensionsWizard

Deciphering the allosteric mechanism of protein translocation through membranes

2016-09-30 to 2018-11-20 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/N015126/1
Source: Self-asserted source
Ian Collinson via DimensionsWizard

Understanding mitochondrial protein import and membrane insertion.

2014-11-01 to 2019-10-31 | Grant
Wellcome Trust (London, GB)
GRANT_NUMBER:

104632/Z/14/Z

Source: Self-asserted source
Ian Collinson via DimensionsWizard

Centre for structural analysis of complex biological systems

2014-10-31 to 2015-10-30 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, Wiltshire, GB)
GRANT_NUMBER: BB/M012107/1
Source: Self-asserted source
Ian Collinson via DimensionsWizard

Understanding the Mechanism of Membrane Protein Insertion

2014-09-30 to 2017-09-29 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, Wiltshire, GB)
GRANT_NUMBER: BB/M003604/1
Source: Self-asserted source
Ian Collinson via DimensionsWizard

BrisSynBio: Bristol Centre for Synthetic Biology

2014-07-30 to 2019-07-29 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, Wiltshire, GB)
GRANT_NUMBER: BB/L01386X/1
Source: Self-asserted source
Ian Collinson via DimensionsWizard

Ensemble and single molecule analysis of protein translocation

2012-01-01 to 2016-01-01 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, Wiltshire, GB)
GRANT_NUMBER: BB/I008675/1
Source: Self-asserted source
Ian Collinson via DimensionsWizard

Defining the mechanistic and functional details of an evolutionarily conserved non-canonical retromer pathway.

Source: Self-asserted source
Ian Collinson via DimensionsWizard

A kinetic and structural analysis of bacterial protein translocation mediated by SecA through SecYEG.

Source: Self-asserted source
Ian Collinson via DimensionsWizard

Bacterial fermentation and large-scale protein production for biophysical analysis.

Source: Self-asserted source
Ian Collinson via DimensionsWizard

A biochemical and biophysical analysis of a ubiquitous protein translocation apparatus

Source: Self-asserted source
Ian Collinson via DimensionsWizard

Analysis of the of the interaction between the SecY protein translocation complex and its substrate pre-protein

Source: Self-asserted source
Ian Collinson via DimensionsWizard

Structural and Functional Analysis of Protein Translocation (P 05)

2003-01-01 to 2005-12-31 | Grant
German Research Foundation (Bonn, DE)
GRANT_NUMBER: 5397556
Source: Self-asserted source
Ian Collinson via DimensionsWizard

Structural studies of the bacterial protein translocase, SecYEG

2002-08-01 to 2004-08-01 | Grant
European Molecular Biology Organization (Heidelberg, DE)
GRANT_NUMBER:

b572099e

Source: Self-asserted source
Ian Collinson via DimensionsWizard

Works (50 of 86)

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Page 1 of 2

Alternative Import-Channels And Destinations Of Mitochondrial PINK1 Controlled By Trans-Membrane-Domain Structural Plasticity

2024-11-06 | Preprint
Contributors: James S. Lorriman; Adam G. Grieve; Robin A. Corey; Ian Collinson
Source: check_circle
Crossref

Whole Cell Luminescence-Based Screen for Inhibitors of the Bacterial Sec Machinery

Biochemistry
2024-09-17 | Journal article
Contributors: Tia Salter; Ian Collinson; William J. Allen
Source: check_circle
Crossref

A whole cell luminescence-based screen for inhibitors of the bacterial Sec machinery

2024-05-10 | Preprint
Contributors: Tia Salter; Ian Collinson; William J. Allen
Source: check_circle
Crossref

Cyclic Ion Mobility for Hydrogen/Deuterium Exchange-Mass Spectrometry Applications

Analytical Chemistry
2024-04-16 | Journal article
Contributors: Damon Griffiths; Malcolm Anderson; Keith Richardson; Satomi Inaba-Inoue; William J. Allen; Ian Collinson; Konstantinos Beis; Michael Morris; Kevin Giles; Argyris Politis
Source: check_circle
Crossref

The consequence of ATP synthase dimer angle on mitochondrial morphology studied by cryo-electron tomography

Biochemical Journal
2024-02-07 | Journal article
Contributors: Emma Buzzard; Mathew McLaren; Piotr Bragoszewski; Andrea Brancaccio; Holly C. Ford; Bertram Daum; Patricia Kuwabara; Ian Collinson; Vicki A.M. Gold
Source: check_circle
Crossref

Rescue of mitochondrial import failure by intercellular organellar transfer

Nature Communications
2024-02-02 | Journal article
Contributors: Hope I. Needs; Emily Glover; Gonçalo C. Pereira; Alina Witt; Wolfgang Hübner; Mark P. Dodding; Jeremy M. Henley; Ian Collinson
Source: check_circle
Crossref

Dynamic coupling of fast channel gating with slow ATP-turnover underpins protein transport through the Sec translocon

The EMBO Journal
2023-12-15 | Journal article
Contributors: Joel A Crossley; William J Allen; Daniel W Watkins; Tara Sabir; Sheena E Radford; Roman Tuma; Ian Collinson; Tomas Fessl
Source: check_circle
Crossref

A unifying mechanism for protein transport through the core bacterial Sec machinery

Open Biology
2023-08 | Journal article
Contributors: William J. Allen; Ian Collinson
Source: check_circle
Crossref

Aggregation-prone Tau impairs mitochondrial import, which affects organelle morphology and neuronal complexity

Journal of Cell Science
2023-07-01 | Journal article
Contributors: Hope I. Needs; Kevin A. Wilkinson; Jeremy M. Henley; Ian Collinson
Source: check_circle
Crossref

Interaction of the periplasmic chaperone SurA with the inner membrane protein secretion (SEC) machinery

Biochemical Journal
2023-02-27 | Journal article
Contributors: Luca A. Troman; Sara Alvira; Bertram Daum; Vicki A. M. Gold; Ian Collinson
Source: check_circle
Crossref

The consequence of ATP synthase dimer angle on mitochondrial morphology studied by cryo-electron tomography

2023-02-03 | Preprint
Contributors: Emma Buzzard; Mathew McLaren; Piotr Bragoszewski; Andrea Brancaccio; Holly Ford; Bertram Daum; Patricia Kuwabara; Ian Collinson; Vicki A.M. Gold
Source: check_circle
Crossref

Intercellular Mitochondrial Transfer as a Rescue Mechanism in Response to Protein Import Failure

2022-12-01 | Preprint
Contributors: Hope I Needs; Gonçalo C. Pereira; Emily Glover; Alina Witt; Wolfgang Hübner; Mark P. Dodding; Jeremy M Henley; Ian Collinson
Source: check_circle
Crossref

Perturbation of the mitochondrial import machinery by aggregation prone Tau affects organelle morphology and reduces neuronal complexity

2022-12-01 | Preprint
Contributors: Hope I Needs; Kevin A Wilkinson; Jeremy M Henley; Ian Collinson
Source: check_circle
Crossref

A bacterial secretosome for regulated envelope biogenesis and quality control?

Microbiology
2022-10-06 | Journal article
Contributors: Daniel W. Watkins; Sophie L. Williams; Ian Collinson
Source: check_circle
Crossref

The NanoLuc Assay System for Accurate Real-Time Monitoring of Mitochondrial Protein Import within Intact Mammalian Cells

2022-09-23 | Preprint
Contributors: Hope I Needs; Gonçalo C. Pereira; Jeremy M Henley; Ian Collinson
Source: check_circle
Crossref

INTERACTION OF THE PERIPLASMIC CHAPERONE SURA WITH THE INNER MEMBRANE PROTEIN SECRETION (SEC) MACHINERY

2022-09-14 | Preprint
Contributors: Lucy Troman; Sara Alvira; Bertram Daum; Vicki A. M. Gold; Ian Collinson
Source: check_circle
Crossref

Towards a molecular mechanism underlying mitochondrial protein import through the TOM and TIM23 complexes

eLife
2022-06-08 | Journal article
Contributors: Holly C Ford; William J Allen; Gonçalo C Pereira; Xia Liu; Mark Simon Dillingham; Ian Collinson
Source: check_circle
Crossref

Rate-limiting transport of positively charged arginine residues through the Sec-machinery is integral to the mechanism of protein secretion

eLife
2022-04-29 | Journal article
Contributors: William J Allen; Robin A Corey; Daniel W Watkins; A Sofia F Oliveira; Kiel Hards; Gregory M Cook; Ian Collinson
Source: check_circle
Crossref

A bacterial secretosome for regulated envelope biogenesis and quality control

2022-01-12 | Preprint
Contributors: Daniel W. Watkins; Ian Collinson
Source: check_circle
Crossref

Towards a molecular mechanism underlying mitochondrial protein import through the TOM and TIM23 complexes

2021-08-31 | Other
Contributors: Holly C. Ford; William J. Allen; Gonçalo C. Pereira; Xia Liu; Mark S. Dillingham; Ian Collinson
Source: check_circle
Crossref

Interplay between Mitochondrial Protein Import and Respiratory Complexes Assembly in Neuronal Health and Degeneration

Life
2021-05-11 | Journal article
Contributors: Hope I. Needs; Margherita Protasoni; Jeremy M. Henley; Julien Prudent; Ian Collinson; Gonçalo C. Pereira
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Genetic Evidence for SecY Translocon-Mediated Import of Two Contact-Dependent Growth Inhibition (CDI) Toxins

mBio
2021-02-23 | Journal article
Contributors: Allison M. Jones; Petra Virtanen; Disa Hammarlöf; William J. Allen; Ian Collinson; Christopher S. Hayes; David A. Low; Sanna Koskiniemi; Kelly T. Hughes
Source: check_circle
Crossref

Membrane protein biogenesis by the EMC

The EMBO Journal
2021-01-15 | Journal article
Contributors: Sara Alvira; Robin A Corey; Ian Collinson; Karin Römisch
Source: check_circle
Crossref

Refined measurement of SecA-driven protein secretion reveals that translocation is indirectly coupled to ATP turnover

Proceedings of the National Academy of Sciences
2020-12-15 | Journal article
Contributors: William J. Allen; Daniel W. Watkins; Mark S. Dillingham; Ian Collinson
Source: check_circle
Crossref

A molecular dual carriageway

eLife
2020-08-25 | Journal article
Contributors: William J Allen; Ian Collinson
Source: check_circle
Crossref

Refined measurement of SecA-driven protein transport reveals indirect coupling to ATP turnover

2020-05-09 | Preprint
Contributors: William J. Allen; Daniel W. Watkins; Mark S. Dillingham; Ian Collinson
Source: check_circle
Crossref

Energy landscape steering mediates dynamic coupling in ATP-driven protein translocation by the bacterial Sec machinery

2019-10-05 | Preprint
Contributors: Joel A. Crossley; William J. Allen; Daniel W. Watkins; Tara Sabir; Sheena E. Radford; Roman Tuma; Ian Collinson; Tomas Fessl
Source: check_circle
Crossref

HDX-MS reveals nucleotide-dependent, anti-correlated opening and closure of SecA and SecY channels of the bacterial translocon

eLife
2019-07-10 | Journal article
Contributors: Zainab Ahdash; Euan Pyle; William John Allen; Robin A Corey; Ian Collinson; Argyris Politis
Source: check_circle
Crossref

A High-Resolution Luminescent Assay for Rapid and Continuous Monitoring of Protein Translocation across Biological Membranes

Journal of Molecular Biology
2019-04 | Journal article
Contributors: Gonçalo C. Pereira; William J. Allen; Daniel W. Watkins; Lisa Buddrus; Dylan Noone; Xia Liu; Andrew P. Richardson; Agnieszka Chacinska; Ian Collinson
Source: check_circle
Crossref

Structure and Dynamics of the Central Lipid Pool and Proteins of the Bacterial Holo-Translocon.

Biophysical journal
2019-04-09 | Journal article
Source: Self-asserted source
Ian Collinson

Post-Translational Protein Transport by the Sec Complex.

Trends in biochemical sciences
2019-04-05 | Journal article
Source: Self-asserted source
Ian Collinson

HDX-MS reveals nucleotide-regulated, anti-correlated opening and closure of SecA and SecY channels of the bacterial translocon

2019-04-01 | Other
Contributors: Zainab Ahdash; Euan Pyle; William J. Allen; Robin A. Corey; Ian Collinson; Argyris Politis
Source: check_circle
Crossref

A ‘proton ratchet’ for coupling the membrane potential to protein transport

2019-03-29 | Preprint
Source: Self-asserted source
Ian Collinson
grade
Preferred source (of 2)‎

Trans-membrane association of the Sec and BAM complexes for bacterial outer-membrane biogenesis

2019-03-27 | Other
Contributors: Sara Alvira; Daniel W. Watkins; Lucy Troman; James Lorriman; Bertram Daum; Vicki A.M. Gold; Ian Collinson
Source: check_circle
Crossref

Effect of Sec61 interaction with Mpd1 on endoplasmic reticulum-associated degradation.

PloS one
2019-01-25 | Journal article
Source: Self-asserted source
Ian Collinson

ATP-induced asymmetric pre-protein folding as a driver of protein translocation through the Sec machinery

eLife
2019-01-02 | Journal article
Contributors: Robin A Corey; Zainab Ahdash; Anokhi Shah; Euan Pyle; William J Allen; Tomas Fessl; Janet E Lovett; Argyris Politis; Ian Collinson
Source: check_circle
Crossref

A High-Resolution Luminescent Assay for Rapid and Continuous Monitoring of Protein Translocation Across Biological Membranes

2018-11-01 | Other
Contributors: Gonçalo C. Pereira; William J. Allen; Daniel W. Watkins; Lisa Buddrus; Dylan Noone; Xia Liu; Andrew Richardson; Agnieszka Chacinska; Ian Collinson
Source: check_circle
Crossref

Specific cardiolipin-SecY interactions are required for proton-motive force stimulation of protein secretion.

Proceedings of the National Academy of Sciences of the United States of America
2018-07-16 | Journal article
Source: Self-asserted source
Ian Collinson

Dynamic action of the Sec machinery during initiation, protein translocation and termination

eLife
2018-06-07 | Journal article
Contributors: Tomas Fessl; Daniel Watkins; Peter Oatley; William John Allen; Robin Adam Corey; Jim Horne; Steve A Baldwin; Sheena E Radford; Ian Collinson; Roman Tuma
Source: check_circle
Crossref

Dynamic action of the Sec machinery during initiation, protein translocation and termination revealed by single molecule fluorescence

2018-01-17 | Other
Contributors: Tomas Fessl; Daniel Watkins; Peter Oatley; William J. Allen; Robin A. Corey; Jim E. Horne; Steve A. Baldwin; Sheena E. Radford; Ian Collinson; Roman Tuma
Source: check_circle
Crossref

ATP-induced asymmetric pre-protein folding: a driver of protein translocation?

2017-10-12 | Other
Contributors: Robin A. Corey; William J. Allen; Ian Collinson
Source: check_circle
Crossref

Specific cardiolipin-SecY interactions are required for proton-motive-force stimulation of protein secretion

2017-10-12 | Other
Contributors: Robin A. Corey; Euan Pyle; William J. Allen; Marina Casiraghi; Bruno Miroux; Ignacio Arechaga; Argyris Politis; Ian Collinson
Source: check_circle
Crossref

The accessory Sec system (SecY2A2) in Streptococcus pneumoniae is involved in export of pneumolysin toxin, adhesion and biofilm formation.

Microbes and infection
2017-04-27 | Journal article
Source: Self-asserted source
Ian Collinson

SecA—a New Twist in the Tale

Journal of Bacteriology
2017-01-15 | Journal article
Contributors: Ian Collinson; T. J. Silhavy
Source: check_circle
Crossref

Multiprotein Complex Production in E. coli: The SecYEG-SecDFYajC-YidC Holotranslocon.

Methods in molecular biology (Clifton, N.J.)
2017-01-01 | Journal article
Source: Self-asserted source
Ian Collinson

A central cavity within the holo-translocon suggests a mechanism for membrane protein insertion.

Scientific reports
2016-12-07 | Journal article
Source: Self-asserted source
Ian Collinson

Composition and Activity of the Non-canonical Gram-positive SecY2 Complex.

The Journal of biological chemistry
2016-08-22 | Journal article
Source: Self-asserted source
Ian Collinson

Protein translocation: what's the problem?

Biochemical Society transactions
2016-06-01 | Journal article
Source: Self-asserted source
Ian Collinson

Two-way communication between SecY and SecA suggests a Brownian ratchet mechanism for protein translocation

eLife
2016-05-16 | Journal article
Contributors: William John Allen; Robin Adam Corey; Peter Oatley; Richard Barry Sessions; Steve A Baldwin; Sheena E Radford; Roman Tuma; Ian Collinson
Source: check_circle
Crossref

Unlocking the Bacterial SecY Translocon.

Structure (London, England : 1993)
2016-03-10 | Journal article
Source: Self-asserted source
Ian Collinson
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