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Cyclooxygenase-2/prostaglandin E2 inhibition remodulated photodynamic therapy-associated immunosuppression for enhanced cancer immunotherapy

Materials Today Bio
2025-04 | Journal article
DOI: 10.1016/j.mtbio.2025.101530
Contributors: Tao Xu; Kehan Liu; Shuqi Mi; Yao Yao; Mengyao Zhang; Shujuan Xue; Feng Zhi; Sally-Ann Cryan; Dawei Ding
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Compositional Influence of Cross‐linked Polyion Hydrogels from Poly(L‐Lysine) and Poly(L‐Glutamic Acid) on Their Properties for Potential Skin Applications

Macromolecular Chemistry and Physics
2024-10 | Journal article
DOI: 10.1002/macp.202400201
Contributors: Rafał Bielas; Sarinj Fattah; Łukasz Mielańczyk; German Pozdeev; Sally‐Ann Cryan; Andreas Heise
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Microfluidics produced ATRA-loaded PLGA NPs reduced tuberculosis burden in alveolar epithelial cells and enabled high delivered dose under simulated human breathing pattern in 3D printed head models

European Journal of Pharmaceutical Sciences
2024-05 | Journal article
DOI: 10.1016/j.ejps.2024.106734
Contributors: Ahmad Z. Bahlool; Brenton Cavanagh; Andrew O’ Sullivan; Ronan MacLoughlin; Joseph Keane; Mary P O’ Sullivan; Sally-Ann Cryan
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Optimizing the Delivery of mRNA to Mesenchymal Stem Cells for Tissue Engineering Applications

Molecular Pharmaceutics
2024-04-01 | Journal article
DOI: 10.1021/acs.molpharmaceut.3c00898
Contributors: Katie McCormick; Jorge Moreno Herrero; Heinrich Haas; Sarinj Fattah; Andreas Heise; Fergal J. O’Brien; Sally-Ann Cryan
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Star-shaped poly(l-lysine) with polyester bis-MPA dendritic core as potential degradable nano vectors for gene delivery

Polymer Chemistry
2023 | Journal article
DOI: 10.1039/D3PY00346A
Contributors: Smiljana Stefanovic; Katie McCormick; Sarinj Fattah; Ruiari Brannigan; Sally-Ann Cryan; Andreas Heise
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All trans retinoic acid as a host-directed immunotherapy for tuberculosis

Current Research in Immunology
2022 | Journal article
DOI: 10.1016/j.crimmu.2022.03.003
EID:

2-s2.0-85132308781

Part of ISSN: 25902555
Contributors: Bahlool, A.Z.; Grant, C.; Cryan, S.-A.; Keane, J.; O'Sullivan, M.P.
Source: Self-asserted source
Sally-Ann Cryan via Scopus - Elsevier

Development of Inhalable ATRA-Loaded PLGA Nanoparticles as Host-Directed Immunotherapy against Tuberculosis

Pharmaceutics
2022 | Journal article
DOI: 10.3390/pharmaceutics14081745
EID:

2-s2.0-85137407794

Part of ISSN: 19994923
Contributors: Bahlool, A.Z.; Fattah, S.; O’Sullivan, A.; Cavanagh, B.; MacLoughlin, R.; Keane, J.; O’Sullivan, M.P.; Cryan, S.-A.
Source: Self-asserted source
Sally-Ann Cryan via Scopus - Elsevier

Enhancing arginase 2 expression using target site blockers as a strategy to modulate macrophage phenotype

Molecular Therapy - Nucleic Acids
2022 | Journal article
DOI: 10.1016/j.omtn.2022.08.004
EID:

2-s2.0-85136605128

Part of ISSN: 21622531
Contributors: De Santi, C.; Nally, F.K.; Afzal, R.; Duffy, C.P.; Fitzsimons, S.; Annett, S.L.; Robson, T.; Dowling, J.K.; Cryan, S.-A.; McCoy, C.E.
Source: Self-asserted source
Sally-Ann Cryan via Scopus - Elsevier

Exploring the potential of polypeptide–polypeptoide hybrid nanogels for mucosal delivery

Polymer Chemistry
2022 | Journal article
DOI: 10.1039/D2PY01126C
Contributors: Tao Xu; Dimitrios Skoulas; Dawei Ding; Sally-Ann Cryan; Andreas Heise
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Systematic Study of Enzymatic Degradation and Plasmid DNA Complexation of Mucus Penetrating Star‐Shaped Lysine/Sarcosine Polypept(o)ides with Different Block Arrangements

Macromolecular Bioscience
2022-08 | Journal article
DOI: 10.1002/mabi.202200175
Contributors: Dimitrios Skoulas; Sarinj Fattah; Dandan Wang; Sally‐Ann Cryan; Andreas Heise
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Ion-Triggered Hydrogels Self-Assembled from Statistical Copolypeptides

ACS Macro Letters
2022-03-15 | Journal article
DOI: 10.1021/acsmacrolett.1c00774
Contributors: Bing Wu; Saltuk B. Hanay; Scott D. Kimmins; Sally-Ann Cryan; Daniel Hermida Merino; Andreas Heise
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Modified poly(L-lysine)-based structures as novel antimicrobials for diabetic foot infections, an <i>in-vitro</i> study.

HRB open research
2022-01 | Journal article
DOI: 10.12688/hrbopenres.13380.1
PMID: 36017374
PMC: PMC9366240
Contributors: Grace A; Murphy R; Dillon A; Smith D; Cryan SA; Heise A; Fitzgerald-Hughes D
Source: Self-asserted source
Sally-Ann Cryan via Europe PubMed Central

A tissue-engineered tracheobronchial in vitro co-culture model for determining epithelial toxicological and inflammatory responses

Biomedicines
2021 | Journal article
DOI: 10.3390/biomedicines9060631
EID:

2-s2.0-85107760145

Part of ISSN: 22279059
Contributors: Soriano, L.; Khalid, T.; O’Brien, F.J.; O’Leary, C.; Cryan, S.-A.
Source: Self-asserted source
Sally-Ann Cryan via Scopus - Elsevier

An automated culture system for use in preclinical testing of host-directed therapies for tuberculosis

Journal of Visualized Experiments
2021 | Journal article
DOI: 10.3791/62838
EID:

2-s2.0-85114286270

Part of ISSN: 1940087X
Contributors: O’leary, S.; Bahlool, A.Z.; O’connor, G.; Cryan, S.-A.; Keane, J.M.; O’sullivan, M.P.
Source: Self-asserted source
Sally-Ann Cryan via Scopus - Elsevier

Antimicrobial and degradable triazolinedione (TAD) crosslinked polypeptide hydrogels

Journal of Materials Chemistry B
2021 | Journal article
DOI: 10.1039/D1TB00776A
Contributors: Scott D. Kimmins; Saltuk B. Hanay; Robert Murphy; Joanne O’Dwyer; Jessica Ramalho; Emily J. Ryan; Cathal J. Kearney; Fergal J. O'Brien; Sally-Ann Cryan; Deirdre Fitzgerald-Hughes et al.
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Development and clinical translation of tubular constructs for tracheal tissue engineering: A review

European Respiratory Review
2021 | Journal article
DOI: 10.1183/16000617.0154-2021
EID:

2-s2.0-85121425080

Part of ISSN: 16000617 09059180
Contributors: Soriano, L.; Khalid, T.; Whelan, D.; O’huallachain, N.; Redmond, K.C.; O’brien, F.J.; O’leary, C.; Cryan, S.-A.
Source: Self-asserted source
Sally-Ann Cryan via Scopus - Elsevier

Development of collagen-poly(caprolactone)-based core-shell scaffolds supplemented with proteoglycans and glycosaminoglycans for ligament repair

Materials Science and Engineering C
2021 | Journal article
DOI: 10.1016/j.msec.2020.111657
EID:

2-s2.0-85095596759

Part of ISSN: 18730191 09284931
Contributors: Gouveia, P.J.; Hodgkinson, T.; Amado, I.; Sadowska, J.M.; Ryan, A.J.; Romanazzo, S.; Carroll, S.; Cryan, S.-A.; Kelly, D.J.; O'Brien, F.J.
Source: Self-asserted source
Sally-Ann Cryan via Scopus - Elsevier

Gene activated scaffolds incorporating star-shaped polypeptide-pDNA nanomedicines accelerate bone tissue regeneration in vivo

Biomaterials Science
2021 | Journal article
DOI: 10.1039/D1BM00094B
Contributors: David P. Walsh; Rosanne M. Raftery; Robert Murphy; Gang Chen; Andreas Heise; Fergal J. O'Brien; Sally-Ann Cryan
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Three-dimensionally printable shear-thinning triblock copolypeptide hydrogels with antimicrobial potency

Biomaterials Science
2021 | Journal article
DOI: 10.1039/D1BM00275A
Contributors: Robert Murphy; Shadi Kordbacheh; Dimitrios Skoulas; Simon Ng; Kasinan Suthiwanich; Andrea M. Kasko; Sally-Ann Cryan; Deirdre Fitzgerald-Hughes; Ali Khademhosseini; Amir Sheikhi et al.
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Translational studies on the potential of a vegf nanoparticle-loaded hyaluronic acid hydrogel

Pharmaceutics
2021 | Journal article
DOI: 10.3390/pharmaceutics13060779
EID:

2-s2.0-85107286394

Part of ISSN: 19994923
Contributors: O’dwyer, J.; Murphy, R.; González-Vázquez, A.; Kovarova, L.; Pravda, M.; Velebny, V.; Heise, A.; Duffy, G.P.; Cryan, S.A.
Source: Self-asserted source
Sally-Ann Cryan via Scopus - Elsevier

Cardiac responses to biomaterials

Handbook of Biomaterials Biocompatibility
2020 | Book chapter
Part of DOI: 10.1016/B978-0-08-102967-1.00025-6
EID:

2-s2.0-85115939696
Contributors: O’Dwyer, J.; Wylie, R.; Cryan, S.A.; Duffy, G.P.; Dolan, E.B.
Source: Self-asserted source
Sally-Ann Cryan via Scopus - Elsevier

Corrigendum to “Transfection of autologous host cells in vivo using gene activated collagen scaffolds incorporating star-polypeptides” (Journal of Controlled Release (2019) 304 (191–203), (S0168365919302573), (10.1016/j.jconrel.2019.05.009))

Journal of Controlled Release
2020 | Journal article
DOI: 10.1016/j.jconrel.2020.01.025
EID:

2-s2.0-85078113982

Part of ISBN:

18734995 01683659
Contributors: Walsh, D.P.; Raftery, R.M.; Castaño, I.M.; Murphy, R.; Cavanagh, B.; Heise, A.; O'Brien, F.J.; Cryan, S.-A.
Source: Self-asserted source
Sally-Ann Cryan via Scopus - Elsevier

Development of a sustained release nano-in-gel delivery system for the chemotactic and angiogenic growth factor stromal-derived factor 1α

Pharmaceutics
2020 | Journal article
DOI: 10.3390/pharmaceutics12060513
EID:

2-s2.0-85088981880

Part of ISBN:

19994923
Contributors: O’Dwyer, J.; Cullen, M.; Fattah, S.; Murphy, R.; Stefanovic, S.; Kovarova, L.; Pravda, M.; Velebny, V.; Heise, A.; Duffy, G.P. et al.
Source: Self-asserted source
Sally-Ann Cryan via Scopus - Elsevier

In vitro and in vivo assessment of pegylated pei for anti-il-8/cxcl-1 sirna delivery to the lungs

Nanomaterials
2020 | Journal article
DOI: 10.3390/nano10071248
EID:

2-s2.0-85087112206

Part of ISBN:

20794991
Contributors: Hibbitts, A.J.; Ramsey, J.M.; Barlow, J.; Macloughlin, R.; Cryan, S.-A.
Source: Self-asserted source
Sally-Ann Cryan via Scopus - Elsevier

Precise Targeting of miRNA Sites Restores CFTR Activity in CF Bronchial Epithelial Cells

Molecular Therapy
2020 | Journal article
DOI: 10.1016/j.ymthe.2020.02.001
EID:

2-s2.0-85079408928

Part of ISBN:

15250024 15250016
Contributors: De Santi, C.; Fernández Fernández, E.; Gaul, R.; Vencken, S.; Glasgow, A.; Oglesby, I.K.; Hurley, K.; Hawkins, F.; Mitash, N.; Mu, F. et al.
Source: Self-asserted source
Sally-Ann Cryan via Scopus - Elsevier

Respiratory Drug/Vaccine Delivery Using Nanoparticles

AAPS Advances in the Pharmaceutical Sciences Series
2020 | Book chapter
DOI: 10.1007/978-3-030-35910-2_6
EID:

2-s2.0-85090041879

Part of ISSN: 2210738X 22107371
Contributors: Ramsey, J.M.; McCloskey, A.; Gaul, R.; Fernandez, E.F.; Sweeney, L.; Greene, C.M.; Macloughlin, R.; Cryan, S.-A.
Source: Self-asserted source
Sally-Ann Cryan via Scopus - Elsevier

The Fabrication and in vitro Evaluation of Retinoic Acid-Loaded Electrospun Composite Biomaterials for Tracheal Tissue Regeneration

Frontiers in Bioengineering and Biotechnology
2020 | Journal article
DOI: 10.3389/fbioe.2020.00190
EID:

2-s2.0-85083029756

Part of ISBN:

22964185
Contributors: O'Leary, C.; Soriano, L.; Fagan-Murphy, A.; Ivankovic, I.; Cavanagh, B.; O'Brien, F.J.; Cryan, S.-A.
Source: Self-asserted source
Sally-Ann Cryan via Scopus - Elsevier

Biocompatible polypeptide-based interpenetrating network (IPN) hydrogels with enhanced mechanical properties.

Journal of materials chemistry. B
2020-08 | Journal article
DOI: 10.1039/d0tb01422b
PMID: 32744280
Contributors: O'Brien S; Brannigan RP; Ibanez R; Wu B; O'Dwyer J; O'Brien FJ; Cryan SA; Heise A
Source: Self-asserted source
Sally-Ann Cryan via Europe PubMed Central
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Amphiphilic Star Polypept(o)ides as Nanomeric Vectors in Mucosal Drug Delivery

Biomacromolecules
2020-06-08 | Journal article
DOI: 10.1021/acs.biomac.0c00381
Contributors: Dimitrios Skoulas; Vivien Stuettgen; Rachel Gaul; Sally-Ann Cryan; David J. Brayden; Andreas Heise
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Development of a nanomedicine-loaded hydrogel for sustained delivery of an angiogenic growth factor to the ischaemic myocardium

Drug Delivery and Translational Research
2020-04-05 | Journal article
DOI: 10.1007/s13346-019-00684-5
Contributors: Joanne O’Dwyer; Robert Murphy; Eimear B. Dolan; Lenka Kovarova; Martin Pravda; Vladimir Velebny; Andreas Heise; Garry P. Duffy; Sally Ann Cryan
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Anisotropic polymer nanoparticles with solvent and temperature dependent shape and size from triblock copolymers

Polymer Chemistry
2019 | Journal article
DOI: 10.1039/C9PY00363K
Contributors: Elena Bobbi; Bassem Sabagh; Sally-Ann Cryan; James A. Wilson; Andreas Heise
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Effective nebulization of interferon-γ using a novel vibrating mesh

Respiratory Research
2019 | Journal article
DOI: 10.1186/s12931-019-1030-1
EID:

2-s2.0-85063934436
Contributors: Sweeney, L.; McCloskey, A.P.; Higgins, G.; Ramsey, J.M.; Cryan, S.-A.; MacLoughlin, R.
Source: Self-asserted source
Sally-Ann Cryan via Scopus - Elsevier

Evaluation of the Immunomodulatory Effects of All-Trans Retinoic Acid Solid Lipid Nanoparticles and Human Mesenchymal Stem Cells in an A549 Epithelial Cell Line Model

Pharmaceutical Research
2019 | Journal article
DOI: 10.1007/s11095-019-2583-x
EID:

2-s2.0-85061603351
Contributors: Payne, C.M.; Burke, L.P.; Cavanagh, B.; O’Toole, D.; Cryan, S.-A.; Kelly, H.M.
Source: Self-asserted source
Sally-Ann Cryan via Scopus - Elsevier

Inhalable poly(lactic-co-glycolic acid) (PLGA) microparticles encapsulating all-trans-Retinoic acid (ATRA) as a host-directed, adjunctive treatment for Mycobacterium tuberculosis infection

European Journal of Pharmaceutics and Biopharmaceutics
2019 | Journal article
DOI: 10.1016/j.ejpb.2018.10.020
EID:

2-s2.0-85057807225
Contributors: O'Connor, G.; Krishnan, N.; Fagan-Murphy, A.; Cassidy, J.; O'Leary, S.; Robertson, B.D.; Keane, J.; O'Sullivan, M.P.; Cryan, S.-A.
Source: Self-asserted source
Sally-Ann Cryan via Scopus - Elsevier

Nebulised lipid-polymer hybrid nanoparticles for the delivery of a therapeutic anti-inflammatory microRNA to bronchial epithelial cells

ERS Monograph
2019 | Journal article
DOI: 10.1183/23120541.00161-2018
EID:

2-s2.0-85065996059
Contributors: Vencken, S.; Foged, C.; Ramsey, J.M.; Sweeney, L.; Cryan, S.-A.; MacLoughlin, R.J.; Greene, C.M.
Source: Self-asserted source
Sally-Ann Cryan via Scopus - Elsevier

Rapid healing of a critical‐sized bone defect using a collagen‐hydroxyapatite scaffold to facilitate low dose, combinatorial growth factor delivery

Journal of Tissue Engineering and Regenerative Medicine
2019-10-08 | Journal article
DOI: 10.1002/term.2934
Contributors: David P. Walsh; Rosanne M. Raftery; Gang Chen; Andreas Heise; Fergal J. O'Brien; Sally‐Ann Cryan
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Gelating polypeptide matrices based on the difunctional N‐carboxyanhydride diaminopimelic acid cross‐linker

Journal of Polymer Science Part A: Polymer Chemistry
2019-06 | Journal article
DOI: 10.1002/pola.29376
Contributors: Robert D. Murphy; Elena Bobbi; Fernando C. S. de Oliveira; Sally‐Ann Cryan; Andreas Heise
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Transfection of autologous host cells in vivo using gene activated collagen scaffolds incorporating star-polypeptides

Journal of Controlled Release
2019-06 | Journal article
DOI: 10.1016/j.jconrel.2019.05.009
Contributors: David P. Walsh; Rosanne M. Raftery; Irene Mencía Castaño; Robert Murphy; Brenton Cavanagh; Andreas Heise; Fergal J. O'Brien; Sally-Ann Cryan
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Poly(ethylene glycol)-Based Peptidomimetic “PEGtide” of Oligo-Arginine Allows for Efficient siRNA Transfection and Gene Inhibition

ACS Omega
2019-06-30 | Journal article
DOI: 10.1021/acsomega.9b00265
Contributors: Alan Hibbitts; Aoife M. O’Connor; Joanna McCarthy; Éanna B. Forde; Gary Hessman; Caitriona M. O’Driscoll; Sally-Ann Cryan; Marc Devocelle
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A Novel Methodology for Bio-electrospraying Mesenchymal Stem Cells that Maintains Differentiation, Immunomodulatory and Pro-reparative Functions

Journal of Medical and Biological Engineering
2018 | Journal article
DOI: 10.1007/s40846-017-0331-4
EID:

2-s2.0-85047266333
Contributors: McCrea, Z.; Arnanthigo, Y.; Cryan, S.-A.; O’Dea, S.
Source: Self-asserted source
Sally-Ann Cryan via Scopus - Elsevier

Disulphide crosslinked star block copolypeptide hydrogels: influence of block sequence order on hydrogel properties

Polymer Chemistry
2018 | Journal article
DOI: 10.1039/C8PY00741A
Contributors: Robert D. Murphy; Marc in het Panhuis; Sally-Ann Cryan; Andreas Heise
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Nanotechnology approaches to pulmonary drug delivery: Targeted delivery of small molecule and gene-based therapeutics to the lung

Design of Nanostructures for Versatile Therapeutic Applications
2018 | Book
Part of DOI: 10.1016/B978-0-12-813667-6.00006-1
EID:

2-s2.0-85047417303
Contributors: Gaul, R.; Ramsey, J.M.; Heise, A.; Cryan, S.-A.; Greene, C.M.
Source: Self-asserted source
Sally-Ann Cryan via Scopus - Elsevier

Knockdown of Gene Expression in Macrophages by microRNA Mimic-Containing Poly (Lactic-co-glycolic Acid) Microparticles.

Medicines (Basel, Switzerland)
2018-12 | Journal article
DOI: 10.3390/medicines5040133
PMID: 30558310
PMC: PMC6313440
Contributors: McKiernan PJ; Lynch P; Ramsey JM; Cryan SA; Greene CM
Source: Self-asserted source
Sally-Ann Cryan via Europe PubMed Central

Facile Approach to Covalent Copolypeptide Hydrogels and Hybrid Organohydrogels

ACS Macro Letters
2018-08-21 | Journal article
DOI: 10.1021/acsmacrolett.8b00431
Contributors: Saltuk B. Hanay; Joanne O’Dwyer; Scott D. Kimmins; Fernando C. S. de Oliveira; Matthew G. Haugh; Fergal J. O’Brien; Sally-Ann Cryan; Andreas Heise
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Degradable 3D-Printed Hydrogels Based on Star-Shaped Copolypeptides

Biomacromolecules
2018-07-09 | Journal article
DOI: 10.1021/acs.biomac.8b00299
Contributors: Robert Murphy; David P. Walsh; Charles A. Hamilton; Sally-Ann Cryan; Marc in het Panhuis; Andreas Heise
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Bioinspired Star-Shaped Poly(l-lysine) Polypeptides: Efficient Polymeric Nanocarriers for the Delivery of DNA to Mesenchymal Stem Cells

Molecular Pharmaceutics
2018-05-07 | Journal article
DOI: 10.1021/acs.molpharmaceut.8b00044
Contributors: David P. Walsh; Robert D. Murphy; Angela Panarella; Rosanne M. Raftery; Brenton Cavanagh; Jeremy C. Simpson; Fergal J. O’Brien; Andreas Heise; Sally-Ann Cryan
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Biopolymer-Based Nanoparticles for Cystic Fibrosis Lung Gene Therapy Studies.

Materials (Basel, Switzerland)
2018-01 | Journal article
DOI: 10.3390/ma11010122
PMID: 29342838
Contributors: Fernández Fernández E; Santos-Carballal B; de Santi C; Ramsey JM; MacLoughlin R; Cryan SA; Greene CM
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Sally-Ann Cryan via Europe PubMed Central
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A methylcellulose and collagen based temperature responsive hydrogel promotes encapsulated stem cell viability and proliferation in vitro

Drug Delivery and Translational Research
2017 | Journal article
DOI: 10.1007/s13346-016-0347-2
EID:

2-s2.0-85009770824
Contributors: Payne, C.; Dolan, E.B.; O’Sullivan, J.; Cryan, S.-A.; Kelly, H.M.
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Sally-Ann Cryan via Scopus - Elsevier

Anti-GD2-ch14.18/CHO coated nanoparticles mediate glioblastoma (GBM)-specific delivery of the aromatase inhibitor, Letrozole, reducing proliferation, migration and chemoresistance in patientderived GBM tumor cells

Oncotarget
2017 | Journal article
DOI: 10.18632/oncotarget.15073
EID:

2-s2.0-85014715609
Contributors: Tivnan, A.; Heilinger, T.; Ramsey, J.M.; O'Connor, G.; Pokorny, J.L.; Sarkaria, J.N.; Stringer, B.W.; Day, B.W.; Boyd, A.W.; Kim, E.L. et al.
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Sally-Ann Cryan via Scopus - Elsevier

Controlled release of vascular endothelial growth factor from spray-dried alginate microparticles in collagen–hydroxyapatite scaffolds for promoting vascularization and bone repair

Journal of Tissue Engineering and Regenerative Medicine
2017 | Journal article
DOI: 10.1002/term.2013
EID:

2-s2.0-85017199633
Contributors: Quinlan, E.; López-Noriega, A.; Thompson, E.M.; Hibbitts, A.; Cryan, S.A.; O'Brien, F.J.
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Sally-Ann Cryan via Scopus - Elsevier
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Peer review (2 reviews for 2 publications/grants)

Review activity for Drug delivery and translational research. (1)
Review activity for Molecular pharmaceutics. (1)
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