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Institute of Molecular Genetics: Prague, Bohemia, CZ

2017-05-01 to present | Director of the Institute, Head of Department (Department of Signal Transduction)
Employment
Source: Self-asserted source
Petr Draber

Works (50 of 153)

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Page 1 of 4

Simplified PCR-Based Quantification of Proteins with DNA Aptamers and Methylcellulose as a Blocking Agent

International Journal of Molecular Sciences
2023-12-26 | Journal article
DOI: 10.3390/ijms25010347
Part of ISSN: 1422-0067
Contributors: Oleksij Redcenko; Magda Tumova; Petr Draber
Source: Self-asserted source
Petr Draber

Enhanced Membrane Fluidization and Cholesterol Displacement by 1-Heptanol Inhibit Mast Cell Effector Functions

Cells
2023-08-15 | Journal article
DOI: 10.3390/cells12162069
Contributors: Viktor Bugajev; Lubica Draberova; Pavol Utekal; Michaela Blazikova; Magda Tumova; Petr Draber
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Simultaneous reduction of all ORMDL proteins decreases the threshold of mast cell activation

Scientific Reports
2023-06-14 | Journal article
DOI: 10.1038/s41598-023-36344-5
Contributors: Livia Demkova; Viktor Bugajev; Pavol Utekal; Ladislav Kuchar; Björn Schuster; Petr Draber; Ivana Halova
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Crossref

Pentacyclic triterpenoid ursolic acid interferes with mast cell activation via a lipid-centric mechanism affecting FcεRI signalosome functions

Journal of Biological Chemistry
2022 | Journal article
DOI: 10.1016/j.jbc.2022.102497
EID:

2-s2.0-85140254673

Part of ISSN: 1083351X 00219258
Contributors: Shaik, G.M.; Draberova, L.; Cernohouzova, S.; Tumova, M.; Bugajev, V.; Draber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Crosstalk between ORMDL3, serine palmitoyltransferase, and 5-lipoxygenase in the sphingolipid and eicosanoid metabolic pathways

Journal of Lipid Research
2021 | Journal article
DOI: 10.1016/J.JLR.2021.100121
EID:

2-s2.0-85118308975

Part of ISSN: 15397262 00222275
Contributors: Bugajev, V.; Paulenda, T.; Utekal, P.; Mrkacek, M.; Halova, I.; Kuchar, L.; Kuda, O.; Vavrova, P.; Schuster, B.; Fuentes-Liso, S. et al.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Molecular Mechanisms of Mast Cell Activation by Cholesterol-Dependent Cytolysins

Frontiers in Immunology
2021 | Journal article
DOI: 10.3389/fimmu.2021.670205
EID:

2-s2.0-85109155490

Part of ISSN: 16643224
Contributors: Draberova, L.; Tumova, M.; Draber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

ORMDL2 Deficiency Potentiates the ORMDL3-Dependent Changes in Mast Cell Signaling

Frontiers in Immunology
2021 | Journal article
DOI: 10.3389/fimmu.2020.591975
EID:

2-s2.0-85101866133

Part of ISSN: 16643224
Contributors: Bugajev, V.; Halova, I.; Demkova, L.; Cernohouzova, S.; Vavrova, P.; Mrkacek, M.; Utekal, P.; Draberova, L.; Kuchar, L.; Schuster, B. et al.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Carboxymethylcellulose enhances the production of single-stranded DNA aptamers generated by asymmetric PCR

Analytical Biochemistry
2020 | Journal article
DOI: 10.1016/j.ab.2019.113502
EID:

2-s2.0-85074671789

Part of ISSN: 10960309 00032697
Contributors: Redcenko, O.; Draberova, L.; Draber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Cytoskeletal Protein 4.1R Is a Positive Regulator of the FcεRI Signaling and Chemotaxis in Mast Cells

Frontiers in Immunology
2020 | Journal article
DOI: 10.3389/fimmu.2019.03068
EID:

2-s2.0-85078688527

Part of ISSN: 16643224
Contributors: Draberova, L.; Draberova, H.; Potuckova, L.; Halova, I.; Bambouskova, M.; Mohandas, N.; Draber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Mast cell migration and chemotaxis assayed by microscopy

Methods in Molecular Biology
2020 | Book chapter
DOI: 10.1007/978-1-0716-0696-4_24
EID:

2-s2.0-85089300985

Part of ISSN: 19406029 10643745
Contributors: Bambousková, M.; Rubíková, Z.; Dráberová, L.; Dráber, P.; Dráber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Triacylglycerol-Rich Oils of Marine Origin are Optimal Nutrients for Induction of Polyunsaturated Docosahexaenoic Acid Ester of Hydroxy Linoleic Acid (13-DHAHLA) with Anti-Inflammatory Properties in Mice

Molecular Nutrition and Food Research
2020 | Journal article
DOI: 10.1002/mnfr.201901238
EID:

2-s2.0-85084156610

Part of ISSN: 16134133 16134125
Contributors: Paluchova, V.; Vik, A.; Cajka, T.; Brezinova, M.; Brejchova, K.; Bugajev, V.; Draberova, L.; Draber, P.; Buresova, J.; Kroupova, P. et al.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Tetraspanins in the regulation of mast cell function

Medical Microbiology and Immunology
2020-08 | Journal article
DOI: 10.1007/s00430-020-00679-x
Contributors: Zane Orinska; Philipp M. Hagemann; Ivana Halova; Petr Draber
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Positive and negative regulatory roles of C-terminal Src kinase (CSK) in FceRI-mediated mast cell activation, independent of the transmembrane adaptor PAG/CSK-binding protein

Frontiers in Immunology
2018 | Journal article
DOI: 10.3389/fimmu.2018.01771
EID:

2-s2.0-85051113270

Part of ISSN: 16643224
Contributors: Potuckova, L.; Draberova, L.; Halova, I.; Paulenda, T.; Draber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

The transmembrane adaptor protein NTAL limits mast cell chemotaxis toward prostaglandin E 2

Science Signaling
2018-11-13 | Journal article
DOI: 10.1126/scisignal.aao4354
Contributors: Ivana Halova; Monika Bambouskova; Lubica Draberova; Viktor Bugajev; Petr Draber
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Changing the threshold—Signals and mechanisms of mast cell priming

Immunological Reviews
2018-03 | Journal article
DOI: 10.1111/imr.12625
Contributors: Ivana Halova; Elin Rönnberg; Lubica Draberova; Harissios Vliagoftis; Gunnar P. Nilsson; Petr Draber
Source: check_circle
Crossref
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Positive and Negative Signals in Mast Cell Activation

Trends in Immunology
2017 | Journal article
DOI: 10.1016/j.it.2017.01.008
EID:

2-s2.0-85013093625

Part of ISSN: 14714981 14714906
Contributors: Bulfone-Paus, S.; Nilsson, G.; Draber, P.; Blank, U.; Levi-Schaffer, F.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Negative regulatory roles of ORMDL3 in the FcεRI-triggered expression of proinflammatory mediators and chemotactic response in murine mast cells

Cellular and Molecular Life Sciences
2016 | Journal article
DOI: 10.1007/s00018-015-2047-3
EID:

2-s2.0-84958811543

Part of ISSN: 14209071 1420682X
Contributors: Bugajev, V.; Halova, I.; Draberova, L.; Bambouskova, M.; Potuckova, L.; Draberova, H.; Paulenda, T.; Junyent, S.; Draber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

New regulatory roles of galectin-3 in high-affinity IgE receptor signaling

Molecular and Cellular Biology
2016 | Journal article
DOI: 10.1128/MCB.00064-16
EID:

2-s2.0-84965140052

Part of ISSN: 10985549 02707306
Contributors: Bambouskova, M.; Polakovicova, I.; Halova, I.; Goel, G.; Draberova, L.; Bugajev, V.; Doan, A.; Utekal, P.; Gardet, A.; Xavier, R.J. et al.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Signal transduction and chemotaxis in mast cells

European Journal of Pharmacology
2016 | Journal article
DOI: 10.1016/j.ejphar.2015.02.057
EID:

2-s2.0-84929646112

Part of ISSN: 18790712 00142999
Contributors: Draber, P.; Halova, I.; Polakovicova, I.; Kawakami, T.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Tetraspanins and transmembrane adaptor proteins as plasma membrane organizers-mast cell case

Frontiers in Cell and Developmental Biology
2016 | Journal article
DOI: 10.3389/fcell.2016.00043
EID:

2-s2.0-85011722980

Part of ISSN: 2296634X
Contributors: Halova, I.; Draber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

The role of ORMDL proteins, guardians of cellular sphingolipids, in asthma

Allergy: European Journal of Allergy and Clinical Immunology
2016 | Journal article
DOI: 10.1111/all.12877
EID:

2-s2.0-84963628587

Part of ISSN: 13989995 01054538
Contributors: Paulenda, T.; Draber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Ethanol inhibits high-Affinity immunoglobulin e receptor (FcεRI) signaling in mast cells by suppressing the function of FcεRI-cholesterol signalosome

PLoS ONE
2015 | Journal article
DOI: 10.1371/journal.pone.0144596
EID:

2-s2.0-84957109946

Part of ISSN: 19326203
Contributors: Draberova, L.; Paulenda, T.; Halova, I.; Potuckova, L.; Bugajev, V.; Bambouskova, M.; Tumova, M.; Draber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Membrane-Cytoskeleton dynamics in the course of mast cell activation

Methods in Molecular Biology
2015 | Book
DOI: 10.1007/978-1-4939-1568-2_14
EID:

2-s2.0-84954598051

Part of ISSN: 10643745
Contributors: Dráber, P.; Dráber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Real-time PCR-based genotyping from whole blood using Taq DNA polymerase and a buffer supplemented with 1,2-propanediol and trehalose

Journal of Immunological Methods
2015 | Journal article
DOI: 10.1016/j.jim.2014.09.006
EID:

2-s2.0-84922200105

Part of ISSN: 18727905 00221759
Contributors: Utekal, P.; Kocanda, L.; Matousek, P.; Wagner, P.; Bugajev, V.; Draber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Gold nanoparticle-based immuno-PCR for detection of tau protein in cerebrospinal fluid

Journal of Immunological Methods
2014 | Journal article
DOI: 10.1016/j.jim.2014.03.007
EID:

2-s2.0-84900841524

Part of ISSN: 18727905 00221759
Contributors: Stegurová, L.; Dráberová, E.; Bartos, A.; Dráber, P.; Řípová, D.; Dráber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Microscopy assays for evaluation of mast cell Migration and Chemotaxis

Methods in Molecular Biology
2014 | Book
DOI: 10.1007/978-1-4939-1173-8_12
EID:

2-s2.0-84927554354

Part of ISSN: 10643745
Contributors: Bambousková, M.; Hájková, Z.; Dráber, P.; Dráber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Molecular targets on mast cells and basophils for novel therapies

Journal of Allergy and Clinical Immunology
2014 | Journal article
DOI: 10.1016/j.jaci.2014.03.007
EID:

2-s2.0-84906945203

Part of ISSN: 10976825 00916749
Contributors: Harvima, I.T.; Levi-Schaffer, F.; Draber, P.; Friedman, S.; Polakovicova, I.; Gibbs, B.F.; Blank, U.; Nilsson, G.; Maurer, M.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Multiple regulatory roles of the mouse transmembrane adaptor protein NTAL in gene transcription and mast cell physiology

PLoS ONE
2014 | Journal article
DOI: 10.1371/journal.pone.0105539
EID:

2-s2.0-84928487830

Part of ISSN: 19326203
Contributors: Polakovicova, I.; Draberova, L.; Simicek, M.; Draber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Transmembrane adaptor protein PAG/CBP is involved in both positive and negative regulation of mast cell signaling

Molecular and Cellular Biology
2014 | Journal article
DOI: 10.1128/MCB.00983-14
EID:

2-s2.0-84909587164

Part of ISSN: 10985549 02707306
Contributors: Draberova, L.; Bugajev, V.; Potuckova, L.; Halova, I.; Bambouskova, M.; Polakovicova, I.; Xavier, R.J.; Seed, B.; Drabera, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Cross-talk between tetraspanin CD9 and transmembrane adaptor protein non-T cell activation linker (NTAL) in mast cell activation and chemotaxis

Journal of Biological Chemistry
2013 | Journal article
DOI: 10.1074/jbc.M112.449231
EID:

2-s2.0-84875982915

Part of ISSN: 00219258 1083351X
Contributors: Hálová, I.; Dráberová, L.; Bambousková, M.; MacHyna, M.; Stegurová, L.; Smrž, D.; Dráber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Fc receptor-γ subunits with both polar or non-polar amino acids at position of T22 are capable of restoring surface expression of the high-affinity IgE receptor and degranulation in γ subunit-deficient rat basophilic leukemia cells

Molecular Immunology
2013 | Journal article
DOI: 10.1016/j.molimm.2012.08.007
EID:

2-s2.0-84866000273

Part of ISSN: 01615890 18729142
Contributors: Rashid, A.; Housden, J.E.M.; Helm, B.A.; Draber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Quantification of α-tubulin isotypes by sandwich ELISA with signal amplification through biotinyl-tyramide or immuno-PCR

Journal of Immunological Methods
2013 | Journal article
DOI: 10.1016/j.jim.2013.07.001
EID:

2-s2.0-84881556726

Part of ISSN: 00221759 18727905
Contributors: Dráberová, E.; Stegurová, L.; Sulimenko, V.; Hájková, Z.; Dráber, P.; Dráber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Mast cell chemotaxis chemoattractants and signaling pathways

Frontiers in Immunology
2012 | Journal article
DOI: 10.3389/fimmu.2012.00119
EID:

2-s2.0-84874128352

Part of ISSN: 16643224
Contributors: Halova, I.; Draberova, L.; Draber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Novel mechanism for FcεRI-mediated signal transducer and activator of transcription 5 (STAT5) tyrosine phosphorylation and the selective influence of STAT5B over mast cell cytokine production

Journal of Biological Chemistry
2012 | Journal article
DOI: 10.1074/jbc.M111.311142
EID:

2-s2.0-84862973257

Part of ISSN: 00219258 1083351X
Contributors: Pullen, N.A.; Barnstein, B.O.; Falanga, Y.T.; Wang, Z.; Suzuki, R.; Tamang, T.D.L.; Khurana, M.C.; Harry, E.A.; Draber, P.; Bunting, K.D. et al.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Transmembrane adaptor proteins in the high-affinity IgE receptor signaling

Frontiers in Immunology
2012 | Journal article
DOI: 10.3389/fimmu.2011.00095
EID:

2-s2.0-84874065322

Part of ISSN: 16643224
Contributors: Draber, P.; Halova, I.; Levi-Schaffer, F.; Draberova, L.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

1,2-propanediol-trehalose mixture as a potent quantitative real-time PCR enhancer

BMC Biotechnology
2011 | Journal article
DOI: 10.1186/1472-6750-11-41
EID:

2-s2.0-79955113113

Part of ISSN: 14726750
Contributors: Horáková, H.; Polakovičová, I.; Shaik, G.M.; Eitler, J.; Bugajev, V.; Dráberová, L.; Dráber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Rapid and sensitive detection of cytokines using functionalized gold nanoparticle-based immuno-PCR, comparison with immuno-PCR and ELISA

Journal of Immunological Methods
2011 | Journal article
DOI: 10.1016/j.jim.2011.06.012
EID:

2-s2.0-79960952778

Part of ISSN: 00221759 18727905
Contributors: Potucková, L.; Franko, F.; Bambousková, M.; Dráber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

STIM1-directed reorganization of microtubules in activated mast cells

Journal of Immunology
2011 | Journal article
DOI: 10.4049/jimmunol.1002074
EID:

2-s2.0-79251577715

Part of ISSN: 00221767 15506606
Contributors: Hájková, Z.; Bugajev, V.; Dráberová, E.; Vinopal, S.; Dráberová, L.; Janáček, J.; Dráber, P.; Dráber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Down-regulation of protein-tyrosine phosphatases activates an immune receptor in the absence of its translocation into lipid rafts

Journal of Biological Chemistry
2010 | Journal article
DOI: 10.1074/jbc.M109.052555
EID:

2-s2.0-77951224086

Part of ISSN: 00219258 1083351X
Contributors: Heneberg, P.; Dráberová, L.; Bambousková, M.; Pompach, P.; Dráber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

The transmembrane adaptor protein NTAL signals to mast cell cytoskeleton via the small GTPase Rho

European Journal of Immunology
2010 | Journal article
DOI: 10.1002/eji.201040403
EID:

2-s2.0-79952109525

Part of ISSN: 00142980 15214141
Contributors: Tůmová, M.; Koffer, A.; Šimíček, M.; Dráberová, L.; Dráber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

What precedes the initial tyrosine phosphorylation of the high affinity IgE receptor in antigen-activated mast cell?

FEBS Letters
2010 | Journal article
DOI: 10.1016/j.febslet.2010.08.045
EID:

2-s2.0-78649819212

Part of ISSN: 00145793
Contributors: Bugajev, V.; Bambousková, M.; Dráberová, L.; Dráber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Nano-PCR - Development of a new method for detection extremely low levels of proteins important in pathological processes,Nano-PCR - Vývoj novej metódy pre detekciu extrémne nízkych koncentracií bielkovín hrajúcich úlohu v patologických procesoch

Psychiatrie
2009 | Journal article
EID:

2-s2.0-67749099770

Part of ISSN: 12117579
Contributors: Franko, F.; Bambousková, M.; Potůčková, L.; Dráber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Vacuolin-1-modulated exocytosis and cell resealing in mast cells

Cellular Signalling
2009 | Journal article
DOI: 10.1016/j.cellsig.2009.04.001
EID:

2-s2.0-65549105602

Part of ISSN: 08986568
Contributors: Shaik, G.M.; Dráberová, L.; Heneberg, P.; Dráber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Engagement of phospholipid scramblase 1 in activated cells: Implication for phosphatidylserine externalization and exocytosis

Journal of Biological Chemistry
2008 | Journal article
DOI: 10.1074/jbc.M710386200
EID:

2-s2.0-44849125498

Part of ISSN: 00219258 1083351X
Contributors: Smrž, D.; Lebduška, P.; Dráberová, L.; Korb, J.; Dráber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Changes in GM1 ganglioside content and localization in cholestatic rat liver

Glycoconjugate Journal
2007 | Journal article
DOI: 10.1007/s10719-007-9030-7
EID:

2-s2.0-34248373531

Part of ISSN: 02820080 15734986
Contributors: Jirkovská, M.; Majer, F.; Šmídová, J.; Stříteský, J.; Shaik, G.M.; Dráber, P.; Vítek, L.; Mareček, Z.; Šmíd, F.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Non-apoptotic phosphatidylserine externalization induced by engagement of glycosylphosphatidylinositol-anchored proteins

Journal of Biological Chemistry
2007 | Journal article
DOI: 10.1074/jbc.M611090200
EID:

2-s2.0-34249858723

Part of ISSN: 00219258 1083351X
Contributors: Smrž, D.; Dráberová, L.; Dráber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Preformed STAT3 transducer complexes in human HepG2 cells and rat hepatocytes

Cellular Signalling
2007 | Journal article
DOI: 10.1016/j.cellsig.2007.07.018
EID:

2-s2.0-34548435060

Part of ISSN: 08986568
Contributors: Dráber, P.; Dráberová, L.; Heneberg, P.; Šmíd, F.; Farghali, H.; Dráber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Regulation of Ca<sup>2+</sup> signaling in mast cells by tyrosine-phosphorylated and unphosphorylated non-T cell activation linker

Journal of Immunology
2007 | Journal article
DOI: 10.4049/jimmunol.179.8.5169
EID:

2-s2.0-38449104425

Part of ISSN: 15506606 00221767
Contributors: Dráberová, L.; Shaik, G.M.; Volná, P.; Heneberg, P.; Tůmová, M.; Lebduška, P.; Korb, J.; Dráber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Topography of signaling molecules as detected by electron microscopy on plasma membrane sheets isolated from non-adherent mast cells

Journal of Immunological Methods
2007 | Journal article
DOI: 10.1016/j.jim.2007.08.015
EID:

2-s2.0-35548999559

Part of ISSN: 00221759
Contributors: Lebduška, P.; Korb, J.; Tůmová, M.; Heneberg, P.; Dráber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier

Regulation of microtubule formation in activated mast cells by complexes of γ-tubulin with Fyn and Syk kinases

Journal of Immunology
2006 | Journal article
DOI: 10.4049/jimmunol.176.12.7243
EID:

2-s2.0-33744913799

Part of ISSN: 00221767
Contributors: Sulimenko, V.; Dráberová, E.; Sulimenko, T.; Macůrek, L.; Richterovǎ, V.; Dráber, P.; Dráber, P.
Source: Self-asserted source
Petr Draber via Scopus - Elsevier
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