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Employment (4)

University of Wuppertal: Wuppertal, DE

2012-04 to 2014-02 | Professor (Department of Food Chemistry)
Employment
Source: Self-asserted source
Heiko Hayen

University of Wuppertal: Wuppertal, DE

2010-04 to 2012-03 | Deputy professor (Department of Food Chemistry)
Employment
Source: Self-asserted source
Heiko Hayen

Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V.: Dortmund, DE

2005-04 to 2010-03 | Scientific employee (Department of Bioanalytics)
Employment
Source: Self-asserted source
Heiko Hayen

Institute for Marine Biosciences, NRC Canada: Halifax, Nova Scotia, CA

2004-04 to 2005-03 | PostDoc
Employment
Source: Self-asserted source
Heiko Hayen

Education and qualifications (3)

University of Münster: Münster, DE

2000-10 to 2001-09 (Institute of Inorganic and Analytical Chemistry)
Education
Source: Self-asserted source
Heiko Hayen

University of Münster: Münster, DE

1999-07 to 2000-06 | Second State Exam in "Food Chemistry" (Chemisches und Veterinäruntersuchungsamt Münster)
Education
Source: Self-asserted source
Heiko Hayen

University of Münster: Münster, DE

1994-10 to 1999-04 | First state exam in "Food Chemistry" (Institute of Food Chemistry)
Education
Source: Self-asserted source
Heiko Hayen

Works (47)

Is Ferric the Same as Ferrous? Effect of Nutritionally Relevant Iron Species in C. elegans: Bioavailability, Iron Homeostasis, Oxidative Stress, and Cell Death

Journal of Agricultural and Food Chemistry
2025-02-12 | Journal article
DOI: 10.1021/acs.jafc.4c10463
Contributors: Anna Gremme; Zainab Al-Timimi Safa Flaih; Johannes Scholz; Emely Gerisch; Alicia Thiel; Gawain McColl; Heiko Hayen; Bernhard Michalke; Julia Bornhorst
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Dysfunctional copper homeostasis in Caenorhabditis elegans affects genomic and neuronal stability

Redox Biochemistry and Chemistry
2024-12 | Journal article
DOI: 10.1016/j.rbc.2024.100043
Contributors: Ann-Kathrin Weishaupt; Anna Gremme; Torben Meiners; Vera Schwantes; Karsten Sarnow; Alicia Thiel; Tanja Schwerdtle; Michael Aschner; Heiko Hayen; Julia Bornhorst
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Hyphenation of supercritical fluid chromatography and trapped ion mobility-mass spectrometry for quantitative lipidomics

Analytica Chimica Acta
2024-08 | Journal article
DOI: 10.1016/j.aca.2024.342913
Contributors: Johannes Scholz; Edward Rudt; Anna Gremme; Carina M. Gaßmöller (née Wienken); Julia Bornhorst; Heiko Hayen
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Hyphenation of Liquid Chromatography and Trapped Ion Mobility – Mass Spectrometry for Characterization of Isomeric Phosphatidylethanolamines with Focus on N-Acylated Species

Journal of the American Society for Mass Spectrometry
2024-07-03 | Journal article
DOI: 10.1021/jasms.4c00162
Contributors: Edward Rudt; Svenja Schneider; Heiko Hayen
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Proposal for a systematic naming convention for liamocins

Journal of Surfactants and Detergents
2024-05 | Journal article
DOI: 10.1002/jsde.12735
Contributors: Till Tiso; Gina Welsing; Anna Lipphardt; Daniel F. Sauer; Zhenming Chi; Lars M. Blank; Heiko Hayen
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Toxicokinetics of homosalate in humans after dermal application: applicability of oral-route data for exposure assessment by human biomonitoring

Archives of Toxicology
2024-05 | Journal article
DOI: 10.1007/s00204-024-03704-7
Contributors: Katharina E. Ebert; Peter Griem; Tobias Weiss; Thomas Brüning; Heiko Hayen; Holger M. Koch; Daniel Bury
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Synthetically-primed adaptation of Pseudomonas putida to a non-native substrate D-xylose

Nature Communications
2024-03-26 | Journal article
DOI: 10.1038/s41467-024-46812-9
Contributors: Pavel Dvořák; Barbora Burýšková; Barbora Popelářová; Birgitta E. Ebert; Tibor Botka; Dalimil Bujdoš; Alberto Sánchez-Pascuala; Hannah Schöttler; Heiko Hayen; Víctor de Lorenzo et al.
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Identification, Organic Synthesis, and Sensitive Analysis of a cis-Homosalate-Specific Exposure Biomarker

Chemical Research in Toxicology
2024-02-19 | Journal article
DOI: 10.1021/acs.chemrestox.3c00287
Contributors: Katharina E. Ebert; Vladimir N. Belov; Michael John; Tobias Weiss; Thomas Brüning; Heiko Hayen; Holger M. Koch; Daniel Bury
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Identification and quantification of biosurfactants produced by the marine bacterium Alcanivorax borkumensis by hyphenated techniques

Analytical and Bioanalytical Chemistry
2023-12 | Journal article
DOI: 10.1007/s00216-023-04972-5
Contributors: Anna Lipphardt; Tobias Karmainski; Lars M. Blank; Heiko Hayen; Till Tiso
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Quantitative Metabolism and Urinary Elimination Kinetics of Seven Neonicotinoids and Neonicotinoid-Like Compounds in Humans

Environmental Science & Technology
2023-12-05 | Journal article
DOI: 10.1021/acs.est.3c05040
Contributors: Sonja A. Wrobel; Daniel Bury; Stephan Koslitz; Heiko Hayen; Holger M. Koch; Thomas Brüning; Heiko U. Käfferlein
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Determination of Polar Lipids in Wheat and Oat by a Complementary Approach of Hydrophilic Interaction Liquid Chromatography and Reversed-Phase High-Performance Liquid Chromatography Hyphenated with High-Resolution Mass Spectrometry

Journal of Agricultural and Food Chemistry
2023-07-26 | Journal article
DOI: 10.1021/acs.jafc.3c02073
Contributors: Svenja Schneider; Simon Hammann; Heiko Hayen
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Quantitation of 6-chloronicotinic acid and 2-chloro-1,3-thiazole-5-carboxylic acid and their glycine conjugates in human urine to assess neonicotinoid exposure

Environmental Research
2023-06 | Journal article
DOI: 10.1016/j.envres.2023.115609
Contributors: Sonja A. Wrobel; Stephan Koslitz; Vladimir N. Belov; Daniel Bury; Heiko Hayen; Thomas Brüning; Holger M. Koch; Heiko U. Käfferlein
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Bacterial Lipoproteins Shift Cellular Metabolism to Glycolysis in Macrophages Causing Bone Erosion

Microbiology Spectrum
2023-06-15 | Journal article
DOI: 10.1128/spectrum.04293-22
Contributors: Minh-Thu Nguyen; Zhicheng Hu; Majd Mohammad; Hannah Schöttler; Silke Niemann; Michelle Schultz; Katarzyna Barczyk-Kahlert; Tao Jin; Heiko Hayen; Mathias Herrmann et al.
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Genomic and metabolic plasticity drive alternative scenarios for adaptingPseudomonas putidato non-native substrate D-xylose

2023-05-19 | Preprint
DOI: 10.1101/2023.05.19.541448
Contributors: Pavel Dvořák; Barbora Burýšková; Barbora Popelářová; Birgitta Ebert; Tibor Botka; Dalimil Bujdoš; Alberto Sánchez-Pascuala; Hannah Schöttler; Heiko Hayen; Víctor de Lorenzo et al.
Source: check_circle
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Determination of double bond positions in methyl ketones by gas chromatography–mass spectrometry using dimethyl disulfide derivatives

Rapid Communications in Mass Spectrometry
2023-03-30 | Journal article
DOI: 10.1002/rcm.9457
Contributors: Matti Froning; Carolin Grütering; Lars M. Blank; Heiko Hayen
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Lipidomic and Metallomic Alteration of Caenorhabditis elegans after Acute and Chronic Manganese, Iron, and Zinc Exposure with a Link to Neurodegenerative Disorders

Journal of Proteome Research
2023-03-03 | Journal article
DOI: 10.1021/acs.jproteome.2c00578
Contributors: Bastian Blume; Vera Schwantes; Michael Witting; Heiko Hayen; Philippe Schmitt-Kopplin; Patrick O. Helmer; Bernhard Michalke
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Rapid quantification of seven major neonicotinoids and neonicotinoid-like compounds and their key metabolites in human urine

Analytica Chimica Acta
2023-01 | Journal article
DOI: 10.1016/j.aca.2022.340680
Contributors: Sonja A. Wrobel; Daniel Bury; Vladimir N. Belov; Jan M. Klenk; Bernhard Hauer; Heiko Hayen; Anderson J. Martino-Andrade; Holger M. Koch; Thomas Brüning; Heiko U. Käfferlein
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Tattoo Pigment Identification in Inks and Skin Biopsies of Adverse Reactions by Complementary Elemental and Molecular Bioimaging with Mass Spectral Library Matching

Analytical Chemistry
2022-03-01 | Journal article
DOI: 10.1021/acs.analchem.1c04922
Contributors: Corinna Brungs; Robin Schmid; Carina Wolf; Tanja Berg; Ansgar Korf; Steffen Heuckeroth; Heiko Hayen; Sebastiaan van der Bent; Karen Maijer; Thomas Rustemeyer et al.
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Human metabolism and urinary excretion of seven neonicotinoids and neonicotinoid-like compounds after controlled oral dosages

Archives of Toxicology
2022-01 | Journal article
DOI: 10.1007/s00204-021-03159-0
Contributors: Sonja A. Wrobel; Daniel Bury; Heiko Hayen; Holger M. Koch; Thomas Brüning; Heiko U. Käfferlein
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Human Metabolism and Urinary Excretion Kinetics of Nonylphenol in Three Volunteers after a Single Oral Dose

Chemical Research in Toxicology
2021-11-15 | Journal article
DOI: 10.1021/acs.chemrestox.1c00301
Contributors: Benedikt Ringbeck; Vladimir N. Belov; Christoph Schmidtkunz; Katja Küpper; Wolfgang Gries; Tobias Weiss; Thomas Brüning; Heiko Hayen; Daniel Bury; Gabriele Leng et al.
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Profiling of sphingolipids in Caenorhabditis elegans by two-dimensional multiple heart-cut liquid chromatography – mass spectrometry

Journal of Chromatography A
2021-10 | Journal article
DOI: 10.1016/j.chroma.2021.462481
Contributors: Johannes Scholz; Patrick O. Helmer; Merle M. Nicolai; Julia Bornhorst; Heiko Hayen
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Determination of specific urinary nonylphenol metabolites by online-SPE-LC-MS/MS as novel human exposure biomarkers

Journal of Chromatography B
2021-07 | Journal article
DOI: 10.1016/j.jchromb.2021.122794
Contributors: Benedikt Ringbeck; Daniel Bury; Heiko Hayen; Tobias Weiss; Thomas Brüning; Holger M. Koch
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Crossref

Human metabolism and urinary excretion kinetics of di-n-butyl adipate (DnBA) after oral and dermal administration in three volunteers

Toxicology Letters
2021-06 | Journal article
DOI: 10.1016/j.toxlet.2021.02.012
Contributors: Benedikt Ringbeck; Daniel Bury; Alexandra Gotthardt; Heiko Hayen; Rainer Otter; Tobias Weiss; Thomas Brüning; Holger M. Koch
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Complementing Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry Imaging with Chromatography Data for Improved Assignment of Isobaric and Isomeric Phospholipids Utilizing Trapped Ion Mobility-Mass Spectrometry

Analytical Chemistry
2021-02-02 | Journal article
DOI: 10.1021/acs.analchem.0c03942
Contributors: Patrick O. Helmer; Ilona D. Nordhorn; Ansgar Korf; Arne Behrens; Rebecca Buchholz; Florian Zubeil; Uwe Karst; Heiko Hayen
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Investigation of cardiolipin oxidation products as a new endpoint for oxidative stress in C. elegans by means of online two-dimensional liquid chromatography and high-resolution mass spectrometry

Free Radical Biology and Medicine
2021-01 | Journal article
DOI: 10.1016/j.freeradbiomed.2020.10.019
Contributors: Patrick O. Helmer; Merle M. Nicolai; Vera Schwantes; Julia Bornhorst; Heiko Hayen
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Application of large volume injection for sensitive LC-MS/MS analysis of seven artificial sweeteners in surface waters

MethodsX
2020 | Journal article
DOI: 10.1016/j.mex.2020.101134
Contributors: Jonas Henschel; Heiko Hayen
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Hyphenation of supercritical fluid chromatography with different detection methods for identification and quantification of liamocin biosurfactants

Journal of Chromatography A
2020-11 | Journal article
DOI: 10.1016/j.chroma.2020.461584
Contributors: Karen Scholz; Anna Lipphardt; Carina M. Wienken; Till Tiso; Heiko Hayen
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Identification and structural characterization of lipid A from Escherichia coli, Pseudomonas putida and Pseudomonas taiwanensis using liquid chromatography coupled to high‐resolution tandem mass spectrometry

Rapid Communications in Mass Spectrometry
2020-11-15 | Journal article
DOI: 10.1002/rcm.8897
Contributors: Matti Froning; Patrick O. Helmer; Heiko Hayen
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Comprehensive liamocin biosurfactants analysis by reversed phase liquid chromatography coupled to mass spectrometric and charged-aerosol detection

Journal of Chromatography A
2020-09 | Journal article
DOI: 10.1016/j.chroma.2020.461404
Contributors: Karen Scholz; Maximilian Seyfried; Oliver Brumhard; Lars M. Blank; Till Tiso; Heiko Hayen
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Double bond localization in unsaturated rhamnolipid precursors 3-(3-hydroxyalkanoyloxy)alkanoic acids by liquid chromatography–mass spectrometry applying online Paternò–Büchi reaction

Analytical and Bioanalytical Chemistry
2020-09-05 | Journal article
DOI: 10.1007/s00216-020-02776-5
Contributors: Viola Jeck; Matti Froning; Till Tiso; Lars M. Blank; Heiko Hayen
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Hydroperoxylated vs Dihydroxylated Lipids: Differentiation of Isomeric Cardiolipin Oxidation Products by Multidimensional Separation Techniques

Analytical Chemistry
2020-09-01 | Journal article
DOI: 10.1021/acs.analchem.0c02605
Contributors: Patrick O. Helmer; Arne Behrens; Edward Rudt; Uwe Karst; Heiko Hayen
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Complementary approach for analysis of phospholipids by liquid chromatography hyphenated to elemental and molecular mass spectrometry

Analytical Science Advances
2020-06 | Journal article
DOI: 10.1002/ansa.20190009
Contributors: Christian Vosse; Georgina M. Thyssen; Michael Sperling; Uwe Karst; Heiko Hayen
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Mass spectrometric investigation of cardiolipins and their oxidation products after two-dimensional heart-cut liquid chromatography

Journal of Chromatography A
2020-05 | Journal article
DOI: 10.1016/j.chroma.2020.460918
Contributors: Patrick O. Helmer; Carina M. Wienken; Ansgar Korf; Heiko Hayen
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Analysis of artificially oxidized cardiolipins and monolyso‐cardiolipins via liquid chromatography/high‐resolution mass spectrometry and Kendrick mass defect plots after hydrophilic interaction liquid chromatography based sample preparation

Rapid Communications in Mass Spectrometry
2020-01-15 | Journal article
DOI: 10.1002/rcm.8566
Contributors: Patrick O. Helmer; Ansgar Korf; Heiko Hayen
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Expanding the Kendrick Mass Plot Toolbox in MZmine 2 to Enable Rapid Polymer Characterization in Liquid Chromatography−Mass Spectrometry Data Sets

Analytical Chemistry
2020-01-07 | Journal article
DOI: 10.1021/acs.analchem.9b03863
Contributors: Ansgar Korf; Thierry Fouquet; Robin Schmid; Heiko Hayen; Sebastian Hagenhoff
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Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth

eLife
2019-12-23 | Journal article
DOI: 10.7554/eLife.51063
Contributors: Marta Palomo-Guerrero; Rut Fadó; Maria Casas; Marta Pérez-Montero; Miguel Baena; Patrick O Helmer; José Luis Domínguez; Aina Roig; Dolors Serra; Heiko Hayen et al.
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Localization of double‐bond positions in lipids by tandem mass spectrometry succeeding high‐performance liquid chromatography with post‐column derivatization

Rapid Communications in Mass Spectrometry
2019-05 | Journal article
DOI: 10.1002/rcm.8262
Contributors: Viola Jeck; Ansgar Korf; Christian Vosse; Heiko Hayen
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Lipid Species Annotation at Double Bond Position Level with Custom Databases by Extension of the MZmine 2 Open-Source Software Package

Analytical Chemistry
2019-04-16 | Journal article
DOI: 10.1021/acs.analchem.8b05493
Contributors: Ansgar Korf; Viola Jeck; Robin Schmid; Patrick O. Helmer; Heiko Hayen
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Mass spectrometric characterization of siderophores produced by Pseudomonas taiwanensis VLB120 assisted by stable isotope labeling of nitrogen source

BioMetals
2018-10-28 | Journal article
DOI: 10.1007/s10534-018-0122-6
Contributors: Karen Scholz; Till Tiso; Lars M. Blank; Heiko Hayen
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LC/MS analysis of vitamin D metabolites by dielectric barrier discharge ionization and a comparison with electrospray ionization and atmospheric pressure chemical ionization

Analytical and Bioanalytical Chemistry
2018-08-26 | Journal article
DOI: 10.1007/s00216-018-1137-0
Contributors: Sebastian Hagenhoff; Heiko Hayen
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Ambient desorption/ionization mass spectrometry: evolution from rapid qualitative screening to accurate quantification tool

Analytical and Bioanalytical Chemistry
2018-07-21 | Journal article
DOI: 10.1007/s00216-018-1023-9
Contributors: Jacob T. Shelley; Sunil P. Badal; Carsten Engelhard; Heiko Hayen
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Screening of semifluorinated n‐alkanes by gas chromatography coupled to dielectric barrier discharge ionization mass spectrometry

Rapid Communications in Mass Spectrometry
2018-07-15 | Journal article
DOI: 10.1002/rcm.8139
Contributors: Sebastian Hagenhoff; Ansgar Korf; Ullrich Markgraf; Sebastian Brandt; Alexander Schütz; Joachim Franzke; Heiko Hayen
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Three‐dimensional Kendrick mass plots as a tool for graphical lipid identification

Rapid Communications in Mass Spectrometry
2018-06-30 | Journal article
DOI: 10.1002/rcm.8117
Contributors: Ansgar Korf; Christian Vosse; Robin Schmid; Patrick O. Helmer; Viola Jeck; Heiko Hayen
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De-novo identification of specific exposure biomarkers of the alternative plasticizer di(2-ethylhexyl) terephthalate (DEHTP) after low oral dosage to male volunteers by HPLC-Q-Orbitrap-MS

Biomarkers
2018-02-17 | Journal article
DOI: 10.1080/1354750X.2017.1410856
Contributors: Frederik Lessmann; Daniel Bury; Tobias Weiss; Heiko Hayen; Thomas Brüning; Holger M. Koch
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Determination of Urinary Metabolites of the Emerging UV Filter Octocrylene by Online-SPE-LC-MS/MS

Analytical Chemistry
2018-01-02 | Journal article
DOI: 10.1021/acs.analchem.7b03996
Contributors: Daniel Bury; Vladimir N. Belov; Yulin Qi; Heiko Hayen; Dietrich A. Volmer; Thomas Brüning; Holger M. Koch
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Structural characterization of pyoverdines produced by Pseudomonas putida KT2440 and Pseudomonas taiwanensis VLB120

BioMetals
2017-08-19 | Journal article
DOI: 10.1007/s10534-017-0029-7
Contributors: Matthias Baune; Yulin Qi; Karen Scholz; Dietrich A. Volmer; Heiko Hayen
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Determination of Peroxide Explosive TATP and Related Compounds by Dielectric Barrier Discharge Ionization-Mass Spectrometry (DBDI-MS)

Analytical Chemistry
2017-04-04 | Journal article
DOI: 10.1021/acs.analchem.7b00233
Contributors: Sebastian Hagenhoff; Joachim Franzke; Heiko Hayen
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